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Written By Veda Maddala , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Vibrex 40 Tablet is used to treat the major depressive disorder. It contains Vilazodone which increases serotonin levels and helps regulate mood. In some cases, this medicine may cause side effects such as diarrhoea, nausea, vomiting, and insomnia (sleeping problems). Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Composition :

VILAZODONE-40MG

Manufacturer/Marketer :

Strides Shasun Ltd

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Vibrex 40 Tablet

Vibrex 40 Tablet belongs to the class of medications called ‘antidepressants’ used to treat the major depressive disorder (MDD) or clinical depression. Major depressive disorder, also known as clinical depression, is a mental health disorder characterized by persistent and intense loneliness (nearly every day for at least two weeks).

Vibrex 40 Tablet contains ‘Vilazodone’, which increases serotonin levels (a chemical messenger) in the brain. Serotonin is a hormone that helps improve mood, well-being, and happiness. Hence, an increase in serotonin levels helps to decrease symptoms of depression.

You should take this medicine exactly as prescribed by your doctor. Vibrex 40 Tablet may cause side effects such as diarrhoea, nausea, vomiting, and insomnia (sleeping problems). These side effects usually resolve without requiring any treatment. However, if any of these side effects persist or worsen, inform your doctor immediately.

It is not recommended to take Vibrex 40 Tablet if you are allergic to any contents of it. Before taking Vibrex 40 Tablet , inform your doctor if you have seizures (fits), alcohol abuse, liver or kidney disease, bleeding disorder, glaucoma (an eye condition), and bipolar disorder. Vibrex 40 Tablet should be used with caution in pregnant and breastfeeding women. Vibrex 40 Tablet is not recommended for children or adolescents below 18 years of age as this medicine increase the risk of suicidal tendencies. No dose adjustments are required for elderly patients. It is not recommended to take alcohol as it increases the risk of side effects. Do not drive or operate heavy machinery as it may decrease your alertness.

Uses of Vibrex 40 Tablet

Treatment of Major depressive disorder or Clinical depression

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Vibrex 40 Tablet is used in the treatment of major depressive disorder. It increases the serotonin hormone levels, which improves mood, energy, and feelings of well-being. It can decrease the number and frequency of depressive episodes. It helps in reducing the symptoms of depression effectively and improves quality-of-life. It can also be used to treat anxiety.

How Vibrex 40 Tablet Works

Vibrex 40 Tablet contains ‘Vilazodone’, which increases serotonin levels (a chemical messenger) in the brain. Serotonin is a hormone that helps improve mood, well-being, and happiness. Hence, an increase in serotonin levels helps to decrease symptoms of depression.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Vibrex 40 Tablet

  • Nausea
  • Vomiting
  • Insomnia (difficulty in sleeping)
  • Dizziness
  • Diarrhoea

What if I have taken an overdose of Vibrex 40 Tablet

Take Vibrex 40 Tablet only as prescribed by the doctor. Avoid exceeding the recommended dose as it could lead to an overdose. Symptoms of overdose may include serotonin syndrome, lethargy, restlessness, hallucinations, and disorientation. If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

It is not recommended to take any monoamine oxidase inhibitors (MAOIs) within the 14 days after stopping Vibrex 40 Tablet or do not take Vibrex 40 Tablet within 14 days after stopping MAOIs. The interaction between these two drugs can be fatal sometimes. Vibrex 40 Tablet may worsen depression and increase suicidal tendencies, so inform your doctor immediately if you notice any unusual changes in your mood or behaviour. Vibrex 40 Tablet may cause serotonin syndrome or neuroleptic malignant-like syndrome, which is characterized by symptoms such as high blood pressure, agitation, confusion, excess sweating, and increased heart rate. In such cases, the doctor may discontinue treatment and provide supportive therapy. Vibrex 40 Tablet may increase bleeding risk when used along with nonsteroidal anti-inflammatory drugs (NSAIDs), aspirin, or blood thinners. Vibrex 40 Tablet may activate mania (abnormally heightened response or energy levels), so patients should be screened regularly for bipolar disorder. Vibrex 40 Tablet may cause hyponatremia (decreased sodium levels in the blood) when used in people with the syndrome of inappropriate antidiuretic hormone secretion (SIADH), a condition in which the body retains too much water. Do not stop taking Vibrex 40 Tablet even if you feel better without your doctor’s advice. Abrupt stopping this medicine may cause withdrawal symptoms such as sleep problems, irritability, and excessive sweating. The doctor may gradually reduce the dose before completely stopping the treatment from avoiding withdrawal reactions.

Drug-Drug Interactions

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VilazodoneSafinamide
Critical
VilazodoneProcarbazine
Critical

Drug-Drug Interactions

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VilazodoneSafinamide
Critical
How does the drug interact with Vibrex 40 Tablet 10's:
Taking Safinamide with Amitriptyline can increase the risk of serotonin syndrome (A condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Vibrex 40 Tablet 10's with Safinamide together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as severe confusion, hallucinations, fits, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasms or stiffness, shaking, incoordination, stomach cramps, nausea, vomiting, and loose stools. Do not discontinue any medications without consulting a doctor.
VilazodoneProcarbazine
Critical
How does the drug interact with Vibrex 40 Tablet 10's:
When Vibrex 40 Tablet 10's is taken with Procarbazine, may increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increases in your body).

How to manage the interaction:
Taking Vibrex 40 Tablet 10's with Procarbazine together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as severe confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasms or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting a doctor.
VilazodoneTranylcypromine
Critical
How does the drug interact with Vibrex 40 Tablet 10's:
Taking Vibrex 40 Tablet 10's with Tranylcypromine can increase the risk of serotonin syndrome (a A condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Vibrex 40 Tablet 10's with Tranylcypromine can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucination (seeing and hearing things that do not exist), fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting a doctor.
VilazodoneSelegiline
Critical
How does the drug interact with Vibrex 40 Tablet 10's:
Co-administration of Vibrex 40 Tablet 10's is taken with Selegiline, which increases the serotonin levels (A condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Taking Vibrex 40 Tablet 10's with Selegiline together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as severe confusion, hallucination, fits, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasms or stiffness, shaking, incoordination, stomach cramp, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting a doctor.
VilazodoneRasagiline
Critical
How does the drug interact with Vibrex 40 Tablet 10's:
Taking Vibrex 40 Tablet 10's and Rasagiline can increase the risk of serotonin syndrome (A condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Vibrex 40 Tablet 10's with Rasagiline together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as severe confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasms or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting a doctor.
VilazodoneFurazolidone
Critical
How does the drug interact with Vibrex 40 Tablet 10's:
When Vibrex 40 Tablet 10's is taken with Furazolidone, may increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increases in your body).

How to manage the interaction:
Taking Vibrex 40 Tablet 10's with Furazolidone together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as severe confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasms or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting a doctor.
VilazodonePhenelzine
Critical
How does the drug interact with Vibrex 40 Tablet 10's:
When Vibrex 40 Tablet 10's is taken with Phenelzine, may increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increases in your body).

How to manage the interaction:
Taking Vibrex 40 Tablet 10's with Phenelzine together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as severe confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasms or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting a doctor.
VilazodoneLinezolid
Critical
How does the drug interact with Vibrex 40 Tablet 10's:
When Vibrex 40 Tablet 10's is taken with Linezolid, may increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increases in your body).

How to manage the interaction:
Taking Vibrex 40 Tablet 10's with Linezolid together can result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as severe confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasms or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting a doctor.
VilazodoneIsocarboxazid
Critical
How does the drug interact with Vibrex 40 Tablet 10's:
When Vibrex 40 Tablet 10's is taken with Isocarboxazid, may increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increases in your body).

How to manage the interaction:
Taking Vibrex 40 Tablet 10's with Isocarboxazid together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as severe confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasms or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting a doctor.
VilazodoneTroleandomycin
Severe
How does the drug interact with Vibrex 40 Tablet 10's:
Co-administration of Troleandomycin with Vibrex 40 Tablet 10's may increase the blood levels and effects of Vibrex 40 Tablet 10's.

How to manage the interaction:
Taking Vibrex 40 Tablet 10's with Troleandomycin together can possibly result in an interaction, but it can be taken if a doctor has advised it. If you have any of these symptoms - your condition, diarrhea, feeling sick, throwing up, dry mouth, feeling dizzy or having trouble sleeping - make sure to call a doctor right away. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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VILAZODONE-40MGHerbal products/medicines
Moderate

Drug-Food Interactions

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VILAZODONE-40MGHerbal products/medicines
Moderate
Common Foods to Avoid:
St. John’S Wort

How to manage the interaction:
Taking Vibrex 40 Tablet 10's with St. John's Wort significantly increases the metabolism of Vibrex 40 Tablet 10's. Avoid taking Vibrex 40 Tablet 10's with St. John's Wort.

Diet & Lifestyle Advise

  • Maintain a healthy diet and exercise regularly helps in improving overall health and boosts self-esteem.
  • Regularly attend therapy sessions.
  • Perform meditation and yoga. This helps in relieving stress and provides relaxation.
  • Follow a regular sleep pattern to improve the amount and quality of sleep you get.
  • Include foods rich in omega fatty acids such as fish, nuts, fresh fruits, vegetables, and olive oils.
  • Neurotransmitters are made up of amino acids. Amino acid-rich foods such as meat, dairy products, and certain fruits and vegetables help maintain neurotransmitters' proper maintenance.
  • Complex carbohydrates help in stimulating serotonin (a feel-good neurotransmitter). These include whole grains, legumes, spinach, broccoli, oranges, and pears.
  • Exercising helps in the production of the body’s natural antidepressants. It also helps in relieving stress, improving mood, boosts self-esteem, and provides restful sleep.
  • Avoid smoking and alcohol consumption.
  • Learn about your condition, understand the risk factors, and follow the doctor’s treatment plan.

Habit Forming

No

Therapeutic Class

ANTIDEPRESSANT

Vibrex 40 Tablet Substitute

Substitutes safety advice
  • Valz 40 Tablet 10's

    30.89per tablet
  • Valzpen-40 Tablet 10's

    30.78per tablet
  • Minidep 40Mg Tablet

    by AYUR

    31.49per tablet
  • Vizatex-40 Tablet

    by AYUR

    29.25per tablet
  • Vinsure 40 Tablet

    by AYUR

    29.16per tablet
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Alcohol

Caution

Avoid consumption of alcohol as it may interact with Vibrex 40 Tablet and increase the risk of side-effects.

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Pregnancy

Caution

Vibrex 40 Tablet should be used in pregnant women only when clinically needed and if the benefits outweigh the risks. Please consult your doctor. Your doctor will weigh the benefits and potential risks before prescribing Vibrex 40 Tablet .

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Breast Feeding

Caution

Vibrex 40 Tablet should be used in breastfeeding mothers when clinically needed and if the benefits outweigh the risks. Please consult your doctor. Your doctor will weigh the benefits and potential risks before prescribing Vibrex 40 Tablet .

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Driving

Caution

Do not drive or operate heavy machinery as Vibrex 40 Tablet may affect alertness.

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Liver

Caution

Vibrex 40 Tablet should be used with caution in patients with severe liver diseases. The dose may have to be adjusted by your doctor.

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Kidney

Caution

Vibrex 40 Tablet should be used with caution in patients with severe kidney diseases. The dose may have to be adjusted by your doctor.

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Children

Unsafe

Vibrex 40 Tablet is not recommended in children below 12 years of age.

FAQs

Vibrex 40 Tablet is used to treat major depressive disorder or clinical depression.
Vibrex 40 Tablet contains 'vilazodone' which is an antidepressant. It works by restoring the levels of serotonin in the brain. Serotonin is a hormone or chemical messenger in the brain responsible for improving energy, mood, and emotion levels.
Vibrex 40 Tablet may cause side effects such as diarrhoea, nausea, vomiting, and insomnia (sleeping problems). These side effects usually resolve without requiring any treatment. However, if any of these side effects persist or worsen, inform your doctor immediately.
In case you miss a dose of Vibrex 40 Tablet , do not take a double dose of Vibrex 40 Tablet . If you remember the missed dose before sleeping, take it at that time and take Vibrex 40 Tablet at the same time the next day, which were you taking earlier. If you remember the missed dose the next day, leave the skipped dose, and continue with the next dose.
Yes,Vibrex 40 Tablet cause withdrawal symptoms, if you suddenly stop your medicine even if u feel better. Please reach out a health care professional.
Vibrex 40 Tablet cannot be used in epilepsy or are having electroconvulsive treatment .Vibrex 40 Tablet may increase your risk of having a seizure.
Vibrex 40 Tablet should be used with caution in patients with alcohol abuse, seizures (fits), liver or kidney disease, bleeding disorder, glaucoma (an eye condition), and bipolar disorder, as the Vibrex 40 Tablet may worsen these conditions.
No, Vibrex 40 Tablet is not a narcotic. It is an antidepressant medication that belongs to the class of selective serotonin reuptake inhibitors (SSRIs).
Yes, Vibrex 40 Tablet can help with anxiety. While it is primarily used to treat major depressive disorders, it has also been shown to be effective in reducing symptoms of anxiety.
Vibrex 40 Tablet is not approved for use in children and adolescents under 18 years old due to the increased risk of suicidal thoughts and behavior.
Before taking Vibrex 40 Tablet , it's essential to inform your doctor about your medical history, including any ongoing medications and existing conditions such as seizures, liver or kidney disease, bipolar disorder, or pregnancy. Additionally, share your history of suicidal thoughts or behavior and any relevant family history. By sharing this information, you'll help your doctor avoid potential drug interactions, minimize side effects, and choose the best treatment for you.
Major Depressive Disorder, or clinical depression, is characterized by a persistent depressed mood that lasts nearly every day for two weeks, interfering with daily activities. Symptoms include feeling sad or hopeless, loss of interest in usual activities, weight/appetite changes, sleep disturbances, agitation, fatigue, guilt/worthlessness, concentration problems, and suicidal thoughts/behavior, with at least five of these symptoms present.

Country of origin

India

Manufacturer/Marketer address

Strides Shasun Limited, (Formerly Strides Arcolab Limited), Strides House, Bilekahalli, Bannerghatta Road, Bangalore €“ 560076, India
Other Info - VIB0053

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