Vezynda Soft Gelatin Suppository

Vezynda Soft Gelatin Suppository is used to treat vaginal infections caused by bacteria (bacterial vaginosis), yeast infection (candidiasis) and parasitic infections (trichomoniasis). Bacterial vaginosis is caused by the change in the normal balance of vaginal bacteria. Vaginal yeast infection or Candidiasis is the infection of the vagina and tissues at the opening of the vagina (vulva). Trichomoniasis is a sexually transmitted infection caused by a parasite. Symptoms of a vaginal infection include itching, odour and abnormal heavy white discharge from the vagina.

Vezynda Soft Gelatin Suppository comprises two medicines, namely: 'Clindamycin' (antibiotic) and 'Clotrimazole' (antifungal). Clindamycin belongs to the lincomycin antibiotic group that works by inhibiting bacterial protein synthesis, which is required for the survival of the bacteria. As a result, it inhibits bacterial growth but does not kill them (bacteriostatic effect). On the other hand, Clotrimazole belongs to the imidazole antifungal group, which kills fungi by causing holes in their cell membrane, thereby leaking all content out. 

Use Vezynda Soft Gelatin Suppository as suggested by your doctor. Common side effects of Vezynda Soft Gelatin Suppository include a burning sensation, irritation and itching. These side effects may not occur in every patient using this medication and differ individually. If the side effects persist longer or worsen, please seek a doctor's advice.

Inform your doctor if you are allergic to Vezynda Soft Gelatin Suppository or any of its components. Let your doctor know if you have any liver, kidney and gastrointestinal diseases (diarrhoea and colitis, an inflammation of the colon), allergic conditions (asthma, hay fever, eczema), diabetes and immune system problems (HIV-AIDS). Clotrimazole in Vezynda Soft Gelatin Suppository may weaken rubber products' activities of contraceptive devices, latex condoms, diaphragms and cervical caps. Pregnant and breastfeeding women should consult a doctor before using Vezynda Soft Gelatin Suppository.

Vezynda Soft Gelatin Suppository is used to treat vaginal infections like bacterial vaginosis (BV), candidiasis, and trichomoniasis. It comprises two medicines: 'Clindamycin' (antibiotic) and 'Clotrimazole' (antifungal). Clindamycin is an antibiotic drug and works by inhibiting bacterial protein synthesis, which inhibits bacterial growth. It shows a bacteriostatic effect, which stops bacterial reproduction. Clotrimazole is an imidazole antifungal medication that stops the growth of fungi by causing damage and leakage to the fungal cell membrane. Together Vezynda Soft Gelatin Suppository treats vaginal infections caused by bacteria, yeast and parasites preventing white discharge, itchiness and inflammation in the genitourinary area. 

• Burning sensation
• Irritation
• Itching

Please inform your doctor if you use any prescription, non-prescription medicines, including vitamin and herbal supplements before using Vezynda Soft Gelatin Suppository. Do not use Vezynda Soft Gelatin Suppository if you are allergic to Vezynda Soft Gelatin Suppository or any of its components. Let your doctor know if have any liver, kidney and gastrointestinal diseases (diarrhoea and colitis, an inflammation of the colon), allergic conditions (asthma, hay fever, eczema), diabetes and immune system problems (HIV-AIDS). It is advised to use Vezynda Soft Gelatin Suppository under your doctor's supervision if you use other azole antifungal medicines. Clotrimazole and mineral oil additive in Vezynda Soft Gelatin Suppository may weaken rubber product's activity (such as latex condoms, diaphragms, cervical caps).

Drug-Drug Interaction: Vezynda Soft Gelatin Suppository may interact with anaesthetic agents/skeletal muscle relaxants (atracurium, cisatracurium, doxacurium, mivacurium, pancuronium, pipecuronium, rapacuronium, rocuronium, vecuronium, succinylcholine, tubocurarine, and metocurine) and respiratory drugs (budesonide, formoterol). 

Drug-Food Interaction: No interaction found/established.

Drug-Disease Interaction: Before using Vezynda Soft Gelatin Suppository, let your doctor know if have any liver, kidney, and gastrointestinal diseases (diarrhoea and colitis, an inflammation of the colon), allergic conditions (asthma, hay fever, eczema), diabetes, and immune system problems (HIV-AIDS).

• ATRACURIUM
• CISATRACURIUM
• DOXACURIUM
• MIVACURIUM
• PANCURONIUM
• PIPECURONIUM
• RAPACURONIUM
• ROCURONIUM
• VECURONIUM
• SUCCINYLCHOLINE
• TUBOCURARINE
• METOCURINE
• BUDESONIDE
• FORMOTEROL

• Avoid frequent douching to maintain the natural moisture in the vagina.
• Use mild soap while taking baths and prefer warm baths.
• Avoid harsh products on your skin.
• Manage stress, eat healthily, drink plenty of water, exercise regularly and get plenty of sleep.
• Avoid or limit the intake of alcohol and caffeine.
• Wear under cotton underwear and pantyhose with cotton crotch which helps to prevent vaginal inflammation and irritation.

• Ask your partner to use condoms during sexual intercourse, which will help to prevent the further spread of sexually transmitted infections like gonorrhoea if exists presently.

• Proper hygiene and regular cleaning/washing of the genitourinary area with anti-infective wash is advisable.

Vaginal infection: It is also referred to as ‘Vaginitis’, which can cause infection or inflammation of the vagina or external part of the vagina, known as the vulva. Vaginal infections are generally caused due to bacteria, yeast and parasites. White thick heavy discharge, foul odour, and intense itchiness around the genitourinary area are the main characteristics of vaginal infections.

Vaginal bacterial infection: It causes a greyish-white or yellow discharge with a fish-like odour that can be observed after sexual intercourse.

Vaginal yeast infection: It usually produces intense itching with sometimes white viscous discharge.

Vaginal Trichomoniasis: It is a parasitic infection that produces intense vaginal itching with a foul odour. Vaginal discharge colour is usually greenish-yellow.