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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 9, 2024 | 12:40 PM IST
Vesiact Tablet is used in the treatment of overactive bladder (OAB) symptoms. It contains Solifenacin, which relaxes the urinary bladder muscles, which in turn decreases the activity of the overactive bladder. It stops these sudden contractions of urinary bladder muscles, thereby enabling control over urination. Thus, it increases the amount and volume of urination that can be held by your bladder. It may cause common side effects such as dry mouth, blurred vision, constipation, nausea, dyspepsia (indigestion), abdominal pain, burping or belching, heartburn, and stomach upset. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Prescription drug

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Composition

SOLIFENACIN-5MG

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Apr-26

for this medicine

About Vesiact Tablet

Vesiact Tablet belongs to the group of medications called ‘urinary antagonists' or 'antispasmodics' primarily used in the treatment of overactive bladder (OAB) symptoms. Overactive bladder is a condition in which the urinary bladder muscles constrict uncontrollably, thereby causing an urgent need to urinate, frequent urination, and inability to control urination. Besides this, Vesiact Tablet is also used for the treatment of neurogenic detrusor overactivity (a bladder control condition caused by neurological problems) in children 2 years and above.

Vesiact Tablet contains ‘Solifenacin’ that relaxes the urinary bladder muscles, which in turn decreases the activity of the overactive bladder. In an overactive bladder, muscle contractions occur before the full expansion of the bladder, causing the patient to have frequent urges to urinate. Vesiact Tablet stops these sudden contractions of urinary bladder muscles, thereby enabling control over urination. Thus, it increases the amount and volume of urination that can be held by your bladder.

Take Vesiact Tablet as prescribed by the doctor. Common side effects of Vesiact Tablet are dry mouth, blurred vision, constipation, nausea, dyspepsia (indigestion), abdominal pain, burping or belching, heartburn, and stomach upset. Inform your doctor if these side effects do not go away or get worse.

Do not take Vesiact Tablet if you are allergic to ‘solifenacin’ or any other ingredients present in it. Before taking Vesiact Tablet , inform your doctor if you have kidney disease, liver disease, bladder blockage, myasthenia gravis (a muscle disease), stomach or bowel problems (including constipation), glaucoma (increased pressure in the eye causing loss of vision), or a history of heart rhythm problems (including QT prolongation). Also, inform your doctor if you are pregnant or breastfeeding. Inform your doctor if you have an intolerance to sugars, as this medicine contains lactose. Do not take grapefruit or grapefruit juice with this medication. Avoid driving or operating heavy machinery, as this medicine may cause dizziness.

Uses of Vesiact Tablet

Treatment of Overactive bladder (urinary incontinency).

Medicinal Benefits

Vesiact Tablet contains ‘solifenacin’, which belongs to the class of medications called 'anticholinergics'. It can decrease the activity of the overactive bladder. In an overactive bladder, muscle contractions occur before the full expansion of the bladder, causing the patient to have frequent urges to urinate. Vesiact Tablet can stop these sudden contractions of bladder muscles. It enables control over urination and increases the amount of urine that can be held by your bladder.

Directions for Use

Take the medicine with or without food as advised by the doctor. Swallow the tablet as a whole with a glass of water. Do not crush, break or chew it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Vesiact Tablet

  • Dry mouth

  • Blurred vision

  • Constipation

  • Nausea

  • Dyspepsia (indigestion)

  • Urinary tract infections

  • Blurred vision

  • Abdominal pain

  • Burping or belching

  • Heartburn

  • Stomach upset

Drug Warnings

Do not take Vesiact Tablet if you are allergic to ‘solifenacin’ or any contents of it. Before taking Vesiact Tablet , inform your doctor if you are pregnant or breastfeeding or if you have kidney disease, liver disease, bladder blockage, controlled narrow-angle glaucoma, or stomach or bowel problems (including constipation), or a history of heart rhythm problems (including QT prolongation). Vesiact Tablet has lactose, so inform your doctor if you have an intolerance to any sugars. Vesiact Tablet may cause dizziness or blurred vision. So, do not drive or operate any heavy machinery. It can increase body temperature by decreasing sweating. So, avoid hot weather or doing strenuous exercise as this may cause overheating leading to unwanted effects. 

Drug Interactions

Drug-Drug interactions: Vesiact Tablet may interact with other anticholinergic medicines, cholinergic drugs,  gastrointestinal agents (metoclopramide and cisapride), antifungal drugs (ketoconazole and itraconazole), drugs used to treat HIV (ritonavir and nelfinavir), antihypertensives (verapamil and diltiazem), antibiotic (rifampicin), antiepileptic drugs (phenytoin and carbamazepine), and bisphosphonates.

Drug-Food interactions: Do not take grapefruit or grapefruit juice while using Vesiact Tablet .

Drug-Disease interactions: Vesiact Tablet should be used with caution in patients with urinary retention (inability to urinate), severe stomach or bowel conditions, myasthenia gravis (a muscle disease), glaucoma (eye problem), kidney dialysis, severe liver disease, and severe kidney disease.

Drug-Drug Interactions Checker List

  • METOCLOPRAMIDE
  • CISAPRIDE
  • KETOCONAZOLE
  • RITONAVIR
  • NELFINAVIR
  • ITRACONAZOLE
  • VERAPAMIL
  • DILTIAZEM
  • RIFAMPICIN
  • PHENYTOIN
  • CARBAMAZEPINE

Habit Forming

No

Diet & Lifestyle Advise

  • Eat fresh fruits like pears, banana, citrus fruits, and green vegetables like beans and potatoes. 

  • Try to take cranberry juice as it helps in minimizing urinary infections. 

  • Avoid coffee, tea, and carbonated drinks which contains caffeine. 

  • Do not consume processed, fried, or spicy foods, as these foods can irritate your bladder. 

  • Limit alcohol intake as it can increase the risk of side-effects.

  • Quit smoking and exercise regularly. 

Special Advise

  • Vesiact Tablet is not recommended for the children less than 2 years of age.

  • Intake of Vesiact Tablet can make you sweat less, thereby increasing the chance of having a heat stroke in summer. So avoid doing tasks which may cause to overheat. 

  • Intake of Vesiact Tablet may occasionally cause blurry vision and dizziness so avoid driving a motor vehicle, operate heavy machinery and performing hazardous tasks which require mental alertness as well. 

 

Disease/Condition Glossary

Overactive bladder (OAB): In normal conditions, when the urinary bladder is filled with urine, it sends a message to the brain that an individual is ready to urinate. During the urination process, bladder muscles contract, which ultimately leads to a uniform flow of urine. Contrary to this, in an Overactive bladder (OAB), the urinary bladder muscles start contracting before the urine is filled in the urinary bladder, thereby causing frequent urges to urinate. Vesiact Tablet prevents these sudden bladder muscle contractions and increases the volume and amount of urine that the bladder can hold. Thus, Vesiact Tablet helps to control the release of urine and helps reduce symptoms of OAB like a strong urge to urinate, frequent urination and reduced urine flow.

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Alcohol

Caution

Avoid taking alcohol as it increases the risk of side-effects.

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Pregnancy

Unsafe

Vesiact Tablet is a category C medicine. It should be used in pregnant women if the benefits outweigh the risks.

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Breast Feeding

Caution

Vesiact Tablet should be used in breastfeeding mothers only if clinically needed.

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Driving

Caution

Vesiact Tablet may cause dizziness and blurred vision. So, avoid driving or operating heavy machinery after using Vesiact Tablet .

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Liver

Caution

Vesiact Tablet should be used with caution in patients with liver diseases. Dose adjustments may be necessary.

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Kidney

Caution

Vesiact Tablet should be used with caution in patients with kidney diseases. Dose adjustments may be necessary.

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Children

Caution

Vesiact Tablet should not be used in children below 12 years of age unless prescribed by a doctor.

Country of origin

India

Manufacturer/Marketer address

16th Floor, Godrej BKC, Plot ? C, ?G? Block, Bandra-Kurla Complex, Bandra (East), Mumbai ? 400 051, India.
Other Info - VES0007

Author Details

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FAQs

Vesiact Tablet is primarily used in the treatment of overactive bladder (OAB) symptoms. Besides this, Vesiact Tablet is also used for the treatment of neurogenic detrusor overactivity (a bladder control condition caused by neurological problems) in children 2 years and above.
Vesiact Tablet is used to treat an overactive bladder in which an individual is unable to control urination and always have a strong urge to urinate. Vesiact Tablet prevents these sudden bladder muscle contractions and increasing the volume and amount of urine that the bladder can hold. Thus, Vesiact Tablet helps to control the release of urine and helps reduce symptoms of OAB like a strong urge to urinate, frequent urination and reduced urine flow.
Vesiact Tablet may cause blurred vision in some cases. Consult your doctor immediately if this condition persists or worsens while using this medicine.
Ketoconazole is an antifungal medicine and it may interact with Vesiact Tablet . So, inform your doctor about all the prescription and non-prescription medicines before taking Vesiact Tablet to avoid unwanted effects.
Dry mouth, constipation, urinary tract infection and blurred vision are some of the common side effects of Vesiact Tablet .
If you have bladder problems, stomach problems, narrow-angle glaucoma, liver/kidney problems and irregular heartbeat, please contact a doctor before taking Vesiact Tablet .
Dry mouth is the most common side effects of Vesiact Tablet , so you can drink plenty of fluids or water, suck hard candy or ice chips, chew (sugarless) gum, or use a saliva substitute. However, if you are a kidney patient before taking any fluid or electrolytes, it is better to consult a doctor.
If you are taking antidiabetic medicines (pramlintide), potassium tablets and antifungals (like itraconazole, ketoconazole), among others, let your doctor know about these drugs before using Vesiact Tablet . These medicines may affect the working of Vesiact Tablet and slow its excretion from the body.
Overactive bladder is a condition in which the urinary bladder muscles constrict uncontrollably, thereby causing an urgent need to urinate, frequent urination, and inability to control urination.
Vesiact Tablet starts to work within 3 to 8 hours, but it can take up to 4 to 6 weeks to work fully.
Take Vesiact Tablet at around the same time(s) every day. Follow the directions on your prescription label or as directed by the physician.
Vesiact Tablet is a safe and effective medication if prescribed by a doctor. However, it is not suitable for everyone, especially those with specific underlying conditions. Please discuss with your doctor whether it is appropriate.
A marked increased risk of dementia was associated with the use of Vesiact Tablet . Please seek medical attention if you have experienced any symptoms or if they persist.
Vesiact Tablet does not affect any type of contraception.
This medication is normally taken on a long-term basis to help regulate your symptoms. Your doctor will check in every 6 to 12 months to evaluate if you should continue taking it.
If you have urinary incontinence, it can help to cut down on alcohol and drinks containing caffeine, such as coffee, tea, cola and energy drinks.
Vesiact Tablet should not make you lose or gain weight. However, very rarely Vesiact Tablet can make you feel less hungry, so you may lose weight.
Do not take solifenacin for longer than is necessary. Every 6 to 12 months, your doctor will determine whether your treatment is still required. In older adults taking solifenacin, there may be an increased chance of confusion and dementia worsening. If you're concerned, talk to your doctor.
Talk to your doctor if you're thinking about stopping your medicine. Do not stop taking solifenacin without talking to your doctor first. If you've been taking it for at least six months, your doctor may suggest that you stop for up to 4 weeks to see how your symptoms change without it. Some people find that their symptoms are still better after they've stopped taking it.

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