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Written By ,
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Dec 7, 2024 | 2:25 PM IST
VALRATE CR 200MG TABLET is used to treat arrhythmia (irregular heartbeat). It contains Dronedarone which works by blocking abnormal electrical signals in the heart and restoring normal heart rhythm. In some cases, this medicine may cause side effects such as slow heartbeat, diarrhoea, nausea and vomiting. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Prescription drug

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Prescription drug
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Manufacturer/Marketer

Ipca Laboratories Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About VALRATE CR 200MG TABLET

VALRATE CR 200MG TABLET belongs to a group of medications known as 'anti-arrhythmic' primarily used to treat arrhythmia (irregular heartbeat) in patients with paroxysmal (sudden attack) or persistent atrial fibrillation (irregular heartbeat due to poor blood flow). Besides this, VALRATE CR 200MG TABLET is also used to treat 'cardioversion' which is a medical procedure that changes the abnormal heartbeat to a normal rhythm. Arrhythmia is a problem associated with the rate of rhythm at which the heartbeats.

VALRATE CR 200MG TABLET contains 'Dronedarone' a Class III anti-arrhythmic drug that restores normal heart rhythm and reduces heart rate in atrial fibrillation. VALRATE CR 200MG TABLET blocks abnormal electrical signals in the heart. Also, it prevents ventricular fibrillation (a rapid contraction of heart muscle) and ventricular tachycardia (lower chambers of the heart ventricles that beat quickly than normal).

Take VALRATE CR 200MG TABLET as prescribed by your doctor. Your dose and duration of VALRATE CR 200MG TABLET will be advised by your doctor, depending upon your medical condition. In some cases, you may experience slow heartbeat, diarrhoea, nausea and vomiting. Most of these side effects of VALRATE CR 200MG TABLET do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.  

Please inform your doctor if you are using any prescription, non-prescription drugs, including vitamins and herbal products. Let your doctor know if you have any allergic reactions to VALRATE CR 200MG TABLET or any other medicines, before starting VALRATE CR 200MG TABLET. Inform your doctor if you have heart, kidney or liver problems and electrolyte imbalance. It is advised to consult a doctor if you are a pregnant or breastfeeding mother. VALRATE CR 200MG TABLET is not recommended for use during pregnancy. Do not stop taking VALRATE CR 200MG TABLET without consulting your doctor since it may worsen your condition and increase the risk of future heart problems. 

Uses of VALRATE CR 200MG TABLET

Treatment of Arrhythmia (irregular heartbeat).

Medicinal Benefits

VALRATE CR 200MG TABLET contains Dronedarone, a class III anti-arrhythmic drug. It treats arrhythmia (irregular heartbeat) in patients with paroxysmal (sudden attack) or persistent atrial fibrillation (irregular heartbeat due to poor blood flow). It blocks abnormal electrical signals in the heart and works by restoring normal heart rhythm. It also prevents ventricular fibrillation (a rapid contraction of heart muscle) and ventricular tachycardia (lower chambers of the heart (ventricles) beat quickly than normal). VALRATE CR 200MG TABLET is used in cardioversion, a medical procedure that changes the abnormal heartbeat to a normal rhythm.

Directions for Use

Tablet: Take it with or without food at regular intervals, as prescribed by the doctor. Do not crush, chew or break it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of VALRATE CR 200MG TABLET

  • Slow heartbeat
  • Diarrhoea
  • Increased liver enzymes
  • Nausea
  • Vomiting 
  • Abdominal pain
  • Fatigue

Drug Warnings

Brief your medical history to the doctor if you have any heart problems liver, kidney diseases and electrolyte imbalance (low potassium and magnesium) before starting VALRATE CR 200MG TABLET. VALRATE CR 200MG TABLET may affect QT prolongation (heart muscle takes longer than usual to recharge between beats) that can cause serious fast/irregular heartbeat. Hence it is advised to inform your doctor if you have heart-related problems like heart failure, slow heartbeat and a family history of heart diseases. VALRATE CR 200MG TABLET is contraindicated during pregnancy since it has harmful effects on the foetus. Consult your doctor before using VALRATE CR 200MG TABLET if you are a breastfeeding mother. Do not drive or operate machinery if you experience any side effects that affect your ability to concentrate and drive. Avoid consumption of alcohol with VALRATE CR 200MG TABLET as it may decrease the efficacy of VALRATE CR 200MG TABLET. VALRATE CR 200MG TABLET is not recommended in patients younger than 18 years of age.

Drug Interactions

Drug-Drug Interaction: VALRATE CR 200MG TABLET may interact with antibiotics (ketoconazole, itraconazole, voriconazole, clarithromycin, erythromycin, telithromycin), HIV drugs (lopinavir, ritonavir, rifampin), fits medicines (carbamazepine, phenobarbital, phenytoin), antidepressants (nefazodone, flibanserin), multiple sclerosis treating drugs (fingolimod), blood thinners (dabigatran) and heart-related drugs (digoxin).

Drug-Food Interaction: Avoid grapefruit and its products to prevent the occurrence of side effects of VALRATE CR 200MG TABLET.

Drug-Disease Interaction: People with heart problems, liver and kidney diseases, and electrolyte imbalance (low levels of potassium and magnesium) should consult the doctor before taking VALRATE CR 200MG TABLET. VALRATE CR 200MG TABLET is contraindicated in patients with class IV heart failure requiring hospitalization or referral to a specialized heart failure clinic. 

Drug-Drug Interactions Checker List

  • KETOCONAZOLE
  • ITRACONAZOLE
  • VORICONAZOLE
  • CLARITHROMYCIN
  • ERYTHROMYCIN
  • TELITHROMYCIN
  • LOPINAVIR
  • RITONAVIR
  • RIFAMPIN
  • CARBAMAZEPINE
  • PHENOBARBITAL
  • PHENYTOIN
  • NEFAZODONE
  • FLIBANSERIN
  • FINGOLIMOD
  • DABIGATRAN
  • DIGOXIN

Habit Forming

No

Diet & Lifestyle Advise

  • Keep your weight under control with BMI 19.5-24.9.
  • Opt for a diet rich in whole grains, fruits, veggies, and low-fat dairy products.
  • Limit sodium chloride intake (table salt) in your daily diet to 2300 mg per day or less than 1500 mg is ideal for most adults.
  • If you are taking alcohol, then only one serving for women and two servings for men is advisable.
  • Quitting smoking is the best strategy to lower the risk of heart disease.
  • Avoid chronic stress as it can raise your blood pressure. Try to enjoy and spent time with your loved ones to cope with stress and practice mindfulness techniques.
  • Try to include heart-healthy omega 3 fatty acid containing food drinks in your daily diet. You can also use low-fat cooking oil like olive oil, soybean oil, canola oil and coconut oil to lower your elevated blood pressure.

Special Advise

  • Keep a check on your daily blood pressure, and if you notice any fluctuations, please consult a doctor.
  • Regular monitoring of heart function with ECG or EKG is necessary.
  • Liver and kidney function tests are recommended to rule out any chances of kidney or liver impairment.
  • Regular examinations of your electrolytes like potassium and magnesium are recommended. Prolonged use may decrease the level of potassium and magnesium level in the body. 

Disease/Condition Glossary

Arrhythmia: It is a problem associated with the rate of rhythm at which the heart beats. Generally, in this condition, the heart beats too fast, too slow or with an irregular rate. It can lead to severe heart damage. A cardiac arrhythmia occurs when there are abnormal electrical signals in the heart. When the heart beats too fast, it is known as tachycardia, and if it is too slow, it is called bradycardia. Treatment of arrhythmia includes drugs, medical procedures, implantable devices and sometimes surgery.

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Alcohol

Caution

It is advised to limit alcohol intake when you are being treated with VALRATE CR 200MG TABLET.

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Pregnancy

Unsafe

VALRATE CR 200MG TABLET is a pregnancy category X drug, so it is not recommended and unsafe in pregnancy. It can affect and harm the developing baby. Please seek medical advice for more information.

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Breast Feeding

Caution

It is not known if VALRATE CR 200MG TABLET is excreted into the breast milk. Due to possible effects on the breastfed infant, VALRATE CR 200MG TABLET is not recommended for use if you are a nursing mother. Please consult your doctor for more information before taking VALRATE CR 200MG TABLET.

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Driving

Caution

VALRATE CR 200MG TABLET is possibly safe and does not affect your ability to drive. However, if you experience any symptoms that may affect your mental focus and ability to drive, do not drive or operate machinery until you feel better.

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Liver

Caution

Let your doctor know if you have any history of liver diseases before taking VALRATE CR 200MG TABLET. Your doctor will weigh the benefits and any potential risks before prescribing VALRATE CR 200MG TABLET.

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Kidney

Caution

Let your doctor know if you have any history of kidney diseases before taking VALRATE CR 200MG TABLET. Your doctor will weigh the benefits and any potential risks before prescribing VALRATE CR 200MG TABLET.

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Children

Unsafe

Safety and effectiveness of VALRATE CR 200MG TABLET have not been established in patients below 18 years of age.

Country of origin

India

Manufacturer/Marketer address

142 AB, Kandivli Industrial Estate, Kandivli (West), Mumbai - 400 067, Maharashtra
Other Info - VAL0053

FAQs

VALRATE CR 200MG TABLET is used to treat arrhythmia (irregular heartbeat) in patients with paroxysmal (sudden attack) or persistent atrial fibrillation (irregular heartbeat due to poor blood flow).
VALRATE CR 200MG TABLET contains Dronedarone that works as an antiarrhythmic by blocking abnormal electrical signals in the heart. Thus VALRATE CR 200MG TABLET helps to treat the uneven heartbeats and helps in normalising the heart rhythm.
Do not stop using VALRATE CR 200MG TABLET even if you feel better. It should be strictly used as advised by your doctor to avoid the recurrence of symptoms like irregular heartbeat and worsening of the disease.
VALRATE CR 200MG TABLET should be used with caution in cases of any allergic reactions, heart problems like heart failure, slow heartbeat, QT prolongation (heart muscle takes longer than usual to recharge between beats) in the ECG (electrocardiogram), liver, kidney diseases and electrolyte imbalance (low levels of potassium and magnesium).
Store VALRATE CR 200MG TABLET away from direct sunlight and at a temperature not exceeding 30°C. Keep this medicine out of sight and reach of children.
If you missed a dose, take VALRATE CR 200MG TABLET as soon as possible. However, if it is time for the next dose, skip the missed dose and go back to your regular dosing schedule. Do not double the dose.
VALRATE CR 200MG TABLET is used to treat arrhythmia (irregular heartbeat) in patients with paroxysmal (sudden onset) or persistent atrial fibrillation (irregular heartbeat caused by poor blood flow). Additionally, it is used in ‘cardioversion,' a medical procedure that restores an abnormal heartbeat to a normal rhythm.
Yes, VALRATE CR 200MG TABLET is safe if taken in dose and duration exactly as prescribed by the doctor.
Warning signals of liver toxicity caused by VALRATE CR 200MG TABLET may include dark urine, yellowing of the skin or eyes (jaundice), light-coloured stools, loss of appetite, nausea, vomiting, unusual tiredness, and pain in the upper right side of the abdomen. If you notice any of these symptoms, consult the doctor immediately.
VALRATE CR 200MG TABLET may cause optic neuropathy, the symptoms of optic neuropathy may include blurred vision, sudden vision loss, loss of peripheral vision, difficulty seeing in low light, and pain when moving the eye. If you experience any of these symptoms, consult the doctor immediately.
VALRATE CR 200MG TABLET should be taken orally with or without food at regular intervals. Swallow it as a whole with a glass of water. Do not chew, crush or break it.
The side effects of VALRATE CR 200MG TABLET include diarrhoea, slow heartbeat, nausea and vomiting. Consult the doctor if any of these side effects persist or worsen.

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