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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy

Valpex CR-300 Tablet is used to treat epilepsy/seizures/fits. Additionally, it is also used to treat manic episodes associated with bipolar disorder and to prevent migraine. It contains Divalproex sodium, which decreases the brain's excessive and abnormal nerve activity. Thereby helps in controlling seizures. It helps block the nerve transmission across the brain and provides a calming effect. Thereby, helps treat bipolar disorder. In some cases, it may cause common side effects, such as abdominal pain, back pain, constipation, diarrhoea, dizziness, nausea, increased appetite, and vomiting. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Manufacturer/Marketer :

Alkem Laboratories Ltd

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

Valpex CR-300 Tablet belongs to a group of medicines called anticonvulsants or anti-epileptics used to treat epilepsy/seizures/fits. Additionally, Valpex CR-300 Tablet is also used to treat manic episodes associated with bipolar disorder and to prevent migraine. Epilepsy is a sudden rush of electricity in the brain. In epilepsy, the brain's electrical rhythms become imbalanced, resulting in recurrent seizures.

Valpex CR-300 Tablet contains 'Divalproex sodium', which decreases the brain's excessive and abnormal nerve activity. Thereby helps in controlling seizures. Valpex CR-300 Tablet increases the amount of a chemical substance called GABA, this helps block the nerve transmission across the brain and provides a calming effect. Thereby helps treat bipolar disorder. 

Take Valpex CR-300 Tablet with or without food. You are advised to take Valpex CR-300 Tablet as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side effects, such as abdominal pain, back pain, constipation, diarrhoea, dizziness, nausea, increased appetite, and vomiting. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Please do not stop taking Valpex CR-300 Tablet without consulting your doctor to avoid worsening of seizures. Do not take Valpex CR-300 Tablet if you are pregnant, as it could cause serious birth defects. If you are of childbearing age, use effective contraception while taking Valpex CR-300 Tablet . Consult your doctor before taking Valpex CR-300 Tablet if you are breastfeeding. Avoid driving or operating machinery as Valpex CR-300 Tablet causes dizziness, and may affect thinking and motor skills. Avoid consuming alcohol along with Valpex CR-300 Tablet as it could lead to increased dizziness. Care should be taken while giving Valpex CR-300 Tablet to children below 2 years as there is a higher risk of liver intoxication during the first 6 months of treatment. Keep your doctor informed about your health condition and medicines to rule out any side effects.

Treatment of Epilepsy, bipolar disorder, migraine.
Tablet/Capsule: Swallow it as a whole with a glass of water; do not chew or crush the tablet/capsule.Oral solution: Take the prescribed dose by mouth using the measuring cup/dosing syringe/dropper provided by the pack; shake the pack well before each use.

Valpex CR-300 Tablet belongs to a group of medicines called anticonvulsants or anti-epileptics. Valpex CR-300 Tablet is used to treat epilepsy/seizures/fits. Additionally, Valpex CR-300 Tablet is also used to treat mood disorders and to prevent migraine headaches. Valpex CR-300 Tablet decreases the excessive and abnormal nerve activity in the brain. Thereby helps in controlling seizures. Valpex CR-300 Tablet treats mood disorder by increasing the amount of a chemical substance called GABA, this helps block the nerve transmission across the brain and provides a calming effect. Valpex CR-300 Tablet prevents migraine headaches by limiting the transmission of nerve pain. Valpex CR-300 Tablet is used alone or in combination to treat simple seizures, complex partial seizures and complex absence seizures. Valpex CR-300 Tablet is used in combination to treat multiple seizures, such as absence seizures.

Valpex CR-300 Tablet contains 'Divalproex sodium', which decreases the brain's excessive and abnormal nerve activity. Thereby helps in controlling seizures. Valpex CR-300 Tablet increases the amount of a chemical substance called GABA, this helps block the nerve transmission across the brain and provides a calming effect. Thereby helps treat bipolar disorder.
Store in a cool and dry place away from sunlight
  • Abdominal pain
  • Back pain
  • Constipation
  • Diarrhoea
  • Dizziness
  • Nausea
  • Increased appetite
  • Vomiting
  • Vision problems
  • Weight changes
  • Problems with walking or coordination
Do not take more than the prescribed dose of Valpex CR-300 Tablet as it may cause overdose. The symptoms of overdose include heart block, excess sleepiness and deep coma. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Do not take Valpex CR-300 Tablet if you are allergic to any of its contents, have/ had liver problems or urea cycle disorders. Inform your doctor before taking Valpex CR-300 Tablet if you have pancreatitis, blood problems or multi-organ hypersensitivity. Consult your doctor immediately if you experience suicidal tendency while taking Valpex CR-300 Tablet . Valpex CR-300 Tablet may cause thrombocytopenia (low blood platelets), hyperammonemia (high levels of ammonia in the blood), hypothermia (low body temperature) and liver problems. Please do not stop taking Valpex CR-300 Tablet without consulting your doctor to avoid worsening of seizures. Do not take Valpex CR-300 Tablet if you are pregnant as it could cause serious birth defects. If you are of child-bearing age, use effective contraception while taking Valpex CR-300 Tablet . Consult your doctor before taking Valpex CR-300 Tablet if you are breastfeeding. Avoid driving or operating machinery as Valpex CR-300 Tablet causes dizziness and may affect thinking and motor skills. Avoid consuming alcohol along with Valpex CR-300 Tablet as it could lead to increased dizziness. Care should be taken while giving Valpex CR-300 Tablet to children below 2years as there is a higher risk of liver intoxication during the first 6months of treatment.

verifiedApollotooltip
Sodium ValproateSodium phenylbutyrate
Critical
Sodium ValproateDoripenem
Severe

Drug-Drug Interactions

Sodium ValproateSodium phenylbutyrate
Critical
How does the drug interact with Valpex CR-300 Tablet 10's:
Combining Sodium phenylbutyrate and Valpex CR-300 Tablet 10's can increase ammonia levels in the blood.

How to manage the interaction:
Taking Sodium phenylbutyrate with Valpex CR-300 Tablet 10's is not recommended, but it can be taken if prescribed by a doctor. If you experience any symptoms like sudden dizziness, lightheadedness, fainting, headache, shortness of breath, nausea, vomiting, chest pain or tightness, rapid heartbeat, or memory loss, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
Sodium ValproateDoripenem
Severe
How does the drug interact with Valpex CR-300 Tablet 10's:
Co-administration of Valpex CR-300 Tablet 10's with doripenem can reduce the blood levels of valproic acid.

How to manage the interaction:
Co-administration of Doripenam and Valpex CR-300 Tablet 10's can lead to an interaction, it can be taken if advised by your doctor. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, involuntary muscle movements, or memory loss, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
Sodium ValproateMeropenem
Severe
How does the drug interact with Valpex CR-300 Tablet 10's:
Co-administration of Meropenam and Valpex CR-300 Tablet 10's together can reduce the effect of Valpex CR-300 Tablet 10's.

How to manage the interaction:
Co-administration of Meropenam and Valpex CR-300 Tablet 10's can lead to an interaction, but it can be taken if your doctor advises. However, if you experience any unusual symptoms, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
Sodium ValproateTeriflunomide
Severe
How does the drug interact with Valpex CR-300 Tablet 10's:
Co-administration of Teriflunomide and Valpex CR-300 Tablet 10's can increase the risk of causing liver problems.

How to manage the interaction:
Co-administration of Teriflunomide and Valpex CR-300 Tablet 10's can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark-colored urine, light-colored stools, and yellowing of the skin or eyes. Avoid alcohol while taking these medications, and consult your doctor immediately. Do not discontinue any medications without consulting your doctor.
Sodium ValproateLeflunomide
Severe
How does the drug interact with Valpex CR-300 Tablet 10's:
Co-administration of Leflunomide and Valpex CR-300 Tablet 10's can increase the risk of causing liver problems.

How to manage the interaction:
Co-administration of Leflunomide and Valpex CR-300 Tablet 10's can lead to an interaction, they can be taken together if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, or yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Sodium ValproateErtapenem
Severe
How does the drug interact with Valpex CR-300 Tablet 10's:
The combined use of Ertapenem and Valpex CR-300 Tablet 10's can reduce the blood levels of valproic acid.

How to manage the interaction:
Co-administration of Ertapenem and Valpex CR-300 Tablet 10's can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like loss of seizure control or changes in behavior, consult your doctor immediately. Do not discontinue any medications without consulting the doctor.
Sodium ValproateVorinostat
Severe
How does the drug interact with Valpex CR-300 Tablet 10's:
Co-administration of Vorinostat with Valpex CR-300 Tablet 10's can increase the risk of unusual bleeding.

How to manage the interaction:
Co-administration of Vorinostat and Valpex CR-300 Tablet 10's can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, consult your doctor immediately. Do not discontinue any medications without consulting your doctor.
Sodium ValproateBuprenorphine
Severe
How does the drug interact with Valpex CR-300 Tablet 10's:
Using buprenorphine together with Valpex CR-300 Tablet 10's may increase the risk of severe side effects, including respiratory problems and loss of consciousness.

How to manage the interaction:
Although the administration of buprenorphine alongside Valpex CR-300 Tablet 10's can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Sodium ValproateKetamine
Severe
How does the drug interact with Valpex CR-300 Tablet 10's:
Co-administration of Ketamine and Valpex CR-300 Tablet 10's can increase side effects and cause respiratory depression.

How to manage the interaction:
Co-administration of Ketamine and Valpex CR-300 Tablet 10's can lead to an interaction, but it can be taken if your doctor advises. However, consult your doctor immediately if you experience any symptoms like dizziness, drowsiness, confusion, difficulty concentrating, excessive sedation, impaired thinking, judgment, and motor coordination. Avoid driving or operating hazardous machinery until you know how these medications affect you. Do not discontinue any medications without consulting the doctor.
Sodium ValproateLithium
Severe
How does the drug interact with Valpex CR-300 Tablet 10's:
Co-administration of Lithium with Valpex CR-300 Tablet 10's can increase the risk irregular heart rhythm.

How to manage the interaction:
Co-administration of Lithium and Valpex CR-300 Tablet 10's can lead to an interaction, but it can be taken if advised by your doctor. However, consult your doctor immediately if you experience any symptoms like dizziness, drowsiness, confusion, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, and difficulty concentrating. Do not discontinue any medications without consulting a doctor.
verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

  • A ketogenic diet (low in carbohydrates and high in fats) is recommended for children with epilepsy. This diet helps in utilising fat instead of glucose for the generation of energy.

  • Atkins diet (high fay and controlled carbohydrates) is recommended for adolescents and adults.

  • Exercising regularly helps in maintaining weight and improving overall health. 

  • Rest well, get plenty of sleep.

  • Avoid smoking and alcohol consumption.

  • Meditation and yoga can help lower the stress, decrease pain sensitivity and improves coping skills.

  • Have a seizure response plan, help those around you know what to do.

  • Prepare your living area, small changes may reduce the risk of physical injury during a seizure.

  • Understand what triggers seizures and try reducing or avoiding them.

  • Please pay attention to overall health as it can help in reducing seizure activity.

  • Install an alarm or emergency device to get assistance during a seizure attack.

No
ANTICONVULSANT
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Caution

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FAQs

Valpex CR-300 Tablet is used to treat epilepsy/seizures/fits. Additionally, it is also used to treat manic episodes associated with bipolar disorder and to prevent migraine.
Valpex CR-300 Tablet decreases the excessive and abnormal nerve activity in the brain. Thereby helps in controlling seizures.
Valpex CR-300 Tablet helps to treat manic episodes associated with bipolar disorder by increasing the amount of a chemical substance called GABA, this helps in blocking the nerve transmission across the brain and provides a calming effect.
Valpex CR-300 Tablet limits the transmission of nerve pain, thereby prevents migraine headache. Migraine is a neurological condition which is characterized by intense headaches.
Do not discontinue Valpex CR-300 Tablet without consulting your doctor. To treat your condition effectually continue taking Valpex CR-300 Tablet for as long as prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking Valpex CR-300 Tablet , your doctor will reduce the dose gradually to avoid worsening of seizures.
Valpex CR-300 Tablet may cause weight gain due to an increase in appetite. Maintain a healthy weight by following a healthy diet and exercising regularly.
Use an effective method of contraception during the treatment with Valpex CR-300 Tablet . Avoid getting pregnant while taking Valpex CR-300 Tablet as it could lead to serious birth defects. Do not stop taking Valpex CR-300 Tablet and consult your doctor immediately if you become pregnant.
Valpex CR-300 Tablet may cause thrombocytopenia (low levels of platelets). This might increase the risk of bleeding and bruising. Be cautious while using sharp objects. Consult your doctor if you notice unexplained bleeding or bruising. Regular monitoring of blood count is advised while taking Valpex CR-300 Tablet .
Topiramate (anticonvulsant) should not be taken along with Valpex CR-300 Tablet as it may cause hyperammonemia (excess ammonia in the blood), hypothermia (low body temperature) and liver problems.
It's crucial to consult with your doctor before discontinuing Valpex CR-300 Tablet . Abruptly stopping this medication can lead to severe consequences, mainly if it's prescribed to treat conditions like epilepsy.
Valpex CR-300 Tablet is also used to treat mood disorders. It treats mood disorders by increasing the amount of a chemical substance called GABA, which helps block nerve transmission across the brain and provides a calming effect.
Valpex CR-300 Tablet can indeed make you sleepy. This is a common side effect of the medication. If you're experiencing excessive drowsiness, you must talk to your doctor.
Yes, Valpex CR-300 Tablet can cause hair loss as a side effect. While this isn't a common side effect, it can occur in some people. If you notice significant hair loss while taking Valpex CR-300 Tablet , it's essential to consult with your doctor.
Yes, Valpex CR-300 Tablet can potentially damage your liver. While this is a rare side effect, being aware of the risk is essential. Signs of liver damage may include yellowing of the skin or eyes or jaundice, dark urine, abdominal pain, light-coloured stools, nausea and vomiting. If you experience any of these symptoms while taking Valpex CR-300 Tablet , seeking medical attention is crucial.
Avoid consumption of alcohol while taking Valpex CR-300 Tablet as it may cause increased dizziness.
If you experience abdominal pain, nausea, and anorexia while taking Valpex CR-300 Tablet , it's essential to contact your doctor immediately. These symptoms can be signs of a severe side effect, such as liver damage.
Overdose of Valpex CR-300 Tablet can be a severe medical emergency. If you or someone you know has taken an overdose of Valpex CR-300 Tablet , it's crucial to seek immediate medical attention.
India
Alkem Laboratories Limited, Devashish Building, Alkem House, Senapati Bapat Road, Lower Parel, Mumbai - 400 013.
Other Info - VAL0074

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