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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Valparin Chrono 200 mg Tablet is used to treat epilepsy/seizures/fits. Additionally, it is also used to treat mood disorders and migraine. It contains Sodium valproate and Valproic acid, which works by decreasing the excessive and abnormal nerve activity in the brain. Thereby, it helps in controlling seizures. It blocks the nerve transmission across the brain and provides a calming effect. In some cases, it may cause common side effects such as headache, sleepiness, drowsiness, impaired coordination, apathy (lack of interest), irregular periods and weight gain. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Manufacturer/Marketer :

Sanofi India Ltd

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Valparin Chrono 200 mg Tablet

Valparin Chrono 200 mg Tablet belongs to a group of medicines called 'anticonvulsants' or 'anti-epileptics' primarily used to treat epilepsy/seizures/fits. Additionally, Valparin Chrono 200 mg Tablet is also used to treat mood disorders and migraine. Epilepsy is a sudden rush of electricity in the brain. In patients with seizures, the typical brain electrical pattern is disrupted by sudden bursts of electrical impulses that affect an individual's consciousness, movements or sensations.
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Valparin Chrono 200 mg Tablet is a combination of two drugs, namely: Sodium valproate and Valproic acid. Valparin Chrono 200 mg Tablet works by decreasing the excessive and abnormal nerve activity in the brain. Thereby helps in controlling seizures. Valparin Chrono 200 mg Tablet increases the amount of a chemical substance called GABA, this helps block the nerve transmission across the brain and provides a calming effect.
 
You are advised to take Valparin Chrono 200 mg Tablet for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side effects such as headache, sleepiness, drowsiness, impaired coordination, apathy (lack of interest), irregular periods and weight gain. Talk to your doctor if you experience these side effects persistently.
 
Do not take Valparin Chrono 200 mg Tablet if you are pregnant, as it could cause serious congenital disabilities. If you are of childbearing age, use effective contraception while taking Valparin Chrono 200 mg Tablet . Consult your doctor before taking Valparin Chrono 200 mg Tablet if you are breastfeeding. Valparin Chrono 200 mg Tablet causes drowsiness and dizziness, so avoid driving unless you are alert. Avoid consuming alcohol along with Valparin Chrono 200 mg Tablet as it could lead to an increased risk of seizures. Care should be taken while giving Valparin Chrono 200 mg Tablet to children below 3 years as there is a higher risk of liver intoxication during the first 6 months of treatment.

Uses of Valparin Chrono 200 mg Tablet

Treatment of Epilepsy, Mood disorder, Migraine.

Directions for Use

Take Valparin Chrono 200 mg Tablet with or 1 hour prior to food. Swallow Valparin Chrono 200 mg Tablet a whole with a glass of water; do not chew or break it.

Medicinal Benefits

Valparin Chrono 200 mg Tablet is a combination of two drugs, namely: Sodium valproate and Valproic acid. Valparin Chrono 200 mg Tablet is used to treat epilepsy/seizures/fits, mood disorders and to prevent migraine headaches. Valparin Chrono 200 mg Tablet decreases the excessive and abnormal nerve activity in the brain, thereby controlling seizures. Valparin Chrono 200 mg Tablet is used to treat certain forms of epilepsy, such as petit mal epilepsy (short-term unconsciousness due to a disorder in the brain), myoclonic seizures (sudden muscle contractions) and grand mal epilepsy (severe muscle contractions which lead to unconsciousness). Valparin Chrono 200 mg Tablet may also be used to treat epilepsy, which does not sufficiently respond to other anticonvulsant drugs, such as epilepsy, which is not associated with movements and epilepsy, with symptoms affecting perception and deliberate movements. Valparin Chrono 200 mg Tablet is used to treat both partial seizures (affects only a part of the brain) and generalised seizures (affects the entire brain).

How Valparin Chrono 200 mg Tablet Works

Valparin Chrono 200 mg Tablet is a combination of two drugs, namely: Sodium valproate and Valproic acid. Valparin Chrono 200 mg Tablet works by decreasing the excessive and abnormal nerve activity in the brain. Thereby helps in controlling seizures. Valparin Chrono 200 mg Tablet increases the amount of a chemical substance called GABA, this helps block the nerve transmission across the brain and provides a calming effect.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Valparin Chrono 200 mg Tablet

  • Headache
  • Nausea
  • Vomiting
  • Diarrhoea
  • Sleepiness
  • Drowsiness
  • Impaired coordination
  • Apathy (lack of interest)
  • Hair loss
  • Irregular periods
  • Weight gain

What if I have taken an overdose of Valparin Chrono 200 mg Tablet

Do not take more than the prescribed dose of Valparin Chrono 200 mg Tablet as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

Do not take Valparin Chrono 200 mg Tablet if you are allergic to any of its contents, if you have/ had liver problems, porphyria (blood disorder) or if you are susceptible to bleeding. Inform your doctor if you have inflammation-like diseases, bone marrow damage or kidney problems. Talk to your doctor if you experience weakness, loss of appetite, lack of interest, recurrence or worsening of seizures, prolonged bleeding or abdominal pain while taking Valparin Chrono 200 mg Tablet . Consult your doctor immediately if you experience suicidal tendencies while taking Valparin Chrono 200 mg Tablet . Please do not stop taking Valparin Chrono 200 mg Tablet without consulting your doctor to avoid the worsening of seizures. Do not take Valparin Chrono 200 mg Tablet if you are pregnant, as it could cause serious birth defects. If you are of child-bearing age, use effective contraception while taking Valparin Chrono 200 mg Tablet . Consult your doctor before taking Valparin Chrono 200 mg Tablet if you are breastfeeding. Valparin Chrono 200 mg Tablet causes drowsiness and dizziness, so avoid driving unless you are alert. Avoid consuming alcohol along with Valparin Chrono 200 mg Tablet as it could lead to increased risk of seizures. Care should be taken while giving Valparin Chrono 200 mg Tablet to children below 3 years as there is a higher risk of liver intoxication during the first 6 months of treatment.

Drug-Drug Interactions

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Sodium ValproateSodium phenylbutyrate
Critical
Sodium ValproateLeflunomide
Severe

Drug-Drug Interactions

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Sodium ValproateSodium phenylbutyrate
Critical
How does the drug interact with Valparin Chrono 200 Tablet 15's:
Combining Sodium phenylbutyrate and Valparin Chrono 200 Tablet 15's can increase ammonia levels in the blood.

How to manage the interaction:
Taking Sodium phenylbutyrate with Valparin Chrono 200 Tablet 15's is not recommended, but it can be taken if prescribed by a doctor. If you experience any symptoms like sudden dizziness, lightheadedness, fainting, headache, shortness of breath, nausea, vomiting, chest pain or tightness, rapid heartbeat, or memory loss, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
Sodium ValproateLeflunomide
Severe
How does the drug interact with Valparin Chrono 200 Tablet 15's:
Co-administration of Leflunomide and Valparin Chrono 200 Tablet 15's can increase the risk of causing liver problems.

How to manage the interaction:
Co-administration of Leflunomide and Valparin Chrono 200 Tablet 15's can lead to an interaction, they can be taken together if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, or yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Sodium ValproateLithium
Severe
How does the drug interact with Valparin Chrono 200 Tablet 15's:
Co-administration of Lithium with Valparin Chrono 200 Tablet 15's can increase the risk irregular heart rhythm.

How to manage the interaction:
Co-administration of Lithium and Valparin Chrono 200 Tablet 15's can lead to an interaction, but it can be taken if advised by your doctor. However, consult your doctor immediately if you experience any symptoms like dizziness, drowsiness, confusion, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, and difficulty concentrating. Do not discontinue any medications without consulting a doctor.
Sodium ValproateErtapenem
Severe
How does the drug interact with Valparin Chrono 200 Tablet 15's:
The combined use of Ertapenem and Valparin Chrono 200 Tablet 15's can reduce the blood levels of valproic acid.

How to manage the interaction:
Co-administration of Ertapenem and Valparin Chrono 200 Tablet 15's can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like loss of seizure control or changes in behavior, consult your doctor immediately. Do not discontinue any medications without consulting the doctor.
Sodium ValproateVorinostat
Severe
How does the drug interact with Valparin Chrono 200 Tablet 15's:
Co-administration of Vorinostat with Valparin Chrono 200 Tablet 15's can increase the risk of unusual bleeding.

How to manage the interaction:
Co-administration of Vorinostat and Valparin Chrono 200 Tablet 15's can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, consult your doctor immediately. Do not discontinue any medications without consulting your doctor.
Sodium ValproateDoripenem
Severe
How does the drug interact with Valparin Chrono 200 Tablet 15's:
Co-administration of Valparin Chrono 200 Tablet 15's with doripenem can reduce the blood levels of valproic acid.

How to manage the interaction:
Co-administration of Doripenam and Valparin Chrono 200 Tablet 15's can lead to an interaction, it can be taken if advised by your doctor. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, involuntary muscle movements, or memory loss, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
Sodium ValproateMeropenem
Severe
How does the drug interact with Valparin Chrono 200 Tablet 15's:
Co-administration of Meropenam and Valparin Chrono 200 Tablet 15's together can reduce the effect of Valparin Chrono 200 Tablet 15's.

How to manage the interaction:
Co-administration of Meropenam and Valparin Chrono 200 Tablet 15's can lead to an interaction, but it can be taken if your doctor advises. However, if you experience any unusual symptoms, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
Sodium ValproateKetamine
Severe
How does the drug interact with Valparin Chrono 200 Tablet 15's:
Co-administration of Ketamine and Valparin Chrono 200 Tablet 15's can increase side effects and cause respiratory depression.

How to manage the interaction:
Co-administration of Ketamine and Valparin Chrono 200 Tablet 15's can lead to an interaction, but it can be taken if your doctor advises. However, consult your doctor immediately if you experience any symptoms like dizziness, drowsiness, confusion, difficulty concentrating, excessive sedation, impaired thinking, judgment, and motor coordination. Avoid driving or operating hazardous machinery until you know how these medications affect you. Do not discontinue any medications without consulting the doctor.
Sodium ValproateBuprenorphine
Severe
How does the drug interact with Valparin Chrono 200 Tablet 15's:
Using buprenorphine together with Valparin Chrono 200 Tablet 15's may increase the risk of severe side effects, including respiratory problems and loss of consciousness.

How to manage the interaction:
Although the administration of buprenorphine alongside Valparin Chrono 200 Tablet 15's can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Sodium ValproateTeriflunomide
Severe
How does the drug interact with Valparin Chrono 200 Tablet 15's:
Co-administration of Teriflunomide and Valparin Chrono 200 Tablet 15's can increase the risk of causing liver problems.

How to manage the interaction:
Co-administration of Teriflunomide and Valparin Chrono 200 Tablet 15's can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark-colored urine, light-colored stools, and yellowing of the skin or eyes. Avoid alcohol while taking these medications, and consult your doctor immediately. Do not discontinue any medications without consulting your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • A ketogenic diet (low in carbohydrates and high in fats) is recommended for children with epilepsy. This diet helps in utilising fat instead of glucose for the generation of energy.

  • Atkins diet (high fat and controlled carbohydrates) is recommended for adolescents and adults.

  • Exercising regularly helps in maintaining weight and improving overall health. 

  • Rest well, and get plenty of sleep.

  • Avoid smoking and alcohol consumption.

  • Meditation and yoga can help lower stress, decrease pain sensitivity and improves coping skills.

  • Have a seizure response plan; this helps those around you know what to do.

  • Prepare your living area; small changes may help in reducing the risk of physical injury during a seizure.

  • Understand what triggers seizures and try reducing or avoiding them.

  • Please pay attention to overall health as it can help in reducing seizure activity.

  • Install an alarm or emergency device to get assistance during a seizure attack.

Habit Forming

No

Therapeutic Class

ANTICONVULSANT

Valparin Chrono 200 mg Tablet Substitute

Substitutes safety advice
  • Alporate-200 Tablet 15's

    by AYUR

    3.60per tablet
  • Valparin Chrono 200 Tablet 10's

    6.53per tablet
  • T-Val CR 200 mg Tablet 10's

    5.85per tablet
  • Zyval CR 200 Tablet

    4.86per tablet
  • Leps 133mg/58mg Tablet CR

    2.39per tablet
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Alcohol

Unsafe

Avoid consumption of alcohol while taking Valparin Chrono 200 mg Tablet as it may increase the risk of seizures.

bannner image

Pregnancy

Unsafe

Valparin Chrono 200 mg Tablet belongs to pregnancy category D. Avoid taking Valparin Chrono 200 mg Tablet if you are pregnant unless prescribed by a doctor, as it could lead to serious birth defects.

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Breast Feeding

Caution

Valparin Chrono 200 mg Tablet may pass into breastmilk. Consult your doctor before taking Valparin Chrono 200 mg Tablet if you are breastfeeding.

bannner image

Driving

Unsafe

Valparin Chrono 200 mg Tablet causes dizziness, sleepiness and drowsiness. Do not drive or operate machinery unless you are alert.

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Liver

Unsafe

Valparin Chrono 200 mg Tablet should not be used if you have liver problems or your family has a history of liver problems. Please consult your doctor if you have any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

bannner image

Children

Caution

Valparin Chrono 200 mg Tablet can be given to children if prescribed by the doctor. The dose will be adjusted by the doctor depending upon the child's body weight.

FAQs

Valparin Chrono 200 mg Tablet is primarily used to treat epilepsy/seizures/fits. It is also used to treat mood disorders and migraine.
Valparin Chrono 200 mg Tablet decreases the excessive and abnormal nerve activity in the brain. Valparin Chrono 200 mg Tablet increases the amount of a chemical substance called GABA, this helps in blocking the nerve transmission across the brain and provides a calming effect. Thereby helps in controlling seizures.
Do not discontinue Valparin Chrono 200 mg Tablet without consulting your doctor. To treat your condition effectually, continue taking Valparin Chrono 200 mg Tablet for as long as prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking Valparin Chrono 200 mg Tablet ; your doctor will reduce the dose gradually to avoid worsening of seizures.
Valparin Chrono 200 mg Tablet may cause thrombocytopenia (low levels of platelets). This might increase the risk of bleeding and bruising. Be cautious while using sharp objects. Consult your doctor if you notice unexplained bleeding or bruising.
Valparin Chrono 200 mg Tablet may cause weight gain due to an increase in appetite. Maintain a healthy weight by following a proper diet and exercising regularly.
Valparin Chrono 200 mg Tablet may increase the effect of aspirin when taken together. Please consult your doctor before taking Valparin Chrono 200 mg Tablet with aspirin to avoid unpleasant side-effects. Valparin Chrono 200 mg Tablet and aspirin should not be given together to children below 3 years as it could lead to liver intoxication.
Valparin Chrono 200 mg Tablet contains sodium valproate and valproic acid as the active ingredients. It is used for the treatment of all types of epilepsy.
Take Valparin Chrono 200 mg Tablet with or after food as advised by your doctor.
You are recommended to avoid consumption of alcohol while taking Valparin Chrono 200 mg Tablet as it may increase the risk of seizures.
No, Valparin Chrono 200 mg Tablet does not cause addiction. However, it should be taken as per dose and duration prescribed by your doctor. Avoid self-medication as it may have severe unwanted effects.
Valparin Chrono 200 mg Tablet does not cure epilepsy, it only prevents the seizures from occurring. Therefore, you may need to continue taking it for years. If you experience any problems while taking Valparin Chrono 200 mg Tablet , please consult your doctor.
You are recommended not to stop taking Valparin Chrono 200 mg Tablet suddenly as it may increase the chances of recurrence of seizures. Therefore, it should be discontinued gradually. If you feel the need to stop taking Valparin Chrono 200 mg Tablet , always consult your doctor.
Yes, Valparin Chrono 200 mg Tablet may cause weight gain. To control your weight, you should eat a healthy balanced diet and exercise regularly. If you have any other concerns, consult your doctor.
Yes, Valparin Chrono 200 mg Tablet has no influence on the working of birth control pills. However, contraceptives (birth control pills) may interfere with the working of Valparin Chrono 200 mg Tablet and seizures may occur. Thus, it is essential to inform your doctor if you are using birth control pills. Your doctor will monitor your response to the treatment and Valparin Chrono 200 mg Tablet levels in your blood.
Long term use of Valparin Chrono 200 mg Tablet is safe for large number of patients. Rarely, using Valparin Chrono 200 mg Tablet for long term may weaken your bones, thereby increasing their chances of breaking easily (osteopenia and osteoporosis). Get regular check-ups done for bone health if you are taking Valparin Chrono 200 mg Tablet for a prolonged time.
Valparin Chrono 200 mg Tablet may cause change of hair colour, thinning of hair, and even hair loss. If you have any concerns, discuss with your doctor if it is possible to reduce the dose of Valparin Chrono 200 mg Tablet . Your hair may regrow after either switching to a different medicine or reducing your dose.
Valparin Chrono 200 mg Tablet may cause side effects such as nausea, diarrhoea, hair loss, weight gain, headache and irregular periods. If these side effects persist or worsen, please consult your doctor.
You are recommended to avoid taking Valparin Chrono 200 mg Tablet if you have known hypersensitivity to valproic acid, have liver disease, or are pregnant. It should be used with caution in kidney impairment patients.
Valparin Chrono 200 mg Tablet overdose can cause serious symptoms such as metabolic acidosis and deep coma. If you suspect you have taken overdose of Valparin Chrono 200 mg Tablet , seek medical help immediately.

Country of origin

India

Manufacturer/Marketer address

CT Survey No.117-B, L&T Business Park, Saki Vihar Road, Powai, Mumbai 400072.
Other Info - VAL0457

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