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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Valfect H 80 Tablet is used to treat high blood pressure. It contains Valsartan and hydrochlorothiazide which work by relaxing and widening the narrowed blood vessels and removing extra water/fluid from the body. In some cases, this medicine may cause side effects such as nausea, diarrhoea, taste change, dizziness, upset stomach, fatigue, and headache. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Manufacturer/Marketer :

Astra Zeneca Pharma India Ltd

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Valfect H 80 Tablet

Valfect H 80 Tablet is an 'anti-hypertensives' medication primarily used for lowering high blood pressure (hypertension) by removing extra fluid (electrolytes) from the body. High blood pressure is a chronic condition in which the blood's force against the artery wall is high. As a result, it increases the risk of heart-related diseases like heart attack, heart failure, stroke, irregular heartbeat, and other complications.

Valfect H 80 Tablet is a combination of two medicines, namely Valsartan and hydrochlorothiazide. Valsartan is a blood pressure-lowering medicine that blocks the hormone angiotensin, thereby relaxing and widening the narrowed blood vessels. This allows the blood to flow more smoothly in the blood vessels, and the heart can pump more efficiently. On the other hand, Hydrochlorothiazide is a diuretic or water pill that works by removing extra water/fluid and certain electrolyte overload from the body. Together, Valfect H 80 Tablet lowers the fluid overload, raises blood pressure, improves blood flow, and reduces the future risk of a heart attack and stroke.

Take Valfect H 80 Tablet as prescribed by your doctor. You are advised to take Valfect H 80 Tablet for as long as your doctor has prescribed it for you, depending on your medical conditions. You may experience nausea, diarrhoea, taste change, dizziness, upset stomach, decreased blood pressure, fatigue, headache, increased blood lipid level, increased blood uric acid, electrolyte imbalance, and glucose intolerance. Most of these side effects of Valfect H 80 Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Valfect H 80 Tablet should not be taken if you are known to be allergic to Valfect H 80 Tablet or any other medicines. Try not to stop taking this medicine of your own. Let your doctor know about this, as it may cause a rise in blood pressure and increase heart disease and stroke risk. Do not use potassium supplements or salt substitutes unless the doctor has told you. This Valfect H 80 Tablet should not be used for children as the safety and efficacy of Valfect H 80 Tablet in children have not been established. You are recommended not to consume alcohol and Valfect H 80 Tablet to avoid unpleasant side effects like drowsiness, dizziness, and liver damage. Drive with caution, Valfect H 80 Tablet usually causes drowsiness and affects driving ability.

Uses of Valfect H 80 Tablet

Treatment of Hypertension (high blood pressure)

Directions for Use

Swallow Valfect H 80 Tablet as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Valfect H 80 Tablet is primarily used to reduce high blood pressure. It is a combination of two medicines, namely: Valsartan and Hydrochlorothiazide. Valsartan is a blood pressure-lowering medicine that blocks the hormone angiotensin, thereby relaxing and widening the narrowed blood vessels. This allows the blood to flow more smoothly in the blood vessels, and the heart can pump more efficiently. On the other hand, Hydrochlorothiazide is a diuretic or water pill that works by removing extra water/fluid and certain electrolytes overload from the body. Together, Valfect H 80 Tablet lowers the fluid overload, raised blood pressure, improves blood flow, and reduces the future risk of a heart attack and stroke.

How Valfect H 80 Tablet Works

Valfect H 80 Tablet is a combination of two medicines, namely Valsartan and hydrochlorothiazide. Valsartan is a blood pressure-lowering medicine that blocks the hormone angiotensin, thereby relaxing and widening the narrowed blood vessels. This allows the blood to flow more smoothly in the blood vessels, and the heart can pump more efficiently. On the other hand, Hydrochlorothiazide is a diuretic or water pill that works by removing extra water/fluid and certain electrolyte overload from the body. Together, Valfect H 80 Tablet lowers the fluid overload, raises blood pressure, improves blood flow, and reduces the future risk of a heart attack and stroke.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Valfect H 80 Tablet

  • Nausea
  • Diarrhea
  • Taste change
  • Dizziness
  • Upset stomach
  • Decreased blood pressure
  • Fatigue
  • Headache
  • Increased blood lipid level
  • Increased blood uric acid
  • Electrolyte imbalance
  • Glucose intolerance.

What if I have taken an overdose of Valfect H 80 Tablet

Take Valfect H 80 Tablet only as prescribed by the doctor. Avoid exceeding the recommended dose as it could lead to an overdose. Symptoms of overdose may include dizziness and fainting. If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

Before taking Valfect H 80 Tablet inform your doctor if you have liver disease, kidney disease, gout (inflammation and pain in joints), loss of water and minerals from the body, and skin cancer. If you have diarrhea, vomiting or sweating, immediately inform your doctor as it may cause serious loss of body water and risk of lightheadedness (feeling of dizziness and faintness). Valfect H 80 Tablet may affect the blood sugar, inform your doctor if you have diabetes and regularly monitor your blood sugar level. This Valfect H 80 Tablet may increase skin cancer risk, thus avoiding going in the sun and using sunscreen, and wearing protective cloth when you are going out. Do not use potassium supplements or salt substitutes unless the doctor has told you. This Valfect H 80 Tablet should not be used for children as the safety and efficacy of Valfect H 80 Tablet in children have not been established. You are recommended not to consume alcohol and Valfect H 80 Tablet to avoid unpleasant side effects like drowsiness, dizziness, and liver damage. Drive with caution, Valfect H 80 Tablet usually causes drowsiness and affects driving ability.

Drug-Drug Interactions

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ValsartanAliskiren
Critical
HydrochlorothiazideCisapride
Critical

Drug-Drug Interactions

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ValsartanAliskiren
Critical
How does the drug interact with Valfect H 80 Tablet 10's:
Using Aliskiren together with Valfect H 80 Tablet 10's may increase the risk of serious side effects (kidney problems, low blood pressure, or high potassium levels).

How to manage the interaction:
Taking Valfect H 80 Tablet 10's with Aliskiren is not advised as it can result in an interaction, it can be taken if a doctor has advised it. You should seek medical attention if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, a weak pulse, or a slow or irregular heartbeat. Do not discontinue any medications without a doctor's advice.
HydrochlorothiazideCisapride
Critical
How does the drug interact with Valfect H 80 Tablet 10's:
Taking Cisapride and Valfect H 80 Tablet 10's can increase the risk of an irregular heart rhythm which can be severe. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Combining Cisapride and Valfect H 80 Tablet 10's together is generally avoided as it can possibly result in an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like dizziness, lightheadedness, fainting, or fast or pounding heartbeats, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
HydrochlorothiazideDofetilide
Critical
How does the drug interact with Valfect H 80 Tablet 10's:
Taking Dofetilide and Valfect H 80 Tablet 10's can increase the risk of an irregular heart rhythm which can be severe. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Combining Dofetilide and Valfect H 80 Tablet 10's together is not recommended as it can possibly result in an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
ValsartanSpironolactone
Severe
How does the drug interact with Valfect H 80 Tablet 10's:
Using spironolactone together with Valfect H 80 Tablet 10's may increase potassium levels in the blood.

How to manage the interaction:
Although taking spironolactone and Valfect H 80 Tablet 10's together can result in an interaction, it can be taken if a doctor has prescribed it. However, consult a doctor immediately if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, a weak pulse, or a slow or irregular heartbeat. Do not stop using any medications without consulting a doctor.
ValsartanEnalapril
Severe
How does the drug interact with Valfect H 80 Tablet 10's:
Combine use of Enalapril and Valfect H 80 Tablet 10's can increase the effect of Valfect H 80 Tablet 10's.

How to manage the interaction:
Although taking Enalapril together with Valfect H 80 Tablet 10's may result in an interaction, they can be taken together if prescribed by your doctor. However, contact your doctor immediately if you experience signs and symptoms of hyperkalemia, such as nausea, vomiting, confusion, numbness, tingling in hands and feet, and irregular heartbeat, contact a doctor. Do not discontinue any medication without consulting a doctor.
ValsartanPotassium iodide
Severe
How does the drug interact with Valfect H 80 Tablet 10's:
Coadministration of Potassium iodide and Valfect H 80 Tablet 10's may significantly increase potassium levels in the blood, which in severe cases can lead to kidney failure.

How to manage the interaction:
Although taking Potassium iodide together with Valfect H 80 Tablet 10's may result in an interaction, they can be taken together if prescribed by a doctor. However, contact a doctor immediately if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, a weak pulse, or a slow or irregular heartbeat, contact a doctor. Do not discontinue any medication without consulting a doctor.
ValsartanTrandolapril
Severe
How does the drug interact with Valfect H 80 Tablet 10's:
The use of Trandolapril and Valfect H 80 Tablet 10's may increase the risk of side effects (low blood pressure, kidney function impairment, and hyperkalemia (high blood potassium).

How to manage the interaction:
Although taking Trandolapril together with Valfect H 80 Tablet 10's may result in an interaction, they can be taken together if prescribed by a doctor. However, contact a doctor immediately if you experience symptoms such as nausea, vomiting, confusion, numbness, tingling in hands and feet, and irregular heartbeat. Do not discontinue any medication without consulting a doctor.
ValsartanAmiloride
Severe
How does the drug interact with Valfect H 80 Tablet 10's:
Taking amiloride with Valfect H 80 Tablet 10's may increase potassium levels in the blood. (High levels of potassium can cause hyperkalemia - high level of potassium in the blood, which can lead to kidney failure, muscular paralysis, and abnormal heart rhythms).

How to manage the interaction:
Although taking amiloride and Valfect H 80 Tablet 10's together can result in an interaction, it can be taken if a doctor has prescribed it. However, consult a doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. Do not discontinue any medications without a doctor's advice.
ValsartanPotassium acetate
Severe
How does the drug interact with Valfect H 80 Tablet 10's:
Coadministration of Potassium acetate with Valfect H 80 Tablet 10's may increase the risk of side effects (low blood pressure, kidney function impairment, and hyperkalemia (high blood potassium).

How to manage the interaction:
Although taking Potassium acetate together with Valfect H 80 Tablet 10's may result in an interaction, they can be taken together if prescribed by a doctor. However, contact a doctor immediately if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, a weak pulse, or a slow or irregular heartbeat, contact a doctor. Do not discontinue any medication without consulting a doctor.
ValsartanPerindopril
Severe
How does the drug interact with Valfect H 80 Tablet 10's:
Coadministration of Perindopril with Valfect H 80 Tablet 10's may increase the risk of side effects (low blood pressure, kidney function impairment, and hyperkalemia (high blood potassium).

How to manage the interaction:
Although taking Perindopril together with Valfect H 80 Tablet 10's may result in an interaction, they can be taken together if prescribed by a doctor. However, contact a doctor immediately if you experience symptoms such as nausea, vomiting, confusion, numbness, tingling in hands and feet, and irregular heartbeat, contact a doctor. Do not discontinue any medication without consulting a doctor.

Drug-Food Interactions

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VALSARTAN-80MG+HYDROCHLOROTHIAZIDE-12.5MGPotassium rich foods
Moderate

Drug-Food Interactions

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VALSARTAN-80MG+HYDROCHLOROTHIAZIDE-12.5MGPotassium rich foods
Moderate
Common Foods to Avoid:
Lentils, Orange Juice, Oranges, Raisins, Potatoes, Salmon Dried, Spinach, Sweet Potatoes, Tomatoes, Coconut Water, Beans, Beetroot, Broccoli, Bananas, Apricots, Avocado, Yogurt

How to manage the interaction:
Consumption of Valfect H 80 Tablet 10's with potassium-containing salt substitutes may increase the potassium levels in the body. Avoid potassium-containing salt substitutes while being treated with Valfect H 80 Tablet 10's.

Diet & Lifestyle Advise

  • Keep your weight under control with BMI of 19.5-24.9.
  • Do regular physical activity or exercise for at least 150 minutes per week, or about 30 minutes most days of the week. Doing this can help you to lower your raised blood pressure by about 5 mm of Hg.
  • Limit intake of sodium chloride (table salt) in your daily diet to 2300 mg per day or less than 1500 mg is ideal for most adults.
  • If you are taking alcohol, then only one serving for women and two servings for men is advisable.
  • Quitting smoking is the best strategy to lower the risk of heart disease.
  • Avoid chronic stress as it can raise your blood pressure. Try to enjoy and spent time with your loved ones to cope with stress and practice mindfulness techniques.
  • Monitor your blood pressure daily and if there is too much fluctuation, then immediately contact your doctor.
  • Try to include heart-healthy omega 3 fatty acids-containing food drinks in your daily diet. You can also use low-fat cooking oil like olive oil, soybean oil, canola oil, and coconut oil to lower your elevated blood pressure.

Habit Forming

No

Therapeutic Class

ANTI- HYPERTENSIVES

Valfect H 80 Tablet Substitute

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Alcohol

Unsafe

You are recommended not to consume alcohol and Valfect H 80 Tablet to avoid unpleasant side effects like drowsiness, dizziness, and liver damage.

bannner image

Pregnancy

Unsafe

Valfect H 80 Tablet is not recommended during pregnancy. This medicine may cause fetal damage and can cause serious harm to the unborn baby (fetus).

bannner image

Breast Feeding

Unsafe

Valfect H 80 Tablet is known to pass breast milk, but its effect on the baby is not known. So, before breastfeeding, let your doctor know about this.

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Driving

Unsafe

Drive with caution, Valfect H 80 Tablet usually causes drowsiness and affects driving ability.

bannner image

Liver

Caution

Valfect H 80 Tablet to be taken with caution, especially if you have had a history of liver disease. Your doctor will have to change the dosage depending on your medical condition and your reaction to treatment.

bannner image

Kidney

Caution

Valfect H 80 Tablet to be taken with caution, especially if you have had a history of kidney disease. Your doctor will have to change the dosage depending on your medical condition and your reaction to treatment.

bannner image

Children

Caution

Valfect H 80 Tablet should not be used for children as the safety and efficacy of Valfect H 80 Tablet in children have not established.

FAQs

Valfect H 80 Tablet is used to lower high blood pressure (hypertension) by removing extra fluid (electrolytes) from the body.
Valfect H 80 Tablet is a combination of two medicines, namely: Valsartan and Hydrochlorothiazide. Valsartan is an angiotensin receptor blocker (ARB) that blocks the hormone angiotensin and relaxes blood vessels. This allows the blood to flow more smoothly in the blood vessels, and the heart can pump more efficiently. Hydrochlorothiazide (diuretic or water pill) removes extra water and certain electrolytes from the body. Together, both lower fluid overload, blood pressure improves blood flow and reduce the future risk of a heart attack.
Yes, Valfect H 80 Tablet can cause dizziness. It is advised to avoid driving or operate any heavy machinery while taking Valfect H 80 Tablet . In case you feel dizzy or lightheaded, it is advised to rest for some time until you feel better.
In case you have missed a dose of Valfect H 80 Tablet , you are advised to take it as soon as you remember. However, try not to miss a dose in the first place, if it's time for you to take your next dose, then do not take both doses together. Take only one dose; taking a double dose of Valfect H 80 Tablet will lead to low blood pressure.
No, you are advised to inform your doctor and monitor your blood pressure for at least two weeks before stopping the medicine. Depending upon your current blood pressure readings, there is a possibility your doctor may lower your medicine dosage and not recommend discontinuing it.
Do not use Valfect H 80 Tablet if you are pregnant, planning for pregnancy, or unable to urinate. If you have diabetes and taking Valfect H 80 Tablet with other blood pressure-lowering pills like 'aliskiren,' immediately stop taking both together and consult a doctor.
No, Valfect H 80 Tablet does not lead to weight gain as a side effect. However, if your kidney function worsens, your body may swell due to water build-up (fluid retention), causing weight gain. Advise your doctor if you feel any unexplained weight gain or swelling in your ankles, feet, or hands.
Valfect H 80 Tablet starts working within 2 weeks and may show the maximum effect within 4 weeks for most patients, but some may need 4 to 8 weeks of treatment. Continue taking Valfect H 80 Tablet for the prescribed duration to treat your condition effectively.
It is not known if Valfect H 80 Tablet affects kidney function. Valfect H 80 Tablet is not recommended for people with severe renal impairment, and it should be used with caution in patients with mild to moderate kidney problems. Please consult the doctor if you have kidney problems.
Valfect H 80 Tablet should not be taken by people who are allergic to any of its components. It is not recommended for children as the safety and efficacy have not been established. Let the doctor know if you are pregnant, breastfeeding, have liver or kidney problems, biliary cirrhosis, or cholestasis.
Valfect H 80 Tablet should be taken for as long as it has been prescribed by the doctor. It may be a lifelong treatment, as it controls but does not cure high blood pressure. Consult your doctor if you face any difficulty while taking Valfect H 80 Tablet .
Female patients of childbearing age should be aware that taking Valfect H 80 Tablet during pregnancy can cause serious health issues in the baby, including low blood pressure, skull bone problems, and kidney failure. Consult the doctor if you are planning to become pregnant or think you may be pregnant.
The common side effects of Valfect H 80 Tablet may include nausea, diarrhoea, taste change, dizziness, upset stomach, fatigue, and headache. Most of these side effects of Valfect H 80 Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Country of origin

India

Manufacturer/Marketer address

Corporate & Registered Office, Block N1, 12Th Floor, Manyata Embassy Business Park, Rachenahalli, Outer Ring Road, 560045, Bangalore
Other Info - VAL0141

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