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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

V-Pam 20Ml Inj is used to treat poisoning caused by organic phosphorus pesticides or chemicals. It is also used to treat an overdose of drugs that treat myasthenia gravis. It contains Pralidoxime, a cholinesterase reactivator. It works by reactivating the enzyme cholinesterase (mainly outside the central nervous system), which has been inactivated by phosphorylation due to an organophosphate pesticide or related compound.

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Composition :

PRALIDOXIME-25MG

Consume Type :

PARENTERAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About V-Pam 20Ml Inj

V-Pam 20Ml Inj belongs to the oxime class of drugs. Pralidoxime is used alone or together with atropine to treat poisoning caused by organic phosphorus pesticides or chemicals. It is also used to treat an overdose of drugs that treat myasthenia gravis.

V-Pam 20Ml Inj contains Pralidoxime, a cholinesterase reactivator. It works by reactivating the enzyme cholinesterase (mainly outside the central nervous system), which has been inactivated by phosphorylation due to an organophosphate pesticide or related compound.

A qualified healthcare professional will administer V-Pam 20Ml Inj. You may experience mild to moderate pain at the site of injection, blurred vision, diplopia (double vision), impaired accommodation, dizziness, headache, drowsiness, nausea, tachycardia (fast heartbeat), increased systolic and diastolic blood pressure, hyperventilation (rapid or deep breathing), and muscular weakness. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects persist, inform your doctor.

Before taking V-Pam 20Ml Inj, let your doctor know about all your medical conditions, sensitivities, and ongoing medications. Also, inform your doctor if you are pregnant, planning pregnancy, or breastfeeding. V-Pam 20Ml Inj may cause blurred vision and diplopia (double vision); it impacts your ability to drive or operate machinery.

Uses of V-Pam 20Ml Inj

Treatment of Organophosphate poisoning

Directions for Use

A qualified healthcare professional will administer V-Pam 20Ml Inj.

Medicinal Benefits

V-Pam 20Ml Inj contains Pralidoxime, a cholinesterase reactivator that belongs to the oxime class of drugs. Pralidoxime is together with another medicine called atropine to treat poisoning caused by organic phosphorus pesticides (such as diazinon, malathion, sarin and parathion). Pralidoxime injection is also used to treat an overdose of medicines (such as neostigmine, ambenonium, and pyridostigmine) that treat myasthenia gravis. It works by reactivating the enzymes (cholinesterase) blocked by many pesticides or medicines. Poisoning with these substances or drugs weakens your muscles, including those that let you breathe. Pralidoxime is used to help you regain muscle strength.

How V-Pam 20Ml Inj Works

V-Pam 20Ml Inj contains Pralidoxime, a cholinesterase reactivator. It works by reactivating the enzyme cholinesterase (mainly outside the central nervous system), which has been inactivated by phosphorylation due to an organophosphate pesticide or related compound.

Storage

Store in a cool and dry place away from sunlight

Side Effects of V-Pam 20Ml Inj

  • Mild to moderate pain at the site of injection
  • Blurred vision
  • Diplopia (double vision)
  • Impaired accommodation
  • Dizziness
  • Headache
  • Drowsiness
  • Nausea
  • Tachycardia 
  • Increased systolic and diastolic blood pressure
  • Rapid or deep breathing
  • Muscular weakness

What if I have taken an overdose of V-Pam 20Ml Inj

As V-Pam 20Ml Inj is a parenteral formulation administered by experienced medical staff, the chance of overdose may be less. However, if you think there has been an overdose or experiencing any adverse events, get medical care right away.

Drug Warnings

V-Pam 20Ml Inj is not recommended as an antidote for carbamate pesticide overdose since it may enhance carbaryl toxicity or known hypersensitivity to the drug. Before taking V-Pam 20Ml Inj, inform your doctor of all your medical problems, sensitivities, and medicines. Also, let your doctor know if you are pregnant, want to become pregnant, or are breastfeeding. Do not drive or operate machinery because V-Pam 20Ml Inj may cause diplopia (double vision), decreased accommodation, and dizziness.

Drug-Drug Interactions

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PralidoximePramlintide
Critical

Drug-Drug Interactions

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PralidoximePramlintide
Critical
How does the drug interact with V-Pam 20Ml Inj:
V-Pam 20Ml Inj and Pramlintide when used together may enhance the effects of the other, which may increase the risk of side effects. .

How to manage the interaction:
Co-administration of V-Pam 20Ml Inj with Pramlintide is not recommended as it can possibly result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

ANTIDOTES

V-Pam 20Ml Inj Substitute

Substitutes safety advice
  • Neopam 25mg Injection

    45.91per tablet
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Alcohol

Caution

Avoid consuming alcohol. Consult your doctor for more information.

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Pregnancy

Caution

Inform your doctor if you are pregnant or suspect pregnancy. Your doctor will weigh the benefits and potential risks before prescribing V-Pam 20Ml Inj.

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Breast Feeding

Caution

Caution is advised. Let your doctor know if you are a nursing mother before taking V-Pam 20Ml Inj; your doctor may suggest stopping breastfeeding for a certain period.

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Driving

Unsafe

V-Pam 20Ml Inj may cause blurred vision and diplopia (double vision). It impacts your ability to drive or operate machinery.

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Liver

Caution

Inform your doctor before receiving V-Pam 20Ml Inj if you have had a liver impairment/disorder history. Your doctor will weigh the benefits and potential risks before prescribing V-Pam 20Ml Inj.

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Kidney

Caution

Caution should be exercised. Inform your doctor before receiving V-Pam 20Ml Inj if you have had a kidney impairment/disorder history. Your doctor will weigh the benefits and potential risks before prescribing V-Pam 20Ml Inj.

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Children

Consult your doctor

Please consult your doctor. The doctor will decide the dose based on your child's age and condition.

FAQs

V-Pam 20Ml Inj is used treat Organophosphate poisoning.
V-Pam 20Ml Inj contains Pralidoxime, a cholinesterase reactivator. It works by reactivating the enzyme cholinesterase (mainly outside the central nervous system), which has been inactivated by phosphorylation due to an organophosphate pesticide or related compounds and medicines.
V-Pam 20Ml Inj is an antidote Antidote for organophosphorus nerve agent poisoning, including chlorosarin, cyclosarin (GF), R-VX, tabun (GA), sarin (GB), VX, soman (GD), chlorosoman and organophosphorus pesticides.
Pralidoxime injection is also used to treat an overdose of medicines (such as neostigmine, ambenonium, and pyridostigmine) that treat myasthenia gravis.
The common side effects of V-Pam 20Ml Inj may include mild to moderate pain at the site of injection, blurred vision, diplopia (double vision), impaired accommodation, dizziness, headache, drowsiness, nausea, tachycardia (fast heartbeat), increased systolic and diastolic blood pressure, hyperventilation (rapid or deep breathing), and muscular weakness. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects persist, inform your doctor.
V-Pam 20Ml Inj is a cholinesterase reactivator that belongs to the oxime class of drugs. It is used to treat poisoning caused by organic phosphorus pesticides or chemicals, often in combination with atropine.
V-Pam 20Ml Inj is typically administered intravenously (through a vein) or intramuscularly (into a muscle). It is usually given in a hospital setting by a healthcare professional. The administration route and dosage may vary depending on the specific situation and medical guidance.

Country of origin

India
Other Info - VPA0003

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