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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
Last Updated Jan 1, 2025 | 2:46 PM IST
Urokinase 20000IU Injection belongs to a class of drugs called antithrombotic agents. It is used in the treatment of blood clots mainly in conditions like peripheral vascular thromboembolism (blood clot in a large vein), cerebral thrombosis, cerebral infarction (stroke), and myocardial infarction (heart attack). This medicine works by converting plasminogen to the plasmin enzyme, which dissolves the blood clots, thus restoring the blood flow to the affected area.
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Composition :

UROKINASE-20000IU

Manufacturer/Marketer :

TTK Healthcare Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

About Urokinase 20000IU Injection

Urokinase 20000IU Injection belongs to a class of drugs called antithrombotic agents used to dissolve harmful blood clots in blood vessels. It is used in conditions such as peripheral vascular thromboembolism (blood clot in a large vein), cerebral thrombosis (blood clot in venous sinuses of the brain), cerebral infarction (stroke), myocardial infarction (heart attack),  and pulmonary embolism (blood clots in the lungs).

Urokinase 20000IU Injection contains urokinase that works by converting plasminogen to the enzyme plasmin. Plasmin degrades fibrin clots as well as fibrinogen and some other plasma proteins. It effectively dissolves the blood clots, restoring the blood flow to the affected area.

Urokinase 20000IU Injection will be administered by a healthcare professional. In some cases, Urokinase 20000IU Injection may cause unusual bleeding, nausea, vomiting, and loss of appetite. Most of these side effects do not necessitate medical treatment and fade away with time. Please visit your doctor if the side effects persist or worsen.

If you are pregnant or breastfeeding, inform your doctor before taking Urokinase 20000IU Injection. Keep your doctor updated on your medical condition and medications to rule out any potential interactions. Avoid consuming alcohol along with Urokinase 20000IU Injection as it could increase the risk of bleeding. Urokinase 20000IU Injection should not be given to children because its safety and effectiveness have not been proven.

Uses of Urokinase 20000IU Injection

Treatment of Blood clots

Medicinal Benefits

Urokinase 20000IU Injection belongs to a class of drugs known as antithrombotic medications. Urokinase 20000IU Injection contains urokinase. It works by dissolving or lysing the harmful or unwanted blood clots in the blood vessels. Thus it restores the blood flow to the affected blood vessels, preventing various illnesses caused by blood clots. It is used in conditions such as peripheral vascular thromboembolism (blood clot in a large vein), cerebral thrombosis (blood clot in venous sinuses of the brain), cerebral infarction (stroke), myocardial infarction (heart attack),  and pulmonary embolism (blood clots in the lungs).

Side Effects of Urokinase 20000IU Injection

  • Unusual bleeding
  • Nausea
  • Vomiting
  • Loss of appetite

Directions for Use

Urokinase 20000IU Injection is given as an intravenous (into a vein) injection by a doctor or nurse. Do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Before taking Urokinase 20000IU Injection, tell your doctor if you are pregnant or breastfeeding. Urokinase 20000IU Injection should be used with caution in elderly people because they are at significant risk of bleeding. If you have active tuberculosis, stomach ulcers, severe uncontrolled arterial hypertension, bleeding abnormalities, severe hepatic or renal diseases, inform your doctor before taking Urokinase 20000IU Injection. Also, let your doctor know if you have had a recent cerebrovascular accident, as well as intracranial or intraspinal surgery. Inform your doctor that you take Urokinase 20000IU Injection if are due to undergo surgery. You should avoid alcohol because it increases the risk of bleeding. Urokinase 20000IU Injection is not recommended for children since its safety and effectiveness have not been proven.

Therapeutic Class

ANTICOAGULANT/ANTITHROMBOTIC

Diet & Lifestyle Advise

  • Avoid cranberry juice, grapefruit juice, noni juice, pomegranate juice, and green tea.
  • Make no dietary changes without first consulting your doctor.
  • You should avoid alcohol because it increases the risk of bleeding.
  • Maintain a healthy cholesterol and triglyceride level.
  • Maintain a healthy weight and exercise routine to keep your heart healthy.

Habit Forming

No

How Urokinase 20000IU Injection Works

Urokinase 20000IU Injection contains urokinase that works by converting plasminogen to the enzyme plasmin. Plasmin degrades fibrin clots as well as fibrinogen and some other plasma proteins. It effectively dissolves the blood clots, restoring the blood flow to the affected area.

What if I have taken an overdose of Urokinase 20000IU Injection

Since Urokinase 20000IU Injection is administered by a healthcare professional, an overdose is unlikely to occur. However, seek medical attention if you experience any unusual symptoms.
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Alcohol

Unsafe

Avoid the consumption of alcohol with Urokinase 20000IU Injection as it may increase the risk of bleeding.

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Pregnancy

Unsafe

Urokinase 20000IU Injection is not recommended during pregnancy or immediately after the delivery unless advised by the doctor. Please consult a doctor if you are pregnant or planning for pregnancy.

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Breast Feeding

Unsafe

Breastfeeding is not recommended during treatment with Urokinase 20000IU Injection. Please consult a doctor if you have any concerns.

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Driving

Caution

It is unclear whether Urokinase 20000IU Injection impacts your ability to drive or operate machinery. However, drive or operate machinery only if you are alert.

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Liver

Caution

Let your doctor know if you have a history of liver diseases/conditions. Your doctor will prescribe only if the benefits outweigh the risks.

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Kidney

Caution

Let your doctor know if you have a history of kidney diseases/conditions. Your doctor will prescribe only if the benefits outweigh the risks.

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Children

Unsafe

Urokinase 20000IU Injection is not recommended for children as safety and effectiveness have not been established.

Country of origin

India
Other Info - UR54951

Author Details

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FAQs

Urokinase 20000IU Injection belongs to a class of drugs called antithrombotic agents used to dissolve harmful blood clots in blood vessels. It is used in conditions such as peripheral vascular thromboembolism (blood clot in a large vein), cerebral thrombosis (blood clot in venous sinuses of the brain), cerebral infarction (stroke), myocardial infarction and pulmonary embolism (blood clots in the lungs).
Urokinase 20000IU Injection works by dissolving the harmful blood clots in the blood vessels. This restores the blood flow to the affected blood vessels, preventing various illnesses caused by blood clots.
Yes, Urokinase 20000IU Injection raises the possibility of bleeding. Always exercise caution when engaging in activities that could result in an injury or bleeding. Notify your doctor right away if you notice any unusual bruises or bleeding.
To determine blood clotting time, tests such as platelet count, factor V assay, fibrinogen level test, prothrombin time test (PT or PT-INR), and the INR (international normalised ratio) are utilised.
If you are scheduled for surgery, please consult your doctor. The doctor may advise you to stop taking Urokinase 20000IU Injection a few days before surgery because it increases the chance of bleeding during surgery.
Urokinase 20000IU Injection is not recommended for use in people with severe uncontrolled high blood pressure.
Urokinase 20000IU Injection may interact with certain medications such as anticoagulant medications (warfarin) and medications with platelet antiaggregant effects (aspirin, ticlopidine hydrochloride, dipyridamole). So, avoid taking these medications together. However, it is better to consult a doctor before taking any medication while on treatment with Urokinase 20000IU Injection to ensure safety.
The common side effects of Urokinase 20000IU Injection that may occur in some individuals such as unusual bleeding, nausea, vomiting, and loss of appetite. Most of these side effects do not necessitate medical treatment and fade away with time. Please visit your doctor if the side effects persist or worsen.

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