UNIWARFIN 5MG TABLET

UNIWARFIN 5MG TABLET is primarily used to prevent and treat deep vein thrombosis (blood clots in leg veins) and pulmonary embolism (blood clots in the lung) by reducing the formation of a blood clot. Deep vein thrombosis is a medical condition in which blood clots form in deep veins, usually in the legs. Pulmonary embolism is a condition in which blood clot blocks the arteries in the lungs.

UNIWARFIN 5MG TABLET contains Warfarin, which works by inhibiting the production of clotting factors by decreasing the action of vitamin K. This prevents the conversion of fibrinogen (soluble protein) to fibrin (insoluble protein), thereby preventing blood clot formation.

Take UNIWARFIN 5MG TABLET with or without food as advised by the doctor and swallow it as a whole with a glass of water. Do not crush, chew or break it. Your doctor will advise you on how often you take your tablets based on your medical condition. Some people may experience unusual bleeding or skin rash. Most of these side effects of UNIWARFIN 5MG TABLET do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are known to be allergic to UNIWARFIN 5MG TABLET or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, it is advised to consult a doctor before using UNIWARFIN 5MG TABLET. If you have a stomach ulcer, kidney or liver problems, high blood pressure, or bleeding problems, inform your doctor before taking UNIWARFIN 5MG TABLET. It would help if you had frequent INR (International Normalized Ratio) or prothrombin time tests to measure your blood clotting time, as UNIWARFIN 5MG TABLET prolongs bleeding time. You must be cautious while shaving and brushing your teeth to avoid too much bleeding from the injury site.  

UNIWARFIN 5MG TABLET belongs to a class of drugs known as anticoagulants or blood thinners. UNIWARFIN 5MG TABLET is primarily used to prevent and treat deep vein thrombosis (blood clots in leg veins) and pulmonary embolism (blood clots in the lung) by reducing the formation of a blood clot. UNIWARFIN 5MG TABLET works by inhibiting the production of clotting factors by decreasing the action of vitamin K. This prevents the conversion of fibrinogen (soluble protein) to fibrin (insoluble protein), thereby preventing blood clot formation.

• Unusual bleeding
• Skin rash

UNIWARFIN 5MG TABLET should be used with caution in children. Prolonged use of UNIWARFIN 5MG TABLET may cause hair loss. Regular blood tests are recommended while taking UNIWARFIN 5MG TABLET to check the time taken for your blood to clot and the level of platelets (blood cells). If you have a painful skin rash, inform your doctor immediately as it may be due to a serious condition called calciphylaxis (accumulation of calcium in small blood vessels of skin and fat tissues) which may cause painful skin ulcers, blood clots, and serious skin infections. Patients with chronic kidney disease are at high risk of getting calciphylaxis. If you have any high blood pressure, kidney, liver, or heart problems, please inform your doctor before taking UNIWARFIN 5MG TABLET so that the dose may be adjusted accordingly. UNIWARFIN 5MG TABLET may cause serious side effects and death of skin tissue (skin necrosis or gangrene). Call your doctor if you have pain, color, or temperature change in any area of your body or purple toes syndrome. Before undergoing any type of surgery tell your doctor that you are taking UNIWARFIN 5MG TABLET. Your doctor might tell you to stop taking UNIWARFIN 5MG TABLET. UNIWARFIN 5MG TABLET is pregnancy category D medicine and can cause birth defects, or miscarriage. So, if you are pregnant or planning for pregnancy or are a nursing mother tell your doctor that you are taking UNIWARFIN 5MG TABLET. UNIWARFIN 5MG TABLET should be used with caution in patients with severe Anemia (low RBC count), malignancies (any cancer), and Trauma (injuries).

Drug-Drug Interaction: UNIWARFIN 5MG TABLET may have interaction with pain killers (aspirin, ibuprofen, phenylbutazone, feprazone, oxyphenbutazone), antidiabetic drugs (glucagon, tolbutamide, phenformin), heart-related medicines (quinidine, amiodarone, propafenone), antidepressants (nortriptyline, amitriptyline), antifungal drugs (fluconazole, miconazole, ketoconazole), antibiotics (ciprofloxacin, erythromycin, latamoxef, griseofulvin, metronidazole, norfloxacin, rifampicin, sulphonamides, aztreonam, neomycin, cephamandole, co-trimoxazole, chloramphenicol, nalidixic acid, tetracyclines), vitamin K supplements, gout medicine (allopurinol) and sedatives (ethchlorvynol, glutethimide)

Drug-Food Interaction: UNIWARFIN 5MG TABLET may interact with cranberry juice, noni juice, grapefruit juice, pomegranate juice, and green tea. Avoid foods rich in vitamin K such as coriander, cabbage, spinach, broccoli, collard greens, kale (leaf cabbage), black liquorice, turnip greens, avocados, and brussels sprouts as they may affect the activity of UNIWARFIN 5MG TABLET. Also, avoid alcohol intake as it may increase the risk of bleeding.

Drug-Disease Interaction: Use with caution in patients with kidney, liver, or bleeding problems, peptic ulcer, and high blood pressure.

• ASPIRIN
• IBUPROFEN
• PHENYLBUTAZONE
• FEPRAZONE
• OXYPHENBUTAZONE
• GLUCAGON
• TOLBUTAMIDE
• PHENFORMIN
• QUINIDINE
• AMIODARONE
• PROPAFENONE
• NORTRIPTYLINE
• AMITRIPTYLINE
• FLUCONAZOLE
• MICONAZOLE
• KETOCONAZOLE
• CIPROFLOXACIN
• ERYTHROMYCIN
• LATAMOXEF
• GRISEOFULVIN
• METRONIDAZOLE
• NORFLOXACIN
• RIFAMPICIN
• AZTREONAM
• NEOMYCIN
• CEPHAMANDOLE
• CHLORAMPHENICOL
• NALIDIXIC ACID
• ALLOPURINOL
• GLUTETHIMIDE

• Avoid making any changes in your diet without first talking to your doctor.

• Opt for foods that are high in vitamin K (liver, leafy green vegetables, or vegetable oils) as UNIWARFIN 5MG TABLET may lower Vitamin K in your body.

• Cranberry juice, grapefruit juice, noni juice, and pomegranate juice may interact with UNIWARFIN 5MG TABLET and lead to unwanted side effects. Hence try to avoid these juices while taking UNIWARFIN 5MG TABLET.

• Avoid drinking alcohol as it increases risk of gastrointestinal ulcer/bleeding.

• You should have regular platelet count, factor V assay, fibrinogen level test, prothrombin time test (PT or PT-INR) and the INR (international normalised ratio) to analyze your blood clotting time.

Deep vein thrombosis (blood clots in legs) is a medical condition in which blood clots form in deep veins usually in the legs. The symptoms include leg pain or swelling. Pulmonary embolism (blood clots in the lung) is a chronic condition that occurs as the blood clots break and travel to the lungs from deep veins in the legs or other parts of the body. The symptoms of pulmonary embolism include cough, chest pain, and shortness of breath.