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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Uniphos 200 Injection is used to treat Cancer. It contains 'Cyclophosphamide' that works by stopping or slowing the growth of cancer cells in the body. Thereby, It helps treat Cancer. Additionally, It is used to treat minimal change nephrotic syndrome (kidney disease) in paediatric patients. It suppresses the body's immune system, thereby helping treat nephrotic syndrome. Common side effects of Uniphos 200 Injection are nausea, vomiting, stomatitis (inflamed and sore mouth), weakness, malaise (general discomfort), fever, leukopenia (low white blood cell count), and alopecia (hair loss).
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Manufacturer/Marketer :

United Biotech Pvt Ltd

Consume Type :

PARENTERAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Uniphos 200 Injection

Uniphos 200 Injection belongs to the group of medicines called alkylating agents used to treat malignant diseases such as Hodgkin's disease, mixed-cell type lymphoma, lymphocytic lymphoma, histiocytic lymphoma, multiple myeloma, Burkitt's lymphoma, leukaemia,  neuroblastoma, retinoblastoma, adenocarcinoma of the ovary, mycosis fungoides, Ewing's sarcoma, small cell lung cancer, advanced/metastatic neuroblastoma and breast carcinoma. Additionally, Uniphos 200 Injection is used to treat minimal change nephrotic syndrome (kidney disease) in paediatric patients.
 
Uniphos 200 Injection contains 'Cyclophosphamide' that works by stopping or slowing the growth of cancer cells in the body. Thereby, Uniphos 200 Injection helps treat cancer. Uniphos 200 Injection suppresses the body's immune system and helps treat nephrotic syndrome.
 
In some cases, Uniphos 200 Injection may cause nausea, vomiting, stomatitis (inflamed and sore mouth), weakness, malaise (general discomfort), fever, leukopenia (low white blood cell count), and alopecia (hair loss). You are advised to talk to your doctor if the side effects persist or worsen.
 
Consult your doctor if you are pregnant, planning pregnancy, or breastfeeding. Uniphos 200 Injection may cause dizziness, so drive only if you are alert. Inform your doctor about your health condition and medications to rule out any side effects/interactions.

Uses of Uniphos 200 Injection

Treatment of Cancer and nephrotic syndrome (kidney disease)

Directions for Use

Uniphos 200 Injection will be administered by a healthcare professional; do not self-administer.

Medicinal Benefits

Uniphos 200 Injection belongs to the group of medicines called alkylating agents used to treat malignant diseases such as Hodgkin's disease (cancer of the lymphatic system), mixed-cell type lymphoma, lymphocytic lymphoma, histiocytic lymphoma, multiple myeloma (cancer of plasma cells), Burkitt's lymphoma, leukaemia (blood cancer), neuroblastoma (cancer commonly found in the adrenal glands), retinoblastoma (eye cancer), adenocarcinoma of the ovary, mycosis fungoides, Ewing's sarcoma (cancer in and around the bones), small cell lung cancer, advanced/metastatic neuroblastoma and breast carcinoma. Uniphos 200 Injection works by stopping or slowing the growth of cancer cells in the body. Thereby, Uniphos 200 Injection helps treat cancer. Additionally, Uniphos 200 Injection is used to treat minimal change nephrotic syndrome (kidney disease) in paediatric patients. Uniphos 200 Injection suppresses the body's immune system, thereby helping treat nephrotic syndrome.

How Uniphos 200 Injection Works

Uniphos 200 Injection contains 'Cyclophosphamide' that works by stopping or slowing the growth of cancer cells in the body. Thereby, Uniphos 200 Injection helps treat cancer. Uniphos 200 Injection suppresses the body's immune system and helps treat nephrotic syndrome.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Uniphos 200 Injection

  • Nausea
  • Vomiting
  • Stomatitis (inflamed and sore mouth)
  • Weakness
  • Malaise (general discomfort)
  • Fever
  • Leukopenia (low white blood cell count)
  • Alopecia (hair loss)

What if I have taken an overdose of Uniphos 200 Injection

As Uniphos 200 Injection is a parenteral formulation administered by experienced medical staff, the chance of overdose may be less. However, if you think there has been an overdose or experiencing any adverse events, get medical care right away.

Drug Warnings

Do not take Uniphos 200 Injection if you are allergic to any of its components. Inform your doctor if you have acute infections, bone marrow depression, urinary tract infections, urinary outflow/obstruction, liver or kidney problems, or urinary or respiratory symptoms. Consult your doctor if you are pregnant or breastfeeding. Uniphos 200 Injection may cause myelosuppression, immunosuppression, bone marrow failure, and infections; consult your doctor if you have any concerns.

Drug-Drug Interactions

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CyclophosphamideNalidixic acid
Critical
CyclophosphamideCidofovir
Critical

Drug-Drug Interactions

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CyclophosphamideNalidixic acid
Critical
How does the drug interact with Uniphos 200 Injection 1's:
Co-administration of Nalidixic acid with Uniphos 200 Injection 1's may cause an increase in the risk of side effects.

How to manage the interaction:
Co-administration of Uniphos 200 Injection 1's and Nalidixic acid can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like bruising or bleeding, unusual weakness, nausea, stomach pain, low fever, or loss of appetite, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
CyclophosphamideCidofovir
Critical
How does the drug interact with Uniphos 200 Injection 1's:
Co-administration of Uniphos 200 Injection 1's and Cidofovir may increase the risk of kidney problems.

How to manage the interaction:
Taking Cyclophosphamine with Cidofovir is not recommended, please consult your doctor before taking it. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm contact your doctor immediately. Do not discontinue any medications without consulting a doctor
CyclophosphamideBusulfan
Severe
How does the drug interact with Uniphos 200 Injection 1's:
Co-administration of Uniphos 200 Injection 1's with Busulfan can increase the risk of side effects.

How to manage the interaction:
Although there is an interaction between Busulfan and Uniphos 200 Injection 1's, they can be taken together if prescribed by a doctor. However, if you experience any vomiting, diarrhea, mouth sores, or stomach pain, contact your doctor immediately. Do not stop using any medications without talking to your doctor.
CyclophosphamideCertolizumab
Severe
How does the drug interact with Uniphos 200 Injection 1's:
When Uniphos 200 Injection 1's is taken with Certolizumab, may increase the risk or severity of infections.

How to manage the interaction:
There may be a possibility of interaction between Uniphos 200 Injection 1's and Certolizumab, but it can be taken if prescribed by a doctor. If you have any of these symptoms, it's important to contact a doctor right away: fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, pain or burning during urination. Do not discontinue any medications without consulting a doctor.
CyclophosphamideLevobupivacaine
Severe
How does the drug interact with Uniphos 200 Injection 1's:
Co-administration of Uniphos 200 Injection 1's with Levobupivacaine can increase the risk of methemoglobinemia (low level of oxygen in the blood).

How to manage the interaction:
Co-administration of Levobupivacaine with Uniphos 200 Injection 1's can possibly result in an interaction, but it can be taken if a doctor has advised it. Keep a close eye on any signs or symptoms of Methemoglobinemia. If you notice any of these symptoms like gray skin, feeling sick, headaches, dizziness, tiredness, or trouble breathing, make sure to call a doctor right away. Do not stop using any medications without talking to a doctor.
CyclophosphamideLeflunomide
Severe
How does the drug interact with Uniphos 200 Injection 1's:
Taking Uniphos 200 Injection 1's with Leflunomide may increase the risk of serious infections.

How to manage the interaction:
Although there is a possible interaction, Uniphos 200 Injection 1's can be taken with Leflunomide if prescribed by the doctor. Consult the doctor immediately if you develop signs and symptoms of infection such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue the medication without consulting a doctor.
CyclophosphamideTenofovir alafenamide
Severe
How does the drug interact with Uniphos 200 Injection 1's:
Co-administration of Tenofovir alafenamide may cause kidney problems, and combining it with Uniphos 200 Injection 1's may increase the risk.

How to manage the interaction:
Although there is a possible interaction, Uniphos 200 Injection 1's can be taken with Tenofovir alafenamide if prescribed by the doctor. Consult the doctor if you develop signs and symptoms of kidney damage such as nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not stop any medication without consulting a doctor.
CyclophosphamideLidocaine
Severe
How does the drug interact with Uniphos 200 Injection 1's:
Taking Lidocaine with Uniphos 200 Injection 1's may increase the risk of methemoglobinemia (a rare condition that can lead to oxygen deprivation in tissues and vital organs due to reduced oxygen-carrying capacity of the blood).

How to manage the interaction:
Although there is a possible interaction, Uniphos 200 Injection 1's can be taken with lidocaine if prescribed by the doctor. However, consult the doctor if you experience gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, weakness, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion. Do not discontinue the medication without consulting a doctor.
CyclophosphamideClozapine
Severe
How does the drug interact with Uniphos 200 Injection 1's:
Taking Clozapine and Uniphos 200 Injection 1's may increase the risk of infection.

How to manage the interaction:
Taking Uniphos 200 Injection 1's with Clozapine can possibly lead to an interaction. However, they can be taken together if prescribed by the doctor. Consult the doctor if you experience signs and symptoms of infection such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue the medication without consulting a doctor.
CyclophosphamideTofacitinib
Severe
How does the drug interact with Uniphos 200 Injection 1's:
Taking Uniphos 200 Injection 1's with Tofacitinib may increase the risk of serious infections.

How to manage the interaction:
Although there is a possible interaction, Uniphos 200 Injection 1's can be taken with Tofacitinib if prescribed by the doctor. Consult the doctor immediately if you develop signs and symptoms of infection such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue the medication without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Avoid smoking and alcohol consumption.
  • Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, herbs, and spices in your food.
  • Avoid fast food, fried food, processed meats, refined carbs and added sugar.
  • Get optimal sleep; rest well.

Habit Forming

No

Therapeutic Class

CHEMOTHERAPY

Uniphos 200 Injection Substitute

Substitutes safety advice
  • Endoxan N 200 mg Injection 1's

    65.25per tablet
  • Cycloxan 200 mg Injection 1's

    62.10per tablet
  • CYCLOCEL 200MG INJECTION

    31.50per tablet
  • Phoxelon 200 Injection 1's

    37.40per tablet
  • Cyphos 200 mg Injection 1's

    36.00per tablet
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Alcohol

Caution

You are recommended to avoid alcohol consumption as it may worsen the risk of cyclophosphamide-induced nausea and vomiting.

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Pregnancy

Caution

It is not recommended for use in pregnancy as it may harm your foetus. Hence, if you are pregnant or planning pregnancy, inform your doctor before receiving Uniphos 200 Injection. Your doctor may prescribe this medicine only if the benefits outweigh the risks.

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Breast Feeding

Unsafe

It is not recommended for use in breastfeeding as it may pass into breast milk and harm your infant. Hence, if you are breastfeeding, inform your doctor before receiving Uniphos 200 Injection. Avoid breastfeeding during treatment with Uniphos 200 Injection and for one week after the last dose.

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Driving

Caution

Uniphos 200 Injection may cause dizziness. Do not drive or operate heavy machinery until you are alert.

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Liver

Caution

If you have a pre-existing or a history of liver disease, inform your doctor before receiving Uniphos 200 Injection. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Kidney

Caution

If you have a history of kidney diseases, inform your doctor before receiving Uniphos 200 Injection. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Children

Consult your doctor

Please consult your doctor. Your doctor will with the benefits and risks before prescribing this medicine based on your child's medical condition.

FAQs

Uniphos 200 Injection is used to treat Cancer and nephrotic syndrome (kidney disease).
Uniphos 200 Injection works by stopping or slowing down the growth of cancer cells in the body. Thereby, Uniphos 200 Injection helps treat cancer. Uniphos 200 Injection suppresses the body's immune system and helps treat nephrotic syndrome.
Uniphos 200 Injection might impair fertility and interfere with oogenesis (development of ovum) and spermatogenesis (development of sperm). Please consult your doctor if you have any concerns.
Men should avoid fathering a child during the treatment and for six months following discontinuation of therapy.
Uniphos 200 Injection might interfere with normal wound healing. Therefore, be cautious while handling sharp objects. Consult your doctor if you notice unusual bleeding or bruising or if the wounds do not heal properly.

Country of origin

INDIA

Manufacturer/Marketer address

FC/B-1 (Extn.), Mohan Co-operative Industrial Estate Mathura Road, New Delhi - 110 044.
Other Info - UNI0080

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Keep Refrigerated. Do not freeze.Prepaid payment required.

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