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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 9, 2024 | 12:38 PM IST
Udivor-Plus Tablet is used to treat primary biliary cirrhosis and gallstones. It contains Ursodeoxycholic acid and Silymarin which works by decreasing the production of cholesterol and protecting the liver. In some cases, this medicine may cause side effects such as abdominal discomfort, diarrhoea, nausea, rash, dizziness, indigestion, and weakness. Before taking this medicine, inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Prescription drug

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Manufacturer/Marketer

Vasu Organics Pvt Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Udivor-Plus Tablet

Udivor-Plus Tablet belongs to a group of medicines called the biliary agent or gall stone dissolution agents used to treat primary biliary cirrhosis and gall stones. Primary biliary cholangitis, formerly known as primary biliary cirrhosis, is an autoimmune disease caused by damage of bile ducts in the liver. Biliary cirrhosis causes a build-up of bile in the liver, which leads to liver damage.  
Udivor-Plus Tablet is a combination of two drugs, namely: Ursodeoxycholic acid and Silymarin. Ursodeoxycholic acid helps in decreasing the production of cholesterol in the blood, thereby dissolving gall bladder stones. Silymarin has immunomodulatory, antioxidant and anti-fibrotic properties. Udivor-Plus Tablet has a protective effect on the liver cells and the immune system, thereby helps in improving liver function.
 
You are advised to take Udivor-Plus Tablet for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side effects such as abdominal discomfort, diarrhoea, nausea, rash, dizziness, indigestion, and weakness. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
 
Do not discontinue Udivor-Plus Tablet without consulting your doctor. To treat your condition effectually, continue taking Udivor-Plus Tablet for as long as prescribed. Consult your doctor before taking Udivor-Plus Tablet if you are pregnant or breastfeeding. Udivor-Plus Tablet should be given to children only if prescribed by the doctor. Avoid consuming alcohol along with Udivor-Plus Tablet as it could lead to liver damage. Keep your doctor informed about your health condition and medicines to rule out any side effects.

Uses of Udivor-Plus Tablet

Treatment of Gall stones, primary biliary cirrhosis.

Medicinal Benefits

Udivor-Plus Tablet belongs to a group of medicines called the biliary agent or gall stone dissolution agents used to treat gall stones, primary biliary cholangitis (an autoimmune disease of the liver), and excess cholesterol in bile. Udivor-Plus Tablet contains ursodeoxycholic acid and silymarin. Ursodeoxycholic acid is a naturally occurring bile acid that breaks down the cholesterol formed into gall bladder stones, thereby dissolving the stones. Silymarin has immunomodulatory, antioxidant and anti-fibrotic properties. Udivor-Plus Tablet has a protective effect on the liver cells and the immune system, thereby helps in improving liver function. Udivor-Plus Tablet decreases the amount of cholesterol produced by the liver and absorbed by the intestine. In patients with primary biliary cirrhosis, Udivor-Plus Tablet increases the bile flow.

Directions for Use

Take Udivor-Plus Tablet with food. Swallow Udivor-Plus Tablet as a whole with a glass of water; do not chew or crush it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Udivor-Plus Tablet

  • Abdominal discomfort
  • Diarrhoea
  • Nausea
  • Rash
  • Dizziness
  • Indigestion
  • Weakness

Drug Warnings

Do not take Udivor-Plus Tablet if you are allergic to any of its components; if you have inflammation of gall bladder and bile ducts, narrowing or blockage of bile ducts, biliary colic, calcified gallstones, improper constriction of the gallbladder, gastric or duodenal ulcer. Inform your doctor before taking Udivor-Plus Tablet if you have variceal bleeding (high blood pressure in portal veins), ascites (excess abdominal fluid), liver encephalopathy or liver disease. Consult your doctor before taking Udivor-Plus Tablet if you are pregnant or breastfeeding. Udivor-Plus Tablet should be given to children only if prescribed by the doctor. Avoid consuming alcohol with Udivor-Plus Tablet as it could lead to increased liver damage. Keep your doctor informed about your health condition and medicines to rule out any unpleasant side effects.

Drug Interactions

Drug-Drug Interactions: Udivor-Plus Tablet may interact with antibiotics (ciprofloxacin and dapsone), antihypertensive agents (nitrendipine), immunosuppressants (cyclosporine), hormone (oestrogen), antacids (aluminium hydroxide, aluminium carbonate, magaldrate).

Drug-Food Interactions: No interactions found/established.

Drug-Disease Interactions: Inform your doctor if you have biliary obstruction or liver impairment.

Drug-Drug Interactions Checker List

  • CIPROFLOXACIN
  • DAPSONE
  • NITRENDIPINE
  • CYCLOSPORINE
  • ESTROGEN
  • ALUMINIUM HYDROXIDE
  • ALUMINUM CARBONATE
  • MAGALDRATE

Habit Forming

No

Diet & Lifestyle Advise

  • Include foods such as bell peppers, citrus fruits, leafy vegetables, tomatoes, milk, fish, low-fat dairy, beans, nuts, lentils, tofu and tempeh in your diet.
  • Eat a healthy, well-balanced diet that includes fruits and vegetables.
  • Foods rich in Vitamin B, C and calcium, are good for the gallbladder.
  • Plant-based protein foods such as beans, nuts, lentils, tofu and tempeh help prevent gallbladder disease.
  • Avoid high-fat, trans-fat, and processed foods.
  • White bread, white pasta and sugars should be avoided.
  • Avoid tobacco and alcohol consumption.

Disease/Condition Glossary

Primary biliary cholangitis: Primary biliary cholangitis, formerly known as primary biliary cirrhosis, is an autoimmune disease caused by damage of bile ducts in the liver. Bile ducts are the small channels that carry the bile (digestive fluid) from the liver to the small intestine, where it breaks down fats and aids in its absorption. Biliary cirrhosis causes a build-up of bile in the liver, which leads to liver damage.  

Gallbladder stones: The gallbladder is a small organ located below the liver that stores bile, a liquid that helps with digestion. Excess cholesterol in bile leads to the formation of gallstones. Gallstones can cause pain in the abdomen, dark urine and stools, indigestion, diarrhoea, nausea, and vomiting.

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Alcohol

Unsafe

Avoid consumption of alcohol while taking Udivor-Plus Tablet as it may cause liver damage.

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Pregnancy

Caution

Please consult your doctor if you have any concerns regarding this; your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Consult your doctor if you are breastfeeding; your doctor will decide whether Udivor-Plus Tablet can be taken by breastfeeding mothers or not.

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Driving

Safe if prescribed

Udivor-Plus Tablet does not affect your ability to drive. However, you are advised to omit driving if you experience dizziness.

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Liver

Caution

Dose adjustment may be needed. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Caution

Udivor-Plus Tablet should be given to children only if prescribed by the doctor.

Country of origin

India

Manufacturer/Marketer address

Vasu's Pharma House, #3-6-516/4, 5th Floor, St, No.6, Himayath Nagar, Hyderabad - 500 029
Other Info - UDI0043

Author Details

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FAQs

Udivor-Plus Tablet contains Ursodeoxycholic acid and Silymarin. Ursodeoxycholic acid helps in decreasing the production of cholesterol in the blood, thereby dissolving gall bladder stones. Silymarin has immunomodulatory, antioxidant and anti-fibrotic properties. Udivor-Plus Tablet has a protective effect on the liver cells and the immune system, thereby helps in improving liver function.
Do not discontinue Udivor-Plus Tablet without consulting your doctor. To treat your condition effectually, continue taking Udivor-Plus Tablet for as long as prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking Udivor-Plus Tablet.
Diarrhoea might be a side-effect of Udivor-Plus Tablet. Drink lots of fluids and eat non-spicy food if you experience diarrhoea. If you find blood in stools (tarry stools) or if you have severe diarrhoea consult your doctor. Do not take anti-diarrheal medicine on your own.
Avoid taking aluminium-containing antacids along with Udivor-Plus Tablet as they might interfere with the absorption of Udivor-Plus Tablet. Maintain a gap of 2 hours between both.
Oral contraceptives (oestrogen) might promote the formation of gallstones. Consult your doctor if you have any concerns regarding this; your doctor may advise other methods of contraception.

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