Twinnebi 2.5 Tablet belongs to a class of medications called 'anti-hypertensives', primarily used to treat high blood pressure. Hypertension is a disease associated with increased blood pressure inside blood vessels. Hypertension is a long-term disease that can lead to complications like heart attack, heart stroke & long-term kidney diseases.

Twinnebi 2.5 Tablet contains Cilnidipine & Nebivolol. Cilnidipine is a calcium channel blocker that allows the blood to flow more smoothly and the heart to pump more efficiently. Nebivolol is a beta blocker which works by slowing heart rate to improve blood circulation and decrease blood pressure. Together, Twinnebi 2.5 Tablet helps treat hypertension.

In some cases, you may experience headache, nausea, dizziness, Tiredness, increased potassium level, constipation, oedema,  cold extremities, and low blood pressure. Most of these side effects of Twinnebi 2.5 Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, reach out to your doctor.

Try not to stop taking this medicine on your own, as it may cause a rise in blood pressure and can increase the risk of getting heart disease and stroke. Consult the doctor if you are pregnant or breastfeeding. It should not be given to children less than 12 years of age. Do not use Twinnebi 2.5 Tablet if you have low blood pressure (hypotension) or cardiogenic shock (sudden stopping of blood flow to the heart).

Twinnebi 2.5 Tablet is primarily used to treat hypertension (high blood pressure). It is a combination of two medicines, Cilnidipine & Nebivolol, which help lower raised blood pressure effectively. Cilnidipine is a calcium channel blocker that relaxes blood vessels, thus decreasing blood pressure to normal levels. This allows the blood to flow more smoothly and the heart to pump more efficiently. Nebivolol is a beta blocker that helps in relaxing the heart by blocking the action of certain natural substances in the body. Twinnebi 2.5 Tablet lowers your blood pressure and reduces your risk of having a stroke, a heart attack, other heart problems or kidney problems in the future.

• Headache
• Slow heart rate
• Constipation
• Cold extremities
• Nausea
• Sleepiness
• Tiredness
• Palpitations
• Ankle swelling
• Flushing (warm cheeks, necks, ears)

Talk to your doctor or pharmacist before taking Twinnebi 2.5 Tablet if you experience shortness of breath or dizziness, an abnormally slow heart rate, have heart diseases due to decreased blood flow to heart muscles, have poor blood flow towards the extremities of the body such as finger, hands, and feet (Raynaud’s disease), experience pain, tension and weakness in the legs when walking which is relieved by rest, have a persistent obstruction of your airway such as chronic bronchitis, have diabetes, as it can hide the warning signs of low sugar levels or overactivity of the thyroid gland (hyperthyroidism). Also, inform your doctor if you are being treated with any other drugs which lower your blood pressure.

Drug-Drug Interaction: Care should be exercised when Twinnebi 2.5 Tablet is taken with quinidine(used for irregular heartbeat), phenytoin (anti-seizure medication), rifampicin (antibiotic), erythromycin (antibiotic), antipsychotics & hypertensive drugs.

Drug-Food Interaction:  Twinnebi 2.5 Tablet should not be taken with grape juice as it may decrease the drug's absorption.

Drug-Disease Interaction: Twinnebi 2.5 Tablet should not be used in people with diabetes, irregular heartbeat, low blood pressure, allergies, and diseases in which low blood circulation to the hands and feet is experienced.

• PHENYTOIN
• RIFAMPICIN
• ERYTHROMYCIN
• QUINIDINE

• Keep your weight under control with BMI (Body Mass Index) 19.5-24.9.
• Regular physical activity or exercise for at least 150 minutes per week, or about 30 minutes most days of the week, can help lower your raised blood pressure by about 5 mm of Hg.
• Opt for a diet rich in whole grains, fruits, veggies, and low-fat dairy products.
• Limit your intake of sodium chloride (table salt) to 2300 mg per day, or less than 1500 mg is ideal for most adults.
• If you are taking alcohol, then only one serving for women and two serving for men is advisable.
• Quitting smoking is the best strategy to lower the risk of heart disease. Avoid chronic stress, as it can raise your blood pressure. Try to enjoy and spend time with your loved ones to cope with stress and practice mindfulness techniques.
• Monitor your blood pressure daily, and if there is too much fluctuation, then immediately contact your doctor.
• Try to include heart-healthy omega-3 fatty acid-containing food drinks in your daily diet. Low-fat cooking oils like olive oil, soybean oil, canola oil, and coconut oil can also help lower your elevated blood pressure.

• Do not take this drug if you are allergic to either component of the drug.
• Do not take if a patient has a tumour in the adrenal gland, has asthma or wheezing (now or in the past)
• Keep consulting with your doctor for occasional checkups  & dose adjustments.

Hypertension: It is a chronic condition when blood pressure is too high. This condition can lead to hardened arteries (blood vessels), decreasing the blood and oxygen flow to the heart. Blood pressure is the measurement of the force that our heart uses to pump blood to all parts of the body. Raised blood pressure can cause chest pain (angina) and heart attack (when the blood supply to the heart is blocked). Additionally, high blood pressure also causes brain damage (stroke) and kidney failure. You can have high blood pressure (hypertension) for years without any symptoms.