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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Jan 1, 2025 | 9:31 AM IST

Twinaqt 50/300 Tablet is used to treat HIV infection. It helps decrease the chance of developing AIDS (acquired immunodeficiency syndrome). It contains Dolutegravir and Lamivudine, which work by interfering with the working of nucleotide and nucleoside reverse transcriptase enzymes necessary for virus reproduction. Together, these help treat HIV infections. In some cases, this medication may cause side effects such as nausea, headache, tiredness, diarrhoea, dizziness, anxiety, gas, difficulty falling asleep or staying asleep, and muscle weakness.

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Manufacturer/Marketer :

Emcure Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Twinaqt 50/300 Tablet

Twinaqt 50/300 Tablet belongs to a class of drugs called antiretrovirals used to treat HIV infection. Twinaqt 50/300 Tablet helps decrease the chance of developing AIDS (acquired immunodeficiency syndrome). HIV (Human Immunodeficiency Virus) is a virus that attacks the immune system and destroys the white blood cells that help fight infection, making the individual susceptible to other infections or illnesses.

Twinaqt 50/300 Tablet contains Dolutegravir and Lamivudine. Both Dolutegravir and Lamivudine are nucleoside reverse transcriptase inhibitors. Twinaqt 50/300 Tablet works by interfering with the working of nucleotide and nucleoside reverse transcriptase enzymes necessary for virus reproduction. Together, Twinaqt 50/300 Tablet helps treat HIV infections.

Twinaqt 50/300 Tablet is a prescription medication. You should take this medicine exactly as prescribed by the doctor. The common side effects of Twinaqt 50/300 Tablet are nausea, headache, tiredness, diarrhoea, dizziness, anxiety, gas, difficulty falling asleep or staying asleep and muscle weakness. Most of these side effects of Twinaqt 50/300 Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Twinaqt 50/300 Tablet is not recommended to take Twinaqt 50/300 Tablet if you are allergic to any of its contents. Twinaqt 50/300 Tablet is not recommended for use in children and adolescents under 18 years of age. Twinaqt 50/300 Tablet may cause dizziness, so do not drive or operate heavy machinery if you feel dizzy. Consumption of alcohol may increase the risk of side effects; therefore, avoid alcohol consumption. You should not become pregnant while you are taking Twinaqt 50/300 Tablet . Talk to your doctor about effective birth control methods that you can use during your treatment. If you become pregnant while taking Twinaqt 50/300 Tablet , call your doctor immediately. You should not breastfeed if you are infected with HIV or if you are taking Twinaqt 50/300 Tablet .

Uses of Twinaqt 50/300 Tablet

Treatment of HIV infection

Medicinal Benefits

Twinaqt 50/300 Tablet is a combination of two drugs, Dolutegravir and Lamivudine, used to treat HIV infection. Both Dolutegravir and Lamivudine are nucleoside reverse transcriptase inhibitors. Twinaqt 50/300 Tablet interferes with the working of nucleotide and nucleoside reverse transcriptase enzymes necessary for virus reproduction. Thus, Twinaqt 50/300 Tablet helps treat HIV infections. Taking Twinaqt 50/300 Tablet along with practising safe sex and lifestyle changes may reduce the risk of getting or transmitting HIV to others.

Side Effects of Twinaqt 50/300 Tablet

  • Nausea
  • Headache
  • Tiredness
  • Diarrhea
  • Dizziness
  • Anxiety
  • Gas
  • Difficulty falling asleep or staying asleep
  • Muscle weakness

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Talk to your doctor about the risks and benefits of taking Twinaqt 50/300 Tablet . Before taking the Twinaqt 50/300 Tablet , inform your doctor about all your medical conditions, sensitivities, and medications you are using. Twinaqt 50/300 Tablet is not recommended for children below 18 years of age. You are advised to take proper precautions if you are infected with HIV to prevent infection from spreading to others through sexual contact or body fluids. If you have HBV and you take Twinaqt 50/300 Tablet , your condition may suddenly worsen when you stop taking Twinaqt 50/300 Tablet . Tell your doctor if you have or suspect you have hepatitis B virus infection (HBV; a continuous liver infection). Your doctor may test you to see if you have HBV before you start therapy with Twinaqt 50/300 Tablet . You are recommended to avoid alcohol consumption with Twinaqt 50/300 Tablet . Drive only if you are alert, as Twinaqt 50/300 Tablet may cause dizziness.

Therapeutic Class

ANTIRETROVIRAL AGENTS

Drug-Drug Interactions

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DolutegravirDofetilide
Critical
LamivudineEmtricitabine
Critical

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Diet & Lifestyle Advise

  • Practise safe sex by using condoms; it helps in reducing contact with semen and vaginal fluids.
  • Never share personal items that can have body fluids or blood on them, such as razor blades or toothbrushes.
  • Avoid sharing used needles, other injection or drug equipment.
  • Get tested for other sexually transmitted infections, such as gonorrhoea or syphilis, as they can make you prone to HIV infection.
  • Eat a healthy and balanced diet. Eat vitamin and nutrient-rich foods such as dark green, yellow, orange, and red vegetables and fruits as it helps to boost your immune system. Opt for lean protein and whole grains.
  • Avoid eating raw meat and eggs. Consume properly boiled and cooked meat, poultry or seafood.
  • Eat bland and low-fat foods, and avoid spicy or oily foods if you experience nausea or vomiting.
  • Try to reduce emotional and physical stress by spending time with your family or doing whatever makes you happy.

Habit Forming

No

How Twinaqt 50/300 Tablet Works

Twinaqt 50/300 Tablet contains Dolutegravir and Lamivudine. Both Dolutegravir and Lamivudine are nucleoside reverse transcriptase inhibitors. Twinaqt 50/300 Tablet works by interfering with the working of nucleotide and nucleoside reverse transcriptase enzymes necessary for virus reproduction. Together, Twinaqt 50/300 Tablet helps treat HIV infections.

What if I have taken an overdose of Twinaqt 50/300 Tablet

Never take more than the prescribed dose. If you suspect that you or someone else might have taken an overdose of Twinaqt 50/300 Tablet , go to the accident and emergency department of your local hospital at once. Do this even if there are no signs of discomfort or poisoning.
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Alcohol

Unsafe

Consumption of alcohol should be avoided.

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Pregnancy

Unsafe

Twinaqt 50/300 Tablet is not suggested during pregnancy. You should not become pregnant while you are taking Twinaqt 50/300 Tablet . Ask your doctor about effective birth control options that you can use during your therapy. If you become pregnant while taking Twinaqt 50/300 Tablet , call your doctor right away.

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Breast Feeding

Unsafe

You should not breastfeed if you are infected with HIV or if you are taking Twinaqt 50/300 Tablet .

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Driving

Caution

Twinaqt 50/300 Tablet may cause dizziness in some people. Therefore, avoid driving or operating heavy machinery if you feel dizzy after taking Twinaqt 50/300 Tablet .

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Liver

Caution

Take Twinaqt 50/300 Tablet with caution, especially if you have a history of liver diseases. Inform your doctor if you have liver impairment. Your doctor will prescribe only if the benefits outweigh the risks.

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Kidney

Caution

Take Twinaqt 50/300 Tablet with caution, especially if you have a history of Kidney diseases/conditions. Your doctor will prescribe only if the benefits outweigh the risks.

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Children

Unsafe

Twinaqt 50/300 Tablet is not recommended for children below 18 years of age.

Country of origin

India

Manufacturer/Marketer address

A €“ 504, Shapath-4, B/S Hotel Crowne Plaza, Opp. Karnavati Club, S. G. Highway ,Ahmedabad 380 051 Gujarat
Other Info - TWI0109

Author Details

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FAQs

Twinaqt 50/300 Tablet is used to treat HIV infection.
Twinaqt 50/300 Tablet contains Dolutegravir and Lamivudine. Twinaqt 50/300 Tablet works by interfering with the functioning of nucleotide and nucleoside reverse transcriptase enzymes, which are necessary for the reproduction of the virus. Together, Twinaqt 50/300 Tablet helps treat HIV infections.
Twinaqt 50/300 Tablet does not cure HIV infection. Twinaqt 50/300 Tablet reduces the amount of HIV in the body and improves the immune system's functioning.
HIV infection may still be transmitted to other persons while using Twinaqt 50/300 Tablet . Twinaqt 50/300 Tablet reduces the risk of transmission, but still, HIV infection is contagious. Therefore, discuss with a doctor regarding precautions to avoid transmission of HIV while taking Twinaqt 50/300 Tablet .
Twinaqt 50/300 Tablet may increase the risk of treatment failure. So Twinaqt 50/300 Tablet should not be stopped without consulting your doctor.
Do not stop taking Twinaqt 50/300 Tablet without consulting your doctor. Stopping Twinaqt 50/300 Tablet before treatment may worsen your hepatitis. This can occur during the first few months after you stop taking Twinaqt 50/300 Tablet . Take the Twinaqt 50/300 Tablet strictly as instructed, and do not miss any dose.

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