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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
Twigrel Combikit Tablet is used to prevent heart attack and stroke. It works by preventing platelets from adhering together and reducing the formation of harmful blood clots. This decreases the likelihood of having a heart attack or stroke. In some cases, this medicine may cause side effects like mild indigestion, nausea, headache, dizziness, and joint pain.
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Manufacturer/Marketer :

Med Manor Organics Pvt Ltd

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Twigrel Combikit Tablet

Twigrel Combikit Tablet belongs to the class of antiplatelet drugs used to prevent heart attack and stroke. A heart attack is a critical medical emergency in which the blood supply to the heart is interrupted or blocked, typically by a blood clot. Signs of a heart attack include chest discomfort or pain, pain in other parts of the body, sweating, shortness of breath, nausea, fatigue and anxiety.

Twigrel Combikit Tablet is a combination of two blood thinners: aspirin and ticagrelor. Twigrel Combikit Tablet prevents platelets from adhering together, reducing the formation of harmful blood clots. This decreases the likelihood of having a heart attack or stroke.

Twigrel Combikit Tablet should be taken after a meal or as directed by the physician. The common side effects of Twigrel Combikit Tablet include mild indigestion, nausea, headache, dizziness, and joint pain. Most of these side effects do not necessitate medical treatment and fade away with time. However, if the side effects persist, consult your doctor.

Inform your doctor if you are allergic to ticagrelor or aspirin, have kidney/liver impairment, or have bleeding problems. Let your doctor know if you are pregnant, planning to become pregnant or are a nursing mother. Do not quit taking Twigrel Combikit Tablet on your own without consulting a doctor. Stopping Twigrel Combikit Tablet may aggravate your condition and raise the risk of having a further heart attack. Twigrel Combikit Tablet may cause dizziness, so drive only if you are alert.

Uses of Twigrel Combikit Tablet

Prevention of heart attack or stroke.

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Twigrel Combikit Tablet belongs to the class of medication called antiplatelet agents used to prevent heart attack and stroke. Twigrel Combikit Tablet contains two blood thinners: aspirin and ticagrelor. Twigrel Combikit Tablet prevents platelets from aggregation, thereby minimising the formation of harmful blood clots. This lowers the chances of having a heart attack or stroke.

How Twigrel Combikit Tablet Works

Twigrel Combikit Tablet is a combination of two blood thinners: aspirin and ticagrelor. Twigrel Combikit Tablet prevents platelets from adhering together, reducing the formation of harmful blood clots. This decreases the likelihood of having a heart attack or stroke.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Twigrel Combikit Tablet

  • Mild indigestion
  • Pain and swelling in the joints
  • Headache
  • Dizziness
  • Nausea
  • Diarrhoea
  • Constipation
  • Mild rash

What if I have taken an overdose of Twigrel Combikit Tablet

Take Twigrel Combikit Tablet only as prescribed by the physician. Do not exceed the recommended dose, as it might cause an overdose. If you suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

Inform your doctor if you are allergic to ticagrelor or aspirin, have kidney/liver impairment, or have bleeding problems. Let your doctor know if you are pregnant, planning to become pregnant or are a nursing mother. Do not quit taking Twigrel Combikit Tablet on your own without consulting a doctor. Stopping Twigrel Combikit Tablet may aggravate your condition and raise the risk of having a further heart attack. Twigrel Combikit Tablet may cause dizziness, so drive only if you are alert. Before taking Twigrel Combikit Tablet , inform your doctor about your medical history and other medications you are currently taking to rule out any potential negative effects.

Drug-Drug Interactions

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TicagrelorVoriconazole
Critical
TicagrelorIndinavir
Critical

Drug-Drug Interactions

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TicagrelorVoriconazole
Critical
How does the drug interact with Twigrel Combikit Tablet 21's:
Using Twigrel Combikit Tablet 21's together with Voriconazole can significantly increase the blood levels of Twigrel Combikit Tablet 21's.

How to manage the interaction:
Taking Twigrel Combikit Tablet 21's with Voriconazole is not recommended, but it can be taken together if prescribed by a doctor. However, consult a doctor if you experience vomiting, headache, dizziness, or weakness. Do not discontinue any medications without consulting a doctor.
TicagrelorIndinavir
Critical
How does the drug interact with Twigrel Combikit Tablet 21's:
Using Twigrel Combikit Tablet 21's together with indinavir can cause risk of bleeding.

How to manage the interaction:
Taking Twigrel Combikit Tablet 21's with Indinavir is not recommended, but it can be taken together if prescribed by a doctor. However, consult a doctor if you experience any unusual bleeding or bruising, swelling, vomiting, blood in your urine or stools, headache, dizziness, or weakness. Do not discontinue any medications without consulting a doctor.
TicagrelorPosaconazole
Critical
How does the drug interact with Twigrel Combikit Tablet 21's:
Co-administration of posaconazole with Twigrel Combikit Tablet 21's can increase the risk of bleeding.

How to manage the interaction:
Taking Twigrel Combikit Tablet 21's with Posaconazole is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience any unusual bleeding or bruising, swelling, vomiting, blood in your urine or stools, headache, dizziness, or weakness. Do not discontinue any medications without consulting a doctor.
TicagrelorMifepristone
Critical
How does the drug interact with Twigrel Combikit Tablet 21's:
Co-administration of Mifepristone with Twigrel Combikit Tablet 21's can increase the risk of vaginal bleeding in women.

How to manage the interaction:
Taking Twigrel Combikit Tablet 21's with Mifepristone is not recommended, but can be taken together if prescribed by a doctor. However, consult your doctor if you experience any symptoms like heavy period bleed for more than 7 days, weakness, tiredness, shortness of breath or paleness. Do not discontinue any medications without consulting a doctor.
TicagrelorRitonavir
Critical
How does the drug interact with Twigrel Combikit Tablet 21's:
Taking Twigrel Combikit Tablet 21's with Ritonavir may significantly increase the blood levels of Twigrel Combikit Tablet 21's.

How to manage the interaction:
Taking Twigrel Combikit Tablet 21's with Ritonavir is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience any unusual bleeding or bruising, swelling, vomiting, blood in your urine or stools, headache, dizziness, or weakness. Do not discontinue any medications without consulting a doctor.
TicagrelorConivaptan
Critical
How does the drug interact with Twigrel Combikit Tablet 21's:
Co-administration of Twigrel Combikit Tablet 21's with Conivaptan can increase the risk of bleeding.

How to manage the interaction:
Taking Twigrel Combikit Tablet 21's with Conivaptan is not recommended, please consult your doctor before taking it. However, if you experience unusual bleeding or bruising, swelling, vomiting, blood in your urine or stools, headache, dizziness, or weakness contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
TicagrelorTelithromycin
Critical
How does the drug interact with Twigrel Combikit Tablet 21's:
Using Twigrel Combikit Tablet 21's together with telithromycin cause increase the blood levels of Twigrel Combikit Tablet 21's.

How to manage the interaction:
Taking Twigrel Combikit Tablet 21's with Telithromycin is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience any unusual bleeding or bruising, swelling, vomiting, blood in your urine or stools, headache, dizziness, or weakness. Do not discontinue any medications without consulting a doctor.
TicagrelorItraconazole
Critical
How does the drug interact with Twigrel Combikit Tablet 21's:
The blood levels and effects of Twigrel Combikit Tablet 21's may be greatly increased when combined with itraconazole.

How to manage the interaction:
Itraconazole and Twigrel Combikit Tablet 21's may interact, however if prescribed by a physician, they can be used together. While receiving therapy, you should consult a doctor if you develop any unusual bleeding or bruising, swelling, vomiting, blood in your urine or stools, headache, dizziness, or weakness. Without consulting a doctor, never stop taking any medication.
TicagrelorKetoconazole
Critical
How does the drug interact with Twigrel Combikit Tablet 21's:
Co-administration of Twigrel Combikit Tablet 21's with ketoconazole can cause severe bleeding.

How to manage the interaction:
Taking Twigrel Combikit Tablet 21's with Ketoconazole is not recommended as it can cause an interaction, it can be taken if prescribed by the doctor. However, if you experience any unusual bleeding or bruising, swelling, vomiting, blood in your urine or stools, headache, dizziness, or weakness, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
AspirinKetorolac
Critical
How does the drug interact with Twigrel Combikit Tablet 21's:
Co-administration of Ketorolac and Twigrel Combikit Tablet 21's may increase the risk of side effects.

How to manage the interaction:
Taking Ketorolac with Twigrel Combikit Tablet 21's is not recommended but can be taken together if prescribed by a doctor. However, consult a doctor if you experience unusual bleeding or bruising, dizziness, tarry stools, coughing up or vomiting fresh or dried blood, severe headache and weakness. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat at regular intervals and have a nutritious diet rich in fresh fruits and vegetables.
  • Limit your alcohol consumption because it elevates blood pressure and increases the risk of heart disease.
  • Maintain a healthy weight and exercise routine to keep your heart healthy.
  • Your doctor will also teach you how to recognise and manage the early symptoms of heart disease.
  • Losing weight and maintaining a healthy BMI are critical for improving cardiac health.
  • Thirty minutes of daily physical activity can help avoid heart disease.
  • To improve your cardiac health, quit smoking.
  • Stress reduction is critical for maintaining a healthy heart. Yoga and meditation can help relax your thoughts.

Habit Forming

No

Therapeutic Class

PLATELET AGGREGATION INHIBITOR

Twigrel Combikit Tablet Substitute

Substitutes safety advice
  • Ticastro-AS Combikit (14 + 7 Tablet)

    16.78per tablet
  • Ticabid-A Combikit Tablet 21's

    13.89per tablet
  • Tiare Kit 1's

    310.10per tablet
  • Vasoglor A Kit Tablet 1's

    by AYUR

    320.90per tablet
  • Xygrel-AS Combikit 1's

    by AYUR

    352.40per tablet
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Alcohol

Caution

Avoid consumption of alcohol as it may increase dizziness.

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Pregnancy

Caution

It is not advised to use Twigrel Combikit Tablet when pregnant. Please consult a doctor, your doctor may prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Twigrel Combikit Tablet should be used in nursing mothers only if clinically needed, and the benefits outweigh the risks. Please consult the doctor.

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Driving

Caution

Twigrel Combikit Tablet may cause drowsiness and dizziness, so drive or operate machinery only if you are alert.

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Liver

Caution

Caution should be exercised while using Twigrel Combikit Tablet in patients suffering from liver impairment. Please consult a doctor. Your doctor will prescribe only if the benefits outweigh the risks.

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Kidney

Caution

Caution should be exercised while using Twigrel Combikit Tablet in patients suffering from kidney impairment. Please consult a doctor. Your doctor will prescribe only if the benefits outweigh the risks.

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Children

Caution

The safety and efficacy of Twigrel Combikit Tablet in children have not been demonstrated. For further information, please contact your doctor.

FAQs

Twigrel Combikit Tablet is used to prevent heart attack and stroke.
Twigrel Combikit Tablet prevents platelets from aggregating, thereby minimising the formation of dangerous blood clots. This lowers the chances of having a heart attack or stroke.
Twigrel Combikit Tablet may increase the risk of bleeding. Exercise caution when performing daily tasks such as shaving, cutting fingernails, or using sharp instruments. Inform your doctor if you are due to undergo any surgical procedure.
Yes, you can get vaccinated while on Twigrel Combikit Tablet . However, it would be better to tell your doctor or nurse that you're taking an antiplatelet medication.
Do not discontinue Twigrel Combikit Tablet without consulting your doctor. Stopping Twigrel Combikit Tablet may aggravate your condition and raise the risk of having a further heart attack or stroke.
Avoid consuming grapefruit or grapefruit juice while taking Twigrel Combikit Tablet since it may increase the effectiveness of Twigrel Combikit Tablet . This elevates the chances of bleeding more easily.
You are recommended to avoid alcohol, grapefruit juice, and medications like apixaban or other anticoagulants while taking Twigrel Combikit Tablet , as they increase bleeding risk. If you still have any concerns, discuss with your doctor.
Use of Twigrel Combikit Tablet during menstruation may increase the risk of heavier or prolonged bleeding due to its blood-thinning effects. Therefore, please take your doctor’s advice before taking Twigrel Combikit Tablet .
Yes, blood thinners may cause shortness of breath, which can sometimes indicate a serious condition like a heart attack. If you experience sudden or worsening shortness of breath or any unusual symptom, seek immediate medical attention.
Brilinta 90 contains only ticagrelor, while Twigrel Combikit Tablet is a combination of two components as aspirin and ticagrelor used to prevent blood clots.
Your doctor decides the best time to take Twigrel Combikit Tablet . Take it with or without food as advised. Follow your doctor's instructions regarding the timing and dosage for effective results.
Twigrel Combikit Tablet causes side effects such as mild indigestion, pain and swelling in the joints, headache, dizziness, nausea, diarrhoea, constipation, and mild rash. However, please consult a doctor if these persist for longer durations.

Country of origin

India

Manufacturer/Marketer address

16-11-477/45, Dilsukh Nagar, Hyderabad-500036, Telangana, India.
Other Info - TWI0106

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