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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 22, 2024 | 7:37 PM IST
Tval CR 300 Tablet is used to treat epilepsy/seizures/fits. Additionally, it is also used to treat mood disorders and migraine. It contains Sodium valproate and Valproic acid, which works by decreasing the excessive and abnormal nerve activity in the brain. Thereby, it helps in controlling seizures. It blocks the nerve transmission across the brain and provides a calming effect. In some cases, it may cause common side effects such as headache, sleepiness, drowsiness, impaired coordination, apathy (lack of interest), irregular periods and weight gain. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Manufacturer/Marketer

Tripada Biotec Pvt Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Tval CR 300 Tablet

Tval CR 300 Tablet belongs to a group of medicines called 'anticonvulsants' or 'anti-epileptics' primarily used to treat epilepsy/seizures/fits. Additionally, Tval CR 300 Tablet is also used to treat mood disorders and migraine. Epilepsy is a sudden rush of electricity in the brain. In patients with seizures, the typical brain electrical pattern is disrupted by sudden bursts of electrical impulses that affect an individual's consciousness, movements or sensations.
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Tval CR 300 Tablet is a combination of two drugs, namely: Sodium valproate and Valproic acid. Tval CR 300 Tablet works by decreasing the excessive and abnormal nerve activity in the brain. Thereby helps in controlling seizures. Tval CR 300 Tablet increases the amount of a chemical substance called GABA, this helps block the nerve transmission across the brain and provides a calming effect.
 
You are advised to take Tval CR 300 Tablet for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side effects such as headache, sleepiness, drowsiness, impaired coordination, apathy (lack of interest), irregular periods and weight gain. Talk to your doctor if you experience these side effects persistently.
 
Do not take Tval CR 300 Tablet if you are pregnant, as it could cause serious congenital disabilities. If you are of childbearing age, use effective contraception while taking Tval CR 300 Tablet . Consult your doctor before taking Tval CR 300 Tablet if you are breastfeeding. Tval CR 300 Tablet causes drowsiness and dizziness, so avoid driving unless you are alert. Avoid consuming alcohol along with Tval CR 300 Tablet as it could lead to an increased risk of seizures. Care should be taken while giving Tval CR 300 Tablet to children below 3 years as there is a higher risk of liver intoxication during the first 6 months of treatment.

Uses of Tval CR 300 Tablet

Treatment of Epilepsy, Mood disorder, Migraine.

Medicinal Benefits

Tval CR 300 Tablet is a combination of two drugs, namely: Sodium valproate and Valproic acid. Tval CR 300 Tablet is used to treat epilepsy/seizures/fits, mood disorders and to prevent migraine headaches. Tval CR 300 Tablet decreases the excessive and abnormal nerve activity in the brain, thereby controlling seizures. Tval CR 300 Tablet is used to treat certain forms of epilepsy, such as petit mal epilepsy (short-term unconsciousness due to a disorder in the brain), myoclonic seizures (sudden muscle contractions) and grand mal epilepsy (severe muscle contractions which lead to unconsciousness). Tval CR 300 Tablet may also be used to treat epilepsy, which does not sufficiently respond to other anticonvulsant drugs, such as epilepsy, which is not associated with movements and epilepsy, with symptoms affecting perception and deliberate movements. Tval CR 300 Tablet is used to treat both partial seizures (affects only a part of the brain) and generalised seizures (affects the entire brain).

Directions for Use

Take Tval CR 300 Tablet with or 1 hour prior to food. Swallow Tval CR 300 Tablet a whole with a glass of water; do not chew or break it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Tval CR 300 Tablet

  • Headache
  • Nausea
  • Vomiting
  • Diarrhoea
  • Sleepiness
  • Drowsiness
  • Impaired coordination
  • Apathy (lack of interest)
  • Hair loss
  • Irregular periods
  • Weight gain

Drug Warnings

Do not take Tval CR 300 Tablet if you are allergic to any of its contents, if you have/ had liver problems, porphyria (blood disorder) or if you are susceptible to bleeding. Inform your doctor if you have inflammation-like diseases, bone marrow damage or kidney problems. Talk to your doctor if you experience weakness, loss of appetite, lack of interest, recurrence or worsening of seizures, prolonged bleeding or abdominal pain while taking Tval CR 300 Tablet . Consult your doctor immediately if you experience suicidal tendencies while taking Tval CR 300 Tablet . Please do not stop taking Tval CR 300 Tablet without consulting your doctor to avoid the worsening of seizures. Do not take Tval CR 300 Tablet if you are pregnant, as it could cause serious birth defects. If you are of child-bearing age, use effective contraception while taking Tval CR 300 Tablet . Consult your doctor before taking Tval CR 300 Tablet if you are breastfeeding. Tval CR 300 Tablet causes drowsiness and dizziness, so avoid driving unless you are alert. Avoid consuming alcohol along with Tval CR 300 Tablet as it could lead to increased risk of seizures. Care should be taken while giving Tval CR 300 Tablet to children below 3 years as there is a higher risk of liver intoxication during the first 6 months of treatment.

Drug Interactions

Drug-Drug Interactions: Tval CR 300 Tablet may interact with pain killers (aspirin), anti-epileptics (phenobarbital, primidone, phenytoin, carbamazepine, lamotrigine, felbamate), anti-HIV (zidovudine), anti-depressant (amitriptyline, sertraline), anti-psychotic (quetiapine, olanzapine, risperidone), hormone (levonorgestrel), anti-malarial (mefloquine), antacid (cimetidine), antibiotics (imipenem, meropenem, erythromycin), bile-acid sequestrant (cholestyramine), benzodiazepine (clonazepam, diazepam).

Drug-Food Interactions: Avoid alcohol consumption while taking Tval CR 300 Tablet as it might cause increased dizziness and sleepiness. Alcohol intake might also provoke seizures.

Drug-Disease Interactions: Inform your doctor if you have depression, liver disease, urea cycle disorders, suicidal tendencies, HIV disease, and thrombocytopenia (low levels of platelets).

Drug-Drug Interactions Checker List

  • ASPIRIN
  • PHENOBARBITAL
  • PHENYTOIN
  • PRIMIDONE
  • CARBAMAZEPINE
  • LAMOTRIGINE
  • FELBAMATE
  • ZIDOVUDINE
  • AMITRIPTYLINE
  • SERTRALINE
  • QUETIAPINE
  • OLANZAPINE
  • RISPERIDONE
  • LEVONORGESTREL
  • MEFLOQUINE
  • CIMETIDINE
  • IMIPENEM
  • MEROPENEM
  • ERYTHROMYCIN
  • CHOLESTYRAMINE
  • CLONAZEPAM
  • DIAZEPAM

Habit Forming

No

Diet & Lifestyle Advise

  • A ketogenic diet (low in carbohydrates and high in fats) is recommended for children with epilepsy. This diet helps in utilising fat instead of glucose for the generation of energy.

  • Atkins diet (high fat and controlled carbohydrates) is recommended for adolescents and adults.

  • Exercising regularly helps in maintaining weight and improving overall health. 

  • Rest well, and get plenty of sleep.

  • Avoid smoking and alcohol consumption.

  • Meditation and yoga can help lower stress, decrease pain sensitivity and improves coping skills.

  • Have a seizure response plan; this helps those around you know what to do.

  • Prepare your living area; small changes may help in reducing the risk of physical injury during a seizure.

  • Understand what triggers seizures and try reducing or avoiding them.

  • Please pay attention to overall health as it can help in reducing seizure activity.

  • Install an alarm or emergency device to get assistance during a seizure attack.

Special Advise

  • Regular monitoring of blood count is advised while taking Tval CR 300 Tablet as it may cause spontaneous bleeding or bruising.

  • Inform your doctor that you are taking Tval CR 300 Tablet if you are due to have any surgery or dental intervention.

  • Consult your doctor if you experience irregular periods while taking Tval CR 300 Tablet .

  • If you are of child-bearing age, use effective contraception while taking Tval CR 300 Tablet .

Disease/Condition Glossary

Epilepsy/Seizures: Seizures, also known as fits or convulsions, is a single occurrence of abnormal electrical activity in the brain, whereas epilepsy is a chronic neurological disorder characterized by recurrent seizures. The possible causes of epilepsy include traumatic brain injury, scarring on the brain after a brain injury, high fever, stroke, vascular diseases, lack of oxygen to the brain, brain tumours, and genetic disorders. Symptoms include mood changes, anxiousness, nausea, dizziness, weakness, headache, muscle jerking, spasms, loss of balance, teeth clenching, rapid blinking or eye movements, biting the tongue, confusion, and loss of consciousness.

Mood disorder: It is a mental health disorder which mainly affects a person's emotional state. A mood disorder is associated with episodes of mood swings ranging from manic highs to depressive lows. 

Migraine: Migraine is a neurological condition which is characterised by an intense, debilitating headache. Hormonal changes, stress, lack or excess of sleep, bright lights, loud sounds, and certain foods and drinks can trigger migraine headaches. Symptoms of migraine include throbbing pain in one particular area with varying intensity, nausea, vomiting, numbness or tingling sensation, difficulty speaking, and sensitivity to sound and light. 

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Alcohol

Unsafe

Avoid consumption of alcohol while taking Tval CR 300 Tablet as it may increase the risk of seizures.

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Pregnancy

Unsafe

Tval CR 300 Tablet belongs to pregnancy category D. Avoid taking Tval CR 300 Tablet if you are pregnant unless prescribed by a doctor, as it could lead to serious birth defects.

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Breast Feeding

Caution

Tval CR 300 Tablet may pass into breastmilk. Consult your doctor before taking Tval CR 300 Tablet if you are breastfeeding.

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Driving

Unsafe

Tval CR 300 Tablet causes dizziness, sleepiness and drowsiness. Do not drive or operate machinery unless you are alert.

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Liver

Unsafe

Tval CR 300 Tablet should not be used if you have liver problems or your family has a history of liver problems. Please consult your doctor if you have any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Caution

Tval CR 300 Tablet can be given to children if prescribed by the doctor. The dose will be adjusted by the doctor depending upon the child's body weight.

Country of origin

India

Manufacturer/Marketer address

3 Yogi Complex, Nr Doordarshan, Kendra, Thaltej, Ahmedabad, India 380054.
Other Info - TVA0002

Author Details

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FAQs

Tval CR 300 Tablet is primarily used to treat epilepsy/seizures/fits. It is also used to treat mood disorders and migraine.
Tval CR 300 Tablet decreases the excessive and abnormal nerve activity in the brain. Tval CR 300 Tablet increases the amount of a chemical substance called GABA, this helps in blocking the nerve transmission across the brain and provides a calming effect. Thereby helps in controlling seizures.
Do not discontinue Tval CR 300 Tablet without consulting your doctor. To treat your condition effectually, continue taking Tval CR 300 Tablet for as long as prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking Tval CR 300 Tablet ; your doctor will reduce the dose gradually to avoid worsening of seizures.
Tval CR 300 Tablet may cause thrombocytopenia (low levels of platelets). This might increase the risk of bleeding and bruising. Be cautious while using sharp objects. Consult your doctor if you notice unexplained bleeding or bruising.
Tval CR 300 Tablet may cause weight gain due to an increase in appetite. Maintain a healthy weight by following a proper diet and exercising regularly.
Tval CR 300 Tablet may increase the effect of aspirin when taken together. Please consult your doctor before taking Tval CR 300 Tablet with aspirin to avoid unpleasant side-effects. Tval CR 300 Tablet and aspirin should not be given together to children below 3 years as it could lead to liver intoxication.
Tval CR 300 Tablet contains sodium valproate and valproic acid as the active ingredients. It is used for the treatment of all types of epilepsy.
Take Tval CR 300 Tablet with or after food as advised by your doctor.
You are recommended to avoid consumption of alcohol while taking Tval CR 300 Tablet as it may increase the risk of seizures.
No, Tval CR 300 Tablet does not cause addiction. However, it should be taken as per dose and duration prescribed by your doctor. Avoid self-medication as it may have severe unwanted effects.
Tval CR 300 Tablet does not cure epilepsy, it only prevents the seizures from occurring. Therefore, you may need to continue taking it for years. If you experience any problems while taking Tval CR 300 Tablet , please consult your doctor.
You are recommended not to stop taking Tval CR 300 Tablet suddenly as it may increase the chances of recurrence of seizures. Therefore, it should be discontinued gradually. If you feel the need to stop taking Tval CR 300 Tablet , always consult your doctor.
Yes, Tval CR 300 Tablet may cause weight gain. To control your weight, you should eat a healthy balanced diet and exercise regularly. If you have any other concerns, consult your doctor.
Yes, Tval CR 300 Tablet has no influence on the working of birth control pills. However, contraceptives (birth control pills) may interfere with the working of Tval CR 300 Tablet and seizures may occur. Thus, it is essential to inform your doctor if you are using birth control pills. Your doctor will monitor your response to the treatment and Tval CR 300 Tablet levels in your blood.
Long term use of Tval CR 300 Tablet is safe for large number of patients. Rarely, using Tval CR 300 Tablet for long term may weaken your bones, thereby increasing their chances of breaking easily (osteopenia and osteoporosis). Get regular check-ups done for bone health if you are taking Tval CR 300 Tablet for a prolonged time.
Tval CR 300 Tablet may cause change of hair colour, thinning of hair, and even hair loss. If you have any concerns, discuss with your doctor if it is possible to reduce the dose of Tval CR 300 Tablet . Your hair may regrow after either switching to a different medicine or reducing your dose.
Tval CR 300 Tablet may cause side effects such as nausea, diarrhoea, hair loss, weight gain, headache and irregular periods. If these side effects persist or worsen, please consult your doctor.
You are recommended to avoid taking Tval CR 300 Tablet if you have known hypersensitivity to valproic acid, have liver disease, or are pregnant. It should be used with caution in kidney impairment patients.
Tval CR 300 Tablet overdose can cause serious symptoms such as metabolic acidosis and deep coma. If you suspect you have taken overdose of Tval CR 300 Tablet , seek medical help immediately.

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