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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Trypace Tablet is used to relieve pain and inflammation associated with osteoarthritis, rheumatoid arthritis, spondylosis, spondyloarthritis, and ortho-degenerative disorders. It works by blocking the action of chemical messengers that cause pain and inflammation. Besides this, it helps reduce swelling and inflammation by breaking down the abnormal proteins at the site of inflammation.
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Manufacturer/Marketer :

Alonsoa Life Sciences

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Trypace Tablet

Trypace Tablet is a combination medicine used to relieve pain and inflammation associated with osteoarthritis, rheumatoid arthritis, spondylosis, spondyloarthritis, and ortho-degenerative disorders. Pain is a symptom triggered by the nervous system, causing uncomfortable sensations in the body. Arthritis, also known as joint inflammation, is the tenderness and swelling of the joints. Symptoms include swelling, pain, and stiffness. 
 
Trypace Tablet is a combination of three drugs, namely: Aceclofenac, Paracetamol, and Trypsin chymotrypsin. Aceclofenac and Paracetamol work by blocking the effect of chemical messengers called prostaglandins by inhibiting cyclooxygenase (COX) enzymes, thereby reduces mild to moderate pain and inflammation at the injured or damaged site. Trypsin chymotrypsin breaks down the abnormal proteins at the site of inflammation, thereby reduces swelling and inflammation.
 
You are advised to take Trypace Tablet for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side-effects such as nausea, vomiting, stomach pain, loss of appetite, indigestion, and diarrhoea. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
 
Consult your doctor if you are pregnant or breastfeeding. Trypace Tablet may cause drowsiness and dizziness, so drive with caution. Trypace Tablet is not recommended for children as safety and efficacy have not been established. Avoid consuming alcohol with Trypace Tablet as it could lead to increased drowsiness and dizziness; it might also increase the risk of stomach bleeding. Keep your doctor informed about your health condition and medicines to rule out any side effects/interactions.

Uses of Trypace Tablet

Treatment of Pain and inflammation associated with musculoskeletal and joint disorders.

Directions for Use

Take Trypace Tablet with food to prevent stomach upset. Swallow Trypace Tablet as a whole with a glass of water; do not chew or break it.

Medicinal Benefits

Trypace Tablet is a combination of three drugs, namely: Aceclofenac, Paracetamol, and Trypsin chymotrypsin. Trypace Tablet is used to relieve pain and inflammation associated with osteoarthritis, rheumatoid arthritis, spondylosis, spondyloarthritis, and ortho-degenerative disorders. Aceclofenac is an NSAID (Non-Steroidal Anti-Inflammatory Drug) and Paracetamol is an analgesic. Aceclofenac and Paracetamol work by blocking the effect of chemical messengers called prostaglandins by inhibiting cyclooxygenase (COX) enzymes, thereby reducing mild to moderate pain and inflammation at the injured or damaged site. Trypsin chymotrypsin is a combination of enzymes that breaks down the abnormal proteins at the site of inflammation, thereby reducing swelling and inflammation by increasing the blood supply at the affected area.

How Trypace Tablet Works

Trypace Tablet is a combination of three drugs, namely: Aceclofenac, Paracetamol, and Trypsin chymotrypsin. Aceclofenac and Paracetamol work by blocking the effect of chemical messengers called prostaglandins by inhibiting cyclooxygenase (COX) enzymes, thereby reduces mild to moderate pain and inflammation at the injured or damaged site. Trypsin chymotrypsin breaks down the abnormal proteins at the site of inflammation, thereby reduces swelling and inflammation.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Trypace Tablet

  • Nausea
  • Vomiting
  • Stomach pain
  • Diarrhoea
  • Indigestion
  • Loss of appetite
  • Heartburn

What if I have taken an overdose of Trypace Tablet

Take Trypace Tablet only as prescribed by the physician. Do not exceed the recommended dose, as it might cause an overdose. If you suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

Do not take Trypace Tablet if you are allergic to any of its contents; if you have/had severe heart problems, active or recurring peptic ulcer, gastrointestinal perforation, bleeding problems, inflammation of intestines, severe liver or kidney impairment. Inform your doctor if you have/had high blood pressure, heart problems, high cholesterol, diabetes, asthma, angina, bowel problems, blood clotting disorder, a habit of smoking, liver or kidney problems. Consult your doctor if you are pregnant or breastfeeding. Stop taking Trypace Tablet and consult your doctor immediately if you have stomach pain or any signs of bleeding in the intestine or stomach, such as blood in stools. 

Drug-Drug Interactions

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AceclofenacAtenolol
Severe
ParacetamolMipomersen
Severe

Drug-Drug Interactions

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AceclofenacAtenolol
Severe
How does the drug interact with Trypace Tablet 10's:
Co-administration of Atenolol with Trypace Tablet 10's could increase the risk of low blood pressure.

How to manage the interaction:
Although there is a possible interaction between Atenolol and Trypace Tablet 10's, you can take these medicines together if prescribed by a doctor. Consult a doctor if you experience excessive sweating, shortness of breath, palpitations, or chest discomfort. Do not discontinue any medications without consulting a doctor.
ParacetamolMipomersen
Severe
How does the drug interact with Trypace Tablet 10's:
Co-administration of Mipomersen with Trypace Tablet 10's may increase the risk or severity of liver injury.

How to manage the interaction:
There may be a possibility of interaction between Trypace Tablet 10's and Mipomersen, but it can be taken if prescribed by a doctor. Do not stop using any medications without talking to a doctor.
ParacetamolValdecoxib
Severe
How does the drug interact with Trypace Tablet 10's:
Co-administration of Trypace Tablet 10's and Valdecoxib may increase the risk or severity of adverse effects.

How to manage the interaction:
Although there is a possible interaction between Trypace Tablet 10's and Valdecoxib, you can take these medicines together if prescribed by a doctor. However, if the side effects worsen, please consult a doctor.
ParacetamolOxazepam
Severe
How does the drug interact with Trypace Tablet 10's:
Co-administration of Trypace Tablet 10's may decrease the excretion rate of Oxazepam which could result in a higher serum level.

How to manage the interaction:
Although there is a possible interaction between Oxazepam and Trypace Tablet 10's, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without a doctor's advice.
ParacetamolLomitapide
Severe
How does the drug interact with Trypace Tablet 10's:
Co-administration of Lomitapide and Trypace Tablet 10's may increase the risk of severity of liver injury.

How to manage the interaction:
Although there is a possible interaction between Trypace Tablet 10's and Lomitapide, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without a doctor's advice.
ParacetamolKetoconazole
Severe
How does the drug interact with Trypace Tablet 10's:
Co-administration of Trypace Tablet 10's and Ketoconazole may increase the risk of liver injury.

How to manage the interaction:
Although there is a possible interaction between Trypace Tablet 10's and Ketoconazole, you can take these medicines together if prescribed by a doctor. However, if you have joint pain or swelling, fever, chills, unusual bleeding or bruising, skin rash, itching, over-tiredness, nausea, vomiting, loss of appetite, stomach pain, dark-colored urine, light-colored stools, and/or yellowing of the skin or eyes, contact a doctor immediately as these may be signs and symptoms of liver damage. Do not discontinue the medication without consulting a doctor.
ParacetamolTeriflunomide
Severe
How does the drug interact with Trypace Tablet 10's:
Co-administration of Teriflunomide with Trypace Tablet 10's may increase the risk or severity of Liver problems.

How to manage the interaction:
Taking Trypace Tablet 10's with Teriflunomide together can possibly result in an interaction, but it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
ParacetamolKetamine
Severe
How does the drug interact with Trypace Tablet 10's:
Co-administration of ketamine and Trypace Tablet 10's may decrease the effectiveness of Ketamine which could result in a higher blood level.

How to manage the interaction:
Although taking Ketamine and Trypace Tablet 10's together can evidently cause an interaction, it can be taken if a doctor has suggested it. If you're feeling very sleepy or having trouble breathing, it's important to contact your doctor right away. Do not stop using any medications without a doctor's advice.
ParacetamolLeflunomide
Severe
How does the drug interact with Trypace Tablet 10's:
Co-administration of Trypace Tablet 10's and Leflunomide may increase the risk of liver problems.

How to manage the interaction:
Although there is a possible interaction between Trypace Tablet 10's and Leflunomide, they can be taken together if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, or yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Physical activity helps in strengthening muscles and relieves joint stiffness. Gentle activities like 20-30minutes of walking or swimming would be helpful.
  • Performing yoga may also help in improving joint flexibility and pain management.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • Get adequate sleep, as resting the muscles can help in reducing inflammation and swelling.
  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
  • Acupuncture, massage and physical therapy may also be helpful.
  • Eat food rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.
  • Foods containing flavonoids help in reducing inflammation. These include soy, berries, broccoli, grapes and green tea.
  • Avoid smoking and alcohol consumption.

Habit Forming

No

Therapeutic Class

ANALGESICS

Trypace Tablet Substitute

Substitutes safety advice
  • Zerodol TC Tablet 10's

    15.35per tablet
  • Chymonac Tablet 10's

    17.42per tablet
  • Rockheal Tablet 10's

    18.90per tablet
  • Chymomax Tablet 10's

    by AYUR

    14.31per tablet
  • Ziffinac-TC Tablet 10's

    18.90per tablet
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Alcohol

Unsafe

Avoid consumption of alcohol while taking Trypace Tablet as it may increase drowsiness. It may also increase the risk of stomach bleeding.

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Pregnancy

Caution

Please consult your doctor if you have any concerns; your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Consult your doctor if you are breastfeeding; your doctor will decide whether Trypace Tablet can be taken by breastfeeding mothers or not.

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Driving

Caution

Trypace Tablet may cause dizziness and drowsiness. Do not drive or operate machinery unless you are alert.

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Liver

Caution

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this. Trypace Tablet is not recommended for patients with severe hepatic impairment.

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Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this. Trypace Tablet is not recommended for patients with severe renal impairment.

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Children

Unsafe

Trypace Tablet is not recommended for children as safety and effectiveness have not been established.

FAQs

Trypace Tablet is used to relieve pain and inflammation associated with musculoskeletal and joint disorders.
Trypace Tablet contains Aceclofenac, Paracetamol, and Trypsin chymotrypsin. Aceclofenac and Paracetamol work by blocking the effect of chemical messengers that cause pain and inflammation. Trypsin chymotrypsin breaks down the abnormal proteins at the site of inflammation, thereby reducing swelling and inflammation.
Trypace Tablet is used to reduce and relieve pain and inflammation associated with osteoarthritis, rheumatoid arthritis, spondylosis, spondyloarthritis, and ortho-degenerative disorders. Arthritis is tenderness and swelling in the joints.
Do not take any other medicines for pain relief such as NSAIDs along with Trypace Tablet unless prescribed by the doctor as it might increase the risk of side effects.
Avoid exceeding the dose and duration advised by the doctor. Taking more than the daily dose of Trypace Tablet might cause serious liver damage or allergic reactions like rash, difficulty in breathing, and swelling of the face, throat, and mouth. Therefore, Trypace Tablet should not be taken for longer durations unless prescribed by the doctor.
Avoid taking Trypace Tablet if you have ulcers in the stomach or intestines, bleeding problems, or heart problems. Talk to your doctor if you have any concerns.
Please consult your doctor if are pregnant or planning pregnancy before taking Trypace Tablet . Your doctor will prescribe Trypace Tablet only if the benefits outweigh the risks.
Trypace Tablet should be taken as advised by the doctor. It is preferably taken with food to avoid stomach upset.
Yes, Trypace Tablet is a painkiller as well as anti-inflammatory drug. It contains aceclofenac and paracetamol which possess pain relieving action.
Trypace Tablet should be avoided by patients with severe kidney or liver problems. Also, inform your doctor if you have heart-related diseases, hypertension (high blood pressure) or bleeding disorder, etc.
Trypace Tablet may cause side effects such as nausea, vomiting, stomach pain, diarrhoea, loss of appetite, indigestion and heartburn. If these side effects persist or worsen, please consult your doctor.
Trypace Tablet may be used or recommended to provide relief from tooth pain and swelling after a tooth extraction. However, do not self-medicate as it may cause unwanted side effects.
No, there are no reports of Trypace Tablet addiction in patients.
Trypace Tablet should be continued for as long as it is advised by your doctor. It can be discontinued if you are using it for short-term when your pain is relieved.
Yes, the use of Trypace Tablet can cause dizziness (feeling faint, lightheaded, weak, or unsteady) in some patients. If you experience dizziness or lightheadedness, it is best to take rest for some time and resume once you feel better.
Yes, the long-term use of Trypace Tablet can cause damage to the kidneys. Normal kidneys produce prostaglandins, a chemical that protects them from damage. Long term use of painkillers lowers the prostaglandins levels in the body leading to kidney damage. Therefore, painkillers are not recommended to patients with underlying kidney disease.
Trypace Tablet contains Paracetamol, which is known to harm the liver especially when taken in more than recommended doses. Also, avoid alcohol consumption while taking Trypace Tablet , as it may further increase the risk of liver damage. Also, Trypace Tablet is preferably avoided in patients with underlying liver disease. If you notice any early signs and symptoms of liver damage such as yellow skin or eyes, dark urine, fever, stomach pain, nausea, vomiting, loss of appetite, rash, fatigue (overtiredness) and abnormal liver enzymes, contact your doctor immediately.
It may take about an hour to experience the first benefit of pain relief after taking Trypace Tablet .
If you forget to take a dose of Trypace Tablet , take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take the next scheduled dose in the prescribed time. Do not double the dose to make up for the missed one as this may increase the risk of side effects.
No, taking a higher than the recommended dose may not be more effective, rather it may increase the risk of toxicity and serious side effects. If your symptoms are not relieved or there is an increased severity of your symptoms after using the recommended doses, please consult your doctor.
Trypace Tablet is contraindicated in patients with known allergy to any of its ingredients. Patients with a history of stomach ulcers or active, recurrent stomach ulcer/bleeding should ideally avoid taking Trypace Tablet . Additionally, patients with a history of high blood pressure, heart failure, and kidney or liver disease, should also avoid taking Trypace Tablet .

Country of origin

India

Manufacturer/Marketer address

G-2,SOMASHIVAM-7, MANSAROUR, BHIWANDI MUMBAI-421305
Other Info - TRY0146

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