TRYBOSIDE D TABLET belongs to the class of medications called ‘analgesics’ used to treat pain associated with various conditions. It is used in the treatment of pain, swelling, and inflammation associated with chronic (long-term) conditions such as osteoarthritis (joint pain, especially in the knees, hip, hands, neck, and lower back) and rheumatoid arthritis (joint pain, especially in the hands and feet). It can also relieve acute (short-term) pain such as toothache, ear pain, throat pain, muscle ache, and backache.

TRYBOSIDE D TABLET is a combination medicine that contains Trypsin, Bromelains, Rutoside, and Diclofenac. Trypsin and Bromelain are enzymes and have antiseptic and anti-inflammatory properties. They reduce pain, swelling, and inflammation by increasing the blood supply to the affected area. It can also promote healing. Rutoside is an antioxidant and anti-inflammatory agent. It prevents further swelling and inflammation by neutralizing the chemicals (free radicals) that cause cell damage. Diclofenac is a non-steroidal anti-inflammatory agent (NSAID) that prevents the production of chemical substances (prostaglandins) that cause pain and inflammation.

TRYBOSIDE D TABLET is available in the form of a tablet. You should take this medication exactly as prescribed by your doctor. TRYBOSIDE D TABLET may cause side effects such as nausea, vomiting, stomach pain, indigestion, heartburn, stomach upset, diarrhoea, headache, flushing (skin reddening), and skin rash. These side effects are usually mild and temporary. However, if any of these side effects persist or worsen, consult a doctor immediately.

Do not take TRYBOSIDE D TABLET if you are allergic to NSAIDs or any other contents of it. TRYBOSIDE D TABLET should not be used in patients with a history of stomach ulcers, active stomach ulcers or bleeding, or stomach problems due to NSAIDs, heart, liver, kidney disease, and poor blood circulation. TRYBOSIDE D TABLET should be used with caution in patients with ulcerative colitis (inflammation of the large intestine), other bowel disorders, porphyria (an inherited blood disorder), bleeding disorders, asthma, other respiratory infections, hypertension (high blood pressure), history of blood clots, high cholesterol, diabetes, history of smoking, and systemic lupus erythematosus (a skin disease). TRYBOSIDE D TABLET should also be used with caution in pregnant and breastfeeding women. TRYBOSIDE D TABLET is not recommended for children below 12 years of age. TRYBOSIDE D TABLET may require dose adjustments when used in elderly people. Alcohol may increase the risk of liver damage and side effects, such as nausea, vomiting, and diarrhoea. TRYBOSIDE D TABLET may cause dizziness, so do not drive or operate heavy machinery if you are dizzy.

TRYBOSIDE D TABLET contains Trypsin, Bromelains, Rutoside, and Diclofenac. Trypsin and Bromelain are enzymes and have antiseptic and anti-inflammatory properties. They reduce pain, swelling, and inflammation by increasing the blood supply to the affected area. It can also promote healing. Rutoside is an antioxidant and anti-inflammatory agent. It prevents further swelling and inflammation by neutralizing the chemicals (free radicals) that cause cell damage. Diclofenac is a non-steroidal anti-inflammatory agent (NSAID) that prevents the production of chemical substances (prostaglandins) that cause pain and inflammation. TRYBOSIDE D TABLET can be used to treat osteoarthritis, rheumatoid arthritis, toothache, ear pain, throat pain, and muscle pain. It can provide quick relief from the pain and promote faster healing of the affected tissue. It helps you to do your daily activities by decreasing the interference of pain and improving quality-of-life.

• Nausea
• Vomiting
• Stomach pain
• Indigestion
• Heartburn
• Stomach upset
• Diarrhoea
• Headache
• Flushing (skin reddening)
• Skin rash

TRYBOSIDE D TABLET should be used with caution in patients with heart diseases as it may increase heart rate. TRYBOSIDE D TABLET may cause liver damage, so regular monitoring of liver function is required if this medicine is taken for longer durations. If you are scheduled for surgery of the stomach or intestine, inform your doctor that you are taking TRYBOSIDE D TABLET as this medicine may delay wound healing. Do not overdose on medicine, as TRYBOSIDE D TABLET in higher doses may increase heart attack or stroke risk. 

Drug-Drug Interactions: TRYBOSIDE D TABLET may interact with other pain killers (aspirin and ibuprofen etc.), antibiotics (amoxicillin), medicines used to treat diabetes, blood thinner (warfarin), water pills, an antidepressant (lithium), other antidepressants, anticancer agent (methotrexate), drugs that suppress the immune system (ciclosporin and tacrolimus), a medicine used to treat urinary tract infections (trimethoprim), abortion drug (mifepristone), a medicine used to heart problems (digoxin), oral steroids, medicines used to treat high blood pressure, a medicine used to treat fits (phenytoin), antifungal agent (voriconazole), and medicines used to reduce cholesterol levels (colestipol and cholestyramine).

Drug-Food Interactions: No interactions found.

Drug-Disease Interactions: TRYBOSIDE D TABLET should not be used in patients with a history of stomach ulcers, active stomach ulcers or bleeding, or stomach problems due to NSAIDs, heart, liver, kidney disease, and poor blood circulation. TRYBOSIDE D TABLET should be used with caution in patients with ulcerative colitis (inflammation of the large intestine), other bowel disorders, porphyria ( an inherited blood disorder), bleeding disorders, asthma, other respiratory infections, hypertension (high blood pressure), history of blood clots, high cholesterol, diabetes, and systemic lupus erythematosus (a skin disease).

• ASPIRIN
• IBUPROFEN
• AMOXICILLIN
• WARFARIN
• LITHIUM
• METHOTREXATE
• CICLOSPORIN
• TACROLIMUS
• TRIMETHOPRIM
• MIFEPRISTONE
• DIGOXIN
• PHENYTOIN
• VORICONAZOLE
• COLESTIPOL
• CHOLESTYRAMINE

• Do not go for heavy exercise as it may increase your joint pain in arthritis. Instead, you can do stretching, low impact aerobic exercises like walking on the treadmill, bike riding, and swimming. You can also strengthen your muscles by lifting light weights.
• In the chronic conditions of arthritis or joint pain, try to include fish like salmon, trout, tuna, and sardines. These fishes are enriched with omega-3 fatty acids that minimize levels of chemicals called cytokines, which ramp up inflammation.
• Your sitting posture is important, especially when you have pain and inflammation. Try to sit as little as possible, and only for a short duration of time. Long-term immobility is harmful in conditions like arthritis.  Use back support like a rolled-up towel at the back of your spine curve to minimize pain. Keep your knees and hips at a right angle. Besides this, you can also use a footrest if required.

TRYBOSIDE D TABLET may increase the heart rate. Inform your doctor about any such symptoms.

Long-term use of TRYBOSIDE D TABLET may cause liver damage, your doctor may advise liver function for regular monitoring of liver function.

Pain: Pain is a symptom triggered by the nervous system, causing uncomfortable sensations in the body. It can be temporary (acute) or lifelong (chronic). Acute pain is, for a short time, caused by damage to the tissues of the muscle, bone, or organs. While chronic pain lasts lifelong and can occur due to severe inflammation or tissue damage, such as in cases of osteoarthritis and rheumatoid arthritis. Extreme tissue pain and inflammation caused due to sprains, strains, trauma, or post-surgery may require a prolonged amount of time to heal.

Osteoarthritis: It is a joint disease in which the two ends of the joints come together due to the breakdown of a protective covering of cartilage. Due to the absence of this protective covering, the joints rub against each other, leading to pain and stiffness. Symptoms include pain, stiffness, inflammation, and tenderness.

Rheumatoid arthritis: It is an auto-immune disease (the body's immune system attacks its tissue), leading to joint pain and damage. Symptoms of rheumatoid arthritis include pain, swelling, stiffness, deformities, and loss of joint function.