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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
Last Updated Oct 22, 2024 | 7:35 PM IST
Trulicity 1.5 mg Pre-Filled Pen 2 x 0.5 ml is an anti-diabetic medicine used in the treatment of Type II diabetes. This medicine increases insulin release from the pancreas during high blood sugar levels (after meals) and decreases the amount of sugar the liver makes, thus helping control blood sugar levels. This medicine may cause common side effects like nausea, vomiting, diarrhoea, decreased appetite, stomach pain, constipation, and feeling tired.
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Consume Type

PARENTERAL

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Not Returnable

Expires on or after

Jan-27

for this medicine

About Trulicity 1.5 mg Pre-Filled Pen 2 x 0.5 ml

Trulicity 1.5 mg Pre-Filled Pen 2 x 0.5 ml belongs to the class of anti-diabetic drugs primarily used to treat type 2 diabetes mellitus. Diabetes mellitus is a metabolic disease that causes high blood sugar levels. It occurs when the insulin (a hormone produced by the beta cells of the pancreas) is resistant in breaking the glucose to produce energy (insulin resistance) or the pancreas produces little or no insulin at all.

Trulicity 1.5 mg Pre-Filled Pen 2 x 0.5 ml contains Dulaglutide that belongs to the class of ‘incretin mimetics’. Dulaglutide works by increasing insulin release from the pancreas during high blood sugar levels (after meals) and decreasing the amount of sugar the liver makes. Trulicity 1.5 mg Pre-Filled Pen 2 x 0.5 ml also prevents the risk of heart diseases in type 2 diabetes patients.

Your doctor will decide the dose and duration of Trulicity 1.5 mg Pre-Filled Pen 2 x 0.5 ml based on your medical condition. Some common side effects of Trulicity 1.5 mg Pre-Filled Pen 2 x 0.5 ml include nausea, vomiting, diarrhoea, decreased appetite, stomach pain, constipation, and feeling tired. These side effects are not familiar to everyone and vary individually. If you notice any side effects that are not manageable, please consult your doctor.

Before starting Trulicity 1.5 mg Pre-Filled Pen 2 x 0.5 ml, let your doctor know if you have any medical history of heart, kidney or liver diseases. It is advised to limit your alcohol intake while using Trulicity 1.5 mg Pre-Filled Pen 2 x 0.5 ml to avoid low blood sugar levels. Pregnant and breastfeeding women should consult their doctor before starting Trulicity 1.5 mg Pre-Filled Pen 2 x 0.5 ml. Trulicity 1.5 mg Pre-Filled Pen 2 x 0.5 ml may make you feel tired, hence drive and operate machinery only when you are feeling better. Trulicity 1.5 mg Pre-Filled Pen 2 x 0.5 ml is not recommended for children and adolescents under 18 years of age.

Uses of Trulicity 1.5 mg Pre-Filled Pen 2 x 0.5 ml

Treatment of Type 2 Diabetes mellitus

Medicinal Benefits

Trulicity 1.5 mg Pre-Filled Pen 2 x 0.5 ml is used to treat type 2 diabetes mellitus. It is an incretin mimetic that mimics the action of a natural hormone called Incretin (a metabolic hormone that stimulates a decrease in blood glucose levels). It works by increasing insulin release from the pancreas during high blood sugar levels (after meals) and decreases the amount of sugar the liver makes. Trulicity 1.5 mg Pre-Filled Pen 2 x 0.5 ml also reduces the risk of serious heart diseases, such as heart attack or stroke in patients with type 2 diabetes and heart disease. Trulicity 1.5 mg Pre-Filled Pen 2 x 0.5 ml may be advised with or without other medications along with diet and exercise to control blood sugar levels. 

Directions for Use

Trulicity 1.5 mg Pre-Filled Pen 2 x 0.5 ml should be administered subcutaneously (under the skin) in the abdomen, thigh or upper arm. Your doctor or nurse will guide you on how to use the injection. Your doctor will prescribe the dosage based on your disease condition and tolerance. Your doctor may start the course with a low dose and gradually maintain an effective dose to achieve the required blood glucose control.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Trulicity 1.5 mg Pre-Filled Pen 2 x 0.5 ml

  • Nausea
  • Vomiting
  • Diarrhoea
  • Decreased appetite
  • Stomach pain
  • Constipation
  • Feeling tired

Drug Warnings

Brief your medical history to the doctor if you have heart, kidney or liver diseases, pancreatitis (inflammation of the pancreas), stomach disorders like acid reflux, gastroparesis (delayed gastric emptying), hypoglycaemia (low blood sugar levels), diabetic retinopathy, and type 1 diabetes before starting Trulicity 1.5 mg Pre-Filled Pen 2 x 0.5 ml. Trulicity 1.5 mg Pre-Filled Pen 2 x 0.5 ml is contraindicated in patients with multiple endocrine neoplasia type 2, diabetic ketoacidosis (diabetes complication where the body produces excess blood acids (ketones)), and personal or family history of thyroid cancer. Do not share an injection pen, cartridge, or syringe with another person, even if the needle is changed. It is advised to limit your alcohol intake while using Trulicity 1.5 mg Pre-Filled Pen 2 x 0.5 ml to avoid low blood sugar levels. Pregnant and breastfeeding women should consult their doctor before starting this medication. Trulicity 1.5 mg Pre-Filled Pen 2 x 0.5 ml may make you feel tired; hence drive and operate machinery only when you are feeling better. Trulicity 1.5 mg Pre-Filled Pen 2 x 0.5 ml is not recommended for children and adolescents under 18 years of age.

Drug Interactions

Drug-Drug Interaction: Trulicity 1.5 mg Pre-Filled Pen 2 x 0.5 ml may interact with other anti-diabetic medicines (insulin glargine), hormones (levothyroxine), high blood pressure medicines (propranolol, metoprolol), and glaucoma eye drops (timolol). 

Drug-Food Interaction: Limit alcohol intake since it affects blood sugar levels. Avoid fatty foods and include healthy carbohydrates in your diet.

Drug-Disease Interaction: Tell your doctor before taking Trulicity 1.5 mg Pre-Filled Pen 2 x 0.5 ml if you have a medical history of allergic reactions to medicines, heart, kidney or liver diseases, pancreatitis, gastroparesis, reflux, and hypoglycaemia. Trulicity 1.5 mg Pre-Filled Pen 2 x 0.5 ml is contraindicated in patients with multiple endocrine neoplasia type 2, diabetic ketoacidosis, and personal or family history of thyroid cancer.

Drug-Drug Interactions Checker List

  • INSULIN GLARGINE
  • LEVOTHYROXINE
  • PROPRANOLOL
  • METOPROLOL
  • TIMOLOL

Habit Forming

No

Diet & Lifestyle Advise

  • Maintain a fibre-rich diet and include healthy carbohydrates from fruits, vegetables and whole grains to maintain your blood glucose levels.
  • Eat at regular intervals.
  • Keep a check on your weight and exercise regularly to keep your heart healthy.
  • Follow your doctor's guide on noticing and managing the early symptoms of high/low blood sugar levels.
  • Gastrointestinal side effects can be managed with simple modifications in your lifestyle. These include cutting down on sugars and fatty foods, avoiding carbonated drinks and foods that cause gas. 

Special Advise

It is advised to monitor your blood sugar levels regularly.

Disease/Condition Glossary

Diabetes mellitus: It is a metabolic disease that causes high blood sugar levels. Diabetes mellitus is also known as adult-onset diabetes. It occurs when the insulin (a hormone produced by the beta cells of the pancreas) is resistant in breaking the glucose to produce energy (insulin resistance) or the pancreas (an organ behind the stomach) produce little or no insulin at all. This disease mostly occurs in people above 40 years but can also occur in childhood based on the risk factors. The treatment includes oral glucose-lowering medicines and insulin shots. 

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Alcohol

Caution

It is advised to limit alcohol intake since it may worsen the side effects and increase the risk of developing low blood sugar levels.

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Pregnancy

Caution

Please consult your doctor before starting Trulicity 1.5 mg Pre-Filled Pen 2 x 0.5 ml if you are pregnant or planning to conceive. Your doctor will prescribe only if the benefit outweighs the risk.

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Breast Feeding

Caution

There is no sufficient data on how Trulicity 1.5 mg Pre-Filled Pen 2 x 0.5 ml affects breastfeeding. It is safe to seek medical advice before starting Trulicity 1.5 mg Pre-Filled Pen 2 x 0.5 ml if you are lactating.

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Driving

Caution

Do not drive or operate machinery if you experience any signs of low blood sugar.

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Liver

Caution

Let your doctor know if you have any history of liver diseases or hepatic impairment when prescribed Trulicity 1.5 mg Pre-Filled Pen 2 x 0.5 ml.

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Kidney

Caution

Let your doctor know if you have any history of kidney diseases when you are prescribed Trulicity 1.5 mg Pre-Filled Pen 2 x 0.5 ml.

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Children

Unsafe

Trulicity 1.5 mg Pre-Filled Pen 2 x 0.5 ml is not recommended for children and adolescents under 18 years of age.

Country of origin

INDIA

Manufacturer/Marketer address

Plot# 92, Sector 32, Institutional Area, Gurgaon-122001, HARYANA, INDIA
Other Info - TRU0444

Author Details

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FAQs

Trulicity 1.5 mg Pre-Filled Pen 2 x 0.5 ml belongs to the class of anti-diabetic drugs primarily used to treat type 2 diabetes mellitus.
Trulicity 1.5 mg Pre-Filled Pen 2 x 0.5 ml contains Dulaglutide that increases the insulin release from the pancreas after meals when your body has high blood glucose levels. Thus, Trulicity 1.5 mg Pre-Filled Pen 2 x 0.5 ml helps lower the blood sugar levels in type 2 diabetes mellitus.
Trulicity 1.5 mg Pre-Filled Pen 2 x 0.5 ml may cause low blood sugar levels (hypoglycaemia) and can make you hungry, dizzy, irritable, confused, anxious, or shaky. Hence, it is advised to take Trulicity 1.5 mg Pre-Filled Pen 2 x 0.5 ml with a meal. To immediately treat hypoglycaemia, it is advised to eat or drink fast-acting sugar sources like fruit juices, hard candy, raisins, or non-diet soda.
Use injection solution only if it is clear, colourless, and contains no particles. Administer the injection subcutaneously (under the skin) in the abdomen, thigh or upper arm. Your doctor or nurse will guide you on how to use the injection. You can take Trulicity 1.5 mg Pre-Filled Pen 2 x 0.5 ml with or without a meal. However, it is advised to take the injection preferably with a meal since it lowers the blood sugar levels and may cause gastrointestinal side effects. Do not share an injection pen, cartridge, or syringe with another person, even if the needle is changed.
Your doctor may advise Trulicity 1.5 mg Pre-Filled Pen 2 x 0.5 ml with or without other medications to control your blood sugar levels. Take Trulicity 1.5 mg Pre-Filled Pen 2 x 0.5 ml with other anti-diabetic medicines only if prescribed by the doctor. If you are also prescribed insulin, take Trulicity 1.5 mg Pre-Filled Pen 2 x 0.5 ml and insulin injections separately. Please do not mix them. You can inject both injections in the same body region, but the injection sites should not be next to each other.
Take the missed dose as soon as possible. However, if it is time for the next dose, skip the missed dose and return to your regular dosing schedule. Do not double the dose.
Store the unused Trulicity 1.5 mg Pre-Filled Pen 2 x 0.5 ml in a refrigerator at 2°C to 8°C protected from the light. You may also store Trulicity 1.5 mg Pre-Filled Pen 2 x 0.5 ml at room temperature of 15°C to 30°C for up to 14 days before use. Do not freeze Trulicity 1.5 mg Pre-Filled Pen 2 x 0.5 ml. Do not use Trulicity 1.5 mg Pre-Filled Pen 2 x 0.5 ml if it is frozen.
Cut back on foods high in sodium, alcohol, fried foods, and high-carb food and drinks like sugary drinks, drinks with added sugar, white rice and starchy vegetables.
Trulicity 1.5 mg Pre-Filled Pen 2 x 0.5 ml should not be discontinued without a doctor's consultation. Consult the doctor if you feel uncomfortable after taking Trulicity 1.5 mg Pre-Filled Pen 2 x 0.5 ml.
The injection site should be changed to prevent skin changes like lumps under the skin. Trulicity 1.5 mg Pre-Filled Pen 2 x 0.5 ml may not work well if injected into the lumpy area.
Maintain a healthy diet and exercise regularly. Limit sugar intake and avoid smoking & alcohol consumption. Manage stress by doing meditation or yoga.
Hypoglycaemia (low blood sugar) may occur because you inject too much insulin, miss or delay meals, do not eat enough, eat food containing less carbohydrate than normal, drink alcohol, lose carbohydrates due to vomiting or diarrhoea, do more exercise than usual or a different type of physical activity, are recovering from an injury, illness, operation or stress, or are taking/have stopped taking other medicines.
A haemoglobin A1C (HbA1C) test is used to diagnose type 2 diabetes and prediabetes. It helps measure the amount of blood glucose attached to haemoglobin. It is used to monitor your condition and check how well you've been able to control your blood sugar levels.
Trulicity 1.5 mg Pre-Filled Pen 2 x 0.5 ml can be taken at any time of the day, with or without meals.
Trulicity 1.5 mg Pre-Filled Pen 2 x 0.5 ml slows down digestion, which causes the person to eat less, leading to weight loss. However, Trulicity 1.5 mg Pre-Filled Pen 2 x 0.5 ml is not indicated for weight loss.
No, Trulicity 1.5 mg Pre-Filled Pen 2 x 0.5 ml is not an insulin. It contains Dulaglutide, an anti-diabetic drug.
Trulicity 1.5 mg Pre-Filled Pen 2 x 0.5 ml can be taken with insulin if prescribed by the doctor. Please do not mix them, take Trulicity 1.5 mg Pre-Filled Pen 2 x 0.5 ml and insulin separately. You may give an injection of Trulicity 1.5 mg Pre-Filled Pen 2 x 0.5 ml and insulin in the same body area (such as the stomach area), but not right next to each other.
No, Trulicity 1.5 mg Pre-Filled Pen 2 x 0.5 ml is not used to treat type 1 diabetes. It is used to treat type 2 diabetes mellitus.
Trulicity 1.5 mg Pre-Filled Pen 2 x 0.5 ml may cause pancreatitis (inflammation of the pancreas). Stop using Trulicity 1.5 mg Pre-Filled Pen 2 x 0.5 ml and consult the doctor if you have severe pain in your stomach area (abdomen) that will not go away, with or without vomiting.
Regular self-monitoring of blood sugar may not be required while taking Trulicity 1.5 mg Pre-Filled Pen 2 x 0.5 ml. However, regular self-monitoring of blood sugar may be required while taking Trulicity 1.5 mg Pre-Filled Pen 2 x 0.5 ml with other anti-diabetic medicines.
Avoid foods high in sugar and fried or fatty food. Also, do not eat saturated, trans-fat, and greasy foods.
Trulicity 1.5 mg Pre-Filled Pen 2 x 0.5 ml may cause serious side effects like possible thyroid tumours, including cancer. Inform your doctor if you notice symptoms of thyroid cancer such as a lump or swelling in your neck, hoarseness, trouble swallowing, or shortness of breath.
Yes, Trulicity 1.5 mg Pre-Filled Pen 2 x 0.5 ml can be used with other diabetes medicines if prescribed by the doctor.
Yes, you can take a protein-rich diet along with Trulicity 1.5 mg Pre-Filled Pen 2 x 0.5 ml. Proteins which are building blocks of the body are one of the major energy providers. They break down into glucose to release energy.
Though artificial sweeteners may not affect blood sugar levels, it is advised to consult a doctor before using artificial sweeteners while taking Trulicity 1.5 mg Pre-Filled Pen 2 x 0.5 ml.
Uncontrolled diabetes may cause kidney problems leading to diabetic nephropathy. To prevent this, keep your blood sugar levels under control and regularly monitor your kidney function.
No, there is no cure for diabetes. However, using diabetic medicines and following diet and exercise may help manage diabetes.

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