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Written By ,
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 9, 2024 | 12:36 PM IST
Trofentyl OTFC Tablet is used to treat pain. It contains Fentanyl, which works by blocking a chemical messenger in the brain responsible for causing pain. Hence, it changes how the brain and nervous system respond to pain. Common side effects of Trofentyl OTFC Tablet are dizziness, sleepiness, increased or decreased blood pressure, and irregular heartbeat. This medicine is not recommended for children below 18 years of age.
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Prescription drug

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Synonym

FENTANYL CITRATE

Composition

FENTANYL-200MCG

Manufacturer/Marketer

Troikaa Pharmaceuticals Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Trofentyl OTFC Tablet

Trofentyl OTFC Tablet belongs to a class of medicines known as 'opioid analgesics,' primarily used to relieve pain. It is used to treat breakthrough pain (sudden episodes of pain occurring despite treatment with pain medication) in cancer patients. Pain can be temporary (acute) or long-lasting (chronic) in nature. Acute pain is caused by damage to the tissues of the muscle, bone, or other organs for a short time. Chronic pain lasts for a long duration and is caused due to pathologies like nerve damage and osteoarthritis.

Trofentyl OTFC Tablet contains Fentanyl. It works by blocking a chemical messenger in the brain responsible for causing pain. Hence, changing the way the brain and nervous system respond to pain.

Trofentyl OTFC Tablet should be used as recommended. Trofentyl OTFC Tablet may cause certain side effects such as dizziness, sleepiness, increased or decreased blood pressure, and irregular heartbeat in some cases. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently. 

Trofentyl OTFC Tablet should be avoided if you are allergic to opioids or any ingredients of Trofentyl OTFC Tablet.  Inform your doctor before taking Trofentyl OTFC Tablet if you have respiratory disorders, heart diseases, high blood pressure, and liver or kidney disease. Avoid consuming alcohol along with Trofentyl OTFC Tablet as it could lead to increased dizziness. Do not take Trofentyl OTFC Tablet for a prolonged time as it may lead to mental or physical dependence on Trofentyl OTFC Tablet. This medicine is not recommended for children below 18 years of age. Do not use this medicine if you have used an MAO inhibitor in the past 14 days, as it this combination may cause serious interaction. Blood pressure and cardiovascular (heart) status should be monitored closely during the treatment with Trofentyl OTFC Tablet, especially in people affected with high blood pressure and a history of heart failure.

Uses of Trofentyl OTFC Tablet

Treatment of Pain

Medicinal Benefits

Trofentyl OTFC Tablet belongs to a class of drugs known as 'opioid analgesics,' containing Fentanyl, primarily used to relieve pain. It is used to treat breakthrough pain (sudden episodes of pain occurring despite treatment with pain medication) in cancer patients. It is also used as an anaesthetic agent for short operations and relieves pain in conditions like rheumatoid arthritis and osteoarthritis and pain affecting the joints and muscles. It works by blocking a chemical messenger in the brain responsible for causing pain. Hence, changing the way the brain and nervous system respond to pain.

Directions for Use

Lozenge: Take Trofentyl OTFC Tablet as advised by your physician. Do not take more than the prescribed dose of medicine. Do not chew or break the medicine.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Trofentyl OTFC Tablet

  • Nausea and vomiting
  • Muscle stiffness
  • Agitation
  • Drowsiness
  • Dizziness
  • Problems with vision
  • Difficulty in breathing or wheezing
  • Choking is caused by cramping (spasm) of the muscles in your throat
  • Low or high blood pressure
  • Irregular heartbeat (slow or fast)
  • Pain in your veins
  • Difficulty with body movements
  • Skin rash
  • Confusion after the operation

Drug Warnings

Do not take Trofentyl OTFC Tablet if you are allergic to opioids or any ingredients of Trofentyl OTFC Tablet. Inform your doctor if you have respiratory disorders, heart diseases, high blood pressure, and liver or kidney disease or hypothyroidism (underactive thyroid). Do not take Trofentyl OTFC Tablet for a prolonged time, Trofentyl OTFC Tablet contains fentanyl that may lead to mental or physical dependence on Trofentyl OTFC Tablet. Do not take Trofentyl OTFC Tablet if you are pregnant or breastfeeding, as it may cause adverse effects on the baby. Trofentyl OTFC Tablet is not recommended for children below 18 years of age. Do not use this medicine if you have used an MAO inhibitor in the past 14 days, as a dangerous drug interaction could occur. Trofentyl OTFC Tablet should be taken with extreme caution in patients who have a history of alcoholism or drug abuse. Avoid consuming alcohol while on this medication, as it can lead to excessive sleepiness. Blood pressure and cardiovascular (heart) status should be monitored closely during the treatment with Trofentyl OTFC Tablet, especially in people affected with high blood pressure and a history of heart failure.

Drug Interactions

Drug-Drug Interactions: Trofentyl OTFC Tablet is known to interact with antihistamines (cetirizine, phenylephrine), anti-HIV medicines (ritonavir, indinavir, saquinavir), anti-anxiety medicines (droperidol),  anti-fungal medicines (fluconazole, voriconazole), anti-depressants (citalopram, duloxetine, escitalopram, fluoxetine, fluvoxamine, paroxetine, sertraline, venlafaxine).

Drug-Food Interactions: Trofentyl OTFC Tablet is known to interact with alcohol and grapefruit juice.

Drug-Disease Interactions: Trofentyl OTFC Tablet is known to interact in patients who have or had an underactive thyroid gland, lung disease, myasthenia gravis (a muscle disorder), liver or kidney disease, alcoholism, severe undiagnosed headaches, or recently suffered a head injury, low blood volume, pain in the right upper side of your abdomen (bile duct).

Drug-Drug Interactions Checker List

  • CETIRIZINE
  • PHENYLEPHRINE
  • RITONAVIR
  • PAROXETINE
  • FLUCONAZOLE
  • VORICONAZOLE
  • ESCITALOPRAM
  • CITALOPRAM

Habit Forming

No

Diet & Lifestyle Advise

  • Do not go for heavy exercise as it may increase your joint pain in arthritis. Instead, you can do stretching and low-impact aerobic exercises like walking on a treadmill, bike riding, and swimming. You can also strengthen your muscles by lifting light weights.
  • In the chronic condition of arthritis or joint pain, including fish like salmon, trout, tuna, and sardines. These fishes are enriched with omega-3 fatty acids that have a minimum level of chemicals called cytokines, which ramp up inflammation.
  • Your sitting posture is important, especially when you have pain and inflammation. Try to sit as little as possible, and only for a short duration of time. Long-term immobility is harmful in conditions like arthritis.  Use back support like a rolled-up towel to minimise pain at the back of your spine curve. Keep your knees and hips at a right angle. Besides this, you can also use a footrest if required.
  • Include a diet rich in whole grains, vegetables, and fruits. This is a healthier option than eating many simple carbohydrates in processed foods.

Special Advise

  • Regular monitoring of blood pressure and heart rate is required while taking Trofentyl OTFC Tablet.
  • Trofentyl OTFC Tablet causes drowsiness. Avoid doing activities that require complete focus and attention.
  • An abrupt stoppage of Trofentyl OTFC Tablet can lead to significant withdrawal symptoms. Always discuss with your doctor about decreasing the dosage before completely stopping its usage.
  • Avoid consuming alcohol while on this medication, as it can lead to dangerous side effects.
  • Trofentyl OTFC Tablet is unsafe for usage if you're pregnant or are planning to get pregnant. Discuss with your doctor in such situations about changing/replacing the medicine with safer alternatives.
  • To avoid getting addicted to this drug, take it in prescribed quantities and as directed by your doctor. Do not self-medicate.
  • Trofentyl OTFC Tablet should not be administered during labour as it may affect the baby’s breathing.

Disease/Condition Glossary

Pain: It can be short-term (acute) or long-term (chronic) in nature. Acute pain is, for a short time, caused by damage to the tissues of the muscle, bone, or organs. Chronic pain lasts for a longer duration and is caused due to pathologies like nerve damage, osteoarthritis, and dental pain due to damage to the tooth nerve, infection, decay, extraction, or injury. Many women have painful periods known as dysmenorrhea, most often menstrual cramps. On the other hand, Osteoarthritis is a degenerative disease that results in chronic pain in joints (especially knee) and stiffness, making daily tasks difficult.

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Alcohol

Unsafe

Consumption of alcohol while using Trofentyl OTFC Tablet may worsen dizziness or drowsiness. Besides this, it can also damage your liver if taken for a longer duration. So, avoid or limit intake of alcoholic beverages while on treatment with Trofentyl OTFC Tablet.

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Pregnancy

Unsafe

Trofentyl OTFC Tablet is a pregnancy category C drug. It is not recommended for use in pregnancy as it may harm your foetus. Hence, if you are pregnant or planning pregnancy, inform your doctor before taking Trofentyl OTFC Tablet. Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Breast Feeding

Unsafe

It may be unsafe to use during breastfeeding as it may cause sleepiness and decreased heart rate in the breastfeeding child. Hence, if you are a breastfeeding mother, inform your doctor before taking Trofentyl OTFC Tablet. Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Driving

Unsafe

Trofentyl OTFC Tablet is known to cause dizziness, sleepiness, and drowsiness. So, do not drive or operate any machinery.

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Liver

Caution

Trofentyl OTFC Tablet to be taken with caution, especially if you have a history of liver disease. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Kidney

Caution

Trofentyl OTFC Tablet to be taken with caution, especially if you have a history of kidney disease Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Children

Unsafe

Trofentyl OTFC Tablet is not recommended for children below the age of 18 years.

Country of origin

India

Manufacturer/Marketer address

Troikaa Pharmaceuticals Ltd., Registered Office: , 'Commerce House - 1', Satya Marg, Bodakdev, Ahmedabad-380 054. Gujarat, India.
Other Info - TRO0329

FAQs

Trofentyl OTFC Tablet is used to treat pain.
Trofentyl OTFC Tablet contains Fentanyl which works by blocking a chemical messenger in the brain responsible for causing pain. Hence, changing the way the brain and nervous system respond to pain.
Yes, Trofentyl OTFC Tablet sometimes may make you breathe more slowly than usual or can cause shortness of breath. If you feel so, please inform your doctor immediately. Also, people with any breathing problems should inform their doctor before starting Trofentyl OTFC Tablet.
Elderly patients (aged more than 65 years) are more likely to have confusion and sleepiness or age-related health issues, which may require caution and an adjustment in the dose for patients taking Trofentyl OTFC Tablet. So, it is better to consult a doctor before taking this medicine.
Trofentyl OTFC Tablet is a habit-forming drug. It is not likely to be addictive if you take it for 2-4 weeks. However, if the doctor has prescribed you for more than 2-4 weeks, your doctor may reduce your dose before completely stopping it.
Do not stop taking Trofentyl OTFC Tablet until instructed by your doctor. You may get side effects like confusion, depression, nervousness, sweating, and diarrhoea. Your doctor may lower the dose of Trofentyl OTFC Tablet if using it for more than 2-4 weeks of treatment to reduce side effects.

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