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Written By Veda Maddala , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Last Updated Oct 30, 2024 | 5:55 AM IST

Trizonia-5 Tablet is used to treat schizophrenia. It may also be used to treat anxiety and depression. It contains Trifluoperazine which works by inhibiting the chemical messenger (dopamine) that regulates mood, behaviour, and emotions. In some cases, this medicine may cause side effects such as restlessness, weakness, drowsiness, dizziness, dry mouth, loss of appetite, and blurred vision. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Prescription drug

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Synonym

TRIFLUOPERAZINE HYDROCHLORIDE

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Trizonia-5 Tablet

Trizonia-5 Tablet belongs to a class of drugs called 'antipsychotics' used to prevent and treat relapses of schizophrenia (a mental illness). Additionally, Trizonia-5 Tablet may be used for anxiety and depression over a short period, nausea and vomiting. Schizophrenia is a mental disorder that affects a person's ability to feel, think and behave clearly. Anxiety is a mental health disorder associated with fear, worry, and excessive nervousness that may interfere with daily activities. Depression is a mood disorder associated with symptoms such as sadness, and unable to sleep properly or enjoy life as you used to do.

Trizonia-5 Tablet contains Trifluoperazine, which works by inhibiting the dopamine (chemical messenger) receptors in the brain. Dopamine is involved in regulating mood, behaviour, and emotions. Thereby, Trizonia-5 Tablet helps control psychotic illness, relieve depression, lighten the mood and relieve anxiety symptoms such as fear and panic. Also, Trizonia-5 Tablet blocks dopamine receptors in the chemoreceptor trigger zone (CTZ) and inhibits transmission of messages to the vomiting center. Thereby, it helps in controlling nausea and vomiting.

Take Trizonia-5 Tablet as prescribed by your doctor. You are advised to take Trizonia-5 Tablet for as long as your doctor has prescribed it for you based on your medical condition. Some people may experience restlessness, weakness, drowsiness, dizziness, dry mouth, loss of appetite, blurred vision or eye problems, muscle weakness, fainting on standing up, confusion, weight gain, or water retention causing swelling. Most of these side effects of Trizonia-5 Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Trizonia-5 Tablet or any other medicines, please tell your doctor. The tablet form is not recommended for children below 6 years, and the syrup is not recommended for children below 3 years of age. Avoid taking Trizonia-5 Tablet if you are pregnant, especially in the third trimester, as it may cause adverse effects in the baby, such as breathing problems, muscle stiffness or weakness, shaking, etc. Please consult a doctor if you are pregnant or breastfeeding. Trizonia-5 Tablet should be used with caution in elderly patients above 65 years, as there is an increased risk of adverse reactions. Do not consume alcohol with Trizonia-5 Tablet as it may cause adverse effects such as severe dizziness or fainting, irregular heartbeats, drowsiness, uncontrollable movements, fits, drowsiness, and high or low body temperature. Avoid taking Trizonia-5 Tablet if you have blood disorders, liver problems, or the heart's inability to maintain adequate circulation.

Uses of Trizonia-5 Tablet

Trizonia-5 Tablet is used in the treatment of Schizophrenia, Anxiety, Depression, Nausea and Vomiting.

Medicinal Benefits

Trizonia-5 Tablet contains Trifluoperazine, an antipsychotic used to prevent and treat relapses of schizophrenia (a mental illness). Additionally, Trizonia-5 Tablet may be used for anxiety and depression over a short period, nausea and vomiting. Trizonia-5 Tablet inhibits the dopamine (chemical messenger) receptors in the brain. Dopamine is involved in regulating mood, behavior, and emotions. Thereby, Trizonia-5 Tablet helps in controlling psychotic illness, relieving depression, lightening the mood, and relieving anxiety symptoms such as fear and panic. Also, Trizonia-5 Tablet blocks dopamine receptors in the chemoreceptor trigger zone (CTZ) and inhibits transmission of messages to the vomiting center. Thereby, it helps in controlling nausea and vomiting.

Directions for Use

Tablet: Take it with or without food as prescribed by your doctor. Swallow it as a whole with a glass of water. Do not break, crush or chew it.Syrup: Shake the bottle well before use. Take the prescribed dose by mouth using the measuring cup/dosing syringe/dropper provided by the pack.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Trizonia-5 Tablet

  • Restlessness
  • Weakness
  • Drowsiness
  • Dizziness
  • Dry mouth
  • Loss of appetite
  • Blurred vision or eye problems
  • Muscle weakness
  • Fainting on standing up
  • Confusion
  • Weight gain
  • Water retention causes swelling

Drug Warnings

Please tell your doctor if you are allergic to Trizonia-5 Tablet or any other medicines, please tell your doctor. Avoid taking Trizonia-5 Tablet if you are pregnant, especially in the third trimester, as it may cause adverse effects in the baby, such as breathing problems, muscle stiffness or weakness, shaking, etc. Please consult a doctor if you are pregnant or breastfeeding. Trizonia-5 Tablet should be used with caution in elderly patients above 65 years, as there is an increased risk of adverse reactions. Avoid taking Trizonia-5 Tablet if you have blood disorders, liver problems or an inability of the heart to maintain adequate circulation. Do not consume alcohol with Trizonia-5 Tablet as it may cause adverse effects such as severe dizziness or fainting, irregular heartbeats, drowsiness, uncontrollable movements, fits, drowsiness, and high or low body temperature. If you have Parkinson’s disease, fits, narrow-angle glaucoma, myasthenia gravis (muscle weakness), enlarged prostate gland, dementia (decline in memory, intelligence or communication), uncontrolled high blood pressure, high cholesterol, diabetes, have a family history of stroke or blood clots, liver, heart or brain problems, inform your doctor before taking Trizonia-5 Tablet .

Drug Interactions

Drug-Drug Interaction: Trizonia-5 Tablet may have interaction with high blood pressure-lowering medicines (guanethidine), opioid pain killers (codeine), medicines used to decrease saliva and lung secretions (atropine, procyclidine), antipsychotics (promazine, prochlorperazine, chlorpromazine), anticonvulsants (lamotrigine, pregabalin), antiparkinson drug (levodopa), blood thinner (warfarin), a medicine used to treat iron poisoning (desferrioxamine), heart-related medicines (disopyramide, procainamide, quinidine, amiodarone, sotalol).

Drug-Food Interaction: Trizonia-5 Tablet may interact with alcohol. Therefore, avoid alcohol intake while taking Trizonia-5 Tablet as it may cause adverse effects such as severe dizziness or fainting, irregular heartbeats, drowsiness, uncontrollable movements, fits, and high or low body temperature.

Drug-Disease Interaction: Avoid taking Trizonia-5 Tablet if you have blood disorders, liver problems, or the heart's inability to maintain adequate circulation. If you have Parkinson’s disease, fits, narrow-angle glaucoma, myasthenia gravis (muscle weakness), enlarged prostate gland, dementia (decline in memory, intelligence or communication), uncontrolled high blood pressure, high cholesterol, diabetes, have a family history of stroke or blood clots, liver, heart or brain problems, inform your doctor before taking Trizonia-5 Tablet .

Drug-Drug Interactions Checker List

  • GUANETHIDINE
  • CODEINE
  • PROCYCLIDINE
  • ATROPINE
  • PROCHLORPERAZINE
  • CHLORPROMAZINE
  • LAMOTRIGINE
  • PREGABALIN
  • LEVODOPA
  • WARFARIN
  • DISOPYRAMIDE
  • PROCAINAMIDE
  • QUINIDINE
  • AMIODARONE
  • SOTALOL
  • PROMAZINE
  • DESFERRIOXAMINE

Habit Forming

No

Diet & Lifestyle Advise

  • Exercise regularly and maintain a healthy body weight.
  • Maintain a diet rich in fruits, vegetables, and whole grains. Avoid fried foods, high-fat dairy products, pastries, and processed foods as they may worsen anxiety.
  • Follow a regular sleep pattern. Do not take a nap during day time.
  • Avoid watching tv, and using mobiles or laptops just before bedtime.
  • Avoid consumption of alcohol as it may increase drowsiness.

Special Advise

  • If you have a special X-ray examination of the spinal cord or brain involving metrizamide (chemical), inform your doctor that you are taking Trizonia-5 Tablet .
  • Blood tests are recommended while taking Trizonia-5 Tablet to monitor blood counts and liver function.
  • This medication may make you more sensitive to the sun. Limit your time in the sun, avoid tanning booths and sunlamps, use sunscreen, and wear protective clothing when outdoors. Tell your doctor right away if you get sunburned or have skin blisters or redness.
  • This medication may make you sweat less, making you more likely to get heat stroke. Avoid doing things that may cause you to overheat, such as hard work or exercise in hot weather, or using hot tubs. When the weather is hot, drink lots of fluids and dress lightly.

Disease/Condition Glossary

Schizophrenia: It is a mental disorder that affects a person's ability to feel, think and behave clearly. The symptoms include hallucinations, thought or movement disorders, delusions (misbelief), lack of emotion, sleep problems, isolation from family and friends, and difficulty in doing daily activities.

Anxiety: It is a mental health disorder associated with fear, worry, and excessive nervousness that may interfere with daily activities. The anxiety symptoms include feeling more stress than required for that event and a lack of ability to set aside restlessness and worry. Anxiety can be treated by psychotherapy (meeting a psychologist) or medications.

Depression: It is a mood disorder associated with symptoms such as sadness, unable to sleep properly, or enjoy life as you used to do.

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Alcohol

Unsafe

Avoid consumption of alcohol with Trizonia-5 Tablet as it may increase the risk of drowsiness and other adverse effects.

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Pregnancy

Unsafe

Trizonia-5 Tablet is not recommended for use during pregnancy, especially in the third trimesters as it may cause adverse effects in the baby. Please consult a doctor if you are pregnant or planning for pregnancy.

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Breast Feeding

Unsafe

Trizonia-5 Tablet may be unsafe to use during breastfeeding. Please consult a doctor if you are breastfeeding.

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Driving

Unsafe

Trizonia-5 Tablet may cause dizziness, double vision or drowsiness in some people. Therefore, avoid driving if you feel drowsy, dizzy or experience any vision problems after taking Trizonia-5 Tablet .

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Liver

Unsafe

Trizonia-5 Tablet is not recommended for patients suffering from Liver diseases/conditions. Please consult a doctor if you have any concerns regarding this.

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Kidney

Caution

Take Trizonia-5 Tablet with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Caution

Use Trizonia-5 Tablet in children in prescribed doses. Your doctor will determine the dose based on your child's condition, age, and body weight.

Country of origin

India

Manufacturer/Marketer address

ADMINISTRATION BLOCK, IVY HOSPITAL SECTOR-71, SAS NAGAR MOHALI Mohali PB 160071 IN
Other Info - TRI1637

Author Details

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FAQs

Trizonia-5 Tablet is used to treat schizophrenia (a mental illness). Additionally, it may be used for anxiety, depression, nausea and vomiting.
Trizonia-5 Tablet contains Trifluoperazine, an antipsychotic that works by inhibiting the dopamine (chemical messenger) receptors in the brain. Dopamine is involved in regulating mood, behaviour and emotions. Thereby, Trizonia-5 Tablet helps in relieving depression, lighten the mood and relieve anxiety symptoms such as fear and panic. Also, Trizonia-5 Tablet blocks dopamine receptors in the chemoreceptor trigger zone (CTZ) and inhibits transmission of messages to the vomiting centre. Thereby, it helps in controlling nausea and vomiting.
You are not recommended to take Trizonia-5 Tablet with levodopa (antiparkinson drug) as it may decrease the effectiveness of levodopa and increase the risk of adverse effects such as low blood pressure, drowsiness, light-headedness and dizziness. However, please consult your doctor before using Trizonia-5 Tablet with any other medicines.
Trizonia-5 Tablet should be avoided by dementia (decline in memory, behaviour, thinking and ability to do daily activities) patients as it may increase the risk of severe adverse effects. Therefore, inform your doctor if you are suffering from dementia before taking Trizonia-5 Tablet .
Trizonia-5 Tablet may be used to treat nausea and vomiting. Trizonia-5 Tablet blocks dopamine receptors in the chemoreceptor trigger zone (CTZ) in the brain and inhibits transmission of messages to vomiting centre. Thereby, it helps in controlling nausea and vomiting.
Trizonia-5 Tablet may cause dizziness, especially while standing up suddenly from a sitting or lying position. Therefore, to avoid such adverse effects, standing up slowly if you are sitting or lying down is advised. However, if the condition persists or worsens, please consult a doctor.
Trizonia-5 Tablet should be used cautiously in patients suffering from fits as it may worsen the condition. Therefore, inform your doctor if you have a history of fits before taking Trizonia-5 Tablet .
Trizonia-5 Tablet medication may cause face/muscle twitching and uncontrollable movements (tardive dyskinesia). In some cases, this condition may be permanent. Tell your doctor immediately if you develop any uncontrollable movements such as lip smacking, mouth puckering, tongue thrusting, chewing, or unusual arm/leg movements.

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