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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Last Updated Dec 7, 2024 | 2:25 PM IST
Trivastal LA Tablet is used in the treatment of Parkinson's disease. It contains Piribedil, which increases dopamine (chemical messenger important for movement control) levels in the brain. It can effectively treat symptoms of Parkinson's disease and improve the quality of life. It may cause common side effects such as nausea, vomiting, flatulence (gas), confusion, hallucinations, dizziness, and drowsiness.
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Composition

PIRIBEDIL-50MG

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Trivastal LA Tablet

Trivastal LA Tablet belongs to a group of medications called ‘antiparkinson agents. Parkinson’s disease is a central nervous system disorder affecting movement and locomotion. It causes stiffness, shaking, difficulty walking, coordination, and balance. These symptoms interfere with daily activities and decrease the quality of life.

Trivastal LA Tablet contains ‘Piribedil’, which is an antiparkinson agent. It is a dopamine agonist and acts by increasing the dopamine levels in the brain. Dopamine is a chemical messenger in the brain that is important for movement control. Trivastal LA Tablet can effectively treat symptoms of Parkinson’s disease and improve quality of life.

Take this medicine exactly as prescribed by your doctor. The common side effects of Trivastal LA Tablet are nausea, vomiting, flatulence, confusion, hallucinations, agitation, dizziness, and drowsiness. These side effects usually improve after discontinuation of therapy. However, if any of these side effects persist or worsen during or after the treatment, inform your doctor immediately.

Do not take Trivastal LA Tablet if you are allergic to Piribedil or any other ingredients present in it. Trivastal LA Tablet should not be used in patients with cardiovascular shock (a serious condition in which the heart suddenly stops pumping blood) and acute myocardial infarction (heart attack). There is no relevance to establishing the use of Trivastal LA Tablet in pregnant or breastfeeding women. Trivastal LA Tablet intended for use in elderly people. Alcohol consumption causes excessive drowsiness, so do not take alcohol while using Trivastal LA Tablet . Trivastal LA Tablet may cause sudden onset of drowsiness, so do not drive or operate heavy machinery.

Uses of Trivastal LA Tablet

Treatment of Parkinson's disease

Medicinal Benefits

Trivastal LA Tablet is an antiparkinson agent that is used in the treatment of Parkinson’s disease. In Parkinson’s patients, the nerve cells that produce dopamine (a chemical messenger that is important for movement control) begin to die. So, there is a decrease in dopamine levels. Trivastal LA Tablet increases dopamine levels in the brain, thereby improving the symptoms of Parkinson’s disease. Trivastal LA Tablet can also be used in the symptomatic treatment of brain and neurological disorders to improve cognitive skills (thinking and learning abilities), except in Alzheimer’s disease and other dementias. It is also used to treat intermittent claudication (sudden pain in the legs while walking or exercising), which occurs due to low blood flow to the legs, ocular ischemic symptoms (problems with blood flow to the eye), restless leg syndrome (an uncontrollable urge to move your legs while sitting or lying down), and depression.

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Trivastal LA Tablet

  • Nausea
  • Vomiting
  • Flatulence
  • Confusion
  • Hallucinations
  • Agitation
  • Dizziness
  • Drowsiness

Drug Warnings

Trivastal LA Tablet may cause sudden onset of drowsiness without any warning signs. However, it is very rarely seen in patients taking this medicine.  Trivastal LA Tablet may also cause orthostatic hypotension (sudden fall in blood pressure while rising from a sitting or lying position). If you notice impulse control disorders such as gambling addiction, increased libido (sexual desire), sexual addiction, compulsive spending or buying, and binge eating, inform your doctor immediately. In such cases, the doctor may reduce the dose or stop the treatment based on your condition. Do not discontinue treatment abruptly without discussing it with your doctor, as the Trivastal LA Tablet may cause withdrawal symptoms. Trivastal LA Tablet contains sucrose, so inform your doctor if you have glucose metabolism disorders or sugar intolerance.

Drug Interactions

Drug-Drug Interactions: Trivastal LA Tablet may interact with medicines used to treat psychosis or nausea and vomiting (chlorpromazine, prochlorperazine, fluphenazine, haloperidol, etc.) and medication used to treat movement disorders (tetrabenazine).

Drug-Food Interactions: Do not take alcohol, as it may increase drowsiness.

Drug-Disease Interactions: Trivastal LA Tablet should not be used in patients with cardiovascular shock (a serious condition in which the heart suddenly stops pumping blood), acute myocardial infarction (heart attack), other heart diseases, and diabetes or intolerance to sugars.

Drug-Drug Interactions Checker List

  • CHLORPROMAZINE
  • PROCHLORPERAZINE
  • FLUPHENAZINE
  • HALOPERIDOL
  • TETRABENAZINE

Habit Forming

No

Diet & Lifestyle Advise

 

  • A balanced diet is essential to show improvement in Parkinson's disease and includes grains and leafy foods as this food is rich in vitamins, fibres, and minerals. With this food, one should also include dairy items, protein-rich nourishments, for example, meat and beans, and solid fats found in nuts, olive oil, fish, and eggs in their diet. Limit the consumption of sugar-rich foods.
  • Constipation is a common issue for individuals with Parkinson's disease. Drinking more liquid and increasing fibre intake helps overcome this issue.
  • Parkinson's sickness is often caused by decreased bone thickness. In this manner, taking calcium and nutrient D enhancements may help. However, do not take any supplements before counselling a doctor.
  • Drink plenty of fluids to stay hydrated, as a person with this disease often feels dehydrated.

Special Advise

  • Stand up slowly while rising from a sitting or lying position to avoid orthostatic hypotension (sudden fall in blood pressure while rising up). 
  • Trivastal LA Tablet is usually preferred to take after food to avoid side effects associated with the stomach and intestine.

Disease/Condition Glossary

Parkinson's disease (PD): Parkinson's disease is also a movement disorder that mainly affects a person's ability to perform regular activities. It is a chronic and progressive disorder that can worsen with time if proper treatment is not provided at the right time. Some common symptoms faced by many persons include tremors at rest, stiffness of the limbs, slow movement, difficulty in movement or walking, and impaired balance. Other motor symptoms include trouble in solving problems, small handwriting, stooped posture, etc. This disease also affects the brain's ability to work properly, including sleep disturbances, reduced ability to smell, depression, fatigue, and anxiety. However, the symptoms of this disease vary from person to person. There are certain neurons present in the brain that are responsible for making dopamine. This neurotransmitter helps to regulate the movement of the body. Loss of dopamine is supposed to be the primary reason for the occurrence of Parkinson's disease.

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Alcohol

Caution

Trivastal LA Tablet may interact with alcohol as it causes excessive drowsiness.

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Pregnancy

Unsafe

There is no relevant data to establish the safe use of Trivastal LA Tablet in pregnant women as Trivastal LA Tablet is restricted for use in elderly patients.

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Breast Feeding

Unsafe

There is no relevant data to establish the safe use of Trivastal LA Tablet in breastfeeding mothers as Trivastal LA Tablet is restricted for use in elderly patients.

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Driving

Unsafe

Do not drive or operate heavy machinery as Trivastal LA Tablet may cause sudden onset of drowsiness.

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Liver

Caution

Trivastal LA Tablet may affect liver function when given in high doses. So, the dose may have to be adjusted by your doctor in patients with liver diseases.

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Kidney

Caution

There is no relevant data to establish the safe use of Trivastal LA Tablet in patients with kidney disease. So, it should be used with caution.

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Children

Unsafe

There is no relevant data to establish the safe use of Trivastal LA Tablet in children as Trivastal LA Tablet is restricted for elderly patients.

Country of origin

India

Manufacturer/Marketer address

Serdia House, Off Dr. S S Rao Road, Behind M G Hospital Parel, Mumbai 400012
Other Info - TRI0036

Author Details

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FAQs

Trivastal LA Tablet is used in the treatment of Parkinson's disease.
Trivastal LA Tablet contains 'Piribedil', which is used to treat Parkinson's disease. It increases dopamine levels, a chemical messenger in the brain that causes symptoms of Parkinson's disease.
Trivastal LA Tablet can cause drowsiness. Some patients taking this medicine may also experience a sudden onset of sleepiness without any warning signs. So, it would be best if you refrained from activities that require you to stay alert, such as driving or operating heavy machinery.
Before taking Trivastal LA Tablet , you should inform your doctor if you have hypertension or other heart diseases. However, Trivastal LA Tablet should not be used in patients with heart failure, or serious heart diseases.
Trivastal LA Tablet can be used to treat depression. However, you should not take this medicine for any indication without informing your doctor.
Trivastal LA Tablet may cause orthostatic hypotension (sudden fall in blood pressure while rising up), so stand up slowly while rising from a sitting or lying position. Trivastal LA Tablet is usually preferred to take after food to avoid side-effects associated with stomach and intestine. Inform your doctor if you notice any impulsive behaviours such as the urge to eat, gamble, spend money, or increased sexual desire. Trivastal LA Tablet may cause drowsiness, so do not drive or operate heavy machinery.
Inform the doctor about your health condition and medications you are taking. Let the doctor know if you are pregnant or breastfeeding.
Trivastal LA Tablet may not be recommended for people with cardiovascular shock (a serious condition in which the heart suddenly stops pumping blood) and acute myocardial infarction (heart attack). Consult the doctor if you have heart or blood pressure problems before starting Trivastal LA Tablet .
Do not take more than the prescribed dose of Trivastal LA Tablet as it may cause an overdose. Overdosage symptoms of Trivastal LA Tablet are low/high blood pressure, nausea, and vomiting. If you suspect you have taken an overdose, please consult a doctor immediately.
Trivastal LA Tablet may cause sudden onset of drowsiness, so do not drive or operate heavy machinery until you know how the medicine affects you.
The common side effects of Trivastal LA Tablet are nausea, vomiting, flatulence, agitation, dizziness, and drowsiness. These side effects usually improve after discontinuation of therapy. However, if any of these side effects persist or worsen during or after the treatment, inform your doctor immediately.

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