Tripcobal Tablet belongs to a group of medications known as 'anticonvulsants' used to manage neuropathic pain due to damaged nerves. Neuropathic pain is a chronic progressive nerve disease that causes nerve pain due to nerve damage or a malfunctioning nervous system. The pain could be intermittent or continuous, with a prickling, stabbing, tingling, or burning sensation. 

Tripcobal Tablet is a suspended-release tablet that combines two drugs: Mecobalamin (vitamin B12) and Amitriptyline (anticonvulsant). Mecobalamin (also known as methylcobalamin) is a form of Vitamin B12 required by the brain and nerves for producing red blood cells. Amitriptyline works by changing how nerves send messages to your brain. Together, Tripcobal Tablet helps to treat neuropathic pain (pain due to nerve damage). 

Take Tripcobal Tablet as prescribed by your doctor. Depending on your medical condition, you are advised to take Tripcobal Tablet for as long as your doctor has prescribed it for you. In some cases, you may experience common side effects such as nausea, vomiting, stomach pain, diarrhoea, loss of appetite, heartburn, dry mouth, dizziness, sleepiness, and uncoordinated body movements. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Do not take Tripcobal Tablet if you are pregnant or breastfeeding unless prescribed by the doctor. Tripcobal Tablet causes drowsiness and dizziness, so drive only if you are alert. Tripcobal Tablet should not be given to children as safety and effectiveness have not been established. Avoid consuming alcohol with Tripcobal Tablet as it could lead to increased dizziness and sleepiness. Keep your doctor informed about your health condition and medicines to rule out any side effects. Let your doctor know if you have a history of heart disease, severe kidney disease, disorders of the stomach or gut/bowel, and diabetes before using the Tripcobal Tablet . 

Tripcobal Tablet is a combination of two drugs: Methylcobalamin and Amitriptyline. Methylcobalamin is used to restore vitamin B12 in the body to treat damaged nerve conditions due to diabetes or other traumatic situations. It also has a neuroprotective activity that helps the nerve cells to function properly and treat neuropathic pain. On the other side, Amitriptyline prevents neuropathic pain (pain due to damaged nerves), fibromyalgia (musculoskeletal pain), and epilepsy (fits). It works by calming the damaged or overactive nerves in your body that may cause pain or seizures, thereby decreasing the number of pain signals sent out by damaged nerves in the body. Overall it reduces the pain which has been damaged or irritated due to conditions like chronic conditions, diabetes, trauma or epilepsy. Together, Tripcobal Tablet helps to treat neuropathic pain.

• Nausea
• Vomiting
• Stomach pain
• Diarrhoea
• Heartburn
• Dryness in mouth
• Dizziness
• Blurred vision

Do not take Tripcobal Tablet if you are allergic to any of its contents, if you recently had a heart attack or heart problems, are taking other antidepressants like isocarboxazid, phenelzine, selegiline, tranylcypromine or have taken them in the last 14 days, have severe liver disease or if you have taken moclobemide (used to treat depression and social anxiety). Inform your doctor before taking Tripcobal Tablet if you have heart rhythm problems or hypotension. Consult your doctor immediately if you have suicidal thoughts like killing or harming yourself. Do not take Tripcobal Tablet if you are pregnant or breastfeeding unless prescribed. Tripcobal Tablet causes drowsiness and dizziness, do not drive unless you are alert. Tripcobal Tablet can be given to children above six years if prescribed by the doctor for treating bedwetting. Tripcobal Tablet should not be given to children for treating depression or neuropathic pain. Avoid consuming alcohol with Tripcobal Tablet as it could lead to increased drowsiness and dizziness. Rise slowly from sitting or lying position as Tripcobal Tablet causes orthostatic hypotension (sudden lowering in blood pressure leading to dizziness on standing).

Drug-Drug Interactions: Tripcobal Tablet may interact with painkillers (tramadol, trazodone, hydrocodone, oxycodone, acetaminophen), an antidepressant (bupropion, duloxetine, fluoxetine, sertraline), antihistamine (diphenhydramine, cetirizine), sedatives (zolpidem), muscle relaxant (cyclobenzaprine), anti-convulsant (gabapentin, lamotrigine, escitalopram, pregabalin, topiramate), anti-thyroid (levothyroxine), and anti-anxiety (alprazolam).

Drug-Food Interactions: Avoid alcohol consumption while taking Tripcobal Tablet as it might cause increased dizziness and sleepiness.

Drug-Disease Interactions: Tripcobal Tablet may interact with disease conditions such as heart problems, anticholinergic effects, depression, seizure disorders, bone marrow suppression, diabetes, schizophrenia, bipolar disorder, acute alcohol intoxication, glaucoma, thyroid problems, pheochromocytoma, neutropenia, kidney and liver problems.

• TRAMADOL
• TRAZODONE
• HYDROCODONE
• OXYCODONE
• ACETAMINOPHEN
• BUPROPION
• DULOXETINE
• FLUOXETINE
• SERTRALINE
• DIPHENHYDRAMINE
• CETIRIZINE
• ZOLPIDEM
• CYCLOBENZAPRINE
• GABAPENTIN
• LAMOTRIGINE
• ESCITALOPRAM
• PREGABALIN
• TOPIRAMATE
• LEVOTHYROXINE

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• Include food rich in vitamins B and D in your diet.
• Include cayenne pepper in your diet to help lower neuropathic pain.
• Exercising regularly helps in improving overall health and combating pain.
• Rest well, and get plenty of sleep.
• Try taking a warm bath, as it can be soothing.
• Avoid smoking and alcohol consumption.
• Meditation and yoga can help lower stress, decrease pain sensitivity, and improves coping skills.
• Acupuncture can be helpful by stimulating pressure points.
• Using essential oils for massages can help increase circulation.
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•  Tripcobal Tablet can make you feel dizzy or drowsy, try to get up slowly while rising from a sitting or lying position.
• Tripcobal Tablet can cause dry mouth, so in that case, you can drink water or fluids, suck hard candy or ice, chew (sugarless) gum, or use a saliva substitute.

Neuropathic pain: Neuropathic pain is caused due to damage to sensory nerves. It is caused by chronic progressive nerve disease or due to infection or injury. The pain could be intermittent or continuous, which is felt as a prickling, stabbing, tingling, or burning sensation. A feeling of numbness and loss of sensations is also common with neuropathic pain. Usually, the body sends the pain signals when there is an injury, but with neuropathic pain, the pain is not triggered by an injury; the body unpromptedly sends the pain signals. Symptoms include spontaneous, untriggered pain, unpleasant feeling, shooting, burning or stabbing pain, difficulty resting or sleeping and evoked pain (pain caused by events usually not painful).