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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Nov 23, 2024 | 4:50 PM IST
Triolmesar 40 Tablet is used for lowering high blood pressure (hypertension) by removing extra fluid (electrolytes) from the body. It works by relaxing and widening the narrowed blood vessels. It reduces the heart's workload and makes it more efficient at pumping blood throughout the body. Also, it removes extra water/fluid and certain electrolyte overload from the body. Thus, it lowers fluid overload and high blood pressure, improves blood flow, and reduces the future risk of a heart attack and stroke. In some cases, it may cause common side effects such as nausea, upset stomach, dehydration, headache, diarrhoea, electrolyte imbalance, headache, feeling exhausted, swollen ankles, dizziness, and decreased blood pressure. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Manufacturer/Marketer

Macleods Pharmaceuticals Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Triolmesar 40 Tablet

Triolmesar 40 Tablet belongs to a group of medications called 'anti-hypertensives' primarily used for lowering high blood pressure (hypertension) by removing extra fluid (electrolytes) from the body. High blood pressure is a chronic condition in which the blood's force against the artery wall is high. As a result, it increases the risk of heart-related diseases like heart attack, heart failure, stroke, irregular heartbeat, and other complications.

Triolmesar 40 Tablet is a combination of three medicines: Olmesartan medoximil, Amlodipine, and Hydrochlorothiazide. Olmesartan medoximil is a prodrug and breaks down into active form, i.e., olmesartan once absorbed in the GIT (Gastrointestinal tract). An angiotensin receptor blocker (ARB) blocks the hormone angiotensin, thereby relaxing and widening the narrowed blood vessels. Amlodipine is a calcium channel blocker; it reduces the heart's workload and makes it more efficient at pumping blood throughout the body. Hydrochlorothiazide is a diuretic or water pill that removes extra water/fluid and certain electrolyte overload from the body. Together, Triolmesar 40 Tablet lowers fluid overload, raises blood pressure, improves blood flow, and reduces the future risk of a heart attack and stroke.

Depending upon your medical condition, you are advised to take Triolmesar 40 Tablet for as long as your doctor has prescribed it for you. The most common side effects of Triolmesar 40 Tablet are nausea, upset stomach, dehydration, headache, diarrhoea, electrolyte imbalance, headache, feeling exhausted, swollen ankles, dizziness, and decreased blood pressure in some cases. Most of these side effects of Triolmesar 40 Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Do not use potassium supplements or salt substitutes unless your doctor tells you. In rare cases, Triolmesar 40 Tablet can cause a condition that results in a skeletal muscle problem, leading to further kidney failure. If you notice unexplained muscle pain, dark-coloured urine, tenderness, or weakness, especially if you also have a fever or unexplained tiredness, immediately contact the doctor. Try not to stop taking this medicine of your own. Let your doctor know about this, as it may cause a rise in blood pressure and increase heart disease and stroke risk. Inform your doctor if you are suffering from kidney, liver, heart disease, or diabetes. If you are pregnant or breastfeeding, do not take Triolmesar 40 Tablet as it is a category D pregnancy drug and may harm the baby. Do not use the Triolmesar 40 Tablet if you cannot urinate, are dehydrated, have low blood pressure (hypotension), or have had cardiogenic shock (sudden stopping blood flow to the heart). Please tell your doctor if you are taking any other medicines or are allergic to this medicine. Reducing table salt (sodium chloride) in your food often helps lower blood pressure.

Uses of Triolmesar 40 Tablet

Treatment of Hypertension (high blood pressure)

Medicinal Benefits

Triolmesar 40 Tablet belongs to a group of medications called 'anti-hypertensives' primarily used for lowering high blood pressure (hypertension) by removing extra fluid (electrolytes) from the body. Triolmesar 40 Tablet is a combination of three medicines: Olmesartan medoximil, Amlodipine, and Hydrochlorothiazide. Olmesartan medoximil is a prodrug and breaks down into active form, i.e., olmesartan once absorbed in the GIT (Gastrointestinal tract). An angiotensin receptor blocker (ARB) blocks the hormone angiotensin, thereby relaxing and widening the narrowed blood vessels. Amlodipine is a calcium channel blocker; it reduces the heart's workload and makes it more efficient at pumping blood throughout the body. Hydrochlorothiazide is a diuretic or water pill that removes extra water/fluid and certain electrolyte overload from the body. Together, Triolmesar 40 Tablet lowers fluid overload, raises blood pressure, improves blood flow, and reduces the future risk of a heart attack and stroke.

Directions for Use

Swallow the medicine as a whole with water; do not crush, break or chew it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Triolmesar 40 Tablet

  • Nausea

  • Upset stomach

  • Dehydration

  • Headache

  • Dry mouth

  • Muscle cramps/weakness

  • Fast/slow/irregular heartbeat

  • Diarrhoea

  • Electrolyte imbalance

  • Headache

  • Feeling exhausted

  • Swollen ankles

  • Dizziness

  • Decreased blood pressure

Drug Warnings

Do not use Triolmesar 40 Tablet if you are pregnant, planning for pregnancy, or unable to urinate (anuria). If you have diabetes and taking Triolmesar 40 Tablet with other blood pressure-lowering pills like 'aliskiren,' immediately stop taking both together and consult a doctor. Besides this, it is contraindicated in low blood pressure (hypotension), cardiogenic shock (sudden stopping of blood flow to the heart), and aortic stenosis (heart valve problem). Triolmesar 40 Tablet may pass into breast milk, so before starting Triolmesar 40 Tablet , either you need to stop nursing or you should not take Triolmesar 40 Tablet while breastfeeding. Please inform your doctor before surgery if you are taking Triolmesar 40 Tablet as it needs to be stopped because it might lower the blood pressure further if taken along with local anaesthesia. Avoid potassium salt or its substitute intake while using Triolmesar 40 Tablet to avoid any electrolyte imbalance. Triolmesar 40 Tablet can pass into breast milk, but its effect on the baby is unknown. So, it is better to tell your doctor if you take Triolmesar 40 Tablet and breastfeeding.

Drug Interactions

Drug-drug interactions: Triolmesar 40 Tablet may interact with an antidepressant (lithium), heart rhythm controlling medicines (digoxin), blood thinner (aspirin), antidiabetic drugs (metformin, insulin), medications used to treat erectile dysfunction (sildenafil), medicines used to lower cholesterol levels (simvastatin), immunosuppressants (cyclosporine), and other anti-hypertensive medicines (atenolol, aliskiren, enalapril, lisinopril, ramipril, metoprolol), pain killers (ibuprofen), medicines for treating stomach ulcers (carbenoxolone).

Drug-food Interactions: Triolmesar 40 Tablet may interact with high potassium-containing food and drinks. So, if you are using any of the OTC items, please tell your doctor. Also, alcohol should not be consumed while taking Triolmesar 40 Tablet .

Drug-Disease Interactions: The efficacy of Triolmesar 40 Tablet is affected, and the disease condition may even worsen if taken in patients with a recent or history of heart attack, low blood pressure, low potassium level, low electrolytes (sodium, potassium, calcium, etc.), anuria (non-passage of urine), angioedema (an allergic condition with swelling under the skin), lupus (an autoimmune disease), kidney disease, liver disease, asthma, diabetes.

Drug-Drug Interactions Checker List

  • LITHIUM
  • DIGOXIN
  • ASPIRIN
  • METFORMIN
  • INSULIN
  • SILDENAFIL
  • SIMVASTATIN
  • CYCLOSPORINE
  • ATENOLOL
  • ALISKIREN
  • ENALAPRIL
  • LISINOPRIL
  • RAMIPRIL
  • METOPROLOL
  • IBUPROFEN
  • CARBENOXOLONE

Habit Forming

No

Diet & Lifestyle Advise

  • Create a well-balanced and healthy diet that includes vegetables, fruits, whole grains, legumes, omega-3-rich foods, and lean protein sources.

  • Keep your weight under control with a BMI of 19.5-24.9.

  • Avoid chronic stress, as it can raise your blood pressure.

  • Spend time with your loved ones to cope with stress and practice mindfulness techniques.

  • Be mindful of salt; consume no more than 2,300 mg each day.

  • Limit or avoid alcohol consumption.

  • Quitting smoking is the best strategy to lower the risk of heart disease.

Disease/Condition Glossary

Hypertension: It is a chronic condition when blood pressure is too high. This condition can lead to hardened arteries (blood vessels), decreasing the blood and oxygen flow to the heart. Blood pressure is the measurement of the force our heart uses to pump blood to all body parts. Raised blood pressure can cause chest pain (angina) and heart attack (when the blood supply to the heart is blocked). High blood pressure also causes brain damage (stroke) and kidney failure. High blood pressure can be diagnosed with the help of a blood pressure monitor or sphygmomanometer. Systolic pressure is the pressure when the heart pumps blood out. On the other hand, diastolic pressure is when your heart is at the resting stage between heartbeats. If your blood pressure is 140/90 mm of Hg, it means the systolic pressure is 140 mm of Hg, and diastolic pressure is 90 mm of Hg. Ideal blood pressure should be between 90/60 mm of Hg and 120/80 mm of Hg.

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Alcohol

Unsafe

You are recommended not to consume alcohol and Triolmesar 40 Tablet to avoid unpleasant side effects like drowsiness, dizziness, and liver damage.

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Pregnancy

Unsafe

Triolmesar 40 Tablet is not recommended during pregnancy as it contains Olmesartan, which is a category D pregnancy drug. This medicine may cause fetal damage and can affect the unborn baby (fetus).

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Breast Feeding

Unsafe

Triolmesar 40 Tablet is known to pass breast milk, but its effect on the baby is unknown. So, before breastfeeding, let your doctor know about this. Either you need to stop breastfeeding for using Triolmesar 40 Tablet or stop taking Triolmesar 40 Tablet .

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Driving

Caution

Drive with caution; Triolmesar 40 Tablet usually causes drowsiness and affects driving ability.

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Liver

Caution

Triolmesar 40 Tablet to be taken with caution, especially if you have or have had a history of liver disease. Your doctor will have to change the dosage depending on your medical condition and your reaction to treatment.

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Kidney

Caution

Triolmesar 40 Tablet to be taken with caution, especially if you have had a history of kidney disease. Your doctor will have to change the dosage depending on your medical condition and your reaction to treatment.

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Children

Caution

Efficacy and safety of Triolmesar 40 Tablet have not been established in children. If prescribed, it should be strictly under medical supervision and only if the benefits outweigh the harm.

Country of origin

India

Manufacturer/Marketer address

Atlanta Arcade, Marol Church Road, Andheri (East), Mumbai - 400059, INDIA.
Other Info - TRI0608

Author Details

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FAQs

Triolmesar 40 Tablet is used for lowering high blood pressure (hypertension) by removing extra fluid (electrolytes) from the body.
Triolmesar 40 Tablet is a combination of three medicines: Olmesartan medoximil, Amlodipine, and Hydrochlorothiazide. Olmesartan medoximil relaxes and widens the narrowed blood vessels. Amlodipine reduces the heart's workload and makes the heart more efficient at pumping blood throughout the body. Hydrochlorothiazide is a diuretic or water pill that removes extra water/fluid and certain electrolyte overload from the body. Together, Triolmesar 40 Tablet lowers fluid overload, raises blood pressure, improves blood flow, and reduces the future risk of a heart attack and stroke.
Triolmesar 40 Tablet can be safely taken as long as your doctor prescribes it. Conditions such as high blood pressure are life-long conditions, and one should not abruptly discontinue it without discussing it with a doctor. Discontinuing Triolmesar 40 Tablet may lead to increased blood pressure and a high risk of heart attack and stroke.
It's unlikely that Triolmesar 40 Tablet affects fertility in men or women. However, in some cases, some water pills like hydrochlorothiazide may lead to erectile dysfunction. For the best advice, please consult your doctor.
Please inform your doctor before surgery if you are taking Triolmesar 40 Tablet as it needs to be stopped because it might lower the blood pressure further if taken along with local anaesthesia.
Do not use Triolmesar 40 Tablet if you are pregnant, planning for pregnancy, or unable to urinate. If you have diabetes and taking Triolmesar 40 Tablet with other blood pressure-lowering pills like 'aliskiren', immediately stop taking both together and consult a doctor.
High blood pressure during pregnancy is called 'Pregnancy-induced hypertension (PIH). It is harmful to both the baby and the mother. In the mother, very high blood pressure can cause seizures (fits), headache, swelling of feet, kidney damage, and a higher risk of bleeding during pregnancy and delivery. This can also affect the baby by causing abnormal fetal heart rate, risk of stillbirth, and a small baby. So, during pregnancy, you should have regular blood pressure monitoring. Visit your Obstetrician if you have any concerns about blood pressure during pregnancy.
Yes, Triolmesar 40 Tablet is known to cause ankle swelling (oedema) upon long-term use as Triolmesar 40 Tablet amlodipine. Please try to keep your feet up when sitting for long hours. If the problem persists still, consult your doctor and do as advised.
Triolmesar 40 Tablet can be taken with or without food or as advised by the doctor.
You are not recommended to stop Triolmesar 40 Tablet , as stopping it may raise blood pressure and increase the risk of heart disease and stroke. Therefore, inform your doctor if you intend to stop taking Triolmesar 40 Tablet or if you experience any difficulty while taking Triolmesar 40 Tablet .
To control high blood pressure, it’s important to follow a balanced diet that includes proteins, whole grains, and fiber-rich fruits and vegetables. Limit your intake of carbohydrates, salt, and sugar. Before making any changes to your diet or eating habits, consult your doctor. Regular exercise and weight loss are also recommended. Avoid smoking and drinking.
You may observe a decrease in your blood pressure within 2 weeks of starting Triolmesar 40 Tablet . But to notice the full effects of Triolmesar 40 Tablet , it may take up to 8 weeks.
You are recommended to take the first dose before bedtime, as Triolmesar 40 Tablet can cause dizziness. After the first dose, you can take Triolmesar 40 Tablet at any time of day, but it’s essential to take it at the same time each day for consistency and to help you remember.
You may feel dizzy after taking Triolmesar 40 Tablet as it is one of its side effects. Avoid driving if you feel dizzy. This condition doesn’t require any medical treatment as it will gradually reduce over time. Consult your doctor, if the condition persists longer.
Triolmesar 40 Tablet does not usually cause weight gain. Change your lifestyle and maintain a balanced diet if you observe any changes in your weight. However, in rare cases, chronic diarrhoea with weight loss may occur. If the patient experiences diarrhoea while taking Triolmesar 40 Tablet and the cause is unknown, consult a doctor.
Triolmesar 40 Tablet includes side effects such as painful joints, fast heartbeat, skin rash or itchiness, chest tightness, shortness of breath, weak muscles, swelling of feet, hands, or ankles. Please, consult your doctor if you experience any of these side effects.
Take the Triolmesar 40 Tablet whole with a glass of water; do not crush or chew it. To help you remember, try to take it at the same time every day.
Before taking Triolmesar 40 Tablet , inform your doctor if you have kidney, liver or heart disease, diabetes, or asthma. Also, let your doctor know about all the medications you might be taking.
You are recommended to be cautious while driving or operating machinery after taking Triolmesar 40 Tablet as it may cause drowsiness which affects the driving ability.
Inform your doctor about all the medications you are currently taking, as Triolmesar 40 Tablet may interact with other drugs, potentially causing harmful reactions. It may interact with medications such as antidepressants (lithium), heart rhythm drugs (digoxin), blood thinners (aspirin), antidiabetics (metformin, insulin), erectile dysfunction treatments (sildenafil), cholesterol-lowering drugs (simvastatin), immune-suppressants (cyclosporine), other anti-hypertensives (atenolol), pain relievers (ibuprofen), and ulcer medications (carbenoxolone).

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