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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
Trilavir E Tablet belongs to the class of antiretroviral drugs used in the treatment of HIV infection. This combination medicine work by inhibiting the reverse transcriptase enzyme production, which is necessary for the multiplication of the viruses. Common side effects include dizziness, headache, diarrhoea, nausea, vomiting, rashes, and feeling weak
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About Trilavir E Tablet

Trilavir E Tablet belongs to the class of medicines called ‘antiretroviral agents’ used to treat HIV infection. HIV is a virus that attacks the immune cells of the body leading to decreased immunity. It spreads through body fluids such as semen, vaginal fluid, and blood. Symptoms include fever, chills, rash, night sweats, muscle aches, tiredness, and sore throat that usually last for days to several weeks.

Trilavir E Tablet contains Emtricitabine, Tenofovir Disoproxil Fumarate and Efavirenz. Efavirenz is a non-nucleoside reverse transcriptase inhibitor, Emtricitabine is a nucleoside reverse transcriptase inhibitor, and Tenofovir Disoproxil Fumarate is a nucleotide reverse transcriptase inhibitor. They work by inhibiting the reverse transcriptase enzyme production, which is necessary for the multiplication of the viruses. This effect helps to inhibit viral replication.

You should take this medicine exactly as prescribed by the doctor. The common side-effects of Trilavir E Tablet are dizziness, headache, diarrhoea, nausea, vomiting, rashes (red spots or blotches, sometimes with blistering and swelling of the skin), and feeling weak. These side effects usually resolve without requiring any medical attention. However, if any of these side effects persist or worsen, inform your doctor immediately.

Trilavir E Tablet is not recommended to take Trilavir E Tablet if you are allergic to any contents of it. Trilavir E Tablet is not recommended for use in lactating mothers, children and adolescents under 18 years of age. Trilavir E Tablet may cause dizziness, so do not drive or operate heavy machinery if you feel dizzy. Consumption of alcohol may increase the risk of side effects; therefore, avoid alcohol consumption.

Uses of Trilavir E Tablet

Treatment of HIV infection

Directions for Use

Trilavir E Tablet should be swallowed as a whole with a glass of water. Do not crush, chew, or break it. It should be taken on an empty stomach 1 hour before or 2 hours after a meal, preferably at bedtime. Your doctor will prescribe the dose and duration based on your health condition.

Medicinal Benefits

Trilavir E Tablet belongs to the group of medicines called antiretroviral therapy. Trilavir E Tablet contains Emtricitabine, Tenofovir Disoproxil Fumarate and Efavirenz. Trilavir E Tablet works by inhibiting the reverse transcriptase enzyme production, which is necessary to multiply the viruses. This effect helps to inhibit viral replication and treats HIV infection.

How Trilavir E Tablet Works

Trilavir E Tablet contains Emtricitabine, Tenofovir Disoproxil Fumarate and Efavirenz. Efavirenz is a non-nucleoside reverse transcriptase inhibitor, Emtricitabine is a nucleoside reverse transcriptase inhibitor, and Tenofovir Disoproxil Fumarate is a nucleotide reverse transcriptase inhibitor. They work by inhibiting the reverse transcriptase enzyme production, which is necessary for the multiplication of the viruses. This effect helps to inhibit viral replication.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Trilavir E Tablet

  • Dizziness
  • Headache
  • Diarrhoea
  • Nausea
  • Vomiting
  • Rashes
  • Feeling weak
  • Loss of appetite

What if I have taken an overdose of Trilavir E Tablet

Take Trilavir E Tablet only as prescribed by the physician. Avoid exceeding the recommended dose as it could lead to an overdose. Symptoms of overdose may include uncontrolled body movements, dizziness, difficulty concentrating, nervousness, confusion, forgetfulness, difficulty falling asleep or staying asleep, unusual dreams, drowsiness, hallucinations (seeing things or hearing voices that do not exist), abnormally happy mood, and strange thoughts. If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

Trilavir E Tablet should be used with caution in patients with mental illness, fits, and liver diseases. If you notice any signs of infection, inform your doctor immediately. Autoimmune diseases (immune cells attack healthy body tissue) may occur months after the start of the treatment. Inform your doctor if you notice any signs such as muscle weakness, weakness in the hands and feet, palpitations (pounding heart), and tremors. Trilavir E Tablet may cause osteonecrosis (death of bone tissue due to a decrease in blood supply to the bone) in some patients. The risk of this disease depends on factors such as length of antiretroviral therapy, alcohol use, steroid use, body mass index (BMI), and immunity. Inform your doctor if you notice joint pain, stiffness, and difficulty in movement, as these symptoms may indicate osteonecrosis.

Drug-Drug Interactions

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Tenofovir disoproxilDidanosine
Critical
Tenofovir disoproxilStreptozocin
Critical

Drug-Drug Interactions

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Tenofovir disoproxilDidanosine
Critical
How does the drug interact with Trilavir E Tablet:
Coadministration of Didanosine with Trilavir E Tablet can increase the levels and risk of Didanosine side effects.

How to manage the interaction:
Taking Didanosine with Trilavir E Tablet is not recommended, please consult your doctor before taking it. It can be taken if your doctor prescribes it. However, if you experience severe headaches, confusion, weakness, trouble walking, muscle pain, or high fever, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
Tenofovir disoproxilStreptozocin
Critical
How does the drug interact with Trilavir E Tablet:
Combining Trilavir E Tablet and Streptozocin can increase the risk of kidney problems.

How to manage the interaction:
Taking Trilavir E Tablet with Streptozocin is not recommended, as it can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not stop using any medications without talking to your doctor.
EfavirenzVoriconazole
Critical
How does the drug interact with Trilavir E Tablet:
Coadministration of Voriconazole with Trilavir E Tablet can alter the blood levels and effects of both medications.

How to manage the interaction:
Taking Voriconazole with Trilavir E Tablet can be taken if a doctor has advised it. Contact a doctor if you experience vomiting, dizziness, difficulty concentrating. Do not discontinue any medications without consulting a doctor.
EfavirenzErgometrine
Critical
How does the drug interact with Trilavir E Tablet:
When Trilavir E Tablet is taken with Ergometrine, the level of Ergometrine in the body can go up. This can increase the risk or severity of side effects.

How to manage the interaction:
Taking Ergometrine with Trilavir E Tablet is not recommended as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience nausea, vomiting, abdominal pain, diarrhea, headache, dizziness, ringing of the ears, chest pain, palpitation, or irregular heartbeats contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
EfavirenzCarbamazepine
Critical
How does the drug interact with Trilavir E Tablet:
Using carbamazepine together with Trilavir E Tablet may reduce the effect of carbamazepine.

How to manage the interaction:
Taking Trilavir E Tablet with Carbamazepine can result in an interaction, it can be taken if your doctor has advised it. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without talking to a doctor.
EfavirenzZiprasidone
Critical
How does the drug interact with Trilavir E Tablet:
Using ziprasidone together with Trilavir E Tablet can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Trilavir E Tablet with Ziprasidone is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
EfavirenzDienogest
Critical
How does the drug interact with Trilavir E Tablet:
When Trilavir E Tablet is taken with Dienogest, it can lower the metabolism of Dienogest and increase the risk or severity of side effects.

How to manage the interaction:
Taking Trilavir E Tablet with Dienogest can possibly result in an interaction, however, it can be taken when advised by a doctor. Do not stop using any medications without talking to a doctor.
EfavirenzGrepafloxacin
Critical
How does the drug interact with Trilavir E Tablet:
Taking Trilavir E Tablet with Grepafloxacin can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Trilavir E Tablet with Grepafloxacin together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
EfavirenzLomitapide
Critical
How does the drug interact with Trilavir E Tablet:
When Trilavir E Tablet is taken with Lomitapide it can increase the risk or severity of liver damage.

How to manage the interaction:
Taking Trilavir E Tablet with Lomitapide is not recommended as it results in an interaction, it can be taken if your doctor has advised it. However, if you notice any symptoms of fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark-colored urine, light-colored stools, and/or yellowing of the skin or eyes, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
EfavirenzRilpivirine
Critical
How does the drug interact with Trilavir E Tablet:
Taking Rilpivirine with Trilavir E Tablet can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Rilpivirine with Trilavir E Tablet together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat a healthy and balanced diet. Consume vitamin and nutrient-rich food such as vegetables and fruits as it helps to boost your immune system. Opt for lean protein and whole grains.
  • Avoid eating raw meat and eggs. Consume properly boiled and cooked meat, poultry, or seafood.
  • Eat bland and low-fat foods, and avoid spicy or oily foods if you experience nausea or vomiting.
  • Try to reduce emotional and physical stress by spending time with your family or doing whatever makes you happy.
  • Drink more fluids and avoid alcoholic beverages to prevent dehydration.
  • Make sure you sleep at least 8 hours a day.

Habit Forming

No

Therapeutic Class

ANTIRETROVIRAL AGENTS

Trilavir E Tablet Substitute

Substitutes safety advice
  • Trustiva Tablet 30's

    103.87per tablet
  • Tofoday 200 mg/300 mg/600 mg Tablet

    118.37per tablet
  • Timeovir-EM Tablet

    101.13per tablet
  • Teefamc 200mg/300mg/600mg Tablet

    106.38per tablet
  • Teefavir Tablet

    91.57per tablet
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Alcohol

Caution

Avoid the consumption of alcohol as it may increase the risk of side effects.

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Pregnancy

Caution

Trilavir E Tablet should be used with caution in pregnant women. It is given only if clinically needed and when the benefits outweigh the risk.

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Breast Feeding

Caution

Avoid breastfeeding during treatment with Trilavir E Tablet. Please seek medical advice if you have any concerns.

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Driving

Caution

Trilavir E Tablet may cause dizziness, so do not drive or operate heavy machinery if you feel dizzy.

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Liver

Caution

Trilavir E Tablet should not be used in patients with severe liver diseases. In mild to moderate conditions, the dose may have to be adjusted by your doctor as required.

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Kidney

Caution

Trilavir E Tablet should not be used in patients with moderate to severe kidney diseases as this medicine may affect kidney function. In mild conditions, the dose may have to be adjusted by your doctor as required.

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Children

Unsafe

Trilavir E Tablet is not recommended for children and adolescents below 18 years old.

FAQs

Trilavir E Tablet belongs to the class of medicines called antiretroviral agents used to treat HIV infection.
Trilavir E Tablet works by inhibiting the reverse transcriptase enzyme production, which is necessary for the production of viruses. This effect helps to inhibit viral replication and treats HIV infection.
Trilavir E Tablet is not recommended for patients with severe liver disease, moderate to severe kidney disease, or heart conditions such as prolonged QT interval, which increases the risk of severe heart rhythm problems, family history of heart problems, and low electrolyte levels.
Trilavir E Tablet doesn’t cure HIV infection. However, it helps to control the disease and prevent opportunistic infections.
Trilavir E Tablet may cause dizziness, drowsiness, difficulty sleeping, or difficulty concentrating in the first 1-2 days of treatment, and these symptoms generally go away after the first 2-4weeks. Therefore, avoid driving or operating machinery unless you are alert.

Country of origin

India
Other Info - TR10686

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