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Written By Veda Maddala , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
Trigabantin 300 Tablet is a combination medicine used to manage neuropathic pain due to damaged nerves. This medicine works by altering the nerve signals that cause pain and thereby protects nerve fibres. It helps provide a protective effect on the nerve tissues and the brain. You may experience common side effects like dizziness, sleepiness, tiredness, headache, nausea, vomiting, dry mouth, and constipation.
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Manufacturer/Marketer :

Sun Pharmaceutical Industries Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

Jan-27

About Trigabantin 300 Tablet

Trigabantin 300 Tablet is used to treat neuropathic pain. Neuropathic pain is a chronic progressive nerve disease that causes nerve pain due to damaged sensory nerves. Symptoms include spontaneous, untriggered pain, unpleasant feeling, shooting, burning or stabbing pain, difficulty resting or sleeping and evoked pain (pain caused by events that are usually not painful). Trigabantin 300 Tablet may be used in the treatment of diabetic neuropathy, drug-induced neuropathy, alcoholic neuropathy, and trigeminal neuralgia.

Trigabantin 300 Tablet contains Gabapentin (anti-convulsant), mecobalamin (vitamin B12), and alpha-lipoic acid (antioxidant). Gabapentin modulates the calcium channel activity of the brain cells, thereby decreasing pain. Mecobalamin helps rejuvenate and protect damaged nerve cells by producing a substance called myelin. Alpha-lipoic acid helps provide a protective effect on the nerve tissues and the brain. Together, Trigabantin 300 Tablet helps provide relief from neuropathic pain caused due to nerve damage and other neurological disorders. 
 
Take Trigabantin 300 Tablet for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side effects such as dizziness, sleepiness, tiredness, nausea and vomiting. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
 
Consult your doctor before starting Trigabantin 300 Tablet if you are pregnant or breastfeeding. Trigabantin 300 Tablet may cause drowsiness and dizziness, so drive only if you are alert. Limited information is available regarding the usage of Trigabantin 300 Tablet in children; please consult a doctor. Avoid consuming alcohol along with Trigabantin 300 Tablet as it could lead to increased dizziness and sleepiness. Keep your doctor informed about your health condition and medicines to rule out any side effects.

Uses of Trigabantin 300 Tablet

Treatment of Neuropathic pain

Directions for Use

Swallow it as a whole with a glass of water; do not chew, crush or break it.

Medicinal Benefits

Trigabantin 300 Tablet is a combination of three drugs: Gabapentin (anti-convulsant), Mecobalamin (vitamin B12), and Alpha-lipoic acid (antioxidant). Trigabantin 300 Tablet is used to treat neuropathic pain. Gabapentin modulates the calcium channel activity of the brain cells, thereby decreasing pain. Mecobalamin helps rejuvenate and protect damaged nerve cells by producing a substance called myelin. Alpha-lipoic acid helps in providing a protective effect on the nerve tissues and the brain. Together, Trigabantin 300 Tablet helps in providing relief from neuropathic pain.

How Trigabantin 300 Tablet Works

Trigabantin 300 Tablet contains Gabapentin (anti-convulsant), mecobalamin (vitamin B12), and alpha-lipoic acid (antioxidant). Gabapentin modulates the calcium channel activity of the brain cells, thereby decreasing pain. Mecobalamin helps rejuvenate and protect damaged nerve cells by producing a substance called myelin. Alpha-lipoic acid helps provide a protective effect on the nerve tissues and the brain. Together, Trigabantin 300 Tablet helps provide relief from neuropathic pain caused due to nerve damage and other neurological disorders.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Trigabantin 300 Tablet

  • Dizziness
  • Sleepiness
  • Tiredness
  • Nausea
  • Vomiting

What if I have taken an overdose of Trigabantin 300 Tablet

Avoid exceeding the recommended dose as it might cause an overdose. Consult the doctor if you suspect you have taken an overdose or experience any unusual symptoms.

Drug Warnings

Do not take Trigabantin 300 Tablet if you are allergic to any of its contents. Inform your doctor before taking Trigabantin 300 Tablet if you have heart problems or bipolar syndrome, nervous system disorders, or are older than 65. Consult your doctor if you are on haemodialysis and experience muscle pain or weakness, persistent stomach pain, nausea or vomiting. Please do not stop taking Trigabantin 300 Tablet without consulting your doctor, as it could cause withdrawal symptoms. Consult your doctor if you are pregnant or breastfeeding. Trigabantin 300 Tablet causes drowsiness and dizziness, so drive only if you are alert. Avoid consuming alcohol along with Trigabantin 300 Tablet as it could lead to increased dizziness and sleepiness. Consult your doctor immediately if you experience suicidal tendencies. 

Drug-Drug Interactions

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GabapentinBuprenorphine
Severe
GabapentinPethidine
Severe

Drug-Drug Interactions

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GabapentinBuprenorphine
Severe
How does the drug interact with Trigabantin 300 Tablet 10's:
Co-administration of Buprenorphine and Trigabantin 300 Tablet 10's may cause central nervous system depression and lead to serious side effects (respiratory distress -build-up of fluid in the air sacs of the lungs).

How to manage the interaction:
Although there is a possible interaction between Trigabantin 300 Tablet 10's and Buprenorphine, you can take these medicines together if prescribed by a doctor. However, if you experience shortness of breath, fast heart rate, fast breathing, extreme tiredness, fever, cough with phlegm, or shallow breaths, consult the doctor immediately. Do not discontinue any medications without a doctor's advice.
GabapentinPethidine
Severe
How does the drug interact with Trigabantin 300 Tablet 10's:
Combining Meperidine with Trigabantin 300 Tablet 10's can increase the risk of CNS depression.

How to manage the interaction:
Co-administration of Pethidine with Trigabantin 300 Tablet 10's can possibly result in an interaction, but it can be taken if a doctor has advised it. Do not stop using any medications without a doctor's advice.
GabapentinSodium oxybate
Severe
How does the drug interact with Trigabantin 300 Tablet 10's:
Taking Trigabantin 300 Tablet 10's with Sodium oxybate can increase the side effects on the central nervous system.

How to manage the interaction:
Although taking Trigabantin 300 Tablet 10's and Sodium oxybate together can evidently cause an interaction, it can be taken if a doctor has suggested it. If you notice any of these signs - feeling tired, dizzy, lightheaded, confused, sad, having low blood pressure, or difficulty breathing - make sure to contact your doctor right away. Do not stop using any medications without talking to a doctor.
GabapentinFentanyl
Severe
How does the drug interact with Trigabantin 300 Tablet 10's:
Taking fentanyl with other drugs that cause central nervous system depression, such as Trigabantin 300 Tablet 10's, might result in an increased risk of adverse effects.

How to manage the interaction:
Although combining Fentanyl and Trigabantin 300 Tablet 10's may cause an interaction, they can be used if advised by your doctor. Consult your doctor immediately if you feel drowsiness, trouble breathing, dizziness, or confusion. If you have any of the above symptoms, it is advised not to drive or use any hazardous machinery. Do not stop taking any medication without consulting your doctor.
GabapentinOxycodone
Severe
How does the drug interact with Trigabantin 300 Tablet 10's:
Combining Oxycodone with Trigabantin 300 Tablet 10's can increase the risk of CNS depression.

How to manage the interaction:
Taking Trigabantin 300 Tablet 10's with Oxycodone together can possibly result in an interaction, but it can be taken if a doctor has advised it. If you notice any symptoms like trouble breathing, dizziness, or trouble focusing, make sure to contact a doctor right away. Do not stop using any medications without a doctor's advice.
GabapentinCodeine
Severe
How does the drug interact with Trigabantin 300 Tablet 10's:
Combining Codeine with Trigabantin 300 Tablet 10's can increase the risk of CNS depression.

How to manage the interaction:
Taking Trigabantin 300 Tablet 10's with Codeine together can possibly result in an interaction, but it can be taken if a doctor has advised it. If you notice any symptoms like trouble breathing, feeling dizzy or tired, or having trouble focusing, make sure to contact a doctor right away. Do not stop using any medications without a doctor's advice.
GabapentinSufentanil
Severe
How does the drug interact with Trigabantin 300 Tablet 10's:
Combining Sufentanil with Trigabantin 300 Tablet 10's can increase the risk of CNS depression.

How to manage the interaction:
There may be a possibility of interaction between Trigabantin 300 Tablet 10's and Sufentanil, but it can be taken if prescribed by a doctor. It's important to keep an eye on your health and talk to a doctor about any concerns. They can recommend different options that won't cause any problems. If you notice any symptoms like trouble breathing, feeling dizzy or tired, or having trouble focusing, make sure to call your doctor right away. Do not discontinue any medications without first consulting your doctor.
GabapentinHydrocodone
Severe
How does the drug interact with Trigabantin 300 Tablet 10's:
When Hydrocodone is taken with Trigabantin 300 Tablet 10's, the amount of Hydrocodone in the blood may be reduced.

How to manage the interaction:
Although there is a possible interaction between Trigabantin 300 Tablet 10's and Hydrocodone, you can take these medicines together if prescribed by a doctor. If you notice any symptoms like trouble breathing, dizziness, or trouble focusing, make sure to contact a doctor right away. Do not stop using any medications without a doctor's advice.
GabapentinRemifentanil
Severe
How does the drug interact with Trigabantin 300 Tablet 10's:
Combining Remifentanil with Trigabantin 300 Tablet 10's can increase the risk of side effects.

How to manage the interaction:
Taking Trigabantin 300 Tablet 10's with Remifentanil together can possibly result in an interaction, but it can be taken if a doctor has advised it. If you notice any symptoms like trouble breathing, dizziness, or trouble focusing, make sure to contact a doctor right away. Do not discontinue any medications without consulting a doctor.
GabapentinKetamine
Severe
How does the drug interact with Trigabantin 300 Tablet 10's:
Using Ketamine together with Trigabantin 300 Tablet 10's may increase side effects.

How to manage the interaction:
Although taking Ketamine and Trigabantin 300 Tablet 10's together can evidently cause an interaction, it can be taken if a doctor has suggested it. If you start feeling dizzy, tired, confused, have trouble focusing, feel very sleepy, or have trouble breathing, make sure to call a doctor right away. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Include food rich in vitamins B and D in your diet as they can help improve nerve health and prevent nerve pain.

  • Include cayenne pepper in your diet, as it can help in lowering neuropathic pain.

  • Exercising regularly helps in improving overall health and combating pain. 

  • Rest well, and get plenty of sleep.

  • Try taking a warm bath, as it can be soothing. It helps in increasing blood circulation, thereby decreasing numbness and pain.

  • Avoid smoking and alcohol consumption.

  • Meditation and yoga can help lower stress, decrease pain sensitivity and improves coping skills.

  • Physical relaxation and massages can help provide symptomatic relief.

  • Learn about sitting, stretching, moving, and standing techniques from a physical or occupational therapist. These can help prevent pain.

  • Acupuncture can be helpful by stimulating pressure points.

  • Using essential oils for massages can help increase circulation and boosts healing.

Habit Forming

No

Therapeutic Class

MISCELLANEOUS
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Alcohol

Unsafe

Avoid consumption of alcohol while taking Trigabantin 300 Tablet as it may increase dizziness and sleepiness.

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Pregnancy

Consult your doctor

Please consult your doctor if you are pregnant before taking Trigabantin 300 Tablet ; your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Consult your doctor

Consult your doctor before taking Trigabantin 300 Tablet if you are breastfeeding; your doctor will decide whether Trigabantin 300 Tablet can be taken by breastfeeding mothers or not.

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Driving

Unsafe

Trigabantin 300 Tablet causes drowsiness, sleepiness and tiredness. Do not drive or operate machinery unless you are alert after taking Trigabantin 300 Tablet .

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Liver

Caution

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Consult your doctor

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Consult your doctor

Limited information is available regarding the usage of Trigabantin 300 Tablet in children. Please consult a doctor if you have any concerns.

FAQs

Trigabantin 300 Tablet is used to treat neuropathic pain.
Trigabantin 300 Tablet contains Gabapentin, Mecobalamin, and Alpha-lipoic acid. Gabapentin modulates the calcium channel activity of the brain cells, thereby decreasing pain. Mecobalamin helps rejuvenate and protect damaged nerve cells by producing a substance called myelin. Alpha-lipoic acid protects the nerve tissues and brain. Together, Trigabantin 300 Tablet helps treat neuropathic pain.
Do not discontinue Trigabantin 300 Tablet without consulting your doctor, as it could lead to withdrawal symptoms. To treat your condition effectually, continue taking Trigabantin 300 Tablet for as long as prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking Trigabantin 300 Tablet ; your doctor will reduce the dose gradually.
People taking Trigabantin 300 Tablet should be closely monitored for suicidal thoughts or behaviour. Do not be reluctant to speak with your doctor immediately if you experience suicidal tendencies.
Trigabantin 300 Tablet contains gabapentin which may interfere with laboratory test results. Inform the person doing the tests that you are taking Trigabantin 300 Tablet .
If Trigabantin 300 Tablet is taken along with antacid medicines containing aluminium and magnesium, it may lower the absorption of Trigabantin 300 Tablet from the stomach. To avoid this, maintain a gap of two hours between Trigabantin 300 Tablet and antacid medicines.
Trigabantin 300 Tablet may cause weight gain due to an increase in appetite. Maintain a healthy weight by regular exercise and following a balanced diet.

Country of origin

India

Manufacturer/Marketer address

Sun Pharmaceutical Industries Ltd., SUN HOUSE, CTS No. 201 B/1, Western Express Highway, Goregaon (E), Mumbai 400063
Other Info - TRI0013

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