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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 9, 2024 | 12:36 PM IST
Trigaan Injection 30 ml is used to treat functional bowel or irritable bowel syndrome (IBS). It contains Dicyclomine, also known as Dicycloverine. Dicyclomine belongs to the class of ‘anticholinergic/anti-muscarinic agents’ with antispasmodic activity. It blocks the activity of acetylcholine (acetylcholine is a neurotransmitter that sends signals to nerve cells) by binding to muscarinic receptors on smooth muscle. This process helps relax smooth muscles and inhibits natural gut movements. Thus, it prevents spasms in the muscles of the stomach and intestine.
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Composition

DICYCLOMINE-10MG

Manufacturer/Marketer

Tamman Titoe Pharma Pvt Ltd

Consume Type

PARENTERAL

Return Policy

Not Returnable

for this medicine

About Trigaan Injection 30 ml

Trigaan Injection 30 ml is used to treat functional bowel or irritable bowel syndrome (IBS). Trigaan Injection 30 ml reduces spasms (sudden involuntary contraction) of the muscles in the stomach and intestines. Irritable bowel syndrome is an intestinal disorder that causes stomach pain, wind, constipation, and diarrhoea.

Trigaan Injection 30 ml contains ‘Dicyclomine,’ also known as Dicycloverine. Dicyclomine belongs to the class of ‘anticholinergic/anti-muscarinic agents’ with antispasmodic activity. Trigaan Injection 30 ml blocks the activity of acetylcholine (acetylcholine is a neurotransmitter that sends signals to nerve cells) by binding to muscarinic receptors on smooth muscle. This process helps relax smooth muscles and inhibits natural gut movements. Thus, it prevents spasms in the muscles of the stomach and intestine.

Trigaan Injection 30 ml will be administered by a healthcare professional. Your doctor will advise the appropriate dose based on your medical condition. It shows common side effects like dizziness, drowsiness, light-headedness, weakness, nervousness, blurred vision, dry mouth, nausea, constipation, and trouble sleeping. These side effects may not occur in every patient using this medication and differ individually. If the side effects persist longer or worsen, please consult your doctor.

Let your doctor know if you are allergic to any medications. Inform your doctor if you have liver, kidney, heart disease, or other medical histories before receiving Trigaan Injection 30 ml. Some antacids may inhibit the absorption of Trigaan Injection 30 ml; hence, maintain a time gap between the intake of antacids and Trigaan Injection 30 ml. Trigaan Injection 30 ml may cause blurred vision, dizziness and drowsiness; hence, do not drive or operate machinery until you feel better. Let your doctor know if you are pregnant and breastfeeding before taking Trigaan Injection 30 ml. This medicine is not recommended for children below six months of age.

Uses of Trigaan Injection 30 ml

Treatment of Irritable bowel syndrome (IBS)

Medicinal Benefits

Trigaan Injection 30 ml contains ‘Dicyclomine,’ also known as Dicycloverine. Dicyclomine is an ‘anticholinergic/anti-muscarinic agent’ with antispasmodic activity. Trigaan Injection 30 ml effectively treats irritable bowel syndrome (IBS). It works by blocking the activity of acetylcholine by binding to muscarinic receptors on smooth muscle. This process helps relax the smooth muscles, inhibits natural gut movements, decreases gastric acid secretion, and controls excessive gastrointestinal secretions. Thus it prevents spasms in the muscles of the stomach and intestines. Trigaan Injection 30 ml is also used to relieve stomach cramps, bloating, and pain in the stomach and intestine.

Directions for Use

It will be administered by a healthcare professional; do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Trigaan Injection 30 ml

  • Dizziness
  • Drowsiness
  • Light-headedness
  • Weakness
  • Nervousness
  • Blurred vision
  • Dry mouth
  • Nausea
  • Constipation
  • Trouble sleeping 

Drug Warnings

Let your doctor know if you are sensitive to Trigaan Injection 30 ml or its inactive components. Trigaan Injection 30 ml should be used with caution and only under doctor’s supervision if you have stomach/intestinal problems like slow gut, bowel blockage, acid reflux, ulcerative colitis (inflammation of the colon), and diarrhoea due to intestine surgeries like ileostomy and colostomy. Also, inform your doctor if you have any liver or kidney diseases, urinary retention problems (enlarged prostate), glaucoma, high blood pressure, heart diseases (irregular heart rhythm, coronary artery disease, heart failure), nervous system disorders, and myasthenia gravis (muscle weakness) before using Trigaan Injection 30 ml. This medicine may cause blurry vision and sleepiness affecting your mental focus; hence do not drive or operate machinery until you feel better. Tell your doctor if you are pregnant, planning pregnancy, or a nursing mother before being treated with Trigaan Injection 30 ml.

Drug Interactions

Drug-Drug Interaction: Trigaan Injection 30 ml may interact with other anticholinergics (amantadine), heart-related drugs (quinidine), opiate pain medicines (meperidine), anti-emetics (metoclopramide), common cold medicines (diphenhydramine), muscle relaxants (cyclobenzaprine), high blood pressure medications (metoprolol), anti-glaucoma agents, and antacids.

Drug-Food Interaction: Avoid fatty foods, alcohol, caffeine and other triggering foods that can worsen your IBS.

Drug-Disease Interaction: Brief your doctor if you have a medical history of stomach/intestinal problems, liver or kidney diseases, glaucoma, high blood pressure, heart diseases, urinary retention problems, nervous system disorders, and myasthenia gravis before using Trigaan Injection 30 ml.

Drug-Drug Interactions Checker List

  • AMANTADINE
  • QUINIDINE
  • MEPERIDINE
  • METOCLOPRAMIDE
  • DIPHENHYDRAMINE
  • CYCLOBENZAPRINE
  • METOPROLOL

Habit Forming

No

Diet & Lifestyle Advise

  • Avoid or limit the intake of alcohol and caffeine.
  • Manage stress, eat healthily, drink plenty of water, exercise regularly, and get plenty of sleep.
  • Limit taking high-fibre foods and drinks containing chocolate, milk, alcohol, caffeine, fructose, sorbitol, carbonated drinks, fried, and fatty foods. 
  • Do not have large meals at a time; instead, try having small and simpler meals at regular intervals, including fresh fruits and vegetables.
  • Practice yoga and recreation techniques to manage your emotional stress.
  • If you are lactose intolerant, avoid using dairy products since they can worsen your IBS.
  • If you cannot take dairy products, it is advised to include other calcium-rich foods like leafy greens, beans, nuts, and seeds.
  • Drink plenty of fluids and dress lightly to prevent heatstroke and dehydration.
  • Avoid overly sweating activities like hard exercises and using hot tubs.

Disease/Condition Glossary

Irritable Bowel Syndrome (IBS): IBS is also known as IBS colitis, mucous colitis, spastic colon, nervous colon, and spastic bowel. It is an inflammatory bowel disease that affects the large intestine. Symptoms of an IBS include abdominal pain, bloating, diarrhoea, mucus in stools, wind, constipation, tiredness, anxiety, depression, heartburn, indigestion, and headaches. IBS can be controlled by managing diet, excluding certain intolerant foods, lifestyle and stress. It is commonly found in people in their late teens to early 40s. 

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Alcohol

Caution

Avoid consuming alcohol while being treated with Trigaan Injection 30 ml as it may worsen your condition. Please consult your doctor for more information.

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Pregnancy

Caution

If you are pregnant, inform your doctor before taking Trigaan Injection 30 ml. Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Breast Feeding

Unsafe

It is not recommended to use Trigaan Injection 30 ml during breastfeeding. Trigaan Injection 30 ml can pass into breast milk and cause undesirable effects in infants.

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Driving

Unsafe

Trigaan Injection 30 ml may cause side effects like dizziness, drowsiness, and blurry vision, which could affect your ability to focus. Please do not drive or operate machines until you feel better.

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Liver

Caution

Let your doctor know if you have any history of liver diseases or hepatic impairment. Your doctor will adjust the dose or prescribe a suitable alternative based on your condition.

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Kidney

Caution

Let your doctor know if you have any history of kidney diseases. Your doctor will adjust the dose or prescribe a suitable alternative based on your condition.

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Children

Caution

Trigaan Injection 30 ml is not recommended for children younger than six months. Your doctor will decide the dose and duration based on your child’s age and medical condition.

Country of origin

India

Manufacturer/Marketer address

Old No. 52, New No. 131, Ground Floor, Singanna Chetty Street Anna Salai, Chintadripet, Chennai - 600 002
Other Info - TRI2141

Author Details

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FAQs

Trigaan Injection 30 ml is used to treat functional bowel or irritable bowel syndrome (IBS). It reduces spasms (sudden involuntary contraction) of the muscles in the stomach and intestines.
Trigaan Injection 30 ml consists of Dicyclomine, an anticholinergic agent that treats irritable bowel syndrome. It works by relaxing the muscles and inhibiting natural gut movements, thus relieving muscle spasms and cramps in the stomach and intestine, abdominal pain, constipation and other gastrointestinal discomforts.
Trigaan Injection 30 ml should be used with caution if you have any liver, kidney or heart diseases, stomach and intestinal problems, muscle weakness (myasthenia gravis), nervous system disorders, glaucoma, urinary retention, and glaucoma (damage to the optic (eye) nerve).
Drug use can cause heat prostration (fever and heat stroke because of decreased sweating); it should be stopped, and supportive measures should be implemented.
Antacids may lower the absorption of Trigaan Injection 30 ml and reduce its efficacy. It is advised to take antacid and Trigaan Injection 30 ml with a time gap of two hours. Please seek medical advice for more information.
If you suffer from IBS, limit taking milk products, high-fibre foods, foods and drinks that contain chocolate, alcohol, caffeine, fructose, or sorbitol, carbonated drinks, and fried and fatty foods. Do not have large meals; instead, try having small and simpler meals at regular intervals, including fresh fruits and vegetables.

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