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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 9, 2024 | 12:40 PM IST
Tretiva-25 Capsule is used to treat a severe form of acne known as nodular acne that cannot be cleared by any other treatments, including antibiotics. It contains Isotretinoin, a form of vitamin A, which works by reducing sebum (skin's natural oil) production on the skin's surface by decreasing the activity and size of sebaceous glands. Thereby, unblocks pores and kills acne-causing bacteria. Some people may experience chapped lips, dryness of skin, eyes, nose, or lips. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Composition :

ISOTRETINOIN-25MG

Manufacturer/Marketer :

Intas Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

Jan-27

About Tretiva-25 Capsule

Tretiva-25 Capsule belongs to a class of drugs called retinoids (a synthetic form of vitamin A) primarily used to treat a severe form of acne known as nodular acne that cannot be cleared by any other treatments, including antibiotics. Nodular acne is severe acne that occurs due to excessive production of oil in the skin cells, causing swollen, red and tender lumps in the skin. Acne nodules are larger in size than typical pimples. 

Tretiva-25 Capsule contains 'isotretinoin', a form of vitamin A that works by reducing sebum (skin's natural oil) production on the skin's surface by decreasing the activity and size of sebaceous glands. Thereby unblocks pores and kills acne-causing bacteria.

Take Tretiva-25 Capsule as prescribed. Your doctor will advise you on how often you need to take Tretiva-25 Capsule based on your medical condition. Some people may experience chapped lips, dryness of skin, eyes, nose, or lips. Most of these side effects of Tretiva-25 Capsule do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are known to be allergic to Tretiva-25 Capsule or any other medicines, please tell your doctor. Do not take Tretiva-25 Capsule if you are pregnant or breastfeeding as it may cause adverse effects on the baby. If you have depression or any suicidal thoughts while taking Tretiva-25 Capsule or after stopping treatment with Tretiva-25 Capsule , please consult a doctor. Avoid sun exposure while using Tretiva-25 Capsule as it may make the skin more sensitive to sunlight and cause sunburn. Wear protective clothing and use sunscreen while going out to protect your skin from sunburn.

Uses of Tretiva-25 Capsule

Treatment of Nodular acne

Medicinal Benefits

Tretiva-25 Capsule is a synthetic form of vitamin A used to treat a severe form of acne. Tretiva-25 Capsule reduces sebum (skin's natural oil) production on the skin's surface by decreasing the activity and size of sebaceous glands. Thereby unblocking pores and killing acne-causing bacteria. Also, Tretiva-25 Capsule reduces swelling in the skin.

Side Effects of Tretiva-25 Capsule

  • Chapped lips

  • Dryness of skin, eyes, nose or lips

Directions for Use

Take Tretiva-25 Capsule with food or as advised by the doctor. Swallow it as a whole with a glass of water. Do not break, crush or chew it.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Do not take Tretiva-25 Capsule if you are pregnant or breastfeeding as it may cause adverse effects in the baby. If you have depression or any suicidal thoughts while taking Tretiva-25 Capsule or after stopping treatment with Tretiva-25 Capsule , please consult a doctor. Avoid sun exposure while using Tretiva-25 Capsule as it may make the skin more sensitive to sunlight and cause sunburn. Wear protective clothing and use sunscreen while going out to protect your skin from sunburn. Do not undergo any cosmetic procedures while taking Tretiva-25 Capsule and for a minimum of 6 months after stopping treatment with Tretiva-25 Capsule as it may increase the risk of scarring. Inform your doctor if you have asthma, diabetes, hypervitaminosis A (high levels of vitamin A), liver or heart problems, weak bones, osteoporosis (bone loss), anorexia nervosa (an eating disorder where people eat too little), any mental problems such as psychosis (loss of contact with reality) or depression before taking Tretiva-25 Capsule .

Therapeutic Class

RETINOIDS

Drug-Drug Interactions

verifiedApollotooltip
IsotretinoinDemeclocycline
Critical
IsotretinoinOxytetracycline
Critical

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Diet & Lifestyle Advise

  • Regular exercise can improve your mood and self-esteem though it doesn't clear acne. Take a shower immediately after finishing exercise as sweat may irritate acne.

  • Avoid sun exposure while using Tretiva-25 Capsule as it may make the skin more sensitive to sunlight and cause sunburn. Wear protective clothing and use sunscreen while going out to protect your skin from sunburn.

  • Do regular hair wash and avoid contact of hair with the face.

  • Remove the make-up completely before going to bed.

Habit Forming

No

What if I have taken an overdose of Tretiva-25 Capsule

Do not take more than the prescribed dose of Tretiva-25 Capsule as it may cause overdose. The symptoms of overdose include vomiting, dizziness, headache, stomach pain, loss of balance or coordination, warmth or tingling in your face and swollen or cracked lips. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.
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Alcohol

Unsafe

Avoid consumption of alcohol with Tretiva-25 Capsule as it may increase the risk of liver damage and cause a rise in cholesterol levels.

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Pregnancy

Unsafe

Tretiva-25 Capsule is a Category X pregnancy drug and is considered unsafe for pregnant women as it may cause severe birth defects. Please consult a doctor if you are pregnant or planning for pregnancy.

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Breast Feeding

Unsafe

Tretiva-25 Capsule may be excreted in breast milk and cause adverse effects in the baby. Please consult a doctor before using Tretiva-25 Capsule while breastfeeding.

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Driving

Caution

Tretiva-25 Capsule may cause reduced night vision in some patients. Therefore, drive only if you alert after taking Tretiva-25 Capsule .

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Liver

Unsafe

Tretiva-25 Capsule is usually not recommended for patients with impaired liver function. If you have any concerns regarding the use of Tretiva-25 Capsule in patients with liver problems, please consult a doctor.

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Kidney

Caution

If you have any concerns regarding the use of Tretiva-25 Capsule in patients with kidney problems, please consult a doctor.

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Children

Unsafe

Tretiva-25 Capsule is not recommended for children below 12 years of age.

Country of origin

India

Manufacturer/Marketer address

Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.
Other Info - TRE0074

Author Details

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FAQs

Tretiva-25 Capsule is used to treat a severe form of acne known as nodular acne that cannot be cleared by any other treatments, including antibiotics.
Tretiva-25 Capsule may cause decreased night vision temporarily or permanently in some patients. It is not necessary for everyone taking Tretiva-25 Capsule to experience this side effect. Avoid driving after taking Tretiva-25 Capsule if you are unable to see in the dark and consult a doctor if you notice any changes in vision or have painful or persistent dry eyes.
Tretiva-25 Capsule may increase the skin sensitivity to sunlight. Therefore, avoid or limit exposure to sunlight and sunlamps. You are advised to use sunscreen and wear protective clothing while going out to prevent sunburn.
No, you are not recommended to undergo any cosmetic procedures to smoothen your skin including waxing, laser procedures or dermabrasion (an exfoliating technique to remove outer layers of skin with a rotating instrument) while taking Tretiva-25 Capsule and for minimum 6 months after stopping treatment with Tretiva-25 Capsule as it may increase the risk of scarring.
You are not recommended to take vitamin A supplements with Tretiva-25 Capsule as it may cause hypervitaminosis A (excessive levels of vitamin A in the body) leading to an increased risk of adverse effects. However, please consult a doctor before taking other medicines or supplements with Tretiva-25 Capsule .
No, Tretiva-25 Capsule is not recommended for use during pregnancy as it may cause severe birth defects. Also, it is advised to use effective contraceptive measures before, while taking Tretiva-25 Capsule and after 1 month of stopping treatment with Tretiva-25 Capsule . However, please inform your doctor if you are pregnant, planning for pregnancy or breastfeeding before taking Tretiva-25 Capsule .
Tretiva-25 Capsule is safe to use if prescribed by the doctor. Use Tretiva-25 Capsule exactly as advised by the doctor as it is associated with adverse effects.
Tretiva-25 Capsule is not a steroid. It is a retinoid used to treat severe nodular acne.
Pregnancy tests, lipid profile tests, liver function tests, blood glucose tests, and creatine phosphokinase (CPK) tests are recommended tests during Tretiva-25 Capsule treatment.
In most cases the effect of Tretiva-25 Capsule is permanent. Isotretinoin is clinically effective anti-acne therapy that shows significant improvement in many patients.
Tretiva-25 Capsule does not cause cancer. In fact, isotretinoin slows the growth of cancer cells by activating protein receptors in cells, including cancer cells.
Long-term use of Tretiva-25 Capsule , even in low doses, has not been studied and is not recommended. Hence, long-term side effects of Tretiva-25 Capsule have not been established.
Tretiva-25 Capsule is not known to affect male fertility.
Tretiva-25 Capsule might elevate liver enzymes. Therefore, regular liver function tests are advised.
Side effects of Tretiva-25 Capsule include chapped lips and dry skin, eyes, nose, or lips. Most of these side effects may not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

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