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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Nov 23, 2024 | 4:48 PM IST
Toxocare Tablet is an antibiotic used to treat cryptosporidiosis (a diarrheal disease caused by microscopic parasites, cryptosporidium), susceptible infections, and soft tissue infections. It is also used to treat a parasitic infection known as toxoplasmosis in pregnant women. It helps to lower the risk of transmission of toxoplasma infection from the mother to the unborn child. It contains Spiramycin, which stops bacterial and parasitic reproduction.
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Composition

SPIRAMYCIN-3MIU

Manufacturer/Marketer

Corona Remedies Pvt Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Toxocare Tablet

Toxocare Tablet belongs to a group of medicines known as macrolide antibiotics primarily used to treat cryptosporidiosis (a diarrheal disease caused by microscopic parasites, cryptosporidium), susceptible infections, and soft tissue infections. It is also used to treat a parasitic infection known as toxoplasmosis in pregnant women. It helps to lower the risk of transmission of toxoplasma infection from the mother to the unborn child. A bacterial infection is a condition in which bacteria grows in the body and causes infection. It can target any body part and multiple very quickly. Toxoplasmosis infection can cause complications such as miscarriage, stillbirth, and damage to a baby’s brain and other organs, particularly the eyes, at birth or early childhood, or even as adults with a weak immune system.

Toxocare Tablet contains ‘Spiramycin,’ an antibiotic that treats bacterial infections of the abdomen, bone, skin, heart, and soft tissues. It may also be used to reduce the risk of a serious parasite infection (toxoplasmosis) spreading to an unborn baby during pregnancy. Toxocare Tablet works by inhibiting bacterial protein synthesis, which inhibits bacterial growth. It shows a bacteriostatic effect, which stops bacterial and parasitic reproduction but doesn't kill them. 

Take Toxocare Tablet as prescribed by your doctor. You are advised to take Toxocare Tablet for the duration as prescribed, depending on your medical condition. Toxocare Tablet causes side effects in some people. Common side effects of Toxocare Tablet include stomach pain, nausea, vomiting, and diarrhea. Most of these side effects of Toxocare Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are known to be allergic to Toxocare Tablet or any other medicines, please tell your doctor. Do not use Toxocare Tablet while having vaccinations with live bacterial vaccines (typhoid vaccine) since Toxocare Tablet may affect the vaccine's activity. Toxocare Tablet should be used only with a doctor's advice during pregnancy and breastfeeding. Do not give this medicine to your child without medical advice. Tell your doctor if you have liver problems, muscle problems (myasthenia gravis), heart rhythm disorder (arrhythmia), porphyria (rare genetic blood disorder), or electrolyte imbalance (low potassium or magnesium level).

Uses of Toxocare Tablet

Treatment of Bacterial infections, Toxoplasmosis during pregnancy.

Medicinal Benefits

Toxocare Tablet contains ‘Spiramycin’ as an antibiotic that treats bacterial infections like various infections of the abdomen, bone, skin, heart and soft tissues. It may also reduce the risk of a serious parasite infection (toxoplasmosis) spreading to an unborn baby during pregnancy. Toxocare Tablet works by inhibiting bacterial protein synthesis, which inhibits bacterial growth. It shows a bacteriostatic effect, which stops bacterial reproduction but doesn't kill them. Toxocare Tablet effectively treats infections caused by gram-positive and aerobic (living with air) bacteria, including susceptible strains of Staphylococcus aureus, Streptococcus pneumonia, N. gonorrhoea,  gram-negative bacteria, and cryptosporidium spices. Toxocare Tablet treats serious infections caused by susceptible aerobic bacteria in the abdomen, gastrointestinal tract, lower respiratory tract, skin, and in genitourinary area. It will not work for viral infections (such as the common cold or flu).

Directions for Use

Swallow the capsule as a whole with a glass of water with or without food. Do not chew, crush, or break it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Toxocare Tablet

  • Nausea
  • Vomiting
  • Abdominal pain
  • Diarrhea
  • Allergy
  • Abnormal liver function
  • Abnormal heart rate
  • Hypotension

Drug Warnings

Do not use Toxocare Tablet if you are allergic to Toxocare Tablet or its components. Tell your doctor if you have liver problems, muscle problems (myasthenia gravis), heart rhythm disorder (arrhythmia), porphyria (rare inherited blood disorders), or electrolyte imbalance (low potassium or magnesium level). Regular monitoring of liver function tests may be required while using Toxocare Tablet . In rare cases, the use of Toxocare Tablet can cause diarrhoea, so in case you have watery or bloody diarrhoea, stop taking Toxocare Tablet and call your doctor. However, do not take any anti-diarrheal medicine until your doctor tells you.  Toxocare Tablet is safe to use during pregnancy. However, please consult your doctor if you are pregnant, planning for pregnancy, or breastfeeding before using Toxocare Tablet . It should be taken by the children only if the doctor has prescribed it. In some cases, Toxocare Tablet may cause a condition that affects the heart rhythm (QT prolongation). QT prolongation can rarely cause fast/irregular heartbeat and other symptoms (such as severe dizziness and fainting) that need medical attention immediately. Elderly adults may be more sensitive to the side effects of Toxocare Tablet , especially QT prolongation. Toxocare Tablet may cause live bacterial vaccines (such as typhoid vaccine) to not work as well. Do not have any immunizations/vaccinations while using this medication unless your doctor tells you to. Do not skip the doses and finish the full course of treatment even if you feel better. Stopping the Toxocare Tablet too early may lead to the infection returning or worsening.

Drug Interactions

Drug-Drug Interaction: Toxocare Tablet have interactions with ergot alkaloids (ergotamine, dihydroergotamine), drugs used to treat abnormal heart rhythm (amiodarone, dofetilide, pimozide, procainamide, quinidine), macrolide antibiotics (erythromycin).

Drug-Food Interaction: No relevant drug-food interaction was found with Toxocare Tablet . As a precautionary measure, the consumption of alcoholic beverages should be avoided as it may lead to drowsiness and dizziness.

Drug-Disease Interaction: Toxocare Tablet should not be given to people with liver problems, muscle problems (myasthenia gravis), heart rhythm disorder (arrhythmia), electrolyte imbalance (low potassium or magnesium level), colitis (inflammation of the intestine), and porphyria (rare genetic blood disorder).

Drug-Drug Interactions Checker List

  • ERGOTAMINE
  • DIHYDROERGOTAMINE
  • AMIDODARONE
  • DOFETILIDE
  • PIMOZIDE
  • PROCAINAMIDE
  • QUINIDINE
  • ERYTHROMYCIN

Habit Forming

No

Diet & Lifestyle Advise

  • Probiotics should be taken after taking a full course of Toxocare Tablet in order to restore some of the healthy bacteria in the intestines that may have been killed. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhoea. Certain fermented foods like yoghurt, cheese, sauerkraut, kombucha, and kimchi can help to restore the good bacteria of the intestine. 

  • Include more fibre-enriched food in your diet, as it can be easily digested by gut bacteria, which helps stimulate their growth. Thus, fibre foods may help restore healthy gut bacteria after antibiotics. Whole grains like whole-grain bread and brown rice should be included in your diet. 

  • Avoid taking too much calcium, iron-enriched foods, and drinks as it might affect the working of Toxocare Tablet . 

  • Avoid intake of alcoholic beverages with Toxocare Tablet as it can make you dehydrated and affect your sleep. This can make it harder for your body to aid the Toxocare Tablet in fighting off infections.

Special Advise

  • Liver function monitoring (liver function tests) is recommended in patients with severe liver disease.

  • Toxocare Tablet may cause Clostridium difficile-associated diarrhea (CDAD); hence it is advised to undergo regular gastrointestinal screening.

Disease/Condition Glossary

A bacterial infection:  It is a condition in which harmful bacteria enter, multiply, and infect our body. It can target any body part and multiple very quickly. When you get infected with bacteria, you can experience generalized symptoms like fevers, chills, and fatigue. Bacteria are of various forms comprising, commonly spherical, rod, and spiral-shaped. Bacterial infections vary from minor illnesses like sore throat and ear infections to severe brain infections like meningitis and encephalitis. Few harmful bacteria that cause infections include Streptococcus, Staphylococcus, and E. coli. Anyone can become infected with a bacterial infection. But, people with weak immune systems or taking immunosuppressive medicine can make you more prone to bacterial infection.

Toxoplasmosis: is an infection caused by parasites toxoplasma gondii found in contaminated food and cat feces. It can cause serious complications for pregnant women, such as miscarriage, stillbirths, and damage to the baby’s brain and other organs, particularly the eyes, at birth or early childhood, and people with weakened immune systems. Symptoms include muscle pain, fever, headache, etc.

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Alcohol

Caution

Avoid taking alcohol while using Toxocare Tablet since it may worsen the side effects.

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Pregnancy

Caution

Toxocare Tablet is a pregnancy category C drug. If you are pregnant, think you may be pregnant, or planning pregnancy, consult your doctor before taking Toxocare Tablet . Your doctor may prescribe this medicine only if the benefits outweigh the risks.

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Breast Feeding

Caution

Toxocare Tablet may be excreted into breast milk and may harm your infant. Please consult your doctor before taking Toxocare Tablet if you are breastfeeding.

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Driving

Caution

You may experience dizziness by taking Toxocare Tablet . In such cases, do not drive or operate machinery until you feel better.

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Liver

Caution

Toxocare Tablet is used with caution in patients with liver disease. If you have liver problems, consult your doctor before taking Toxocare Tablet . Your doctor may adjust the dose or prescribe a suitable alternative based on your condition.

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Kidney

Caution

If you have kidney problems, consult your doctor before taking Toxocare Tablet . Your doctor may adjust the dose or prescribe a suitable alternative based on your condition.

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Children

Caution

Your doctor will prescribe Toxocare Tablet depending on your child's age and body weight.

Country of origin

India

Manufacturer/Marketer address

Corona House, Block C, Mondeal Business Park, Near Gurudwara,, S. G. Highway, Thaltej, Thaltej, Ahmedabad, Gujarat 380059.
Other Info - TOX0015

Author Details

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FAQs

Toxocare Tablet is used to treat cryptosporidiosis (a diarrheal disease caused by microscopic parasites, cryptosporidium), susceptible infections, and soft tissue infections. It is also used to treat a parasitic infection known as toxoplasmosis in pregnant women. It helps to lower the risk of transmission of toxoplasma infection from the mother to the unborn child.
Toxocare Tablet contains Spiramycin' which works by preventing the synthesis of essential proteins required by bacteria and parasites to carry out vital functions. Thus, it stops the bacteria or parasite's growth and prevents the infection from spreading.
You are not recommended to use Toxocare Tablet with amiodarone (a medicine used to treat abnormal heart rhythm) simultaneously as it may affect the heart rhythm (QT prolongation). QT prolongation can rarely cause serious and sometimes fatal fast/irregular heartbeat and other symptoms (such as severe dizziness and fainting) that need immediate medical attention. However, please consult a doctor before using Toxocare Tablet with any other medicines.
Toxocare Tablet can affect live vaccines like typhoid vaccine and decrease their effectiveness. Please consult a doctor before you start Toxocare Tablet if you are undergoing any vaccinations.
Do not use anti diarrhoeal until the doctor has prescribed you. You can drink plenty of fluids (electrolytes) to avoid dehydration. Besides this, you can also take prebiotics or probiotics to manage diarrhoea, as it may help increase the number of good bacteria in the intestine, which aids in digestion.
In some cases, people using Toxocare Tablet may have a fungal infection called thrush after taking its full course. It happens because antibiotics also kill the harmless bacteria that protect against thrush.
No. You should complete the full course of Toxocare Tablet as your doctor prescribes. Take Toxocare Tablet at the right dose, times, and for the right number of days.
The side effects of Toxocare Tablet include nausea, vomiting, dizziness, diarrhoea, stomach pain, abnormal heart rate and hypotension (low blood pressure). If these side effects persist or worsen, please consult your doctor.
Toxocare Tablet generally starts working immediately after taking it. However, to kill all the harmful bacteria and make you feel better it may take few days.
If you don't feel better after completing the full course of treatment with Toxocare Tablet , inform your doctor. Also, let your doctor know if your symptoms are worsening while taking Toxocare Tablet .
There is no strong evidence suggesting that Toxocare Tablet causes infertility in either males or females. However, if you have any concerns, please discuss with your doctor.

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