Totnist-0.4mg MR Tablet belongs to the category of medicine known as alpha-blocker, used primarily for treating benign prostatic hyperplasia - BPH (enlarged prostate), and urinary bladder outlet obstruction. Totnist-0.4mg MR Tablet is for use by men only and not indicated for use by women. Totnist-0.4mg MR Tablet does not cure prostate cancer. Benign prostatic hyperplasia (enlarged prostate gland) is a non-cancerous growth of the prostate gland caused by the overproduction of a hormone called ‘dihydrotestosterone’ in men. As the gland enlarges, it can lead to urinary problems, such as difficulty passing urine and frequent urination. Totnist-0.4mg MR Tablet helps in getting relief from these symptoms.

Totnist-0.4mg MR Tablet contains Tamsulosin (alpha-blocker), which primarily treats the enlarged prostate gland, leading to urinary problems (like difficulty in passing urine and a frequent urination urge). Totnist-0.4mg MR Tablet  relaxes the prostate gland’s muscles and urinary bladder neck at the obstruction site, resulting in improved urine flow and reduced BPH symptoms.

Totnist-0.4mg MR Tablet should be taken approximately 30 minutes following the same meal every day. The most common side effects of Totnist-0.4mg MR Tablet are low blood pressure (hypotension), dizziness, drowsiness, reduced sex drive (libido), inability to get an erection (impotence), tenderness or enlargement of your breasts (in men), sleeplessness, runny nose, or ejaculatory problems. These side effects may disappear when you continue to take Totnist-0.4mg MR Tablet . Although, if these side effects persist, contact the doctor.

Women or children should not take Totnist-0.4mg MR Tablet . Please inform your doctor before starting $ if  you have low blood pressure, liver/kidney disease, or a history of heart problems. You are also advised to wear a condom while having sexual intercourse, especially when your partner is pregnant, as Totnist-0.4mg MR Tablet is known to pass in semen. Do not donate blood while taking Totnist-0.4mg MR Tablet . You can donate blood six months after you have taken the last dose of Totnist-0.4mg MR Tablet . Patients taking Totnist-0.4mg MR Tablet should be cautioned about driving, operating machinery or performing hazardous tasks as it can cause drowsiness or dizziness. In rare cases, problems of penis erection, ejaculation and pain in the penis. So if these symptoms are for a longer time, immediately contact your doctor.

Totnist-0.4mg MR Tablet contains tamsulosin (alpha-blocker), which primarily treats the enlarged prostate gland. This decreases urinary problems, like difficulty in passing urine and a frequent urination urge. Totnist-0.4mg MR Tablet makes it easy to pass urine by relaxing the gland muscles. Effectively, it improves the symptoms of BPH like urine flow, hesitancy, and incomplete bladder emptying.

• Low blood pressure (hypotension)

• Dizziness

• Drowsiness

• Reduced sex drive (libido)

• Inability to get an erection (impotence)

• Tenderness or enlargement of your breasts (in men)

• Sleeplessness

• Runny nose

• Ejaculatory problems

Totnist-0.4mg MR Tablet should be taken with caution in people with liver or kidney disease, low blood pressure, a history of prostate cancer, or allergic to tamsulosin. Totnist-0.4mg MR Tablet should be used 30 minutes after a meal for better results. Inform your doctor if you have had a history of heart disease or planning to undergo cataract surgery. During sexual intercourse with your partner, use a condom as Totnist-0.4mg MR Tablet passes in semen and can affect pregnant women and the foetus (unborn child). So, you should contact your doctor for advice. Do not donate blood while taking Totnist-0.4mg MR Tablet . You can donate blood six months after you have taken the last dose of Totnist-0.4mg MR Tablet . Patients taking Totnist-0.4mg MR Tablet should be cautioned about driving, operating machinery, or performing hazardous tasks as it can cause drowsiness or dizziness. In rare cases, problems of penis erection, ejaculation, and pain in the penis can occur. So if these symptoms are for a longer time, immediately contact your doctor.

Drug-Drug Interactions: Totnist-0.4mg MR Tablet is known to contra-indicate with antibiotics (clarithromycin, erythromycin, doxycycline), antidepressants (fluoxetine, paroxetine), antifungals (itraconazole and ketoconazole), blood pressure-lowering pills (atenolol, metoprolol, prazosin, terazosin), pain killers (diclofenac, ibuprofen, indomethacin).

Drug-Food Interactions: Totnist-0.4mg MR Tablet is known to interact when taken along with alcohol. Also, keep your doctor informed about all the OTC medicines you are using while taking Totnist-0.4mg MR Tablet .

Drug-Disease Interactions: Totnist-0.4mg MR Tablet may interact if you have glaucoma, liver/kidney disease, hypotension (low blood pressure).

• ERYTHROMYCIN
• DOXYCYCLINE
• FLUOXETINE
• DICLOFENAC
• IBUPROFEN
• PRAZOSIN
• ATENOLOL
• CLARITHROMYCIN
• PAROXETINE
• ITRACONAZOLE
• KETOCONAZOLE
• METOPROLOL
• TERAZOSIN
• INDOMETHACIN

• Avoid drinking less alcohol, caffeine, and fizzy drink. Limit intake of artificial sweeteners.
• Maintain a healthy lifestyle and exercise regularly, so you do not feel heavy in the abdomen.
• Also, drink less water in the evening and before sleeping to have a sound sleep and do not wake up frequently for urination.
• Any medication that may worsen urinary symptoms (for cold and cough) should be avoided.

• Totnist-0.4mg MR Tablet is not intended for use as an antihypertensive (blood pressure lowering) drug.

• Don't stand suddenly from a lying or resting position which may increase the risk of falls.

Benign prostatic hyperplasia (BPH): The enlargement of the prostate gland is benign prostatic hyperplasia (BPH). It is a non-cancerous growth of the prostate gland caused due to overproduction of dihydrotestosterone hormone in men. After age 50, most men develop an enlarged prostate gland putting pressure on the urinary bladder. It leads to restricted or obstructed urine flow, an urge to urinate frequently (especially at night), and a feeling of not emptying the urinary bladder.