TORISEL 25MG INJECTION

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TORISEL 25MG INJECTION

TORISEL 25MG INJECTION, Pack of 1 INJECTION

Written By Santoshini Reddy G , M Pharmacy

Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

TORISEL 25MG INJECTION is used to treat advanced renal cell carcinoma (a type of cancer that begins in the kidney). It contains Temsirolimus, which works by blocking the action of abnormal proteins needed for cancer cells to multiply. This helps slow the growth of tumours, thus helping treat kidney cancer. Sometimes, TORISEL 25MG INJECTION may cause side effects such as diarrhoea, nausea, vomiting, constipation, headache, fever, and decreased appetite.

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Composition :

TEMSIROLIMUS-25MG

Manufacturer/Marketer :

Pfizer Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About TORISEL 25MG INJECTION

TORISEL 25MG INJECTION contains Temsirolimus, which works by blocking the action of abnormal proteins needed for cancer cells to multiply. This helps slow the growth of tumours. Thereby, it helps treat kidney cancer.

In some cases, TORISEL 25MG INJECTION may cause side effects such as diarrhoea, nausea, vomiting, constipation, headache, fever, and decreased appetite. Most of these side effects may not require medical attention and resolve over time. Do not be reluctant to talk with your doctor if any of these side effects persist or worsen.

Consult the doctor if you are pregnant or breastfeeding. TORISEL 25MG INJECTION is not recommended for children below 18 years as the effectiveness has not been established. Keep your doctor informed about your health condition and medications to rule out any side effects/interactions.

Uses of TORISEL 25MG INJECTION

Treatment of Renal cell cancer (Kidney cancer)

Directions for Use

TORISEL 25MG INJECTION will be administered by a healthcare professional who is trained and experienced in the administration of anticancer medicine; do not self-administer.

Medicinal Benefits

TORISEL 25MG INJECTION belongs to the group of anti-cancer medicines called kinase inhibitors used to treat advanced renal cell carcinoma (a type of cancer that begins in the kidney). It may also be used for previously treated mantle cell lymphoma (a type of cancer affecting the lymph nodes). TORISEL 25MG INJECTION contains Temsirolimus, a selective inhibitor of the enzyme mTOR (mammalian target of rapamycin) that blocks tumour cell growth and division. Thereby, it helps treat kidney cancer.

How TORISEL 25MG INJECTION Works

Storage

Store in a cool and dry place away from sunlight

Side effects of Torisel 25mg Injection

Weakness

Rest well; get enough sleep.
Eat a balanced diet and drink enough water.
Manage stress with yoga and meditation.
Limit alcohol and caffeine.
Physical activities like walking or jogging might help boost energy and make you feel less tired.

High Body Temperature

Here's a comprehensive approach to managing medication-triggered fever:

Inform your doctor immediately if you experience a fever after starting a new medication.
Your doctor may adjust your medication regimen or dosage as needed to minimize fever symptoms.
Monitor your body temperature to monitor fever progression.
Drink plenty of fluids, such as water or electrolyte-rich beverages, to help your body regulate temperature.
Get plenty of rest and engage in relaxation techniques, such as deep breathing or meditation, to help manage fever symptoms.
Under the guidance of your doctor, consider taking medication, such as acetaminophen or ibuprofen, to help reduce fever.
If your fever is extremely high (over 103°F), or if you experience severe symptoms such as confusion, seizures, or difficulty breathing, seek immediate medical attention.

Weight Loss

Weight loss without physical activity needs immediate medical attention.
Get a physical examination and blood tests done to identify factors causing weight loss that could be related to metabolism and thyroid function.
Avoid smoking and alcohol intake as it can alter your liver condition and increase your weight loss.
Practice meditation and yoga to avoid anxiety, which can be one of the leading causes of weight loss.
Talk to your dietician and consume food which can maintain ideal weight.

Stomach Pain

Drink water or other clear fluids.
To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
Include bland foods like rice, toast, crackers, and rice in your diet.
Avoid lying down immediately after eating as it may cause indigestion or heartburn.
Avoid acidic and spicy food as it may cause indigestion.

Constipation

Here are the steps to cope with constipation as a side effect of medication:

Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.

Sore Throat

Drink warm fluids such as warm water with honey, broth, soup or herbal tea to soothe sore throat.
Gargle with warm salt water.
Suck on lozenges to increase the production of saliva and soothe your throat.
Use a humidifier to soothe sore throat as it adds moisture to the air and makes breathing easier.

Joint Pain

Here are the steps to manage Joint Pain caused by medication usage:

Please inform your doctor about joint pain symptoms, as they may adjust your medication regimen or prescribe additional medications to manage symptoms.
Your doctor may prescribe common pain relievers if necessary to treat joint discomfort.
Maintaining a healthy lifestyle is key to relieving joint discomfort. Regular exercise, such as low-impact sports like walking, cycling, or swimming, should be combined with a well-balanced diet. Aim for 7-8 hours of sleep per night to assist your body in repairing and rebuilding tissue.
Applying heat or cold packs to the affected joint can help reduce pain and inflammation.
Please track when joint pain occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
If your joint pain is severe or prolonged, consult a doctor to rule out any underlying disorders that may require treatment.

What if I have taken an overdose of TORISEL 25MG INJECTION

As TORISEL 25MG INJECTION is a parenteral formulation administered by experienced medical staff, the chance of overdose may be less. However, if you think there has been an overdose or experiencing any adverse events, get medical care right away. Overdose of TORISEL 25MG INJECTION may cause cough, difficulty thinking clearly, fever, seizure, hallucinating (seeing things or hearing voices that do not exist), shortness of breath, new or worsening abdominal pain, panting or fast breathing, red blood in stools, diarrhea, leg pain, swelling, tenderness, redness, and understanding reality, or using good judgment.

Drug Warnings

Do not use TORISEL 25MG INJECTION if you are allergic to any of its components if you are allergic to sirolimus (immunosuppressant), or if you have mantle cell lymphoma or liver problems. Inform the doctor if you are allergic to or cannot use anti-histamines if you have/had a tumour in the brain or spinal cord, bruising/bleeding problems, infections, inflammation of lungs, liver or kidney problems, high cholesterol levels, diabetes, eye problems, if you are taking anticoagulants if you drink alcohol or are alcoholic if you are due to undergo any vaccination or surgery, or if you are over 65 years of age. Consult the doctor if you are pregnant or breastfeeding. TORISEL 25MG INJECTION is not recommended for children below 18 years as the effectiveness has not been established.

Drug-Drug Interactions

TemsirolimusFosphenytoin

Severe

TemsirolimusGentamicin

Severe

Drug-Drug Interactions

TemsirolimusFosphenytoin

Severe

How does the drug interact with Torisel 25mg Injection:
When Torisel 25mg Injection is taken with Fosphenytoin, it can cause Torisel 25mg Injection to be broken down faster in the body. This can lead to low treatment outcomes

How to manage the interaction:
Although taking Fosphenytoin and Torisel 25mg Injection together can evidently cause an interaction, it can be taken if your doctor has suggested it. If you notice any unusual symptoms or if your condition worsens, make sure to contact your doctor right away. Do not stop using any medications without talking to your doctor.

TemsirolimusGentamicin

Severe

How does the drug interact with Torisel 25mg Injection:
Co-administration of Gentamicin and Torisel 25mg Injection may increase the risk of kidney problems.

How to manage the interaction:
Co-administration of Gentamicin with Torisel 25mg Injection can possibly result in an interaction, but it can be taken if a doctor has advised it. It's important to keep an eye on how much you pee. If you notice any changes like peeing more or less than usual, it's a good idea to let your doctor know right away. Some signs to watch out for include gaining weight quickly, feeling bloated, having trouble breathing, or feeling sick to your stomach. Other symptoms to be aware of are not feeling hungry, losing weight, swelling, muscle cramps, feeling weak or dizzy, feeling confused, or having an irregular heartbeat. Do not stop using any medications without a doctor's advice.

TemsirolimusEtodolac

Severe

How does the drug interact with Torisel 25mg Injection:
Taking Etodolac and Torisel 25mg Injection can increase the risk of kidney problems.

How to manage the interaction:
Although there is a possible interaction between Etodolac and Torisel 25mg Injection, you can take these medicines together if prescribed by a doctor. However, consult a doctor if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or an irregular heart rhythm. Do not discontinue any medications without a doctor's advice.

TemsirolimusInfliximab

Severe

How does the drug interact with Torisel 25mg Injection:
When Torisel 25mg Injection is taken with Infliximab, it can lead to or increase the risk or severity of developing serious infections.

How to manage the interaction:
Although there is a possible interaction between Infliximab and Torisel 25mg Injection, you can take these medicines together if prescribed by your doctor. However, if you experience symptoms of fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in sputum, weight loss, red or inflamed skin, body sores, and pain or burning during urination, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

TemsirolimusVoriconazole

Severe

How does the drug interact with Torisel 25mg Injection:
Using Torisel 25mg Injection together with Voriconazole may significantly increase the blood levels and effects of Torisel 25mg Injection.

How to manage the interaction:
Although taking Voriconazole and Torisel 25mg Injection together can cause an interaction, it can be taken if a doctor has suggested it. Do not discontinue any medications without consulting a doctor.

TemsirolimusTofacitinib

Severe

How does the drug interact with Torisel 25mg Injection:
Taking Tofacitinib with Torisel 25mg Injection may increase the risk of infection.

How to manage the interaction:
Although there is a possible interaction between Tofacitinib and Torisel 25mg Injection, you can take these medicines together if prescribed by your doctor. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue any medications without consulting your doctor.

TemsirolimusNaproxen

Severe

How does the drug interact with Torisel 25mg Injection:
Coadministration of Naproxen and Torisel 25mg Injection may increase the risk or severity of kidney problems.

How to manage the interaction:
Taking Naproxen and Torisel 25mg Injection together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm, consult the doctor. Do not discontinue any medication without a doctor's advice.

TemsirolimusVancomycin

Severe

How does the drug interact with Torisel 25mg Injection:
Coadministration of Vancomycin with Torisel 25mg Injection can increase the risk or severity of kidney problems.

How to manage the interaction:
Taking Vancomycin with Torisel 25mg Injection may result in an interaction, they can be taken together if prescribed by a doctor. However, contact a doctor immediately if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not discontinue any medication without consulting a doctor.

Temsirolimusvalacyclovir

Severe

How does the drug interact with Torisel 25mg Injection:
Co-administration of Torisel 25mg Injection with valacyclovir may increase the risk of kidney problems.

How to manage the interaction:
Although taking Torisel 25mg Injection and valacyclovir together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as nausea, vomiting, loss of appetite, increased urination, weight loss, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not stop using any medications without consulting a doctor.

TemsirolimusAmphotericin b

Severe

How does the drug interact with Torisel 25mg Injection:
Coadministration of Amphotericin b and Torisel 25mg Injection may increase the risk of kidney problem.

How to manage the interaction:
Although taking Amphotericin b and Torisel 25mg Injection together can cause an interaction, it can be taken if a doctor has suggested it. If you experience any changes like nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm let the doctor know right away. Do not discontinue any medications without consulting the doctor.

Drug-Food Interactions

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

Diet & Lifestyle Advise

Eat a healthy diet and exercise regularly to maintain proper weight.
Avoid smoking and alcohol consumption.
Include vegetables, whole grains and fruits in your diet.
Avoid fast, fried foods, processed meats, highly processed foods and beverages, and salty snacks.
Get optimal sleep; rest well.

Habit Forming

Therapeutic Class

CHEMOTHERAPY

Alcohol

Consult your doctor

It is not known if alcohol interacts with TORISEL 25MG INJECTION. Please consult the doctor.

Pregnancy

Caution

TORISEL 25MG INJECTION may cause fetal harm when administered to pregnant women. TORISEL 25MG INJECTION should not be used during pregnancy unless clearly necessary. Consult the doctor if you are pregnant, planning for pregnancy, or thinking you may be pregnant.

Breast Feeding

Unsafe

Avoid breastfeeding while using TORISEL 25MG INJECTION and for three weeks after the last dose.

Driving

Safe

TORISEL 25MG INJECTION is unlikely to affect your ability to drive.

Liver

Caution

TORISEL 25MG INJECTION is not recommended in patients with liver problems. Consult the doctor if you have/had liver problems.

Kidney

Caution

Please consult the doctor if you have kidney impairment or any concerns regarding this. Your doctor may monitor kidney function while on treatment with this medicine.

Children

Unsafe

TORISEL 25MG INJECTION is not recommended for children below 18 years as effectiveness has not been established.

Have a query?

FAQs

What is the use of TORISEL 25MG INJECTION?

TORISEL 25MG INJECTION is used to treat Renal cell cancer (Kidney cancer).

How does TORISEL 25MG INJECTION work?

TORISEL 25MG INJECTION works by blocking tumour cell growth and division. Thereby, it helps treat kidney cancer.

Does TORISEL 25MG INJECTION cause infections?

TORISEL 25MG INJECTION may result in immunosuppression, leading to an increased risk of infections. Wash your hands frequently and avoid contact with sick people.

Can I receive vaccinations during treatment with TORISEL 25MG INJECTION?

Vaccination may be less effective if taken during treatment with TORISEL 25MG INJECTION. Also, some vaccinations should be avoided during treatment. Therefore, do not have any vaccinations without consulting the doctor.

Does TORISEL 25MG INJECTION affect fertility?

Fertility may be compromised during treatment with TORISEL 25MG INJECTION. Consult the doctor if you have any concerns.

Country of origin

India

Manufacturer/Marketer address

The Capital, 1802, 18th Floor , Plot No. C-70, ‘G’ Block , Bandra Kurla Complex, Bandra East , Mumbai – 400051.

Other Info - TOR0218

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Author Details

Written By

Santoshini Reddy G

M Pharmacy

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jan 1, 2025 | 9:32 AM IST

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Composition :

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Consume Type :

Return Policy :

Expires on or after :

Drug-Drug Interactions

Drug-Food Interactions

FAQs

What is the use of TORISEL 25MG INJECTION?

How does TORISEL 25MG INJECTION work?

Does TORISEL 25MG INJECTION cause infections?

Can I receive vaccinations during treatment with TORISEL 25MG INJECTION?

Does TORISEL 25MG INJECTION affect fertility?

Disclaimer

Author Details

Reference