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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 11, 2024 | 2:35 PM IST
Topram 2.5 Tablet is used to treat high blood pressure (hypertension) and reduce the risk of having a heart attack, stroke or heart failure. It contains Ramipril, which relaxes and widens the blood vessels, making it easier for the heart to pump blood to all parts of the body, thereby lowering the raised blood pressure and reducing the risk of having a heart attack, stroke or heart failure. In some cases, it may cause common side effects like headache, dizziness, fatigue, and cough. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Composition

RAMIPRIL-2.5MG

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Topram 2.5 Tablet

Topram 2.5 Tablet is used to treat high blood pressure (hypertension) and reduce the risk of having a heart attack, stroke or heart failure. High blood pressure is a chronic condition in which the pressure in the blood vessels is high.

Topram 2.5 Tablet contains 'Ramipril' that relaxes and widens the blood vessels, making it easier for the heart to pump blood to all parts of the body, thereby lowering the raised blood pressure and reducing the risk of having a heart attack, stroke or heart failure.

Take Topram 2.5 Tablet with or without food. Do not chew, crush, or break Topram 2.5 Tablet . Swallow it as a whole with a glass of water. Take Topram 2.5 Tablet at the same time every day. In some cases, Topram 2.5 Tablet may cause common side effects like headache, dizziness, fatigue, and cough. Most of these side effects do not require medical attention and will resolve gradually over time. Talk to your doctor if you experience these side effects persistently.

Try not to stop taking it on your own as it may cause a sudden increase in blood pressure, chest pain or heart attack. Regular monitoring of blood pressure, electrolyte levels, and kidney function is advised while taking Topram 2.5 Tablet . Avoid taking Topram 2.5 Tablet if you are pregnant or breastfeeding. Talk to your doctor, he/she may prescribe you alternate medicine. Topram 2.5 Tablet is not recommended for children below 18 years of age as efficacy and safety have not been established.

Uses of Topram 2.5 Tablet

Treatment of Hypertension (high blood pressure), Prevention of heart attack, stroke, and heart failure.

Medicinal Benefits

Topram 2.5 Tablet is used alone or in combination with other medicines to treat high blood pressure. Topram 2.5 Tablet relaxes and widens the blood vessels, making it easier for the heart to pump blood to all parts of the body. This helps in lowering blood pressure and the risk of having a heart attack or stroke. Topram 2.5 Tablet helps in reducing both standing and lying down blood pressure without any orthostatic effect (sudden decrease in blood pressure which might occur when a person stands up suddenly). However, when dehydrated Topram 2.5 Tablet may show an orthostatic effect. Continued usage of Topram 2.5 Tablet helps in decreasing the severity of heart failure, rate of hospitalization and symptoms such as weakness and shortness of breath.

Directions for Use

Swallow Topram 2.5 Tablet with a glass of water as a whole. Do not crush, break or chew it. Topram 2.5 Tablet can be taken with or without food at the same time daily for best results. Take Topram 2.5 Tablet exactly as prescribed by your doctor. Based on your medical condition, your doctor will advise you on how long you need to take Topram 2.5 Tablet .

Storage

Store in a cool and dry place away from sunlight

Side Effects of Topram 2.5 Tablet

  • Headache
  • Nausea
  • Dizziness
  • Weakness
  • Low blood pressure
  • Inflammation of the sinus (sinusitis)
  • Shortness of breath
  • Stomach pain
  • Diarrhoea
  • Indigestion

Drug Warnings

Do not take Topram 2.5 Tablet if you are allergic to any of its contents. Talk to your doctor if you have heart, kidney or liver problems. Topram 2.5 Tablet may sometimes cause a decrease in blood pressure than normal, especially in dehydrated people, who are taking diuretics (medicines to treat oedema) and have low levels of sodium. Avoid taking Topram 2.5 Tablet if you are pregnant or breastfeeding. Talk to your doctor, he/she may prescribe you alternate medicine. Topram 2.5 Tablet is not recommended for children below 18 years of age as efficacy and safety have not been established. Inform your doctor about all the medicines you are taking and about your health condition to rule out any unpleasant side effects. Consult your doctor if you have lost a lot of body fluids through vomiting, diarrhoea or sweating more than normal or if you are taking low water tablets to treat oedema (diuretics), or if you undergo dialysis. Inform your doctor that you are taking Topram 2.5 Tablet if you are due to undergo any surgery or dental procedure; your doctor may advise you to stop taking Topram 2.5 Tablet one day before receiving an anaesthetic to undergo any surgery or dental procedure.

Drug Interactions

Drug-Drug Interactions: Topram 2.5 Tablet may interact with drugs used to treat severe heart failure (sacubitril/valsartan), pain killers (aspirin, naproxen and ibuprofen), PDE5 inhibitors (sildenafil), a drug used to treat gout (allopurinol), anti-diabetic (sitagliptin, metformin, insulin glargine), diuretics (furosemide), corticosteroid (prednisolone) and anti-convulsant (pregabalin).

Drug-Food Interactions: Maintain low salt and low-fat diet while taking Topram 2.5 Tablet . Avoid consuming food rich in potassium such as potassium-containing salt substitutes or over-the-counter potassium supplements. Avoid smoking and alcohol consumption.

Drug-Disease Interactions: Inform your doctor if you have angioedema (swelling), congestive heart failure (heart problems), hemodialysis, low blood pressure, hyperkalemia (high levels of potassium in the body),  liver diseases and kidney dysfunction.

Drug-Drug Interactions Checker List

  • PREGABALIN
  • ASPIRIN
  • NAPROXEN
  • IBUPROFEN
  • SILDENAFIL
  • ALLOPURINOL
  • SITAGLIPTIN
  • METFORMIN
  • INSULIN
  • FUROSEMIDE
  • PREDNISOLONE

Habit Forming

No

Diet & Lifestyle Advise

  • You are advised to consume low salt and low-fat diet while taking Topram 2.5 Tablet .
  • Regular exercise is also recommended to complement treatment with Topram 2.5 Tablet .
  • Eat a diet rich in whole grains, vegetables, and fruits.
  • Avoid smoking and alcohol consumption.
  • Maintain a healthy weight with proper diet and exercise.
  • Managing stress with meditation, yoga, and massage would also help treat high blood pressure.

Special Advise

  • Get up slowly while rising from lying or sitting position as Topram 2.5 Tablet may cause dizziness.
  • Avoid consuming food rich in potassium such as banana, broccoli, almonds, avocado, and potassium supplements.
  • Regular monitoring of blood pressure, electrolyte levels and kidney functioning is advised while taking Topram 2.5 Tablet .

Disease/Condition Glossary

High blood pressure (hypertension): It is a condition in which the blood exerts increased pressure on the walls of blood vessels, leading to hypertension. This condition can lead to hardened arteries (blood vessels), decreasing the blood and oxygen flow to the heart. Raised blood pressure can cause chest pain (angina) and heart attack (when the blood supply to the heart is blocked). Additionally, high blood pressure also causes brain damage (stroke) and kidney failure. Symptoms of high blood pressure include headache, dizziness, nose bleed, changes in vision, chest pain, weakness and dyspnoea (shortness of breath). However, most of the time, the signs and symptoms of hypertension are none.

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Alcohol

Unsafe

You are recommended to avoid alcohol consumption while taking Topram 2.5 Tablet to avoid unpleasant side-effects. Alcohol intake might interfere with the working of Topram 2.5 Tablet . Please consult your doctor if you have any concerns regarding this.

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Pregnancy

Unsafe

It is not recommended to take Topram 2.5 Tablet while you are pregnant. Please consult your doctor if you have any concerns regarding this, your doctor will decide whether Topram 2.5 Tablet can be given to pregnant women or not.

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Breast Feeding

Unsafe

It is not recommended to take Topram 2.5 Tablet while you are breastfeeding. Please consult your doctor if you have any concerns regarding this, your doctor will decide whether Topram 2.5 Tablet can be given to breast-feeding mothers or not.

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Driving

Caution

Topram 2.5 Tablet may cause dizziness, do not drive or operate heavy machinery if you feel dizzy.

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Liver

Caution

Dose adjustment may be needed. Topram 2.5 Tablet should be used with caution in patients with liver impairment/liver disease. Please consult your doctor if you have any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed. Topram 2.5 Tablet should be used with caution in patients with kidney impairment/kidney disease. Please consult your doctor if you have any concerns regarding this.

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Children

Unsafe

Topram 2.5 Tablet should not be used by children as the efficacy and safety has not been established.

Country of origin

India

Manufacturer/Marketer address

P K 19, Phase V, Industrial Estate, Ekkattuthangal, Chennai - 600 097
Other Info - TOP0118

Author Details

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FAQs

Topram 2.5 Tablet is used to treat high blood pressure (hypertension) and reduce the risk of heart attack, stroke or heart failure.
Topram 2.5 Tablet belongs to the group of medicines called Angiotensin Converting Enzyme (ACE) Inhibitors that works by lowering the body’s production of substances that could increase the blood pressure. Topram 2.5 Tablet relaxes and widens the blood vessels making it easier for the heart to pump blood to all parts of the body. This helps in lowering the blood pressure and the risk of having a heart attack or stroke.
If you are diabetic you should monitor your blood glucose levels often especially in the first few weeks because Topram 2.5 Tablet can lower glucose/sugar levels in blood. However, please consult your doctor before taking Topram 2.5 Tablet if you are diabetic.
Please do not stop taking Topram 2.5 Tablet without consulting your doctor on your own as it may lead to rise in blood pressure. Continue taking Topram 2.5 Tablet for as long as your doctor has prescribed it to you. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Topram 2.5 Tablet .
Orthostatic hypotension could be a side-effect of Topram 2.5 Tablet , especially in people who are dehydrated. Orthostatic hypotension is a sudden lowering in blood pressure leading to dizziness on standing. If you experience this, do not try to stand up suddenly or start walking, instead lie down and get up slowly only when you feel better. People taking Topram 2.5 Tablet are advised to regularly monitor their blood pressure levels to avoid such unpleasant events.
Do not overdose on Topram 2.5 Tablet or any medicine as it could lead to very unpleasant side-effects. Take Topram 2.5 Tablet only as prescribed by your doctor. Overdose of Topram 2.5 Tablet can cause increased heartbeat, dizziness and sleepiness. Rush to your nearest doctor as early as possible if you have overdosed on Topram 2.5 Tablet .
No, it is not a blood thinner. Ramipril is an angiotensin-converting enzyme (ACE) inhibitor. It is utilized for multiple indications, including hypertension and prevention of heart failure progression following a myocardial infarction (MI).
Topram 2.5 Tablet contains Ramipril, which is an angiotensin-converting enzyme (ACE) inhibitor, stimulates the cough reflex.
Ramipril helps to avoid future strokes, heart attacks, and kidney difficulties. It also increases your chances of survival if you take it to treat heart failure or after a heart attack.
Ramipril can cause hyperkaliemia, an unhealthy state that can lead to death. Your doctor will check your potassium levels, especially if you take additional medications. If you develop any potassium-related symptoms, contact your doctor immediately.
Ramipril reduces high blood pressure within a few hours, but full action may take a few weeks.
A dry, persistent cough is a common adverse effect of Ramipril, a medicine used to treat high blood pressure and certain cardiac diseases. This is because ramipril, an angiotensin-converting enzyme (ACE) inhibitor, stimulates the cough reflex. Cough treatment is usually ineffective, but it may ease on its own or resolve after a few days to a month. If it persists, consult the doctor.
Inform your doctor that you are taking Topram 2.5 Tablet if you are due to undergo any surgery or dental procedure; your doctor may advise you to stop taking Topram 2.5 Tablet one day before receiving an anaesthetic to undergo any surgery or dental procedure.
There is no conclusive evidence that Topram 2.5 Tablet affects fertility in men or women. However, Ramipril is not suggested during pregnancy, so consult your doctor if you are attempting to conceive.
Yes, Topram 2.5 Tablet can reduce blood sugar and may interact with antidiabetic medications and insulin. Suppose you have diabetes and are using Ramipril. In that case, you should monitor your blood sugar more frequently, particularly in the first few weeks. Your doctor may also need to change your diabetes treatment plan.
Stopping Topram 2.5 Tablet may cause your blood pressure to rise. This may increase your risk of heart attack and stroke. If you're bothered by side effects, your doctor may be able to prescribe you a different medicine.
Topram 2.5 Tablet is usually considered safe for long-term use. In fact, it works best when taken consistently over time. However, using Ramipril for an extended period may cause your kidneys to function less effectively. Your doctor will use regular blood tests to determine how well your kidneys operate.
Yes, Topram 2.5 Tablet can be taken with or without food.
Topram 2.5 Tablet may cause common side effects like headache, dizziness, fatigue, and cough. Most of these side effects do not require medical attention and will resolve gradually over time. Talk to your doctor if you experience these side effects persistently.
It's not yet known how much Ramipril passes into breast milk, but it's likely to be a small amount. It is unlikely to cause side effects in your baby. However, there is a very small risk that it could also lower your baby's blood pressure. Your doctor might recommend a different medicine for you to take while breastfeeding.
Topram 2.5 Tablet is not recommended in pregnancy. It can affect your baby's kidneys, especially if it's taken in the second and third trimesters of pregnancy. This can result in long-term damage to your baby's kidneys.
Topram 2.5 Tablet can interact with various medicines. So, do not consume any other medications along with Topram 2.5 Tablet unless recommended by the doctor.
Talk to your healthcare professional before taking Topram 2.5 Tablet if you have any underlying medical condition or are taking any medications. Also, ask for advice about precautions and limitations of Topram 2.5 Tablet .
The time it takes to see results with Topram 2.5 Tablet may vary depending on many factors. It is important to follow the recommended dosage and treatment regimen and consult a healthcare professional for ongoing monitoring.
Topram 2.5 Tablet is usually taken orally. Swallow the tablet as a whole with a glass of water. Do not crush, chew or break it. Take it at the same time every day for effective results.
Topram 2.5 Tablet contains Ramipril, an angiotensin-converting enzyme (ACE) inhibitor.
If you forget to take a dose of Topram 2.5 Tablet , take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.
Do not take more than the prescribed dose of Topram 2.5 Tablet , as it may cause an overdose. If you suspect you have taken an overdose, please consult a doctor immediately.

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