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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Nov 10, 2024 | 7:20 PM IST
Topovate MZ Cream is used to reduce swelling, itching, and redness caused due to certain fungal skin infections. It contains Clobetasol and Miconazole (antifungal), which kills fungi and inhibits the release of certain chemical messengers in the body that cause redness, itching, and swelling. Some people may experience dry skin, itching, irritation, redness, or burning sensation at the site of application. Before using this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Consume Type

TOPICAL

Return Policy

Not Returnable

for this medicine

About Topovate MZ Cream

Topovate MZ Cream is a dermatological combination medication used to reduce swelling, itching, and redness caused due to certain fungal skin infections. Fungal infection is a skin disease in which a fungus attacks the skin tissue and causes infection. Fungal infections may be contagious (spread from one person to another).

Topovate MZ Cream contains Clobetasol (corticosteroid) and Miconazole (antifungal). Clobetasol belongs to the class of corticosteroids that work by acting inside skin cells and inhibiting the release of certain chemical messengers in the body that cause redness, itching, and swelling. When the skin reacts to any allergens, such chemicals are released normally. The fungal cell membranes are essential for their survival as they prevent the entry of unwanted substances into the cells and stop the leakage of cell contents. On the other hand, Miconazole belongs to the class of antifungals that works by causing holes in the fungal cell membranes and killing fungi.

Topovate MZ Cream is only for external use. Use Topovate MZ Cream as advised by the doctor. Avoid contact of Topovate MZ Cream with nose, ears, mouth, or eyes. In case Topovate MZ Cream comes in contact with these areas accidentally, rinse with water thoroughly. Some people may experience dry skin, itching, irritation, redness, or burning sensation at the site of application. Most of these side effects of Topovate MZ Cream do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are known to be allergic to Topovate MZ Cream or any other medicines, please tell your doctor. If you are pregnant or a nursing mother, it is advised to consult a doctor before using Topovate MZ Cream. Do not use Topovate MZ Cream in more than prescribed doses, or for a prolonged time as it may cause adverse effects. Do not wrap or cover the treated area with bandages unless advised by your doctor.  Avoid using Topovate MZ Cream for more than 5 days in children and on the face. Do not apply Topovate MZ Cream to broken skin or cuts. Do not swallow Topovate MZ Cream. In case of accidental swallowing, contact a nearby poison control centre or consult a doctor immediately. Avoid smoking or going near naked flames as Topovate MZ Cream catches fire and burns easily. If you have glaucoma, cataracts, diabetes, psoriasis, adrenal gland, or liver problems, inform your doctor before taking Topovate MZ Cream.

Uses of Topovate MZ Cream

Treatment of Skin infections

Medicinal Benefits

Topovate MZ Cream is a combination of two drugs, namely Clobetasol and Miconazole. Topovate MZ Cream is used to reduce swelling, itching, and redness caused due to fungal skin infections. Clobetasol is a corticosteroid that acts inside skin cells and inhibits the release of certain chemical messengers in the body that cause redness, itching, and swelling. When the skin reacts to any allergens, such chemicals are released normally. The fungal cell membranes are essential for their survival as they prevent the entry of unwanted substances into the cells and stop the leakage of cell contents. Miconazole is an antifungal that causes holes in the fungal cell membranes and kills fungi. Thereby, clears fungal infections and provides relief from cracking, burning, scaling, and itching of the skin caused due to infections.

Directions for Use

Topovate MZ Cream is only for external use. Take a small amount of Topovate MZ Cream on the finger and apply as a thin layer on the clean and dry affected area and surrounding skin. Avoid contact of Topovate MZ Cream with nose, mouth or eyes. In case Topovate MZ Cream comes in contact with these areas accidentally, rinse with water thoroughly. Wash your hands before and after using Topovate MZ Cream if your hands are not the affected area to prevent the spread of infection.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Topovate MZ Cream

  • Dry skin

  • Itching, irritation, redness or burning sensation at the site of application

Drug Warnings

Avoid contact of Topovate MZ Cream with nose, mouth, or eyes as it may irritate. In case Topovate MZ Cream comes in contact with these areas accidentally, rinse with water thoroughly. If you are pregnant or a nursing mother, it is advised to consult a doctor before using Topovate MZ Cream. If you are allergic to Topovate MZ Cream or any other medicines, please tell your doctor. Do not apply Topovate MZ Cream to broken skin or cuts. Do not swallow Topovate MZ Cream. In case of accidental swallowing, contact a nearby poison control center or consult a doctor immediately. Avoid smoking or going near naked flames as Topovate MZ Cream catches fire and burns easily. If you have glaucoma, cataracts, diabetes, psoriasis, adrenal gland, or liver problems, inform your doctor before taking Topovate MZ Cream. Topovate MZ Cream is not recommended for use in neonates and infants (up to 2 years) as absorption by immature skin may be enhanced, and kidneys may be immature, leading to toxicity.

Drug Interactions

Drug-Drug Interaction: Topovate MZ Cream may interact with anticoagulants/blood thinner (warfarin, dicumarol, anisindione).

Drug-Food Interaction: Inform your doctor if you are taking any herbal supplements, vitamins or OTC medicines.

Drug-Disease Interaction: If you have glaucoma, cataracts, diabetes, psoriasis, adrenal gland or liver problems, inform your doctor before taking Topovate MZ Cream.

Drug-Drug Interactions Checker List

  • WARFARIN
  • DICUMAROL
  • ANISINDIONE

Habit Forming

No

Diet & Lifestyle Advise

  • Regularly change your socks and wash your feet. Avoid shoes that make your feet sweaty and hot.
  • In wet places such as changing rooms and gym showers, don’t walk on barefoot to prevent fungal infections.
  • Do not scratch the affected area of skin as it can spread the infection to other body parts.
  • Avoid sharing towels, combs, bedsheets, shoes or socks with others.
  • Wash your bed sheets and towels regularly.

Special Advise

Avoid contact of Topovate MZ Cream with nose, mouth or eyes. In case Topovate MZ Cream comes in contact with these areas accidentally, rinse with water thoroughly.

Disease/Condition Glossary

Fungal infection: It is a skin disease in which a fungus attacks the tissue and causes infection. Fungal infections may be contagious (spread from one person to another). The symptoms of a fungal infection include scaly skin, blisters, itching, swelling, irritation, and redness. Antifungal medicines are usually used to treat fungal infections. Avoid sharing things to prevent the spread of infection. Keep the affected area clean and dry, wear flip-flops or sandals in locker rooms and avoid tight-fitting shoes or clothes to prevent fungal infections.

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Alcohol

Caution

Interaction of Topovate MZ Cream with alcohol is unknown. Please consult a doctor before consuming alcohol while using Topovate MZ Cream.

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Pregnancy

Caution

Topovate MZ Cream is Category C pregnancy drug and is given to a pregnant woman only if the doctor thinks benefits outweigh risks.

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Breast Feeding

Caution

It is unknown whether Topovate MZ Cream is excreted in human milk. Please consult a doctor before using Topovate MZ Cream while breastfeeding.

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Driving

Safe if prescribed

Topovate MZ Cream usually does not affect your ability to drive or operate machinery.

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Liver

Caution

If you have any concerns regarding the use of Topovate MZ Cream in patients with Liver problems, please consult a doctor.

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Kidney

Caution

If you have any concerns regarding the use of Topovate MZ Cream in patients with Kidney problems, please consult a doctor.

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Children

Caution

Topovate MZ Cream should be used with caution in children below 12 years if prescribed by a doctor. Topovate MZ Cream is not recommended for use in children below 2 years as in neonates and infants, absorption of Topovate MZ Cream by immature skin may be enhanced and kidney may be immature.

Manufacturer/Marketer address

Zydus Tower, Satellite Cross Roads,Ahmedabad 380015 Gujarat, India.
Other Info - TO61834

Author Details

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FAQs

Topovate MZ Cream is used to reduce swelling, itching, and redness caused by certain fungal skin infections.
No, Topovate MZ Cream is not recommended to treat acne as it may worsen the condition. Topovate MZ Cream is only used to reduce itching, swelling and redness caused due to certain skin infections. However, please consult a doctor before using Topovate MZ Cream.
You are recommended to use Topovate MZ Cream on the face only if advised by your doctor and do not use for more than 5 days on the face as the skin on face thins easily. Avoid the use of dressing or bandages on the face.
Topovate MZ Cream should be used with caution in children if prescribed by a doctor as Topovate MZ Cream contains a steroid and may increase the risk of Cushing’s syndrome, HPA axis suppression (suppression of inflammatory and immune responses), adrenal insufficiency, delayed growth and weight gain. However, please consult a doctor before using Topovate MZ Cream in children.
You are recommended to use Topovate MZ Cream for as long as your doctor has prescribed it. However, if the condition does not improve after 2 to 4 weeks of treatment with Topovate MZ Cream, please consult a doctor.
Yes, Topovate MZ Cream may increase blood sugar levels. Therefore, inform your doctor if you have diabetes before taking Topovate MZ Cream and regularly monitor blood sugar levels while using Topovate MZ Cream.
Yes, fungal infection is a contagious skin condition which spreads from one person to another through direct skin to skin contact or by contact with contaminated soil or surfaces and infected animals. Therefore, it is recommended to avoid close direct contact until the infection is clear and avoid sharing things with the infected person as it can also spread the infection.
No, you are not recommended to stop using Topovate MZ Cream without consulting your doctor as it may worsen the condition or cause recurring infection. Therefore, take Topovate MZ Cream for as long as your doctor has prescribed it and if you experience any difficulty while taking Topovate MZ Cream, please consult your doctor.
Topovate MZ Cream contains Clobetasol (a corticosteroid) and Miconazole (an antifungal). Clobetasol works by inhibiting the release of certain chemical messengers in the body that cause redness, itching, and swelling. These chemicals are normally released when the skin reacts to allergens. On the other hand, Miconazole works by damaging fungal cell membranes, effectively killing the fungi.
The common side effects of Topovate MZ Cream include dry skin, itching, irritation, redness, and a burning sensation at the site of application. Most of these side effects do not require medical attention and will gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.
Do not use Topovate MZ Cream in more than the prescribed doses or for a prolonged period, as this may cause adverse effects. Avoid wrapping or covering the treated area with bandages unless advised by your doctor. Do not apply Topovate MZ Cream to broken skin or cuts. Do not swallow Topovate MZ Cream; in case of accidental swallowing, contact a nearby poison control centre or consult your doctor immediately. Avoid smoking or going near open flames, as Topovate MZ Cream is flammable and burns easily. Avoid contact with eyes or mucous membranes; in case of accidental contact, rinse with water immediately.
No, do not stop using Topovate MZ Cream without consulting your doctor. To treat your condition effectively and prevent a recurrence of infection, continue using Topovate MZ Cream for the prescribed duration.
Using Topovate MZ Cream for a long time or at a higher than the recommended dose can make your skin thinner or cause stretch marks. The medicine may get absorbed into the bloodstream and can lead to serious side effects, such as adrenal gland problems, hyperglycemia (high blood sugar), or problems with your eyesight. If you experience an increase in the severity of your symptoms, please consult your doctor.
Store Topovate MZ Cream in a cool, dry place away from sunlight. Keep it out of reach of children.
Topovate MZ Cream is contraindicated in patients with a known allergy to any of its components. If you are pregnant or a nursing mother, please consult a doctor before using Topovate MZ Cream. It is not recommended for use in neonates and infants (up to 2 years) because absorption by immature skin may be enhanced, and their kidneys may be immature, leading to potential toxicity.

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