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  3. Topgem 320 mg Tablet 5's

Topgem 320 mg Tablet 5's, Pack of 5 TABLETS
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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Topgem 320 mg Tablet is an antibiotic used to treat or prevent certain bacterial infections of nose, throat, urinary tract, lungs (pneumonia), skin, and soft tissues. It contains Gemifloxacin, which kills bacteria and treats the infection. It may cause side effects such as rash, vomiting, headache, dizziness, stomach pain, nausea, and diarrhoea.
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Composition :

GEMIFLOXACIN-320MG

Manufacturer/Marketer :

Torrent Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Topgem 320 mg Tablet

Topgem 320 mg Tablet belongs to a class of drugs known as antibiotics, primarily used to treat or prevent certain infections caused by bacteria. It is used to treat nose, throat, urinary tract infections, lungs (pneumonia), skin, and soft tissues. A bacterial infection is a condition in which bacteria grow in the body and cause infection. It can target any body part and multiple very quickly.

Topgem 320 mg Tablet contains an antibiotic medicine, Gemifloxacin, a broad-spectrum antibiotic used to treat bacterial infections. It works by killing bacteria (bactericidal) that cause infections and prevents the division of bacterial cells. It also inhibits the repairing of bacterial cells. Altogether, it kills bacteria and treats the infection.

Take Topgem 320 mg Tablet as prescribed by your doctor. Depending upon your medical condition, you are advised to take Topgem 320 mg Tablet for as long as your doctor has prescribed it for you. Sometimes, you may experience a rash, vomiting, headache, dizziness, stomach pain, nausea, diarrhoea, and abnormal liver function tests. However, if the side effects are persistent, reach out to your doctor. You should immediately contact a doctor if you experience any allergic reaction symptoms such as rashes, itching, swelling, shortness of breath, etc. 

Do not take Topgem 320 mg Tablet if you are allergic or have had a severe reaction to Topgem 320 mg Tablet. Taking Topgem 320 mg Tablet may increase the chances of developing tendinitis or have a tendon rupture. Taking Topgem 320 mg Tablet may worsen muscle weakness in people with myasthenia gravis (muscle weakness disorder) and cause severe difficulty breathing or death. Dairy products should be avoided along with Topgem 320 mg Tablet. And also, exposure to sunlight should be avoided while taking Topgem 320 mg Tablet as it may cause increased phototoxicity or photosensitivity.

Uses of Topgem 320 mg Tablet

Treatment of Bacterial infections

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Topgem 320 mg Tablet belongs to a class of drugs known as antibiotics, containing Gemifloxacin, primarily used to treat or prevent certain infections caused by bacteria. It is used to treat nose, throat, urinary tract infections, lungs (pneumonia), skin, and soft tissues. It works by killing bacteria (bactericidal) that cause infections and prevents the division of bacterial cells. It also inhibits the repairing of bacterial cells. Altogether, it kills bacteria and treats the infection.

How Topgem 320 mg Tablet Works

Topgem 320 mg Tablet contains an antibiotic medicine, Gemifloxacin, a broad-spectrum antibiotic used to treat bacterial infections. It works by killing bacteria (bactericidal) that cause infections and prevents the division of bacterial cells. It also inhibits the repairing of bacterial cells. Altogether, it kills bacteria and treats the infection.

Storage

Store in a cool and dry place away from sunlight
Side effects of Topgem 320 mg Tablet
  • Skin rash caused by allergies is due to irritants or allergens. Therefore, avoid contact with such irritants.
  • Consult your doctor for proper medication and apply an anti-itch medication. Follow the schedule and use the medication whenever needed.
  • Protect your skin from extreme heat and try to apply wet compresses.
  • Soak in the cool bath, which gives a soothing impact to the affected area.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
  • Avoid trigger foods that can cause allergic reactions, such as nuts, shellfish, or dairy products.
  • Keep a food diary to track potential food allergens.
  • Include omega-3 rich foods like salmon and walnuts to reduce inflammation.
  • Wear loose, comfortable clothing made from soft fabrics like cotton.
  • Apply cool compresses or take cool baths to reduce itching.
  • Use gentle soaps and avoid harsh skin products.
  • Reduce stress through relaxation techniques like meditation or deep breathing.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.

What if I have taken an overdose of Topgem 320 mg Tablet

Do not take more than the prescribed dose of Topgem 320 mg Tablet as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

Do not take Topgem 320 mg Tablet if you are allergic or have had a severe reaction to Topgem 320 mg Tablet. Taking Topgem 320 mg Tablet may increase the chances of developing tendinitis (swelling of a fibrous tissue that connects a bone to a muscle) or having a tendon rupture (tearing of a fibrous tissue that connects a bone to a muscle). Inform your doctor if you have or have ever had a kidney or liver disease, heart, or lung transplant, rheumatoid arthritis, seizures (fits), epilepsy or if you participate in regular physical activity. Topgem 320 mg Tablet should only be used if a safer antibiotic does not cure the infection. Taking Topgem 320 mg Tablet may worsen muscle weakness in people with myasthenia gravis (a nervous system disorder that causes muscle weakness) and cause severe difficulty breathing or death. Dairy products should be avoided along with Topgem 320 mg Tablet. And also, exposure to sunlight should be avoided while taking Topgem 320 mg Tablet as it may cause increased phototoxicity or photosensitivity. Patients with epilepsy and irregular heartbeat (especially a condition known as QT prolongation) should tell their doctor before taking Topgem 320 mg Tablet.

Drug-Drug Interactions

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GemifloxacinZiprasidone
Critical
GemifloxacinWarfarin
Severe

Drug-Drug Interactions

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GemifloxacinZiprasidone
Critical
How does the drug interact with Topgem 320 mg Tablet:
Coadministration of Topgem 320 mg Tablet with Ziprasidone can increase the risk of abnormal heart rhythm.

How to manage the interaction:
Taking Ziprasidone with Topgem 320 mg Tablet is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
GemifloxacinWarfarin
Severe
How does the drug interact with Topgem 320 mg Tablet:
Coadministration of Warfarin with Topgem 320 mg Tablet can increase the risk of bleeding.

How to manage the interaction:
Although taking Topgem 320 mg Tablet and Warfarin together can result in an interaction, they can be taken together if prescribed by a doctor. However, if you experience unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness consult a doctor immediately. Do not stop using any medications without consulting a doctor.
GemifloxacinSevelamer
Severe
How does the drug interact with Topgem 320 mg Tablet:
Topgem 320 mg Tablet's efficiency can be decreased by sevelamer if it prevents the drug from being absorbed into the bloodstream. this is caused by the combined use of Topgem 320 mg Tablet and sevelamer.

How to manage the interaction:
Co-administration of enoxacin and sevelamer can lead to an interaction, but it can be taken if your doctor advises. It has been advised to separate the dosing of these medications by at least 4 hours and consult the doctor if your symptoms do not improve. Do not stop using any medications without a doctor's advice.
GemifloxacinBetamethasone
Severe
How does the drug interact with Topgem 320 mg Tablet:
Taking Topgem 320 mg Tablet may cause tendinitis and tendon rupture, and the risk may be increased when combined with Betamethasone.

How to manage the interaction:
Although there is an interaction, betamethasone can be taken with Topgem 320 mg Tablet if prescribed by the doctor. Consult the prescriber if you experience pain, inflammation, or swelling of a tendon area such as the back of the ankle, biceps, shoulder, hand, or thumb. Do not discontinue the medication without consulting a doctor.
GemifloxacinFludrocortisone
Severe
How does the drug interact with Topgem 320 mg Tablet:
Combining Fludrocortisone with Topgem 320 mg Tablet can increase the risk of tendinopathy.

How to manage the interaction:
Co-administration of Fludrocortisone with Topgem 320 mg Tablet can possibly result in an interaction, but it can be taken if your doctor has advised it. This risk is higher if you are also taking oral corticosteroids. Contact your doctor immediately if you experience tendinitis (Inflammation to muscle present in hand), tendon rupture, prolonged disability, pain, swelling, or inflammation. Do not discontinue any medications without consulting your doctor.
GemifloxacinInsulin detemir
Severe
How does the drug interact with Topgem 320 mg Tablet:
Co-administration of Topgem 320 mg Tablet and Insulin detemir can have an impact on blood sugar levels. There have been reports of both hyperglycemia (high blood sugar) and, less frequently, hypoglycemia (low blood sugar).

How to manage the interaction:
Although taking Topgem 320 mg Tablet and Insulin detemir together can possibly result in an interaction, it can be taken if a doctor has prescribed it. However, consult a doctor, if you experience headaches, dizziness, sleepiness, anxiety, disorientation, tremors, nausea, hunger, weakness, sweat, palpitations, and rapid heartbeat, increased hunger, thirst, and urine. It is recommended to maintain blood glucose levels. Do not discontinue any medications without a doctor's advice.
GemifloxacinInsulin glulisine
Severe
How does the drug interact with Topgem 320 mg Tablet:
Taking insulin glulisine with Topgem 320 mg Tablet affects blood glucose levels, which may cause hyperglycemia (high blood sugar) and hypoglycemia (low blood sugar) less frequently.

How to manage the interaction:
Although taking Topgem 320 mg Tablet and Insulin glulisine together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience hypoglycemia or hyperglycemia. Symptoms of hypoglycemia include headache, dizziness, drowsiness, nervousness, confusion, shaking, nausea, loss of hunger, weakness, sweating, palpitations, and rapid heartbeat. Symptoms of hyperglycemia may include increased thirst, increased hunger, and increased urination. Do not stop using any medications without first talking to your doctor.
GemifloxacinHydrocortisone
Severe
How does the drug interact with Topgem 320 mg Tablet:
Taking Topgem 320 mg Tablet and hydrocortisone together can cause tendinitis and tendon rupture.

How to manage the interaction:
Co-administration of Topgem 320 mg Tablet and hydrocortisone can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like pain, swelling, or inflammation of a tendon area such as the back of the ankle, shoulder, biceps, hand, or thumb, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
GemifloxacinMifepristone
Severe
How does the drug interact with Topgem 320 mg Tablet:
Co-administration of Topgem 320 mg Tablet with mifepristone can increase the risk of irregular heart rhythms.

How to manage the interaction:
Taking Topgem 320 mg Tablet with mifepristone together is avoided as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience any symptoms such as dizziness, lightheadedness, fainting, shortness of breath, or irregular heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
GemifloxacinHaloperidol
Severe
How does the drug interact with Topgem 320 mg Tablet:
Co-administration of Topgem 320 mg Tablet and Haloperidol can increase the risk or severity of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Co-administration of Topgem 320 mg Tablet and Haloperidol can lead to an interaction, it can be taken when advised by your doctor. However, if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, heart palpitations, diarrhea, or vomiting, contact your doctor immediately. Do not discontinue any medications without consulting your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Do not drink or eat a lot of caffeine-containing products such as coffee, tea, energy drinks, cola, or chocolate. Topgem 320 mg Tablet may increase nervousness, sleeplessness and anxiety caused by caffeine.
  • Probiotics should be taken after taking the full course of Topgem 320 mg Tablet to restore some healthy bacteria in the intestines that may have been killed. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhoea. Certain fermented foods like yoghurt, cheese, sauerkraut, kombucha, and kimchi can help restore the intestine's good bacteria. 
  • Include more fibre-enriched food in your diet, as it can be easily digested by gut bacteria, which helps stimulate their growth. Thus, fibre-rich foods may help restore healthy gut bacteria after antibiotics. Whole grains like whole-grain bread and brown rice should be included in your diet. Make sure you drink plenty of water or other fluids daily while taking Topgem 320 mg Tablet.
  • Avoid alcoholic beverages with Topgem 320 mg Tablet as they can make you dehydrated and may affect your sleep. This can make it harder for your body to aid the Topgem 320 mg Tablet in fighting off infections.

Habit Forming

No

Therapeutic Class

ANTIBIOTICS

Topgem 320 mg Tablet Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Caution

Alcohol is not known to cause any unpleasant side effects if taken along with Topgem 320 mg Tablet. But intake of alcohol with Topgem 320 mg Tablet may damage your liver. So intake of Topgem 320 mg Tablet should be avoided with Topgem 320 mg Tablet.

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Pregnancy

Caution

Topgem 320 mg Tablet is a pregnancy Category C medicine. It is not known whether Topgem 320 mg Tablet will affect pregnant women or fetus or not. Hence, the intake of Topgem 320 mg Tablet should be avoided if you are pregnant or planning to become pregnant as it may harm the baby.

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Breast Feeding

Caution

Topgem 320 mg Tablet is excreted in human milk. But the amount of Topgem 320 mg Tablet absorbed by the nursing infant is unknown. So, it should not be taken while breastfeeding.

bannner image

Driving

Caution

Topgem 320 mg Tablet can affect alertness and coordination. So, operating machinery which requires concentration should be avoided.

bannner image

Liver

Caution

Topgem 320 mg Tablet to be taken with caution, especially if you have a history of liver diseases/conditions. Your doctor may have to adjust the dose if there are symptoms of nausea, vomiting, loss of appetite, dark-coloured urine, or yellowing of skin/eye.

bannner image

Kidney

Caution

Topgem 320 mg Tablet to be taken with caution, especially if you have a history of Kidney diseases/conditions. The dose may have to be adjusted by your doctor.

bannner image

Children

Caution

The safety and efficacy of Topgem 320 mg Tablet are not studied in children below the age of 18 years.

Have a query?

FAQs

Topgem 320 mg Tablet is used to treat or prevent certain infections caused by bacteria. It is used to treat nose, throat, urinary tract infections, lungs (pneumonia), skin, and soft tissues.

Topgem 320 mg Tablet belongs to a class of drugs known as antibiotics, containing Gemifloxacin, which works by killing bacteria (bactericidal) that cause infections and prevent bacterial cell division. It also inhibits the repairing of bacterial cells. Altogether, it kills bacteria and treats the infection.

Topgem 320 mg Tablet makes your skin sensitive to sunlight, known as photosensitivity. So, prolonged exposure to sunlight or ultraviolet light should be avoided. In case of emergency, you should always wear sunscreen before going out.

A common side effect of Topgem 320 mg Tablet is diarrhoea, but you should complete your course. If diarrhoea persists and you observe blood in your stools, please visit your doctor.

No, Topgem 320 mg Tablet should not be taken along with dairy products as it might affect the absorption and efficacy of Topgem 320 mg Tablet. However, you can take it with a meal that includes these foods or drinks.

No. Topgem 320 mg Tablet is an antibacterial medicine that acts only against bacterial infections and not against viral infections causing cold and flu. You should not take Topgem 320 mg Tablet without prior consulting your doctor. Self-medication is dangerous and can lower the efficacy of Topgem 320 mg Tablet, leading to antibiotic resistance.

No, a minimum gap of 2-3 hours should be maintained between the dose of Topgem 320 mg Tablet and antacid as an antacid is known to decrease the absorption and effectiveness of Topgem 320 mg Tablet.

Topgem 320 mg Tablet is known to increase the risk of tendinitis and tendon rupture in all ages. But, the elderly are at increase risk of getting it. So, only take Topgem 320 mg Tablet if prescribed by a doctor in exact dose and duration.

Country of origin

India

Manufacturer/Marketer address

Off. Ashram Road, Ahmedabad - 380 009., Gujarat, India
Other Info - TOP0072

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Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jan 1, 2025 | 2:48 PM IST

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Reference

  1. https://www.drugs.com/mtm/gemifloxacin.html
  2. https://www.accessdata.fda.gov/drugsatfda_docs/label/2008/021158s013lbl.pdf
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