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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 11, 2024 | 2:34 PM IST
Topex DX Syrup is a combination medicine which belongs to the class of expectorants. It is used in the treatment of dry cough. This medicine works by preventing nerve signals from the brain's cough centre from reaching the muscles that cause coughing and thus reduce cough. You may experience common side effects like headache, dizziness, numbness, drowsiness, or nausea.
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Prescription drug

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Prescription drug
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Manufacturer/Marketer

Ozone Pharmaceuticals Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Topex DX Syrup

Topex DX Syrup is used to treat cough due to runny nose, sneezing, and throat irritation. Coughing (dry or productive) is the body's way of clearing irritants (like allergens, mucus or smoke) from airways and preventing infection. There are two types of coughs, namely: Dry cough and chesty cough. A dry cough is tickly and doesn't produce any vicious or thick mucus, while a chesty cough (wet cough) produces mucous or sputum. 

Topex DX Syrup is a combination of two drugs: Chlorphenamine maleate and Dextromethorphan hydrobromide. Chlorphenamine maleate works by blocking the action of histamine, a substance responsible for causing allergic reactions.  Dextromethorphan hydrobromide blocks the transmission of nerve signals from the cough centre in the brain to the muscles that produce cough. Together, Topex DX Syrup helps to relieve cough, cold and allergic symptoms. 

Your doctor will recommend the dose and duration of Topex DX Syrup based on your medical condition. Some people may experience dry mouth/throat/nose, drowsiness, blurred vision, constipation, dizziness, and restlessness. Most of these side effects of Topex DX Syrup do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are pregnant or breastfeeding, it is advised to inform your doctor before starting Topex DX Syrup . Topex DX Syrup is not recommended for children below 2 years of age. Topex DX Syrup may cause dizziness, so drive only if you are alert. Avoid alcohol consumption along with Topex DX Syrup as it may cause increased dizziness and drowsiness. Keep your doctor informed about your health condition and medications to rule out any side effects/interactions.

Uses of Topex DX Syrup

Treatment of Cough

Medicinal Benefits

Topex DX Syrup is a combination of two drugs: Chlorphenamine maleate (antihistamine) and Dextromethorphan hydrobromide (cough suppressant). Chlorphenamine maleate belongs to the class of antihistamines or anti-allergic that work by blocking the action of histamine, a substance responsible for causing allergic reactions. It helps to provide relief from allergy symptoms such as sneezing, running nose, watery eyes, itching, swelling, and congestion or stiffness. Dextromethorphan hydrobromide belongs to the class of cough suppressants that block the transmission of nerve signals from the cough centre in the brain to the muscles that produce cough. Thus, together Topex DX Syrup helps to relieve cough, cold and allergic symptoms.

Directions for Use

Shake the bottle well before use. Take the prescribed dose by mouth using the measuring cup/dosing syringe/dropper provided by the pack.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Topex DX Syrup

  • Dry mouth, throat or nose
  • Drowsiness
  • Blurred vision
  • Constipation
  • Dizziness
  • Restlessness

Drug Warnings

Do not take Topex DX Syrup if you are allergic to any of the contents. Avoid using Topex DX Syrup if you have taken medicines such as linezolid, phenelzine, selegiline, rasagiline, isocarboxazid, tranylcypromine, and methylene blue injection in the past 14 days. It is advised to seek medical help if the cough does not go away or if it is followed by a high fever, skin rash, or persistent headache. Topex DX Syrup may cause drowsiness, dizziness, and blurred vision in some patients; therefore, drive only if you are alert. Topex DX Syrup should not be used in elderly patients with confusion. Avoid alcohol consumption along with Topex DX Syrup as it might cause increased dizziness.

Drug Interactions

Drug-Drug Interaction: Topex DX Syrup may interact with anti-allergic drugs (diphenhydramine), antidepressants (escitalopram, desvenlafaxine, vilazodone).

Drug-Food Interaction: No interactions found/established.

Drug-Disease Interaction: Inform your doctor if you have glaucoma, urinary problems, enlarged prostate, phenylketonuria (a congenital disability that causes accumulation of amino acid, phenylalanine in the body), cough with mucus or cough caused by asthma, smoking, chronic bronchitis, or emphysema (a lung condition causing shortness of breath).

Drug-Drug Interactions Checker List

  • DIPHENHYDRAMINE
  • ESCITALOPRAM
  • DESVENLAFAXINE
  • VILAZODONE

Habit Forming

No

Diet & Lifestyle Advise

  • Avoid dairy products such as milk as they may increase mucus production. Also, avoid processed or refined foods. Instead, replace baked foods, fried foods, white bread, white pasta, french fries, sugary desserts, and chips with green leafy vegetables.

  • Drink plenty of fluids to avoid a dry throat. It also helps loosen mucus.

  • Avoid citrus fruits as they may worsen the cough.

  • Eat fruits rich in water content, such as pears, watermelon, peaches, and pineapples.

Special Advise

  • Talk to your doctor if the symptoms do not improve even after taking Topex DX Syrup for 7 days.
  • Contact a doctor immediately if you develop fever, rash, or headache after taking Topex DX Syrup . 
  • If you are about to undergo any medical tests or surgery, please inform your doctor that you are taking Topex DX Syrup .

Disease/Condition Glossary

Cough: Coughing is the body's way of clearing irritants (like allergens, mucus, or smoke) from airways and preventing infection. Cough may be dry or productive. A productive cough (wet cough) brings up sputum (phlegm, mucus, and other matter) from the lungs. A dry cough does not produce any mucus or phlegm. It usually occurs due to irritation in the airways. Cough is commonly caused as a response to allergy or viral infection, but coughing up mucus is possibly an indication of infection in the respiratory tract. 

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Alcohol

Unsafe

Topex DX Syrup may increase the effects of alcohol, so it is advised to avoid alcohol consumption.

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Pregnancy

Caution

Consult a doctor if you have any concerns regarding this. Your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Please consult a doctor if you have any concerns. Your doctor will decide if Topex DX Syrup can be taken by breastfeeding mothers or not.

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Driving

Caution

Topex DX Syrup may cause dizziness and drowsiness. Therefore, drive only if you are alert after taking Topex DX Syrup .

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Liver

Caution

Take Topex DX Syrup with caution, especially if you have a history of liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take Topex DX Syrup with caution, especially if you have a history of kidney diseases/conditions. The dose may be adjusted by your doctor as required in severe kidney disease.

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Children

Caution

Topex DX Syrup is not recommended for children below 2 years of age. However, it can be used by children older than 2 years of age if prescribed by a child specialist.

Country of origin

INDIA

Manufacturer/Marketer address

Ozone House, Block A-3, 1 LSC, Janak Puri, New Delhi – 110058
Other Info - TOP0338

Author Details

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FAQs

Topex DX Syrup is used to treat cough due to runny nose, sneezing, and throat irritation.
Topex DX Syrup contains Chlorphenamine maleate and Dextromethorphan hydrobromide. Chlorphenamine maleate blocks the action of histamine, a substance responsible for causing allergic reactions. Dextromethorphan hydrobromide works by blocking the transmission of nerve signals from the cough centre in the brain to the muscles that produce cough. Thus, decreasing the urge to cough.
Topex DX Syrup may be used to relieve allergic symptoms such as sneezing, runny nose, throat irritation, or watery eyes. Topex DX Syrup contains Chlorphenamine maleate, an anti-allergic drug that works by blocking the action of histamine, a substance responsible for causing allergic reactions.
Topex DX Syrup may cause dry mouth as a temporary side effect in some people. It is not necessary for everyone taking Topex DX Syrup to experience this side effect. However, to avoid such side effects, drink plenty of water, regularly rinse your mouth, practice good oral hygiene and suck on sugarless candy. However, if the condition persists or worsens, please consult a doctor.
You are recommended to take Topex DX Syrup for as long as your doctor has prescribed it. However, if the symptoms persist or worsen even after one week of using Topex DX Syrup , please consult your doctor.
It is advised not to stop taking Topex DX Syrup without consulting your doctor as it may worsen the cough or cause recurring symptoms. Therefore, take Topex DX Syrup for as long as your doctor has prescribed it, and if you experience any difficulty while taking Topex DX Syrup , please consult your doctor.
Caution should be advised while using Topex DX Syrup in people with Prostate problems. So, it should be taken only under the supervision of the doctor.
Topex DX Syrup should not be taken along with medicines called monoamine oxidase inhibitors (MAOIs), which are used in the treatment of psychiatric illness.
Topex DX Syrup is not recommended for children below 2 years of age. However, it can be used by children older than 2 years of age if prescribed by a child specialist.
Caution should be advised while using Topex DX Syrup in people with eye problems. It should be taken only under the supervision of the doctor.
Yes, Topex DX Syrup is a good option to treat dry cough.
Symptoms, such as cough and congestion, are usually relieved within 30 minutes to an hour of taking the Topex DX Syrup , depending on the individual's response and the intensity of the symptoms.
Topex DX Syrup is a combination of two drugs: Chlorphenamine maleate and Dextromethorphan hydrobromide.
No, taking more than the prescribed dose may not be more effective; it may raise the possibility of experiencing severe adverse reactions.
There is no substantial research yet on using Topex DX Syrup in breastfeeding mothers. If you are a nursing mother, let your doctor know before taking Topex DX Syrup ; your doctor will decide whether breastfeeding mothers can take it or not.
Yes, Topex DX Syrup may make you feel sleepier or drowsy.
Topex DX Syrup is safe to use if the doctor prescribes it, but it has specific limitations.
No, Topex DX Syrup is not an antibiotic medication. It is a combination of an antihistamine and an antitussive.
No, it is not recommended to treat fever. It is intended to treat cough.
Topex DX Syrup should be taken for the duration prescribed by the doctor based on your condition. Usually, it is taken every 8-12 hours.
The timing of taking Topex DX Syrup can vary depending on the specific instructions your healthcare professional provides.
Common side effects of Topex DX Syrup may include dry mouth/throat/nose, drowsiness, blurred vision, constipation, dizziness, and restlessness. Most of these side effects of Topex DX Syrup do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

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