Topentex-50 Tablet is used to alleviate moderate to severe pain. Pain is an unpleasant sensory and expressive experience caused by real or potential tissue injury.

Topentex-50 Tablet composed of Tapentadol; it acts directly on opioid receptors in the central nervous system, reducing feelings of pain by interfering with the way neurons convey pain between the brain and the body.

Topentex-50 Tablet should be taken only if prescribed by the doctor. The possible common side effects of Topentex-50 Tablet are constipation, nausea, sleepiness, vomiting, tiredness, headache, dizziness, and abdominal pain. Report to your healthcare provider if any of these symptoms persist or worsen.

Inform your doctor if you are allergic to any content of this medicine before taking Topentex-50 Tablet . If you have asthma or breathing problems, gastrointestinal obstruction, and paralysis of the gut or ileus, please let your doctor know before prescribing Topentex-50 Tablet to you. Inform your doctor if you are experiencing acute poisoning from alcohol, sleeping pills, pain relievers, or other psychotropic medications. If you are pregnant, planning for pregnancy or breastfeeding, consult your doctor before taking this medicine. Do not discontinue Topentex-50 Tablet without first consulting your doctor, and your doctor may gradually reduce the dose to avoid withdrawal symptoms.

Topentex-50 Tablet is a strong painkiller that belongs to the class of opioids and is used for treating moderate to severe pain. Topentex-50 Tablet acts directly on opioid receptors in the central nervous system, reducing feelings of pain by interfering with the way neurons convey pain between the brain and the body. Thus, it relieves the pain that occurs due to various medical conditions.

• Nausea
• Dizziness
• Vomiting
• Somnolence
• Decreased appetite
• Anxiety
• Confusion
• Hallucination
• Sleep problem
• Abnormal dreams
• Trembling
• Flushing
• Constipation
• Diarrhoea
• Indigestion
• Dry mouth
• Itching
• Increased sweating
• Rash
• Muscle cramps
• Feeling of weakness
• Fatigue
• Feeling of body temperature change

If you are hypersensitive or allergic to any of the ingredients in Topentex-50 Tablet , do not take it. Please do not stop taking Topentex-50 Tablet without first consulting your doctor, as this may result in withdrawal symptoms. If you are pregnant or nursing, do not take the Topentex-50 Tablet unless your doctor has recommended it. Topentex-50 Tablet may cause drowsiness and blurred vision; therefore, drive only if you are awake. Topentex-50 Tablet is not recommended for children because its safety and effectiveness have not been proven. Drinking alcohol while taking Topentex-50 Tablet may cause drowsiness and fatigue. If you are having suicidal thoughts, consult a doctor right away.

Drug-Drug Interactions: Topentex-50 Tablet may interact with certain antidepressants or antipsychotics (e.g. duloxetine, venlafaxine, escitalopram, desvenlafaxine, quetiapine, linezolid), tricyclic antidepressants (e.g. amitriptyline), anticonvulsant (e.g. pregabalin), narcotic analgesics (e.g. naloxone, oxycodone), medicine for anxiety and seizures (e.g. diazepam, alprazolam).

Drug-Food Interactions: Avoid the consumption of alcoholic beverages.

Drug-Disease Interactions: Topentex-50 Tablet interacts with disease conditions including impaired GI motility, infectious diarrhoea, liver disease, prematurity, acute alcohol intoxication, drug dependence, gastrointestinal obstruction, hypotension, intracranial pressure, respiratory depression, biliary spasm, renal dysfunction, seizure disorders, and urinary retention.

• DULOXETINE
• DESVENLAFAXINE
• LINEZOLID
• PREGABALIN
• NALOXONE
• OXYCODONE
• DIAZEPAM
• ALPRAZOLAM

• Include vitamin B and D-rich foods in your diet.

• Exercising regularly helps to improve overall health and combat pain.

• Rest well and get plenty of rest.

• Taking a warm bath can be very relaxing.

• Avoid smoking and drinking alcohol.

• Meditation and yoga can reduce stress and pain sensitivity and improve coping skills.

• Acupuncture, by stimulating pressure points, can be beneficial.

• Massages with essential oils can help increase circulation.

• Do not take Topentex-50 Tablet for longer than it is prescribed because repeatedly using it may make your body dependent on it. If you stop taking Topentex-50 Tablet suddenly, it can cause withdrawal symptoms such as restlessness and irritability. The doctor will recommend that you reduce your dose slowly to prevent the risk of withdrawal effects.

• Topentex-50 Tablet is a controlled drug, and you must take a prescription while travelling abroad.

Pain: Pain is a symptom triggered by the nervous system, causing uncomfortable sensations in the body. Pain may be dull or sharp, constant, or may come and go. The tolerance level of pain might vary from person to person. Pain can be generalized (overall body aches) or localized (affecting a specific body area). Pain can be considered a good thing as it helps us know something is wrong in the body and helps diagnose the condition. The common causes of pain include headache, muscle strain, cramps, cuts, bone fractures and arthritis.