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Written By Veda Maddala , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Topamac 100 mg Tablet is primarily indicated in the treatment of epilepsy and it can also be taken to prevent migraine. It contains Topiramate, which works by controlling the electrical activity of the brain. Thereby, it controls seizures and relieves the symptoms of migraine. It may cause side effects such as feeling sleepy, dizziness, diarrhoea and feeling sick. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Composition :

TOPIRAMATE-100MG

Manufacturer/Marketer :

Janssen Pharmaceuticals Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

Jan-27

About Topamac 100 mg Tablet

Topamac 100 mg Tablet belongs to a group of medicines called “antiepileptic (AED)/ anticonvulsant agent' that is primarily indicated in the treatment of epilepsy (Monotherapy and Adjunctive therapy) and It can also be taken to prevent migraine. Epilepsy is a chronic disorder that is responsible for causing unprovoked, recurrent seizures in the body. A seizure is a sudden attack in the brain that makes a person lose control of their actions. Migraine is a mental condition that often causes intense or debilitating headaches with difficulty speaking, nausea, vomiting, and sensitivity to light or sound.

Topamac 100 mg Tablet is responsible for restoring the balance of neural activity by diminishing the spread of seizure movement in the brain. By controlling the electrical activity of the brain, it controls seizures and relieves the symptoms of migraine. Take Topamac 100 mg Tablet in an empty stomach without food with one glass of water. Topamac 100 mg Tablet is only available on prescription. It comes as tablets or capsules intended to be taken by mouth only. Swallow the medication as a whole without crushing or breaking it. Topamac 100 mg Tablet doses are sometimes advised according to the weight of children so the doctor will change the dose if the child gains or lose weight.

The possible side effects of topiramate include feeling sleepy, dizziness, diarrhoea and feeling sick. Some of the side effects do not even require medical attention and these are usually mild and go away by themselves. Consult with the doctor if any of these side effects continue or get worse with time.

The use of $mame is restricted in persons who are hypersensitive to it, so tell your doctor if you have any allergy to any of the chemical constituents present in this medicine. Tell your doctor if you ever had or already dealing with diarrhoea, glaucoma, metabolic acidosis, lung disease, breathing problems, liver disease, a blood disorder called acute porphyria etc. If a woman is pregnant or planning to pregnant then they should tell their doctor as the use of this medicine during pregnancy may increase the risk of cleft lip and/or cleft palate which is a birth defect in the newborn that may develop during early pregnancy.

Uses of Topamac 100 mg Tablet

Treatment of Epilepsy, Migraine.

Directions for Use

Tablet: It can be taken irrespective of meals. Swallow the tablet as a whole with a glass of water. Do not chew the tablet. Sprinkle capsule: You may swallow the capsule as a whole or you may open the capsule and sprinkle the entire contents on a teaspoon of soft food. Drink fluids immediately after eating this medicine and food mixture to make sure it is swallowed. Do not store this mixture for later use.

Medicinal Benefits

Topamac 100 mg Tablet is an antiepileptic (AED) medicine that is used to treat epilepsy in mono or adjunctive therapy and migraine. In Monotherapy epilepsy, Topamac 100 mg Tablet is suggested for patients above 2 years of age with partial-onset or primary generalized tonic-clonic seizures. In Adjunctive therapy epilepsy, Topamac 100 mg Tablet is suggested in patients of 2 to 16 years of age with partial-onset seizures or primary generalized tonic-clonic seizures while in patients more than 2 years of age, Topamac 100 mg Tablet is suggested in patients with seizures associated with Lennox-Gastaut syndrome (LGS). In migraine, Topamac 100 mg Tablet is suggested for prophylaxis of migraine. Topamac 100 mg Tablet works by blocking the voltage-dependent sodium and calcium channels and increasing the inhibitory actions of GABA. In epilepsy, Topamac 100 mg Tablet controls the uncontrolled activity of nerves in the brain and thus prevents or controls seizures. While in migraine, Topamac 100 mg Tablet tranquilizes the overactive nerve cells in the brain that are responsible for causing migraine.

How Topamac 100 mg Tablet Works

Topamac 100 mg Tablet is responsible for restoring the balance of neural activity by diminishing the spread of seizure movement in the brain. By controlling the electrical activity of the brain, it controls seizures and relieves the symptoms of migraine.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Topamac 100 mg Tablet

  • Tingling of the arms and legs
  • Not feeling hungry
  • Nausea
  • Change in taste
  • Diarrhoea
  • Weight loss
  • Nervousness
  • Upper respiratory tract infection

What if I have taken an overdose of Topamac 100 mg Tablet

Do not take more than the prescribed dose of Topamac 100 mg Tablet as it may cause overdose. The symptoms of overdose include drowsiness, blurred vision, speech disturbance, convulsions (fits), double vision, abnormal coordination, stupor (a state of insensibility or near-unconsciousness), stomach pain, low blood pressure, lethargy, mentation impaired, depression, agitation and dizziness. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

Topamac 100 mg Tablet may cause a congenital disability called cleft lip in unborn baby, so the use of this medicine is not allowed in pregnant females. Topamac 100 mg Tablet may increase the body temperature and reduce sweating, so one should report it to the doctor if they are noticing decreased sweating and hot, dry skin. Topamac 100 mg Tablet may enhance the level of acid in the blood so one should tell their doctor if they have irregular heartbeats or loss of hunger. Before taking Topamac 100 mg Tablet , tell the doctor if you have diarrhoea, metabolic acidosis, eye problems, liver disease. Topamac 100 mg Tablet may affect the working of contraceptives that include the combined pill, vaginal ring, patches,progestogen-only contraceptive pill, and emergency contraception. So, one should tell their doctor if they are using any contraceptives to prevent pregnancy.

Drug-Drug Interactions

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TopiramateChlorpromazine
Severe
TopiramateMedroxyprogesterone
Severe

Drug-Drug Interactions

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TopiramateChlorpromazine
Severe
How does the drug interact with Topamac 100 mg Tablet:
Topamac 100 mg Tablet can cause increased body temperature and decreased sweating, and these effects may be worsened when combined with medications like chlorpromazine.

How to manage the interaction:
Taking chlorpromazine and Topamac 100 mg Tablet together can result in an interaction; it can be taken if a doctor has advised it. Drink plenty of water. If your sweating isn't as much or you have a fever, sleepy, uncomfortable, or lightheaded, you should see a doctor. Avoid activities like operating potentially risky machinery or driving. Do not stop using any medications without a doctor's advice.
TopiramateMedroxyprogesterone
Severe
How does the drug interact with Topamac 100 mg Tablet:
When Medroxyprogesterone acetate is taken with Topamac 100 mg Tablet, it reduces the blood levels and effects of Medroxyprogesterone.

How to manage the interaction:
Co-administration of Medroxyprogesterone with Topamac 100 mg Tablet can possibly result in an interaction, but it can be taken if your doctor has advised it. If you're taking birth control and experiencing symptoms like hot flashes, vaginal dryness, or abnormal bleeding, contact your doctor. Do not stop using any medications without talking to your doctor.
TopiramatePhenylephrine
Severe
How does the drug interact with Topamac 100 mg Tablet:
Co-administration of Topamac 100 mg Tablet can cause increased body temperature and decreased sweating, and these effects may be worsened when combined with medications like Phenylephrine.

How to manage the interaction:
Although there is a possible interaction between Phenylephrine and Topamac 100 mg Tablet, you can take these medicines together if prescribed by your doctor. However, if you experience any unusual symptoms, consult the doctor. Do not discontinue any medications without consulting a doctor.
TopiramateAtropine
Severe
How does the drug interact with Topamac 100 mg Tablet:
When atropine and Topamac 100 mg Tablet are taken together it can cause increased body temperature and decreased sweating.

How to manage the interaction:
Although taking atropine and Topamac 100 mg Tablet together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience drowsiness, dizziness, or lightheadedness, or if you have reduced sweating or a fever, consult a doctor immediately. Avoid tasks that need mental attention, such as driving or operating dangerous machinery. Do not discontinue any medications without consulting a doctor.
TopiramateTriprolidine
Severe
How does the drug interact with Topamac 100 mg Tablet:
Combining Topamac 100 mg Tablet with Triprolidine can increase the risk of CNS depression.

How to manage the interaction:
Although there is a possible interaction between Triprolidine and Topamac 100 mg Tablet, you can take these medicines together if prescribed by your doctor. If you're having any of these symptoms like feeling too hot, feeling sleepy or dizzy, or having trouble thinking clearly, it's important to let your doctor know right away. They may be able to recommend different options for you that won't cause these problems. Do not discontinue any medications without first consulting your doctor.
TopiramateProcyclidine
Severe
How does the drug interact with Topamac 100 mg Tablet:
Coadministration of Topamac 100 mg Tablet with procyclidine causes increased body temperature and decreased sweating.

How to manage the interaction:
Although there is an interaction between procyclidine and Topamac 100 mg Tablet, they can be taken together if prescribed by your doctor. However, consult a doctor immediately if you experience drowsiness, dizziness, lightheadedness, or confusion. It is advised not to drive or use any hazardous machinery. Do not stop using any medications without a doctor's advice.
TopiramateTrihexyphenidyl
Severe
How does the drug interact with Topamac 100 mg Tablet:
Taking trihexyphenidyl with Topamac 100 mg Tablet can increase the risk of increase body temperature and reduced sweating.

How to manage the interaction:
Co-administration of Trihexyphenidyl with Topamac 100 mg Tablet can result in an interaction, but it can be taken if your doctor has advised it. However, if you experience dizziness or lightheaded, increase body temperature contact your doctor right away. Do not discontinue any medications without first consulting your doctor.
TopiramateCariprazine
Severe
How does the drug interact with Topamac 100 mg Tablet:
Topamac 100 mg Tablet can cause increased body temperature and decreased sweating, and these effects may be worsened when combined with cariprazine.

How to manage the interaction:
Although taking Cariprazine and Topamac 100 mg Tablet together can evidently cause an interaction, it can be taken if your doctor has suggested it. If you're having symptoms like not sweating enough, having a high body temperature, or feeling tired, dizzy, or lightheaded, it's important to contact a doctor. Do not stop using any medications without a doctor's advice.
TopiramateMetformin
Severe
How does the drug interact with Topamac 100 mg Tablet:
The combined use of Metformin with Topamac 100 mg Tablet may increase the risk of Lactic acidosis (excessive lactic acid production in the blood).

How to manage the interaction:
Coadministration Metformin with Topamac 100 mg Tablet can lead to an interaction, it can be taken if prescribed by a doctor. However, if you experience symptoms such as weakness, muscle pain, respiratory distress, consult the doctor immediately. Do not stop using any medication without a doctor's advice.
TopiramateDexchlorpheniramine
Severe
How does the drug interact with Topamac 100 mg Tablet:
Co-administration of dexchlorpheniramine with Topamac 100 mg Tablet can increase the risk of Topamac 100 mg Tablet side effects like increased body temperature and decreased sweating especially in warm weather.

How to manage the interaction:
Taking Dexchlorpheniramine with Topamac 100 mg Tablet together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience decreased sweating, fever, or drowsiness, contact your doctor immediately. Make sure to hydrate yourself during warm weather or after exercise. Do not discontinue any medications without consulting your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat a balanced diet that consists of good fats, proteins, carbohydrates, vegetables, and fruit which helps the body and brain to work properly and keep a person healthy and energetic.

  • Fatigue is one of the primary reasons that trigger seizures in the body, so sleeping properly can help in relaxing the brain.

  • One should avoid the consumption of alcohol as it can trigger seizures in patients. Even one or two glasses can trigger epilepsy and worsen the side effects of Topamac 100 mg Tablet .

  • Keep yourself happy and avoid taking emotional stress as stress causes seizures. Persons who maintain healthy stress levels have reported that they have responded well to the medicine.

Habit Forming

No

Therapeutic Class

ANTICONVULSANT

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Alcohol

Caution

Do not consume alcohol while taking Topamac 100 mg Tablet as alcohol can worsen the side effects of the Topamac 100 mg Tablet including sleepiness and dizziness

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Pregnancy

Unsafe

Topamac 100 mg Tablet is a Category D pregnancy drug. It is not recommended for use during pregnancy as it may cause an increase in the risk of the cleft lip that is a congenital disability in the unborn baby.

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Breast Feeding

Caution

Caution is advised when Topamac 100 mg Tablet is using in nursing mothers as this medicine may pass into breast milk.

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Driving

Caution

Some persons may continue to face unpredictable seizures even after taking Topamac 100 mg Tablet and this medicine also affects thinking and motor skills and may affect vision. So patients should take caution before engaging in any activity including driving or operating any machine.

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Liver

Caution

Topamac 100 mg Tablet should be used with caution in patients with liver disease as the dosage needs to be reduced in patients dealing with liver disease.

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Kidney

Caution

Topamac 100 mg Tablet should be used with caution in patients with kidney disease as the dosage needs to be reduced in patients dealing with kidney disease.

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Children

Safe if prescribed

Topamac 100 mg Tablet is safe to use in children above 2 years only if prescribed by the doctor.

FAQs

Topamac 100 mg Tablet is primarily indicated in the treatment of epilepsy (Monotherapy and Adjunctive therapy), and it can also be used to prevent migraine.

Seizures can happen when the brain cells are not working properly or working faster than normal. Topamac 100 mg Tablet slows down these electrical signals to stop seizures.

No, you should take rest after taking this medicine as this medicine affects the thinking ability and vision of a person so avoid doing any task that requires mental alertness.

Topamac 100 mg Tablet acts by decreasing the spread of seizure activity in the brain. It also restores the normal balance of neurons which in turn calms the brain. In epilepsy, cells present in the brain talk to each other by generating electric signals. When these cells fail to work properly or working faster than normal then it causes seizures. Topamac 100 mg Tablet slows down these electrical signals and thus prevents or controls seizures. While in migraine, Topamac 100 mg Tablet tranquilizes the overactive nerve cells in the brain that are responsible for causing migraine.

Yes, the use of Topamac 100 mg Tablet is safe for long time use if suggested by the doctor.

Country of origin

India

Manufacturer/Marketer address

Johnson & Johnson Private Limited., 501 Arena Space, Behind Majas Bus Depot, Off Jogeshwari Vikhroli Link Road, Jogeshwari (E), Mumbai 400 060
Other Info - TOP0001

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