Tonact Plus Tablet belongs to a class of medications called antilipemic (cholesterol-lowering agent). Tonact Plus Tablet is used to treat raised cholesterol levels in our body. Tonact Plus Tablet helps lower the level of low-density lipoprotein (LDL) or bad cholesterol in the blood and increases high-density lipoprotein (HDL) or good cholesterol. Dyslipidaemia is the deposition of unhealthy levels of fats (lipid) in the blood. In this condition, there is always a high level of low-density lipoprotein (LDL or bad cholesterol), triglycerides (TG), and a low level of high-density lipoprotein (HDL or good cholesterol). Tonact Plus Tablet is an extended-release formulation that releases slowly for a longer duration of time.

Tonact Plus Tablet contains two medicines, namely atorvastatin and nicotinic acid (vitamin B3). Atorvastatin is a lipid-lowering medication that blocks the enzyme required to make cholesterol in the body. It reduces the bad cholesterol (also known as low-density lipoproteins or LDL), triglycerides (TG) and increases the levels of good cholesterol (also known as high-density lipoproteins or HDL). On the other hand, Tonact Plus Tablet contains nicotinic acid, which is a form of vitamin B that further increases good cholesterol levels (HDL).

Take Tonact Plus Tablet as prescribed by your doctor. You are advised to take Tonact Plus Tablet for as long as your doctor has prescribed it for you, depending on your medical conditions. You may experience constipation, nausea, stomach pain, weakness, muscle pain, headache, dizziness, itching, flushing of the skin, the increased glucose level in the blood. Most of these side effects of Tonact Plus Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Do not take Tonact Plus Tablet if you are allergic to Tonact Plus Tablet , or any other ingredients present in it. Tonact Plus Tablet should not be taken in conditions like liver disease or kidney disease. Tonact Plus Tablet should not be prescribed to children less than 10 years of age. Immediately inform your doctor before taking Tonact Plus Tablet if you are pregnant or planning to get pregnant, breastfeeding. Tonact Plus Tablet has negligible influence on the ability to drive and use machines. Do not drink too much while taking this medicine.

Tonact Plus Tablet taken with dietary measures helps treat high cholesterol, especially for heart patients when initial dietary measures fail to lower cholesterol. It helps lower the bad cholesterol (LDL) and increases the level of good cholesterol (HDL) in the state of dyslipidemia or hyperlipidemia. Tonact Plus Tablet is considered more effective compared to other cholesterol-lowering medicines. Tonact Plus Tablet also lowers the amount of fat or cholesterol deposition (plaque) in the heart's arteries, thereby reducing the chance of having a heart attack or stroke in the future. Tonact Plus Tablet contains nicotinic acid, which is a form of vitamin B that further increases good cholesterol levels (HDL). 

• Constipation
• Nausea
• Stomach pain
• Weakness
• Muscle pain
• Abnormal heart rhythm
• Abnormal liver function tests
• Headache
• Arthralgia
• Dizziness
• Diarrhea
• Itching
• Peripheral Edema
• Flushing of skin
• Increased glucose level in the blood

Tonact Plus Tablet may cause a breakdown of skeletal muscle tissue, leading to kidney failure. This condition usually occurs in the elderly, people with kidney disease, and poorly controlled hypothyroidism (underactive thyroid). Tonact Plus Tablet should not be prescribed to children less than 10 years of age. You should contact a doctor before if you have had an allergic reaction to Tonact Plus Tablet , have a liver problem (jaundice, liver cirrhosis), or kidney problems, pregnant or planning to get pregnant, breastfeeding, have severe lung disease, have a previous heart attack or stroke caused by bleeding in the brain, have hypothyroidism, drink more than 2 servings of alcohol per day and have a muscle disorder (fibromyalgia) and damaged muscle tissue (rhabdomyolysis).

Drug-Drug Interaction: This medicine may interact with immunosuppressant medicines (cyclosporine), cholesterol-lowering medicines (gemfibrozil), antifungal (itraconazole), antiviral/HIV medicine (ritonavir), medicines for heart disease (digoxin), blood thinner (warfarin), anti-hypertensive drugs (like verapamil, diltiazem).

Drug-Food Interaction: Tonact Plus Tablet may interact with grapefruit. It increases the concentration of Tonact Plus Tablet in your body.

Drug-Disease Interaction: Patients with serious liver disease (jaundice), kidney disease, lung disease, thyroid disease, and muscle weakness (rhabdomyolysis) should be closely monitored while having treatment with Tonact Plus Tablet .

• CYCLOSPORINE
• GEMFIBROZIL
• ITRACONAZOLE
• RITONAVIR
• DIGOXIN
• WARFARIN
• VERAPAMIL
• DILTIAZEM

• Try aromatherapy, yoga, meditation to help relax your body and mind.
• Try to do breathing exercises to get more oxygen.
• Eat a healthy diet rich in soluble fiber like beans, legumes, whole grain, flax, apples, and citrus fruits.
• Try to replace most of your saturated fats with unsaturated fats that can reduce total cholesterol and LDL cholesterol in a short span of time. Foods like avocados, olive oil, fatty fish, and nuts contain many heart-healthy unsaturated fats, so it’s beneficial to eat them regularly.
• Try to adopt a Mediterranean-style diet rich in olive oil, fruits, vegetables, nuts, whole grains, fish, and low in red meat and most dairy.
• Try to give priority to more fruits and veggies in your daily meal as these contain antioxidants that help to lower LDL
• Minimize the intake of added sugar. The American Heart Association (ADA) recommends, one should not eat more than 100 calories (25 grams) of added sugar for women and children and no more than 150 calories (37.5 grams) for men every day.
• American Heart Association recommends sodium chloride intake (table salt) should not exceed more than 2,300 mg per day as part of a healthy eating pattern.
• As a precautionary measure, do not consume alcohol and quit smoking.

If muscle fatigue or muscle pain affects your daily activity. Try to contact a doctor if you have muscle weakness or fatigue.

High cholesterol: Cholesterol is a waxy substance produced by the liver to protect nerves, make tissue, and various hormones. Our body also receives cholesterol from the food we eat, like cooking oils, eggs, meats, and dairy products. Excess cholesterol is bad for our health. There are two types of cholesterol, namely 'bad cholesterol' and 'good cholesterol'. Bad cholesterol comprises low-density lipoprotein (LDL) and triglycerides (TG), while good cholesterol consists of high-density lipoprotein (HDL). Usually, there are no specific symptoms of raised or high cholesterol levels but a large deposition of cholesterol in the arteries (plaque) or heart blockage. Blocked artery or plaque formation in the heart's arteries can lead to chest pain (angina), heart attack, or stroke. It is advisable to have complete cholesterol tests (lipid profile test) at least once a year. It will help you to closely monitor your heart health and risk of heart attack and stroke.