Tolu-XR 4 Tablet is used for overactive bladder syndrome (it is a condition in which the bladder contracts muscles uncontrollably and urgent need to urinate, causing frequent urination and inability to control urination).

Tolu-XR 4 Tablet contains tolteradone. Tolu-XR 4 Tablet works by relaxing the urinary bladder muscles and prevents urgent, frequent, or uncontrolled urination.

Take Tolu-XR 4 Tablet as prescribed by your doctor. Depending on your medical conditions, you are advised to take Tolu-XR 4 Tablet for as long as your doctor has prescribed it for you. You may experience dryness in the mouth, headache, constipation, sleepiness, dizziness, blurred vision, and dry skin. Most of these side effects of Tolu-XR 4 Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Before starting Tolu-XR 4 Tablet , please inform your doctor if you have any allergies, glaucoma (increased pressure in the eye that may cause vision loss), urinary retention (inability to empty your bladder completely or at all), or gastric retention (slow emptying of your stomach). Do not take this Tolu-XR 4 Tablet if you have liver, kidney, heart problems or constipation. Immediately contact your doctor if you are pregnant and breastfeeding.

Tolu-XR 4 Tablet belongs to a group of medications known as antimuscarinics. Tolu-XR 4 Tablet is used for overactive bladder syndrome (it is a condition in which the bladder contracts muscles uncontrollably and urgent need to urinate, causing frequent urination and inability to control urination). Tolu-XR 4 Tablet works by relaxing the urinary bladder muscles and prevents urgent, frequent, or uncontrolled urination.

• Dryness in the mouth
• Headache
• Constipation
• Sleepiness
• Dizziness
• Blurred vision
• Dry skin

Do not take Tolu-XR 4 Tablet if you are allergic to Tolu-XR 4 Tablet  or any of its contents. Before taking Tolu-XR 4 Tablet , inform your doctor if you are pregnant or breastfeeding or have kidney disease, liver disease, bladder blockage, controlled narrow-angle glaucoma, or stomach or bowel problems (including constipation), or a history of heart rhythm problems (including QT prolongation), gastrointestinal disorders, and myasthenia gravis (a long-term neuromuscular disease that leads to varying degrees of skeletal muscle weakness). Tolu-XR 4 Tablet has lactose, so inform your doctor if you are intolerant to sugars. Tolu-XR 4 Tablet may cause dizziness or blurred vision. So, do not drive or operate any heavy machinery. It can increase body temperature by decreasing sweating. So, avoid hot weather or strenuous exercise as this may cause overheating, which may lead to unwanted effects.

Drug-Drug Interactions: Care should be exercised when Tolu-XR 4 Tablet is administered in combination with antibiotics (containing, e.g. erythromycin, clarithromycin), medicinal products used for the treatment of fungal infections (e.g. ketoconazole, itraconazole), medicinal products used for the treatment of HIV, medicines for the treatment of irregular heartbeat (containing, e.g. amiodarone, sotalol, quinidine, procainamide), and other medication with a similar mode of action to Tolu-XR 4 Tablet (antimuscarinic properties) or medicines with an opposite mode of action to Tolu-XR 4 Tablet (cholinergic properties).

Drug-Food Interactions: Avoid taking grapefruit juice and alcohol with this Tolu-XR 4 Tablet .

Drug-Disease Interactions: Tolu-XR 4 Tablet may interact with disease conditions, including glaucoma, liver, kidney problems, myasthenia gravis, gastrointestinal disorders, and heart-related diseases (e.g. QT Prolongation).

• ERYTHROMYCIN
• CLARITHROMYCIN
• KETOCONAZOLE
• ITRACONAZOLE
• AMIODARONE
• SOTALOL
• QUINIDINE
• PROCAINAMIDE

• Eat fresh fruits like pears, bananas, and citrus fruits, and green vegetables like beans and potatoes. 
• Try to take cranberry juice as it helps in minimizing urinary infections. 
• Avoid coffee, tea, and carbonated drinks which contain caffeine. 
• Do not consume processed, fried, or spicy foods, as these can irritate your bladder. 
• Limit alcohol intake as it can increase the risk of side effects.
• Quit smoking and exercise regularly.

• Intake of Tolu-XR 4 Tablet can make you sweat less, thereby increasing the chance of having a heat stroke in summer. So avoid doing tasks which may cause you to overheat.
• Intake of Tolu-XR 4 Tablet may occasionally cause blurry vision and dizziness, so avoid driving a motor vehicle, operating heavy machinery, and performing hazardous tasks requiring mental alertness.

Overactive bladder syndrome: Overactive bladder syndrome may lead to a common and sudden need to urinate that may be difficult to control. You may feel like you want to pass urine many times during the night and day and may also experience accidental loss of urine. Although it is common among older adults, an overactive bladder is not a normal part of ageing. It might not be easy to talk about your symptoms, but if they disturb you or interrupt your life, inform your doctor.