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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
TOLPERITAS-DSR TABLETS is used to reduce and relieve pain due to the muscle spasms (excessive tension in the muscles). It contains Diclofenac and Tolperisone, which work on the brain and spinal cord centres to relieve muscle stiffness or spasm and relieve pain and improve muscle's movement. Also, it reduces mild to moderate pain and inflammation. It may cause side effects such as nausea, diarrhoea, vomiting, heartburn, weakness, stomach pain/epigastric pain, sleepiness, dizziness, and appetite loss. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Manufacturer/Marketer :

Intas Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About TOLPERITAS-DSR TABLETS

TOLPERITAS-DSR TABLETS belongs to a class of medications called Non-steroidal anti-inflammatory drugs (NSAIDs) or pain killer. TOLPERITAS-DSR TABLETS is used to reduce and relieve pain due to the muscle spasms (excessive tension in the muscles). Muscle spasm is the sudden involuntary contractions of the muscle, which can be painful and uncomfortable. When the nerve impulses that control the muscle movements are damaged or interrupted, it could lead to muscle spasms.

TOLPERITAS-DSR TABLETS is a combination of two drugs, namely: Diclofenac and Tolperisone. Diclofenac is a pain killer (NSAIDs) while Tolperisone is a skeletal muscle relaxant. Diclofenac works by blocking the effect of a chemical messenger in your body, known as cyclo-oxygenase (COX) enzymes that make another chemical 'prostaglandins' (PG). These prostaglandins are produced at injury sites and cause pain and swelling. By blocking COX enzyme's effect, lesser PGs are produced, which reduces mild to moderate pain and inflammation at the injured or damaged site. On the other hand, Tolperisone works on the brain and spinal cord centres to relieve muscle stiffness or spasm and relieve pain and improve muscle's movement.

Take TOLPERITAS-DSR TABLETS as prescribed by your doctor. You are advised to take TOLPERITAS-DSR TABLETS for as long as your doctor has prescribed it for you depending on your medical conditions. You may experience nausea, diarrhoea, vomiting, heartburn, weakness, stomach pain/epigastric pain, sleepiness, dizziness, and appetite loss. Most of these side effects of TOLPERITAS-DSR TABLETS do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

TOLPERITAS-DSR TABLETS can increase your risk of fatal heart attack or stroke. So, if you have had any recent heart surgery, do not use TOLPERITAS-DSR TABLETS. TOLPERITAS-DSR TABLETS increases the chances of stomach ulcers and bleeding.  Before taking this TOLPERITAS-DSR TABLETS, inform your doctor if you have any allergies, myasthenia gravis (weakness in muscles), asthma, and hay fever. To treat your condition effectually, continue taking TOLPERITAS-DSR TABLETS for as long as your doctor has prescribed. Do not take TOLPERITAS-DSR TABLETS if you are pregnant or breastfeeding unless prescribed. TOLPERITAS-DSR TABLETS causes drowsiness and dizziness, so drive with caution. TOLPERITAS-DSR TABLETS should not be given to children as safety and efficacy have not been established. Avoid consuming alcohol along with TOLPERITAS-DSR TABLETS as it could lead to increased drowsiness and dizziness, it might also increase the risk of stomach bleeding. Keep your doctor informed about your health condition and medicines to rule out any side-effects.

Uses of TOLPERITAS-DSR TABLETS

Treatment of Pain due to muscle spasm.

Directions for Use

Swallow TOLPERITAS-DSR TABLETS as a whole with water; do not crush, break or chew it.

Medicinal Benefits

TOLPERITAS-DSR TABLETS belongs to a class of medications called Non-steroidal anti-inflammatory drugs (NSAIDs) or pain killers. TOLPERITAS-DSR TABLETS is a combination of two drugs, namely: Diclofenac and Tolperisone. Diclofenac is a pain killer (NSAIDs) while Tolperisone is a skeletal muscle relaxant. Diclofenac works by blocking the effect of a chemical messenger in your body, known as cyclo-oxygenase (COX) enzymes that make another chemical 'prostaglandins' (PG). These prostaglandins are produced at injury sites and cause pain and swelling. By blocking COX enzyme's effects, lesser PGs are produced, which reduces mild to moderate pain and inflammation at the injured or damaged site. On the other hand, Tolperisone works on the brain and spinal cord centres to relieve muscle stiffness or spasm and relieve pain and improve muscle's movement. Altogether TOLPERITAS-DSR TABLETS relieves pain and relaxes the muscles.

How TOLPERITAS-DSR TABLETS Works

TOLPERITAS-DSR TABLETS is a combination of two drugs, namely: Diclofenac and Tolperisone. Diclofenac is a pain killer (NSAIDs) while Tolperisone is a skeletal muscle relaxant. Diclofenac works by blocking the effect of a chemical messenger in your body, known as cyclo-oxygenase (COX) enzymes that make another chemical 'prostaglandins' (PG). These prostaglandins are produced at injury sites and cause pain and swelling. By blocking COX enzyme's effect, lesser PGs are produced, which reduces mild to moderate pain and inflammation at the injured or damaged site. On the other hand, Tolperisone works on the brain and spinal cord centres to relieve muscle stiffness or spasm and relieve pain and improve muscle's movement.

Storage

Store in a cool and dry place away from sunlight

Side Effects of TOLPERITAS-DSR TABLETS

  • Nausea
  • Diarrhoea
  • Vomiting
  • Loss of appetite
  • Heartburn
  • Weakness
  • Stomach pain/epigastric pain
  • Sleepiness
  • Dizziness
  • Numbness and tingling
  • Ringing in the ears

What if I have taken an overdose of TOLPERITAS-DSR TABLETS

Do not take more than the prescribed dose of TOLPERITAS-DSR TABLETS as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

TOLPERITAS-DSR TABLETS can increase your risk of fatal heart attack or stroke. So, if you have had any recent heart surgery, do not use TOLPERITAS-DSR TABLETS. Do not take TOLPERITAS-DSR TABLETS if you are allergic to TOLPERITAS-DSR TABLETS, have severe heart failure, have suffered bleeding problems such as bleeding from stomach or bowels while taking any pain killers or you have liver or kidney problems. Inform your doctor before taking TOLPERITAS-DSR TABLETS if you have or had high blood pressure, heart problems, high cholesterol, diabetes, asthma, liver and kidney problems. Do not take TOLPERITAS-DSR TABLETS if you are pregnant or breastfeeding unless prescribed. TOLPERITAS-DSR TABLETS causes drowsiness and dizziness, so drive only if you are alert. TOLPERITAS-DSR TABLETS should not be given to children as the safety have not been established. Avoid consuming alcohol and TOLPERITAS-DSR TABLETS as it could lead to increased drowsiness and increase the risk of stomach bleeding. Stop taking TOLPERITAS-DSR TABLETS and consult your doctor immediately if you have stomach pain or any signs of bleeding in intestine or stomach such as blood in stools. Do not take any other NSAID's for pain relief along with TOLPERITAS-DSR TABLETS unless prescribed. Keep your doctor informed about your health condition and medicines to rule out any side-effects.

Drug-Drug Interactions

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DiclofenacMeloxicam
Critical
DiclofenacSulindac
Severe

Drug-Drug Interactions

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DiclofenacMeloxicam
Critical
How does the drug interact with Tolperitas-DSR Tablet 5's:
Co-administration of Tolperitas-DSR Tablet 5's with Meloxicam can increase the risk or severity of gastrointestinal side effects.

How to manage the interaction:
Taking Meloxicam with Tolperitas-DSR Tablet 5's is not recommended as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, consult your doctor immediately if you experience symptoms such as dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness. Do not stop any medication without doctor's advise.
DiclofenacSulindac
Severe
How does the drug interact with Tolperitas-DSR Tablet 5's:
Co-administration of Tolperitas-DSR Tablet 5's and sulindac can increase the risk of side effects.

How to manage the interaction:
Although there is a interaction between Tolperitas-DSR Tablet 5's and sulindac, it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult your doctor immediately. Do not stop using any medications without a doctor's advice.
DiclofenacValdecoxib
Severe
How does the drug interact with Tolperitas-DSR Tablet 5's:
Taking Valdecoxib with Tolperitas-DSR Tablet 5's may increase risk of side effects.

How to manage the interaction:
There may be a possible interaction between Tolperitas-DSR Tablet 5's and Valdecoxib but can be taken if prescribed by doctor. However, consult your doctor immediately if you experience any unusual bleeding or bruising or have other signs and symptoms of bleeding such as dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness. Do not stop any medications without consulting a doctor.
DiclofenacCelecoxib
Severe
How does the drug interact with Tolperitas-DSR Tablet 5's:
Co-administration of Tolperitas-DSR Tablet 5's with Celecoxib may increase the risk of stomach bleeding and ulcers.

How to manage the interaction:
Although there is a interaction between Tolperitas-DSR Tablet 5's and Celecoxib, but it can be taken if your doctor has advised it. Consult a doctor if you experience symptoms like blood in your urine or stool (or a black stool), severe bruising, prolonged nosebleeds, feeling dizzy or lightheaded, weakness or severe headache, vomiting blood or coughing up blood, heavy menstrual bleeding (in women), difficulty breathing, or chest pain. Do not discontinue any medication without consulting a doctor.
DiclofenacEnoxaparin
Severe
How does the drug interact with Tolperitas-DSR Tablet 5's:
Taking Tolperitas-DSR Tablet 5's with Enoxaparin can increase the risk of bleeding complications.

How to manage the interaction:
There may be a possible interaction between Tolperitas-DSR Tablet 5's and Enoxaparin, but they can be taken together if your doctor has prescribed them. However, consult your doctor immediately if you experience any unusual bleeding or bruising, swelling, vomiting, blood in your urine or stools, headache, dizziness, or weakness. Do not discontinue any medications without consulting a doctor.
DiclofenacPanobinostat
Severe
How does the drug interact with Tolperitas-DSR Tablet 5's:
Taking Tolperitas-DSR Tablet 5's with Panobinostat can increase the risk of bleeding complications.

How to manage the interaction:
There may be a possible interaction between Tolperitas-DSR Tablet 5's and Panobinostat, but they can be taken together if your doctor has prescribed them. However, consult your doctor immediately if you experience any unusual bleeding or have other signs of bleeding like dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headaches. Do not discontinue any medications without consulting your doctor.
DiclofenacFondaparinux
Severe
How does the drug interact with Tolperitas-DSR Tablet 5's:
Coadministration of Tolperitas-DSR Tablet 5's with fondaparinux may increase the risk of bleeding.

How to manage the interaction:
There may be a possible interaction between Tolperitas-DSR Tablet 5's and Fondaparinux when taken together, but they can be taken together if your doctor has prescribed them. However, if you experience bleeding, severe back pain, dizziness, black or red stools, severe headache, weakness, and vomiting contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
DiclofenacTacrolimus
Severe
How does the drug interact with Tolperitas-DSR Tablet 5's:
Co-administration of Tolperitas-DSR Tablet 5's with tacrolimus may cause kidney problems.

How to manage the interaction:
Co-administration of Tolperitas-DSR Tablet 5's and Tacrolimus can lead to an interaction, it can be taken if advised by your doctor. However, consult your doctor if you experience nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not stop using any medications without a doctor's advice.
DiclofenacLeflunomide
Severe
How does the drug interact with Tolperitas-DSR Tablet 5's:
Co administration of Tolperitas-DSR Tablet 5's with Leflunomide may result in liver problems.

How to manage the interaction:
Co-administration of Tolperitas-DSR Tablet 5's and Leflunomide can lead to an interaction; it can be taken if advised by your doctor. However, if you have a fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark-colored urine, light-colored stools, or yellowing of the skin or eyes. Do not stop using any medication without consulting your doctor.
DiclofenacTolmetin
Severe
How does the drug interact with Tolperitas-DSR Tablet 5's:
Taking Tolperitas-DSR Tablet 5's with Tolmetin may increase the risk of side effects.

How to manage the interaction:
There may be a possible interaction between Tolperitas-DSR Tablet 5's and Tolmetin but can be taken if prescribed by doctor. However, consult your doctor immediately if you experience any unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness. Do not stop any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Exercising regularly helps in muscle stretching so that they are less likely to spasm, tear and sprain. Mild exercises such as jogging and walking are helpful for muscle stretching.
  • Massages can also be helpful.
  • Avoid freezing and hot temperatures.
  • Avoid wearing tight-fitting clothes, instead, wear loose garments.
  • Rest well, get plenty of sleep.
  • To avoid developing pressure sores, change your position at least every two hours.
  • Hot or cold therapy can help treat muscle spasms. Apply an ice-pack or hot-pack on the muscle for 15-20minutes.
  • Stay hydrated, drink plenty of water.

Habit Forming

No

Therapeutic Class

ANALGESICS

TOLPERITAS-DSR TABLETS Substitute

Substitutes safety advice
  • Myotop-DSR Tablet 5's

    43.84per tablet
  • TEXXA D TABLET 5S

    28.68per tablet
  • Toltris DSR Tablet

    35.91per tablet
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Alcohol

Unsafe

Avoid consumption of alcohol while taking TOLPERITAS-DSR TABLETS as it may increase dizziness. It can also increase the risk of stomach bleeding.

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Pregnancy

Caution

Avoid taking TOLPERITAS-DSR TABLETS if you are pregnant unless prescribed by a doctor. Please consult your doctor if you have any concerns regarding this, your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Unsafe

TOLPERITAS-DSR TABLETS must not be used during breastfeeding.

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Driving

Caution

TOLPERITAS-DSR TABLETS may cause sleepiness or dizziness. Do not drive or do anything needing concentration until you know how it affects you.

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Liver

Unsafe

Those who have severe liver problems should not take this TOLPERITAS-DSR TABLETS because TOLPERITAS-DSR TABLETS contains Tolperisone, which causes the most dangerous adverse in patients with liver disease.

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Kidney

Unsafe

Those who have severe kidney problems should not take this TOLPERITAS-DSR TABLETS because TOLPERITAS-DSR TABLETS contains Tolperisone, which causes the most dangerous adverse in patients with kidney disease.

bannner image

Children

Unsafe

TOLPERITAS-DSR TABLETS should not be given to children as the safety and effectiveness were not established.

FAQs

TOLPERITAS-DSR TABLETS is used to reduce and relieve pain due to the muscle spasms (excessive tension in the muscles).
TOLPERITAS-DSR TABLETS is a combination of two drugs: Diclofenac (Nonsteroidal Anti-Inflammatory Drug) and metaxalone (skeletal muscle relaxant). Diclofenac works by blocking the action of certain chemical messengers that cause pain. Tolperisone works on the spinal cord and centres in the brain to relieve contraction or muscle stiffness without decreasing strength.
TOLPERITAS-DSR TABLETS may impair mental and/or physical abilities required for the performance of heavy tasks like operating machinery or driving a motor vehicle, especially when used with alcohol.
Do not take TOLPERITAS-DSR TABLETS for longer durations as it might increase the risk of heart problems, liver problems and stomach bleeding/ulcer. Please consult a doctor before its use.
There are no recognized reports of any patient getting addicted to TOLPERITAS-DSR TABLETS.
If you are suffering from muscle pain due to overuse or muscle injury, you should take rest. Taking rest will help you to prevent any further injury and help you improve effectively. Make sure that you take enough sleep and try to decrease stress. Applying an ice pack to the altered area may help in reducing inflammation and pain. If your muscle pain is due to some other illness, follow the guidance of your doctor.
Take a missed dose as soon as you remember it. If it is close to the time for your next dose, skip the missed dose and go back to your regular time. Do not take 2 doses at the same time or extra doses.

Country of origin

India

Manufacturer/Marketer address

Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.
Other Info - TOL0181

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