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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Tolifast-D Tablet is used to reduce and relieve pain due to the muscle spasms (excessive tension in the muscles). It contains Diclofenac and Tolperisone, which work on the brain and spinal cord centres to relieve muscle stiffness or spasm and relieve pain and improve muscle's movement. Also, it reduces mild to moderate pain and inflammation. It may cause side effects such as nausea, diarrhoea, vomiting, heartburn, weakness, stomach pain/epigastric pain, sleepiness, dizziness, and appetite loss. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Manufacturer/Marketer :

Lupin Ltd

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Tolifast-D Tablet

Tolifast-D Tablet belongs to a class of medications called Non-steroidal anti-inflammatory drugs (NSAIDs) or pain killer. Tolifast-D Tablet is used to reduce and relieve pain due to the muscle spasms (excessive tension in the muscles). Muscle spasm is the sudden involuntary contractions of the muscle, which can be painful and uncomfortable. When the nerve impulses that control the muscle movements are damaged or interrupted, it could lead to muscle spasms.

Tolifast-D Tablet is a combination of two drugs, namely: Diclofenac and Tolperisone. Diclofenac is a pain killer (NSAIDs) while Tolperisone is a skeletal muscle relaxant. Diclofenac works by blocking the effect of a chemical messenger in your body, known as cyclo-oxygenase (COX) enzymes that make another chemical 'prostaglandins' (PG). These prostaglandins are produced at injury sites and cause pain and swelling. By blocking COX enzyme's effect, lesser PGs are produced, which reduces mild to moderate pain and inflammation at the injured or damaged site. On the other hand, Tolperisone works on the brain and spinal cord centres to relieve muscle stiffness or spasm and relieve pain and improve muscle's movement.

Take Tolifast-D Tablet as prescribed by your doctor. You are advised to take Tolifast-D Tablet for as long as your doctor has prescribed it for you depending on your medical conditions. You may experience nausea, diarrhoea, vomiting, heartburn, weakness, stomach pain/epigastric pain, sleepiness, dizziness, and appetite loss. Most of these side effects of Tolifast-D Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Tolifast-D Tablet can increase your risk of fatal heart attack or stroke. So, if you have had any recent heart surgery, do not use Tolifast-D Tablet . Tolifast-D Tablet increases the chances of stomach ulcers and bleeding.  Before taking this Tolifast-D Tablet , inform your doctor if you have any allergies, myasthenia gravis (weakness in muscles), asthma, and hay fever. To treat your condition effectually, continue taking Tolifast-D Tablet for as long as your doctor has prescribed. Do not take Tolifast-D Tablet if you are pregnant or breastfeeding unless prescribed. Tolifast-D Tablet causes drowsiness and dizziness, so drive with caution. Tolifast-D Tablet should not be given to children as safety and efficacy have not been established. Avoid consuming alcohol along with Tolifast-D Tablet as it could lead to increased drowsiness and dizziness, it might also increase the risk of stomach bleeding. Keep your doctor informed about your health condition and medicines to rule out any side-effects.

Uses of Tolifast-D Tablet

Treatment of Pain due to muscle spasm.

Directions for Use

Swallow Tolifast-D Tablet as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Tolifast-D Tablet belongs to a class of medications called Non-steroidal anti-inflammatory drugs (NSAIDs) or pain killers. Tolifast-D Tablet is a combination of two drugs, namely: Diclofenac and Tolperisone. Diclofenac is a pain killer (NSAIDs) while Tolperisone is a skeletal muscle relaxant. Diclofenac works by blocking the effect of a chemical messenger in your body, known as cyclo-oxygenase (COX) enzymes that make another chemical 'prostaglandins' (PG). These prostaglandins are produced at injury sites and cause pain and swelling. By blocking COX enzyme's effects, lesser PGs are produced, which reduces mild to moderate pain and inflammation at the injured or damaged site. On the other hand, Tolperisone works on the brain and spinal cord centres to relieve muscle stiffness or spasm and relieve pain and improve muscle's movement. Altogether Tolifast-D Tablet  relieves pain and relaxes the muscles.

How Tolifast-D Tablet Works

Tolifast-D Tablet is a combination of two drugs, namely: Diclofenac and Tolperisone. Diclofenac is a pain killer (NSAIDs) while Tolperisone is a skeletal muscle relaxant. Diclofenac works by blocking the effect of a chemical messenger in your body, known as cyclo-oxygenase (COX) enzymes that make another chemical 'prostaglandins' (PG). These prostaglandins are produced at injury sites and cause pain and swelling. By blocking COX enzyme's effect, lesser PGs are produced, which reduces mild to moderate pain and inflammation at the injured or damaged site. On the other hand, Tolperisone works on the brain and spinal cord centres to relieve muscle stiffness or spasm and relieve pain and improve muscle's movement.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Tolifast-D Tablet

  • Nausea
  • Diarrhoea
  • Vomiting
  • Loss of appetite
  • Heartburn
  • Weakness
  • Stomach pain/epigastric pain
  • Sleepiness
  • Dizziness
  • Numbness and tingling
  • Ringing in the ears

What if I have taken an overdose of Tolifast-D Tablet

Do not take more than the prescribed dose of Tolifast-D Tablet as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

Tolifast-D Tablet can increase your risk of fatal heart attack or stroke. So, if you have had any recent heart surgery, do not use Tolifast-D Tablet . Do not take Tolifast-D Tablet if you are allergic to Tolifast-D Tablet , have severe heart failure, have suffered bleeding problems such as bleeding from stomach or bowels while taking any pain killers or you have liver or kidney problems. Inform your doctor before taking Tolifast-D Tablet if you have or had high blood pressure, heart problems, high cholesterol, diabetes, asthma, liver and kidney problems. Do not take Tolifast-D Tablet if you are pregnant or breastfeeding unless prescribed. Tolifast-D Tablet causes drowsiness and dizziness, so drive only if you are alert. Tolifast-D Tablet should not be given to children as the safety have not been established. Avoid consuming alcohol and Tolifast-D Tablet as it could lead to increased drowsiness and increase the risk of stomach bleeding. Stop taking Tolifast-D Tablet and consult your doctor immediately if you have stomach pain or any signs of bleeding in intestine or stomach such as blood in stools. Do not take any other NSAID's for pain relief along with Tolifast-D Tablet unless prescribed. Keep your doctor informed about your health condition and medicines to rule out any side-effects.

Drug-Drug Interactions

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DiclofenacMeloxicam
Critical
DiclofenacBromfenac
Severe

Drug-Drug Interactions

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DiclofenacMeloxicam
Critical
How does the drug interact with Tolifast-D Tablet 10's:
Co-administration of Tolifast-D Tablet 10's with Meloxicam can increase the risk or severity of gastrointestinal side effects.

How to manage the interaction:
Taking Meloxicam with Tolifast-D Tablet 10's is not recommended as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, consult your doctor immediately if you experience symptoms such as dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness. Do not stop any medication without doctor's advise.
DiclofenacBromfenac
Severe
How does the drug interact with Tolifast-D Tablet 10's:
Taking Tolifast-D Tablet 10's with bromfenac will have an additive effect and may increase the risk of side effects in the gastrointestinal tract such as inflammation, bleeding, ulceration, and rarely, perforation.

How to manage the interaction:
There may be possible interaction between Tolifast-D Tablet 10's and bromfenac but you can take it if prescribed by a doctor. Consult your doctor if you experience any unusual bleeding or bruising or have other signs and symptoms of bleeding such as dizziness; lightheadedness; red or black, tarry stools; coughing up or vomiting fresh or dried blood that looks like coffee grounds; severe headache; and weakness. Do not stop using any medications without first talking to your doctor.
DiclofenacCelecoxib
Severe
How does the drug interact with Tolifast-D Tablet 10's:
Co-administration of Tolifast-D Tablet 10's with Celecoxib may increase the risk of stomach bleeding and ulcers.

How to manage the interaction:
Although there is a interaction between Tolifast-D Tablet 10's and Celecoxib, but it can be taken if your doctor has advised it. Consult a doctor if you experience symptoms like blood in your urine or stool (or a black stool), severe bruising, prolonged nosebleeds, feeling dizzy or lightheaded, weakness or severe headache, vomiting blood or coughing up blood, heavy menstrual bleeding (in women), difficulty breathing, or chest pain. Do not discontinue any medication without consulting a doctor.
DiclofenacFondaparinux
Severe
How does the drug interact with Tolifast-D Tablet 10's:
Coadministration of Tolifast-D Tablet 10's with fondaparinux may increase the risk of bleeding.

How to manage the interaction:
There may be a possible interaction between Tolifast-D Tablet 10's and Fondaparinux when taken together, but they can be taken together if your doctor has prescribed them. However, if you experience bleeding, severe back pain, dizziness, black or red stools, severe headache, weakness, and vomiting contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
DiclofenacDasatinib
Severe
How does the drug interact with Tolifast-D Tablet 10's:
Taking Dasatinib together with Tolifast-D Tablet 10's may increase the risk of bleeding.

How to manage the interaction:
There may be a possible interaction between Tolifast-D Tablet 10's and Dasatinib but they can be taken together if a doctor has prescribed them. However, consult a doctor immediately if you experience dizziness, red or black, tarry stools, or severe headaches. Do not discontinue any medications without consulting a doctor.
DiclofenacMipomersen
Severe
How does the drug interact with Tolifast-D Tablet 10's:
Co-administration of Tolifast-D Tablet 10's with Mipomersen may cause liver problems.

How to manage the interaction:
Co-administration of Tolifast-D Tablet 10's and Mipomersen can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of hunger, fatigue, nausea, vomiting, abdominal pain, dark urine, pale stools, and/or yellowing of the skin or eyes. Do not discontinue any medications without consulting a doctor.
DiclofenacTolmetin
Severe
How does the drug interact with Tolifast-D Tablet 10's:
Taking Tolifast-D Tablet 10's with Tolmetin may increase the risk of side effects.

How to manage the interaction:
There may be a possible interaction between Tolifast-D Tablet 10's and Tolmetin but can be taken if prescribed by doctor. However, consult your doctor immediately if you experience any unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness. Do not stop any medications without consulting a doctor.
DiclofenacPanobinostat
Severe
How does the drug interact with Tolifast-D Tablet 10's:
Taking Tolifast-D Tablet 10's with Panobinostat can increase the risk of bleeding complications.

How to manage the interaction:
There may be a possible interaction between Tolifast-D Tablet 10's and Panobinostat, but they can be taken together if your doctor has prescribed them. However, consult your doctor immediately if you experience any unusual bleeding or have other signs of bleeding like dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headaches. Do not discontinue any medications without consulting your doctor.
DiclofenacDeferasirox
Severe
How does the drug interact with Tolifast-D Tablet 10's:
Co-administration of Tolifast-D Tablet 10's and deferasirox may increase your risk of developing stomach bleeding.

How to manage the interaction:
There may be a possible interaction between Tolifast-D Tablet 10's and deferasirox but they can be taken together if your doctor has prescribed them. However, consult your doctor immediately if you experience symptoms such as severe abdominal pain, bloating, sudden dizziness or lightheadedness, nausea, vomiting (especially with blood), loss of appetite, and/or black, tarry stools, increased or decreased urination, fluid retention, swelling, shortness of breath, muscle cramps, weakness, confusion, and irregular heart rhythm. Do not stop using any medications without first talking to your doctor.
DiclofenacKetorolac
Severe
How does the drug interact with Tolifast-D Tablet 10's:
Co-administration of Tolifast-D Tablet 10's and Ketorolac can increase the risk of side effects.

How to manage the interaction:
Co-administration of Tolifast-D Tablet 10's and Ketorolac can lead to an interaction; it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult your doctor immediately. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Exercising regularly helps in muscle stretching so that they are less likely to spasm, tear and sprain. Mild exercises such as jogging and walking are helpful for muscle stretching.
  • Massages can also be helpful.
  • Avoid freezing and hot temperatures.
  • Avoid wearing tight-fitting clothes, instead, wear loose garments.
  • Rest well, get plenty of sleep.
  • To avoid developing pressure sores, change your position at least every two hours.
  • Hot or cold therapy can help treat muscle spasms. Apply an ice-pack or hot-pack on the muscle for 15-20minutes.
  • Stay hydrated, drink plenty of water.

Habit Forming

No

Therapeutic Class

ANALGESICS

Tolifast-D Tablet Substitute

Substitutes safety advice
  • Tolperitas D Tablet 10's

    23.67per tablet
  • Tolkem D Tablet 10's

    by AYUR

    19.35per tablet
  • Myotop-D Tablet 10's

    17.91per tablet
  • Toperizone D Tablet 10's

    by AYUR

    19.44per tablet
  • Tolmenta-D Tablet 10's

    by AYUR

    21.56per tablet
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Alcohol

Unsafe

Avoid consumption of alcohol while taking Tolifast-D Tablet as it may increase dizziness. It can also increase the risk of stomach bleeding.

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Pregnancy

Caution

Avoid taking Tolifast-D Tablet if you are pregnant unless prescribed by a doctor. Please consult your doctor if you have any concerns regarding this, your doctor will prescribe only if the benefits outweigh the risks.

bannner image

Breast Feeding

Unsafe

Tolifast-D Tablet must not be used during breastfeeding.

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Driving

Caution

Tolifast-D Tablet may cause sleepiness or dizziness. Do not drive or do anything needing concentration until you know how it affects you.

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Liver

Unsafe

Those who have severe liver problems should not take this Tolifast-D Tablet because Tolifast-D Tablet contains Tolperisone, which causes the most dangerous adverse in patients with liver disease.

bannner image

Kidney

Unsafe

Those who have severe kidney problems should not take this Tolifast-D Tablet because Tolifast-D Tablet contains Tolperisone, which causes the most dangerous adverse in patients with kidney disease.

bannner image

Children

Unsafe

Tolifast-D Tablet should not be given to children as the safety and effectiveness were not established.

FAQs

Tolifast-D Tablet is used to reduce and relieve pain due to the muscle spasms (excessive tension in the muscles).
Tolifast-D Tablet is a combination of two drugs: Diclofenac (Nonsteroidal Anti-Inflammatory Drug) and metaxalone (skeletal muscle relaxant). Diclofenac works by blocking the action of certain chemical messengers that cause pain. Tolperisone works on the spinal cord and centres in the brain to relieve contraction or muscle stiffness without decreasing strength.
Tolifast-D Tablet may impair mental and/or physical abilities required for the performance of heavy tasks like operating machinery or driving a motor vehicle, especially when used with alcohol.
Do not take Tolifast-D Tablet for longer durations as it might increase the risk of heart problems, liver problems and stomach bleeding/ulcer. Please consult a doctor before its use.
There are no recognized reports of any patient getting addicted to Tolifast-D Tablet .
If you are suffering from muscle pain due to overuse or muscle injury, you should take rest. Taking rest will help you to prevent any further injury and help you improve effectively. Make sure that you take enough sleep and try to decrease stress. Applying an ice pack to the altered area may help in reducing inflammation and pain. If your muscle pain is due to some other illness, follow the guidance of your doctor.
Take a missed dose as soon as you remember it. If it is close to the time for your next dose, skip the missed dose and go back to your regular time. Do not take 2 doses at the same time or extra doses.

Country of origin

India

Manufacturer/Marketer address

Lupin Ltd, 3rd floor Kalpataru Inspire, Off. W E Highway, Santacruz (East), Mumbai 400 055. India Country of Origin: India
Other Info - TOL0093

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