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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Tolaz LA 405mg/vial Convenience Kit is used to treat schizophrenia and bipolar I disorder. It contains 'Olanzapine' that works by restoring the balance of chemical messengers in the brain and improving thinking, mood, and behaviour. It improves mental clarity and lessens hallucinations. It is used to treat schizophrenia-related agitation and the manic phases of bipolar disorder. Common side effects of Tolaz LA 405mg/vial Convenience Kit are drowsiness, dizziness, headache, dry mouth, nausea, vomiting, diarrhoea, constipation, stomach pain, back pain, runny/stuffy nose, cough, increased appetite, weight gain, redness/pain/swelling at the injection site.
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Composition :

OLANZAPINE-405MG

Manufacturer/Marketer :

Torrent Pharmaceuticals Ltd

Consume Type :

PARENTERAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Tolaz LA 405mg/vial Convenience Kit

Tolaz LA 405mg/vial Convenience Kit belongs to a group of medicines called 'atypical antipsychotics,' primarily used to treat schizophrenia and manic or mixed episodes of bipolar I disorder. Schizophrenia is a mental condition in which you may feel, hear or see things that are not there (hallucinations), believe things that are not true, and feel unusually suspicious or confused. Bipolar I disorder is a serious brain disorder where you experience extreme mood swings (variance in thinking) and frequent mood and behaviour changes.

Tolaz LA 405mg/vial Convenience Kit contains 'Olanzapine' that works by restoring the balance of chemical messengers in the brain and improves thinking mood, and behaviour. Tolaz LA 405mg/vial Convenience Kit improves mental clarity and lessens hallucinations. It is used to treat schizophrenia-related agitation and the manic phases of bipolar disorder.

Tolaz LA 405mg/vial Convenience Kit will be administered by a health care professional; do not self-administer. Common side effects include drowsiness, dizziness, headache, dry mouth, nausea, vomiting, diarrhoea, constipation, stomach pain, back pain, runny/stuffy nose, cough, increased appetite, weight gain, and redness/pain/swelling at the injection site. These side effects are not common for everyone. If you notice any side effects that are not manageable, please consult your doctor. 

Tolaz LA 405mg/vial Convenience Kit is not recommended for treatment in patients with Dementia-Related Psychosis. Inform your doctor beforehand if you have a history of allergic reactions to Olanzapine, Alzheimer's disease, liver or kidney diseases, heart problems, breathing problems, high cholesterol, glaucoma, diabetes, breast cancer, enlarged prostate, and fits before taking this medicine. If you are pregnant, planning to conceive, or breastfeeding, inform your doctor before receiving Tolaz LA 405mg/vial Convenience Kit. Avoid consuming alcohol along with Tolaz LA 405mg/vial Convenience Kit as it can make you dizzy or drowsy. Do not drive or operate machinery after using Tolaz LA 405mg/vial Convenience Kit since it can make you sleepy. Olanzapine is not recommended for children and adolescents below 18 years of age; however, please seek medical advice.

Uses of Tolaz LA 405mg/vial Convenience Kit

Treatment of Schizophrenia and bipolar I disorder

Directions for Use

It will be administered by a healthcare professional; do not self-administer.

Medicinal Benefits

Tolaz LA 405mg/vial Convenience Kit is used to treat manic episodes of bipolar I disorder and agitation in schizophrenia. It contains 'Olanzapine,' which belongs to the class of atypical antipsychotics. It works by restoring the balance of chemical messengers in the brain. It is also known to improve thinking, mood, and behaviour. It helps in clear thinking and relieves psychotic symptoms like hallucinations.

How Tolaz LA 405mg/vial Convenience Kit Works

Tolaz LA 405mg/vial Convenience Kit contains 'Olanzapine' that works by restoring the balance of chemical messengers in the brain and improves thinking mood, and behaviour. Tolaz LA 405mg/vial Convenience Kit improves mental clarity and lessens hallucinations. It is used to treat schizophrenia-related agitation and the manic phases of bipolar disorder.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Tolaz LA 405mg/vial Convenience Kit

  • Drowsiness
  • Dizziness
  • Headache 
  • Dry mouth
  • Nausea
  • Vomiting
  • Diarrhoea
  • Constipation
  • Stomach pain
  • Back pain
  • Runny/stuffy nose
  • Cough
  • Increased appetite
  • Weight gain
  • Redness/pain/swelling at the injection site

What if I have taken an overdose of Tolaz LA 405mg/vial Convenience Kit

Since Tolaz LA 405mg/vial Convenience Kit is given in a controlled medical setting by a healthcare professional, an overdose is not likely to occur. If you think there has been an overdose or experiencing any adverse events, get medical care right away. In a medical setting, an overdose would be treated quickly. Overdose of Tolaz LA 405mg/vial Convenience Kit may cause agitation, aggressive behaviour, Confusion, dizziness, disorientation, difficulty walking, slurred speech, slowed or uncontrollable movements, muscle stiffness, weakness, seizures, fast heartbeat, drowsiness, and coma (loss of consciousness for a period of time).

Drug Warnings

Tolaz LA 405mg/vial Convenience Kit is not recommended for use in patients with Dementia-Related Psychosis. Brief your medical history to the doctor if you have any allergic reactions, liver or kidney diseases, Alzheimer's disease, dementia, heart problems, breathing problems, high cholesterol, glaucoma, diabetes, bowel problems, sleep apnea, low white blood cell count, breast cancer, enlarged prostate, or fits before starting Tolaz LA 405mg/vial Convenience Kit. Please inform your doctor if you are pregnant or planning to conceive before starting this medicine. Tolaz LA 405mg/vial Convenience Kit is not recommended during breastfeeding. Avoid consuming alcohol as it might lead to increased side effects like dizziness and drowsiness. Avoid driving or operating machinery as Tolaz LA 405mg/vial Convenience Kit may decrease your mental alertness, making you feel dizzy or drowsy. Tolaz LA 405mg/vial Convenience Kit is not recommended for people below 18 years of age as safety and effectiveness have not been established.

Drug-Drug Interactions

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OlanzapinePotassium chloride
Critical
OlanzapinePramipexole
Critical

Drug-Drug Interactions

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OlanzapinePotassium chloride
Critical
How does the drug interact with Tolaz LA 405mg/vial Convenience Kit 1's:
Taking Tolaz LA 405mg/vial Convenience Kit 1's with Potassium chloride can increase the risk of stomach ulcers, bleeding, and gastrointestinal injury.

How to manage the interaction:
Co-administration of Tolaz LA 405mg/vial Convenience Kit 1's and Potassium chloride is not recommended as it leads to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like severe abdominal pain, bloating, sudden dizziness or lightheadedness, nausea, vomiting (especially with blood), loss of appetite, and/or black, tarry stools, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
OlanzapinePramipexole
Critical
How does the drug interact with Tolaz LA 405mg/vial Convenience Kit 1's:
Taking Tolaz LA 405mg/vial Convenience Kit 1's with Pramipexole can increase the risk and severity of side effects and reduce the effectiveness of Pramipexole.

How to manage the interaction:
Co-administration of Tolaz LA 405mg/vial Convenience Kit 1's and Pramipexole is not recommended as it leads to an interaction, it can be taken if advised by a doctor. If you experience any symptoms such as drowsiness, dizziness, and lightheadedness, contact a doctor immediately. Avoid driving or operating dangerous machinery, and be careful while getting up from a sitting or lying position. Do not discontinue any medications without consulting a doctor.
OlanzapineRopinirole
Critical
How does the drug interact with Tolaz LA 405mg/vial Convenience Kit 1's:
When Ropinirole is taken with Tolaz LA 405mg/vial Convenience Kit 1's, it may reduce the effectiveness of ropinirole.

How to manage the interaction:
Taking Ropinirole with Tolaz LA 405mg/vial Convenience Kit 1's is not recommended as it can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as drowsiness, low blood pressure, dizziness, and lightheadedness. Do not stop using any medications without consulting doctor.
OlanzapinePotassium citrate
Critical
How does the drug interact with Tolaz LA 405mg/vial Convenience Kit 1's:
Taking Tolaz LA 405mg/vial Convenience Kit 1's with Potassium citrate can increase the irritant effects of potassium on your stomach and upper intestine.

How to manage the interaction:
Co-administration of Tolaz LA 405mg/vial Convenience Kit 1's and Potassium citrate is not recommended as it leads to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like severe abdominal pain, bloating, sudden dizziness or lightheadedness, nausea, vomiting (especially with blood), loss of appetite, and/or black, tarry stools, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
OlanzapineOndansetron
Severe
How does the drug interact with Tolaz LA 405mg/vial Convenience Kit 1's:
The combined use of Ondansetron and Tolaz LA 405mg/vial Convenience Kit 1's can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Co-administration of Ondansetron and Tolaz LA 405mg/vial Convenience Kit 1's can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, heart palpitations, diarrhea, or vomiting, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
OlanzapinePentazocine
Severe
How does the drug interact with Tolaz LA 405mg/vial Convenience Kit 1's:
Combining Tolaz LA 405mg/vial Convenience Kit 1's with Pentazocine can cause central nervous system depression such as Tolaz LA 405mg/vial Convenience Kit 1's can lead to serious side effects including respiratory distress, intestinal obstruction, fecal impaction.

How to manage the interaction:
Although taking Tolaz LA 405mg/vial Convenience Kit 1's and Pentazocine together can lead to an interaction, it can be taken if your doctor has suggested it. If you experience any symptoms like feeling tired, having trouble breathing, feeling dizzy or drowsy, difficulty focusing, taking pain or cough medications, constipation, blockage in your intestines, difficulty passing stool, hard or dry stool, less frequent bowel movements, stomach problems, feeling sick, feeling bloated, having stomach pain, or swelling contact the doctor immediately. you should avoid driving or operating hazardous machinery until you know how they affect you and do not discontinue any medications without consulting your doctor.
OlanzapineHydrocodone
Severe
How does the drug interact with Tolaz LA 405mg/vial Convenience Kit 1's:
Combining Tolaz LA 405mg/vial Convenience Kit 1's with Hydrocodone can cause central nervous system depression such as Tolaz LA 405mg/vial Convenience Kit 1's can lead to serious side effects including respiratory distress, intestinal obstruction, fecal impaction.

How to manage the interaction:
Although taking Tolaz LA 405mg/vial Convenience Kit 1's and Hydrocodone together can lead to an interaction, it can be taken if your doctor has suggested it. If you experience any symptoms like feeling tired, having trouble breathing, feeling dizzy or drowsy, difficulty focusing, taking pain or cough medications, constipation, blockage in your intestines, difficulty passing stool, hard or dry stool, less frequent bowel movements, stomach problems, feeling sick, feeling bloated, having stomach pain, or swelling contact the doctor immediately. you should avoid driving or operating hazardous machinery until you know how they affect you and do not discontinue any medications without consulting your doctor.
OlanzapineChlordiazepoxide
Severe
How does the drug interact with Tolaz LA 405mg/vial Convenience Kit 1's:
Co-administration of Tolaz LA 405mg/vial Convenience Kit 1's with chlordiazepoxide may significantly increase the occurrence side effects.

How to manage the interaction:
Taking Tolaz LA 405mg/vial Convenience Kit 1's and chlordiazepoxide together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience any symptoms such as low blood pressure, rapid breathing, weak pulse, muscle weakness, drowsiness, dizziness, or slurred speech, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
OlanzapineTopiramate
Severe
How does the drug interact with Tolaz LA 405mg/vial Convenience Kit 1's:
Combining Tolaz LA 405mg/vial Convenience Kit 1's with Topiramate can increase the risk of overheating and reduced sweating.

How to manage the interaction:
Taking Tolaz LA 405mg/vial Convenience Kit 1's with Topiramate together can possibly result in an interaction, but it can be taken if your doctor has advised it. If you have any symptoms like decreased sweating, fever, drowsiness, dizziness, or lightheadedness consult the doctor immediately. Avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medications affect you and do not discontinue any medications without consulting your doctor.
OlanzapineKetamine
Severe
How does the drug interact with Tolaz LA 405mg/vial Convenience Kit 1's:
Using ketamine together with Tolaz LA 405mg/vial Convenience Kit 1's may increase side effects such as dizziness, drowsiness, confusion, difficulty concentrating, excessive sedation, and respiratory depression, impairment in thinking, judgment, and motor coordination.

How to manage the interaction:
Co-administration of ketamine of Tolaz LA 405mg/vial Convenience Kit 1's can lead to an interaction, it can be taken if advised by your doctor. If you experience any symptoms, contact your doctor immediately. Avoid alcohol and activities requiring mental alertness such as driving, operating hazardous machinery, or engaging in potentially hazardous activities until you know how the medications affect you. Do not discontinue any medications without consulting your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Maintain proper weight by following a healthy diet.
  • Exercise regularly as it helps in less cognitive decline and brain volume loss.
  • Avoid smoking and alcohol consumption.
  • Try to avoid stress by practising meditation or yoga.
  • Include fruits and vegetables in your diet as they contain antioxidants.
  • Eat nutritious food as it helps in cognitive stimulation.
  • Limit foods with high cholesterol and saturated fats.
  • Cut down on sugar, salt and processed foods.
  • Drink plenty of water.
  • Follow a healthy lifestyle as it helps in improving overall health and possibly protects the brain.

Habit Forming

No

Therapeutic Class

ANTIPSYCHOTICS
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Alcohol

Unsafe

Avoid alcohol consumption while taking Tolaz LA 405mg/vial Convenience Kit as it may cause increased dizziness and drowsiness.

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Pregnancy

Caution

Olanzapine is a pregnancy category C drug. Using antipsychotic drugs during the third trimester of pregnancy may cause muscle problems in newborn babies. There are no adequate and well-controlled studies on pregnant women. Please inform your doctor before taking Tolaz LA 405mg/vial Convenience Kit if you are pregnant or planning pregnancy. Your doctor will weigh the potential risks and benefits before prescribing Tolaz LA 405mg/vial Convenience Kit.

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Breast Feeding

Unsafe

Olanzapine is excreted into the breast milk; hence it is not recommended for a nursing mother. Please inform your doctor before using Tolaz LA 405mg/vial Convenience Kit if you are a breastfeeding mother.

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Driving

Unsafe

Tolaz LA 405mg/vial Convenience Kit may make you feel dizzy or drowsy. Do not drive or operate machinery if you are not mentally alert or experience any symptoms that affect your ability to concentrate.

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Liver

Caution

Tolaz LA 405mg/vial Convenience Kit should not be used in case of Hepatitis (including hepatocellular, cholestatic or mixed liver injury). If you have a history of liver disease, inform your doctor before receiving Tolaz LA 405mg/vial Convenience Kit. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Kidney

Caution

If you have a history of kidney disease, inform your doctor before receiving Tolaz LA 405mg/vial Convenience Kit. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Children

Unsafe

Tolaz LA 405mg/vial Convenience Kit is not indicated for use in treating children and adolescents below 18 years of age. Please seek medical advice.

FAQs

Tolaz LA 405mg/vial Convenience Kit is used to treat Schizophrenia and bipolar I disorder.
Tolaz LA 405mg/vial Convenience Kit contains Olanzapine, an antipsychotic that balances the chemical messengers in the brain, improving mood, behaviour and thoughts.
Tolaz LA 405mg/vial Convenience Kit should be used with caution in the medical history of allergic reactions, liver or kidney diseases, heart problems, Alzheimer's disease, high cholesterol, glaucoma, diabetes, stomach/intestinal problems, breathing problem during sleep (sleep apnea), low white blood cell count, breast cancer, enlarged prostate, or fits. Please let your doctor know if you have any other medical history before starting the treatment with Tolaz LA 405mg/vial Convenience Kit.
Tolaz LA 405mg/vial Convenience Kit may make you sweat less and can likely cause a heart stroke. Hence, limiting activities that cause overheating, like an exercise in hot weather or using hot tubs, is advised. Drink plenty of fluids and dress lightly.
Tolaz LA 405mg/vial Convenience Kit may cause dizziness. It is advised to avoid getting up too fast from a sitting or lying position that can make you feel dizzy.
Olanzapine can cause side effects like orthostatic hypotension (sudden lowering in blood pressure leading to dizziness on standing). If you experience this, do not try to stand up suddenly or start walking; instead, lie down and get up slowly only when you feel better. This medicine should be cautiously advised in people with cardiovascular and cerebrovascular diseases. Patients taking Tolaz LA 405mg/vial Convenience Kit are advised to regularly monitor their blood pressure levels to avoid any unpleasant events. It is also advised to be aware of a condition called tardive dyskinesia (uncontrolled movements of the face, lips, mouth, tongue, arms or legs) that may rarely occur while using this medicine.

Country of origin

India

Manufacturer/Marketer address

Off. Ashram Road, Ahmedabad - 380 009., Gujarat, India
Other Info - TOL0116

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