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Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Tolaz DT 5 Tablet is an antipsychotic medicine used in the treatment of schizophrenia and bipolar disorder. This medication helps to improve mood, behavior, and thoughts by preventing the effects of dopamine and serotonin, two chemical messengers in the brain. Common side effects include drowsiness, dizziness, restlessness, tremors/shakiness, stomach upset, dry mouth, constipation, increased appetite, fatigue, and weight gain.
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Composition :

OLANZAPINE-5MG

Manufacturer/Marketer :

Torrent Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

Tolaz DT 5 Tablet is used to treat schizophrenia and manic depression (bipolar disorder). Schizophrenia is a mental condition in which the person may feel, hear or see things that are not there (hallucinations), believe things that are not true, and feel unusually suspicious or confused. Manic depression, or bipolar disorder, is a serious brain disorder in which a person experiences extreme mood swings (variance in thinking) and frequent mood and behavioural changes.

Tolaz DT 5 Tablet contains 'Olanzapine' that works by restoring the balance of chemical messengers (dopamine and serotonin) in the brain and improves thinking mood, and behaviour. It helps in clear thinking and decreases hallucinations. It is used for treating manic episodes of bipolar disorder and agitation in schizophrenia.

Take Tolaz DT 5 Tablet as prescribed by your doctor. Common side effects include drowsiness, dizziness, restlessness, tremors/shakiness, stomach upset, dry mouth, constipation, increased appetite, fatigue, decreased libido, swelling of the hands or feet, and weight gain. These side effects are not familiar to everyone and vary individually. If you notice any side effects that are not manageable, please consult your doctor.

Tolaz DT 5 Tablet is not recommended for treatment in patients with Dementia-Related Psychosis. Inform your doctor beforehand if you have a history of allergic reactions to Olanzapine, Alzheimer's disease, liver or kidney diseases, heart problems, breathing problems, high cholesterol, glaucoma, diabetes, breast cancer, enlarged prostate, or fits before starting this medicine. If you are pregnant, planning to conceive, or a breastfeeding mother, inform your doctor before starting Tolaz DT 5 Tablet . Avoid consuming alcohol while being treated with Tolaz DT 5 Tablet as it can make you dizzy or drowsy. Do not drive or operate machinery while using Tolaz DT 5 Tablet since it can make you sleepy. This medicine is not recommended for children below 12 years of age.

Treatment of Schizophrenia and Manic depression (bipolar disorder)
Tablet/Capsule: Swallow it as a whole with a glass of water. Do not crush, chew or break it. Melt-in-mouth tablets/Fast Dissolving tablets/Tablet MD: Do not touch these tablets with wet hands. These tablets dissolve rapidly when placed on the tongue. Take the tablet and place it on your tongue. Let it disperse/dissolve in your oral cavity, and swallow it. There is no need to take these tablets with water.

Tolaz DT 5 Tablet is used to treat schizophrenia and manic depression (bipolar disorder). It effectively treats manic episodes of bipolar disorder and agitation in schizophrenia. It contains 'Olanzapine,' which belongs to the class of atypical antipsychotics. It works by restoring the balance of chemical messengers (dopamine and serotonin) in the brain. It is also known to improve thinking, mood, and behaviour. It helps in clear thinking and relieves psychotic symptoms like hallucinations.

Tolaz DT 5 Tablet contains 'Olanzapine' that works by restoring the balance of chemical messengers (dopamine and serotonin) in the brain and improves thinking mood, and behaviour. It helps in clear thinking and decreases hallucinations. It is used for treating manic episodes of bipolar disorder and agitation in schizophrenia.
Store in a cool and dry place away from sunlight
  • Drowsiness
  • Dizziness
  • Restlessness
  • Tremors/shakiness
  • Stomach upset
  • Dry mouth
  • Constipation
  • Increased appetite
  • Fatigue
  • Decreased libido
  • Swelling of the hands or feet
  • Weight gain
Avoid exceeding the recommended dose as it could lead to an overdose. Symptoms of overdose may include drowsiness, slurred speech, agitation, fast heartbeat, uncontrolled sudden movements, and coma. If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention.

Tolaz DT 5 Tablet is not recommended for treatment in patients with Dementia-Related Psychosis. Brief your medical history to the doctor if you have any allergic reactions, liver or kidney diseases, Alzheimer's disease, dementia, heart problems, breathing problems, high cholesterol, glaucoma, diabetes, bowel problems, breathing problem during sleep (sleep apnea), low white blood cell count, breast cancer, enlarged prostate, or fits before starting Tolaz DT 5 Tablet . Please consult your doctor if you are pregnant or planning to conceive before starting this medicine. Tolaz DT 5 Tablet is not recommended during breastfeeding. Avoid consuming alcohol as it might lead to increased side effects like dizziness and drowsiness. Avoid driving or operating machinery as Tolaz DT 5 Tablet may decrease your mental alertness, making you feel dizzy or drowsy. Tolaz DT 5 Tablet is not recommended for people below 12 years of age as safety and effectiveness have not been established.

verifiedApollotooltip
OlanzapinePramipexole
Critical
OlanzapineRopinirole
Critical

Drug-Drug Interactions

OlanzapinePramipexole
Critical
How does the drug interact with Tolaz DT 5 Tablet 15's:
Taking Tolaz DT 5 Tablet 15's with Pramipexole can increase the risk and severity of side effects and reduce the effectiveness of Pramipexole.

How to manage the interaction:
Co-administration of Tolaz DT 5 Tablet 15's and Pramipexole is not recommended as it leads to an interaction, it can be taken if advised by a doctor. If you experience any symptoms such as drowsiness, dizziness, and lightheadedness, contact a doctor immediately. Avoid driving or operating dangerous machinery, and be careful while getting up from a sitting or lying position. Do not discontinue any medications without consulting a doctor.
OlanzapineRopinirole
Critical
How does the drug interact with Tolaz DT 5 Tablet 15's:
When Ropinirole is taken with Tolaz DT 5 Tablet 15's, it may reduce the effectiveness of ropinirole.

How to manage the interaction:
Taking Ropinirole with Tolaz DT 5 Tablet 15's is not recommended as it can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as drowsiness, low blood pressure, dizziness, and lightheadedness. Do not stop using any medications without consulting doctor.
OlanzapinePotassium chloride
Critical
How does the drug interact with Tolaz DT 5 Tablet 15's:
Taking Tolaz DT 5 Tablet 15's with Potassium chloride can increase the risk of stomach ulcers, bleeding, and gastrointestinal injury.

How to manage the interaction:
Co-administration of Tolaz DT 5 Tablet 15's and Potassium chloride is not recommended as it leads to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like severe abdominal pain, bloating, sudden dizziness or lightheadedness, nausea, vomiting (especially with blood), loss of appetite, and/or black, tarry stools, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
OlanzapinePotassium citrate
Critical
How does the drug interact with Tolaz DT 5 Tablet 15's:
Taking Tolaz DT 5 Tablet 15's with Potassium citrate can increase the irritant effects of potassium on your stomach and upper intestine.

How to manage the interaction:
Co-administration of Tolaz DT 5 Tablet 15's and Potassium citrate is not recommended as it leads to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like severe abdominal pain, bloating, sudden dizziness or lightheadedness, nausea, vomiting (especially with blood), loss of appetite, and/or black, tarry stools, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
OlanzapinePentazocine
Severe
How does the drug interact with Tolaz DT 5 Tablet 15's:
Combining Tolaz DT 5 Tablet 15's with Pentazocine can cause central nervous system depression such as Tolaz DT 5 Tablet 15's can lead to serious side effects including respiratory distress, intestinal obstruction, fecal impaction.

How to manage the interaction:
Although taking Tolaz DT 5 Tablet 15's and Pentazocine together can lead to an interaction, it can be taken if your doctor has suggested it. If you experience any symptoms like feeling tired, having trouble breathing, feeling dizzy or drowsy, difficulty focusing, taking pain or cough medications, constipation, blockage in your intestines, difficulty passing stool, hard or dry stool, less frequent bowel movements, stomach problems, feeling sick, feeling bloated, having stomach pain, or swelling contact the doctor immediately. you should avoid driving or operating hazardous machinery until you know how they affect you and do not discontinue any medications without consulting your doctor.
OlanzapineOndansetron
Severe
How does the drug interact with Tolaz DT 5 Tablet 15's:
The combined use of Ondansetron and Tolaz DT 5 Tablet 15's can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Co-administration of Ondansetron and Tolaz DT 5 Tablet 15's can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, heart palpitations, diarrhea, or vomiting, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
OlanzapineMidazolam
Severe
How does the drug interact with Tolaz DT 5 Tablet 15's:
When used together, Midazolam and Tolaz DT 5 Tablet 15's can cause low blood pressure, shallow breathing, weak pulse, muscle weakness, drowsiness, dizziness and slurred speech.

How to manage the interaction:
Combining of Tolaz DT 5 Tablet 15's and Midazolam can lead to an interaction, it can be taken if your doctor has suggested it. If you experience any symptoms consult the doctor immediately. Avoid activities requiring mental alertness until you know how these medications will affect you and do not discontinue any medications without consulting a doctor.
OlanzapineHydrocodone
Severe
How does the drug interact with Tolaz DT 5 Tablet 15's:
Combining Tolaz DT 5 Tablet 15's with Hydrocodone can cause central nervous system depression such as Tolaz DT 5 Tablet 15's can lead to serious side effects including respiratory distress, intestinal obstruction, fecal impaction.

How to manage the interaction:
Although taking Tolaz DT 5 Tablet 15's and Hydrocodone together can lead to an interaction, it can be taken if your doctor has suggested it. If you experience any symptoms like feeling tired, having trouble breathing, feeling dizzy or drowsy, difficulty focusing, taking pain or cough medications, constipation, blockage in your intestines, difficulty passing stool, hard or dry stool, less frequent bowel movements, stomach problems, feeling sick, feeling bloated, having stomach pain, or swelling contact the doctor immediately. you should avoid driving or operating hazardous machinery until you know how they affect you and do not discontinue any medications without consulting your doctor.
OlanzapineKetamine
Severe
How does the drug interact with Tolaz DT 5 Tablet 15's:
Using ketamine together with Tolaz DT 5 Tablet 15's may increase side effects such as dizziness, drowsiness, confusion, difficulty concentrating, excessive sedation, and respiratory depression, impairment in thinking, judgment, and motor coordination.

How to manage the interaction:
Co-administration of ketamine of Tolaz DT 5 Tablet 15's can lead to an interaction, it can be taken if advised by your doctor. If you experience any symptoms, contact your doctor immediately. Avoid alcohol and activities requiring mental alertness such as driving, operating hazardous machinery, or engaging in potentially hazardous activities until you know how the medications affect you. Do not discontinue any medications without consulting your doctor.
OlanzapineNalbuphine
Severe
How does the drug interact with Tolaz DT 5 Tablet 15's:
Combining Tolaz DT 5 Tablet 15's with Nalbuphine can cause central nervous system depression such as Tolaz DT 5 Tablet 15's can lead to serious side effects including respiratory distress, intestinal obstruction, fecal impaction.

How to manage the interaction:
Although taking Tolaz DT 5 Tablet 15's and Nalbuphine together can lead to an interaction, it can be taken if your doctor has suggested it. If you experience any symptoms like feeling tired, having trouble breathing, feeling dizzy or drowsy, difficulty focusing, taking pain or cough medications, constipation, blockage in your intestines, difficulty passing stool, hard or dry stool, less frequent bowel movements, stomach problems, feeling sick, feeling bloated, having stomach pain, or swelling contact the doctor immediately. you should avoid driving or operating hazardous machinery until you know how they affect you and do not discontinue any medications without consulting your doctor.
verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

  • Maintain proper weight by following a healthy diet.

  • Exercise regularly as it helps in less cognitive decline and brain volume loss.

  • Avoid smoking and alcohol consumption.

  • Try to avoid stress by practising meditation or yoga.

  • Include fruits and vegetables in your diet as they contain antioxidants.

  • Eat nutritious food as it helps in cognitive stimulation.

  • Limit foods with high cholesterol and saturated fats.

  • Cut down on sugar, salt and processed foods.

  • Drink plenty of water.

  • Follow a healthy lifestyle as it helps in improving overall health and possibly protects the brain.

No
ANTIPSYCHOTICS

Tolaz DT 5 Tablet Substitute

Substitutes safety advice
  • Oleanz 5 Tablet 10's

    5.31per tablet
  • Olimelt 5mg Tablet 10's

    5.45per tablet
  • Olan-5 Tablet 10's

    3.61per tablet
  • Oleanz RT 5 Tablet 10's

    5.04per tablet
  • Oliza 5 Tablet 10's

    5.45per tablet
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FAQs

Tolaz DT 5 Tablet is used to treat schizophrenia and manic depression (bipolar disorder).
Tolaz DT 5 Tablet is used to treat schizophrenia and manic depression (bipolar disorder).
Tolaz DT 5 Tablet contains Olanzapine which works by balancing the chemical messengers like dopamine and serotonin located in the brain, improving mood, behaviour and thoughts.
Tolaz DT 5 Tablet should be used with caution in the medical history of allergic reactions, liver or kidney diseases, heart problems, breathing problems, Alzheimer's disease, high cholesterol, glaucoma, diabetes, stomach/intestinal problems, breathing problem during sleep (sleep apnea), low white blood cell count, breast cancer, enlarged prostate, or fits. Please let your doctor know if you have any other medical problems before starting Tolaz DT 5 Tablet .
Tolaz DT 5 Tablet may make you sweat less and can likely cause heart stroke. Hence, limiting activities that cause overheating, like an exercise in hot weather or using hot tubs, is advised. Drink plenty of fluids and dress lightly.
Tolaz DT 5 Tablet may cause dizziness. It is advised to avoid getting up too fast from a sitting or lying position that can make you feel dizzy.
Olanzapine can cause side effects like orthostatic hypotension (sudden lowering in blood pressure leading to dizziness on standing). If you experience this, do not try to stand up suddenly or start walking; instead, lie down and get up slowly only when you feel better. People taking Tolaz DT 5 Tablet are advised to regularly monitor their blood pressure levels to avoid such unpleasant events. It is also advised to be aware of a condition called tardive dyskinesia (uncontrolled movements of the face, lips, mouth, tongue, arms or legs) that may rarely occur while using this medicine.
No, Tolaz DT 5 Tablet is not a sleeping aid. It's an antipsychotic medication used to treat bipolar disorder and schizophrenia, not insomnia. If you need help with sleep, consult your healthcare provider or pharmacist for appropriate guidance and treatment.
Tolaz DT 5 Tablet is an antipsychotic medication that takes time to start working. It may take several weeks (typically 4-6 weeks or longer) to notice significant symptom improvements. Be patient and consistent with your medication regimen, and schedule regular follow-ups with your healthcare provider to monitor progress and adjust the treatment plan as needed. They will help you determine the effectiveness of the medication and make any necessary adjustments.
Do not stop taking Tolaz DT 5 Tablet suddenly; otherwise, your symptoms may return. If you need to stop taking olanzapine, your doctor will help you come off it by gradually reducing your dose. This will help prevent withdrawal symptoms.
There are no adequate and well-controlled studies on pregnant women. Please inform your doctor before taking Tolaz DT 5 Tablet if you are pregnant or planning pregnancy. Your doctor will weigh the potential risks and benefits before prescribing Tolaz DT 5 Tablet .
Tolaz DT 5 Tablet is not indicated for treating children and adolescents below 18. Please seek medical advice.
Tolaz DT 5 Tablet may cause dizziness or drowsiness. To ensure your safety, avoid driving or operating machinery if you're not mentally alert or experiencing symptoms that affect your concentration.
Yes, many people take Tolaz DT 5 Tablet for a long time, including for several months or years, without any problems. However, it's important to remember that you should only take Tolaz DT 5 Tablet as your healthcare provider prescribes. Regular monitoring and follow-up appointments with your healthcare provider are crucial to ensure the medication's safety and effectiveness. Your healthcare provider may also adjust your dosage or switch you to a different medication if needed.
When you start taking olanzapine, you may feel more relaxed and calmer. Within 2-3 weeks, you may notice improvements in your symptoms. Olanzapine can help you focus and think more clearly, stay on top of tasks, remember things more easily, connect with others, and distinguish between reality and delusions. It may also reduce or stop hearing voices.
Avoid drinking alcohol while taking olanzapine, especially during the initial treatment phase. Alcohol can exacerbate the medication's side effects, making you feel drowsy and unsteady. Excessive or daily alcohol consumption can worsen your symptoms and reduce the effectiveness of olanzapine. To ensure your safety and the medication's efficacy, it's best to abstain from alcohol or consult your healthcare provider for guidance.
Tolaz DT 5 Tablet is not typically used to treat anxiety, although some research has explored its potential in this area. It has not been approved for anxiety treatment, and your doctor will usually prescribe other medications as a first-line treatment for anxiety; however, if you're experiencing anxiety in conjunction with another condition that olanzapine is approved to treat, such as bipolar disorder or schizophrenia. In that case, your doctor may consider it part of your overall treatment plan."
The common side effects of the Tolaz DT 5 Tablet are nausea, vomiting, diarrhea, constipation, sores in the mouth and throat, pain, burning, or tingling in the hands or feet, pain, itching, redness, swelling, blisters, or sores in the place where the medication was injected, hair loss, pain, weakness, loss in ability to taste food. However, these symptoms vanish as your body adjusts to the medication. If these symptoms become worse, please consult a doctor for relief.
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