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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
Tofocom 200 mg/300 mg Tablet belongs to the class of antiretroviral drugs used in the treatment of HIV infection. This combination medicine work by inhibiting the reverse transcriptase enzyme production, which is necessary for the multiplication of the viruses. Common side effects include dizziness, headache, diarrhoea, nausea, vomiting, rashes, and feeling weak
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Manufacturer/Marketer :

Alkem Laboratories Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

About Tofocom 200 mg/300 mg Tablet

Tofocom 200 mg/300 mg Tablet belongs to a group of antiretroviral medicines used to treat HIV infection. Tofocom 200 mg/300 mg Tablet helps decrease the chance of developing AIDS (acquired immunodeficiency syndrome) and other HIV-related illnesses. Tofocom 200 mg/300 mg Tablet also helps reduce the risk of getting HIV-1 infection when used as a daily treatment and practising safe sex.

Tofocom 200 mg/300 mg Tablet is a combination of two drugs: Emtricitabine and Tenofovir disoproxil fumarate. Emtricitabine is a nucleoside reverse transcriptase inhibitor, whereas Tenofovir disoproxil fumarate is a nucleotide reverse transcriptase inhibitor. Tofocom 200 mg/300 mg Tablet works by interfering with the working of nucleotide and nucleoside reverse transcriptase enzymes necessary for virus reproduction. Together, Tofocom 200 mg/300 mg Tablet helps in treating HIV infection.

Take Tofocom 200 mg/300 mg Tablet as prescribed. Depending on your medical condition, you are advised to take Tofocom 200 mg/300 mg Tablet for as long as your doctor has prescribed it for you. Sometimes, you may experience certain common side effects such as headache, dizziness, nausea, vomiting, diarrhoea, weakness, and rash. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Practise safe sex and take necessary precautions, as Tofocom 200 mg/300 mg Tablet does not prevent the spread of HIV infection. Consult your doctor if you are pregnant or planning for pregnancy. Avoid breastfeeding while taking Tofocom 200 mg/300 mg Tablet. Tofocom 200 mg/300 mg Tablet may cause dizziness, so drive with caution. Tofocom 200 mg/300 mg Tablet is not recommended for children below 12 years. Keep your doctor informed about your health condition and medicines to prevent side effects/interactions.

Uses of Tofocom 200 mg/300 mg Tablet

Treatment of HIV infection

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Tofocom 200 mg/300 mg Tablet belongs to a group of antiretroviral medicines used to treat HIV infection. Tofocom 200 mg/300 mg Tablet helps in decreasing the chance of developing AIDS (acquired immunodeficiency syndrome) and other HIV-related illnesses. Tofocom 200 mg/300 mg Tablet is a combination of two drugs: Emtricitabine and Tenofovir disoproxil fumarate. Emtricitabine is a nucleoside reverse transcriptase inhibitor, whereas Tenofovir disoproxil fumarate is a nucleotide reverse transcriptase inhibitor. Tofocom 200 mg/300 mg Tablet works by interfering with the working of nucleotide and nucleoside reverse transcriptase enzymes which are necessary for the reproduction of the virus. Together, Tofocom 200 mg/300 mg Tablet helps in treating HIV infection. Taking Tofocom 200 mg/300 mg Tablet along with practising safe sex and lifestyle changes may reduce the risk of getting or transmitting the HIV virus to others.

How Tofocom 200 mg/300 mg Tablet Works

Tofocom 200 mg/300 mg Tablet is a combination of two drugs: Emtricitabine and Tenofovir disoproxil fumarate. Emtricitabine is a nucleoside reverse transcriptase inhibitor, whereas Tenofovir disoproxil fumarate is a nucleotide reverse transcriptase inhibitor. Tofocom 200 mg/300 mg Tablet works by interfering with the working of nucleotide and nucleoside reverse transcriptase enzymes necessary for virus reproduction. Together, Tofocom 200 mg/300 mg Tablet helps in treating HIV infection.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Tofocom 200 mg/300 mg Tablet

  • Headache
  • Dizziness
  • Nausea
  • Vomiting
  • Diarrhoea
  • Weakness
  • Rash

What if I have taken an overdose of Tofocom 200 mg/300 mg Tablet

Never take more than the prescribed dose of Tofocom 200 mg/300 mg Tablet. If you experience any of the following symptoms: clay-colored stools, dark urine, headache, fever, itching, nausea, vomiting, skin rash, stomach pain or tenderness, swelling of the lower legs or feet, unusual weakness or tiredness, yellow eyes or skin, or any combination of these, get medical attention right away.

Drug Warnings

Do not take Tofocom 200 mg/300 mg Tablet if you are allergic to any of its contents. Inform your doctor if you have a history of hepatitis B infection, kidney or liver problems; if you are older than 65years. Regularly get blood and urine tests done while taking Tofocom 200 mg/300 mg Tablet. Practise safe sex and take other necessary precautions as Tofocom 200 mg/300 mg Tablet does not prevent the spread of HIV infection. Consult your doctor if you are pregnant or planning for pregnancy. Avoid breastfeeding while taking Tofocom 200 mg/300 mg Tablet. Tofocom 200 mg/300 mg Tablet may cause dizziness, so drive with caution. Tofocom 200 mg/300 mg Tablet is not recommended for children below 12years. Talk to your doctor immediately if you notice any signs or symptoms of infection or inflammation.

Drug-Drug Interactions

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Tenofovir disoproxilStreptozocin
Critical
Tenofovir disoproxilDidanosine
Critical

Drug-Drug Interactions

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Tenofovir disoproxilStreptozocin
Critical
How does the drug interact with Tofocom 200 mg/300 mg Tablet:
Combining Tofocom 200 mg/300 mg Tablet and Streptozocin can increase the risk of kidney problems.

How to manage the interaction:
Taking Tofocom 200 mg/300 mg Tablet with Streptozocin is not recommended, as it can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not stop using any medications without talking to your doctor.
Tenofovir disoproxilDidanosine
Critical
How does the drug interact with Tofocom 200 mg/300 mg Tablet:
Coadministration of Didanosine with Tofocom 200 mg/300 mg Tablet can increase the levels and risk of Didanosine side effects.

How to manage the interaction:
Taking Didanosine with Tofocom 200 mg/300 mg Tablet is not recommended, please consult your doctor before taking it. It can be taken if your doctor prescribes it. However, if you experience severe headaches, confusion, weakness, trouble walking, muscle pain, or high fever, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
EmtricitabineLamivudine
Critical
How does the drug interact with Tofocom 200 mg/300 mg Tablet:
Combining these two medications may reduce overall effectiveness due to potential antagonistic effects (opposite actions).

How to manage the interaction:
Taking Tofocom 200 mg/300 mg Tablet with Lamivudine is not recommended, but it can be taken if your doctor prescribes it. Contact your doctor if your symptoms do not improve. Do not stop taking any medication without consulting your doctor.
Tenofovir disoproxilTobramycin
Severe
How does the drug interact with Tofocom 200 mg/300 mg Tablet:
Coadministration of tobramycin with Tofocom 200 mg/300 mg Tablet can increase the risk of kidney problems.

How to manage the interaction:
Taking Tofocom 200 mg/300 mg Tablet with Tobramycin together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm, contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
Tenofovir disoproxilFlurbiprofen
Severe
How does the drug interact with Tofocom 200 mg/300 mg Tablet:
Co-administration of Flurbiprofen with Tofocom 200 mg/300 mg Tablet can increase the risk of kidney problems.

How to manage the interaction:
Co-administration of Flurbiprofen with Tofocom 200 mg/300 mg Tablet can possibly result in an interaction, but it can be taken if prescribed by a doctor. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm contact your doctor immediately. Do not stop using any medications without consulting your doctor.
Tenofovir disoproxilBacitracin
Severe
How does the drug interact with Tofocom 200 mg/300 mg Tablet:
Coadministration of Bacitracin with Tofocom 200 mg/300 mg Tablet can increase the risk of developing kidney damage and reduced function.

How to manage the interaction:
Although there may be a possibility of interaction between Tofocom 200 mg/300 mg Tablet and Bacitracin, it can be taken when prescribed by a doctor. If you experience any symptoms, contact the doctor immediately. Do not stop using any medications without talking to your doctor.
Tenofovir disoproxilSulfasalazine
Severe
How does the drug interact with Tofocom 200 mg/300 mg Tablet:
Coadministration of Sulfasalazine and Tofocom 200 mg/300 mg Tablet can increase the risk of kidney problems.

How to manage the interaction:
Taking Sulfasalazine and Tofocom 200 mg/300 mg Tablet together can lead to an interaction, but it can be taken if your doctor advises. However, if you experience any symptoms like nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm, contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
Tenofovir disoproxilKetoprofen
Severe
How does the drug interact with Tofocom 200 mg/300 mg Tablet:
Coadministration of Ketoprofen and Tofocom 200 mg/300 mg Tablet can increase the risk of developing kidney problems.

How to manage the interaction:
Taking Ketoprofen and Tofocom 200 mg/300 mg Tablet together can lead to an interaction, but it can be taken if your doctor advises. However, if you experience any symptoms like nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, shortness of breath, muscle cramps, dizziness, and irregular heart rhythm, contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
Tenofovir disoproxilNeomycin
Severe
How does the drug interact with Tofocom 200 mg/300 mg Tablet:
Coadministration of Neomycin and Tofocom 200 mg/300 mg Tablet can increase the risk of developing kidney problems.

How to manage the interaction:
Taking Neomycin and Tofocom 200 mg/300 mg Tablet together can lead to an interaction, but it can be taken if your doctor advises. However, if you experience any symptoms like vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, shortness of breath, muscle cramps, dizziness, and irregular heart rhythm, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
Tenofovir disoproxilPhenobarbital
Severe
How does the drug interact with Tofocom 200 mg/300 mg Tablet:
Coadministration of Phenobarbital and Tofocom 200 mg/300 mg Tablet can reduce the levels of Tofocom 200 mg/300 mg Tablet, which can lead to low treatment outcomes.

How to manage the interaction:
Taking Tofocom 200 mg/300 mg Tablet with Phenobarbital can result in an interaction, it can be taken when a doctor has advised it. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  •  
  • Practise safe sex by using condoms; it helps in reducing contact with semen and vaginal fluids.
  • Never share personal items with body fluids or blood on them, such as razor blades or toothbrushes.
  • Avoid sharing used needles, other injections or drug equipment.
  • Get tested for other sexually transmitted infections such as gonorrhoea or syphilis, as they can make you prone to HIV infection.
  • Eat a healthy and balanced diet. Eat vitamin and nutrient-rich food such as vegetables and fruits as it helps to boost your immune system. Opt for lean protein and whole grains.
  • Avoid eating raw meat and eggs. Consume properly boiled and cooked meat, poultry or seafood.
  • Eat bland and low-fat foods and avoid spicy or oily foods if you experience nausea or vomiting.
  • Try to reduce emotional and physical stress by spending time with family or doing whatever makes you happy.
  •  

Habit Forming

No

Therapeutic Class

ANTIRETROVIRAL AGENTS

Tofocom 200 mg/300 mg Tablet Substitute

Substitutes safety advice
  • Tenvir-EM Tablet 30's

    80.03per tablet
  • Ricovir Em Capsule 30'S

    by AYUR

    67.65per tablet
  • Myvajra Tablet

    74.97per tablet
  • Emfovir Tablet

    58.50per tablet
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Alcohol

Caution

It is not known whether Tofocom 200 mg/300 mg Tablet interacts with alcohol. Please consult your doctor.

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Pregnancy

Caution

Please consult your doctor if you have any concerns regarding this, your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Unsafe

Avoid breastfeeding while taking Tofocom 200 mg/300 mg Tablet as it may pass into breastmilk.

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Driving

Caution

Tofocom 200 mg/300 mg Tablet may cause dizziness. So, drive or operate machinery only if you are alert.

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Liver

Caution

Dose adjustment may be needed. Please consult your doctor before taking Tofocom 200 mg/300 mg Tablet if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed. Please consult your doctor before taking Tofocom 200 mg/300 mg Tablet if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

Tofocom 200 mg/300 mg Tablet is not recommended for children below 12years.

FAQs

Tofocom 200 mg/300 mg Tablet belongs to a group of antiretroviral medicines used to treat HIV infection. Tofocom 200 mg/300 mg Tablet helps decrease the chance of developing AIDS (acquired immunodeficiency syndrome) and other HIV-related illnesses.
Tofocom 200 mg/300 mg Tablet is a combination of two drugs: Emtricitabine and Tenofovir disoproxil fumarate. Tofocom 200 mg/300 mg Tablet works by interfering with the working of nucleotide and nucleoside reverse transcriptase enzymes necessary for the reproduction of the virus. Together, Tofocom 200 mg/300 mg Tablet helps in treating HIV infection.
Please do not stop taking Tofocom 200 mg/300 mg Tablet without consulting your doctor, as it may reduce the effectiveness of anti-HIV therapy. Continue taking Tofocom 200 mg/300 mg Tablet for as long as your doctor has prescribed it to treat your condition effectually. Do not be reluctant to speak with your doctor if you experience any difficulty taking Tofocom 200 mg/300 mg Tablet.
Tofocom 200 mg/300 mg Tablet might cause lactic acidosis (excess of lactic acid in the blood), a rare but severe side effect, especially in women who are obese and people with liver disease. Consult a doctor immediately if you experience stomach pain, vomiting, nausea, drowsiness, and deep rapid breathing while taking Tofocom 200 mg/300 mg Tablet.
Tofocom 200 mg/300 mg Tablet does not cure HIV infection. However, Tofocom 200 mg/300 mg Tablet helps to decrease the chance of developing AIDS (acquired immunodeficiency syndrome) and other HIV-related illnesses such as cancer or serious infections.
HIV negative patients can take Tofocom 200 mg/300 mg Tablet to lower the chance of getting HIV infection if prescribed by the doctor. Before starting the treatment, you should have a negative HIV test and whilst taking Tofocom 200 mg/300 mg Tablet regular HIV tests for at least every 3months is advised.
Tofocom 200 mg/300 mg Tablet may cause bone problems such as soft bones, thin bones, and bone pain. A regular bone density test is advised while taking Tofocom 200 mg/300 mg Tablet. For good bone health, take calcium and vitamin D supplements as told by the doctor.

Country of origin

India
Other Info - TO53539

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