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Written By ,
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Nov 30, 2024 | 3:18 PM IST
TOBAREN D DROPS 5ML is used to treat Bacterial eye infections and Bacterial ear infections. It contains Tobramycin (antibiotics) and Dexamethasone (corticosteroids). Tobramycin works by inhibiting the growth of bacteria. Dexamethasone blocks the chemical messenger in the brain, which is responsible for causing inflammation (redness, itching, and swelling). Thus, it treats and relieves bacterial infections.
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Prescription drug

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Manufacturer/Marketer

Warren Pharmaceuticals Pvt Ltd

Consume Type

EYE/EAR

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About TOBAREN D DROPS 5ML

TOBAREN D DROPS 5ML is a combination of one antibiotic and one corticosteroid used to treat bacterial eye and ear infections. It is used to treat eye infections such as conjunctivitis (infection of the outer white membrane of the eyeball), corneal ulcers (ulcer that occurs in the transplant membrane of the eye called the cornea), acute bacterial otitis media (an infection of the middle ear), and otitis externa (an infection in the ear canal). Eye infections are contagious and can pass from one to another. Signs and symptoms include pink or red-toned eyes, itching in areas of eyes, teary eyes, thick discharge around eyes/ears, ear discomfort, etc. 

TOBAREN D DROPS 5ML is a combination medicine that contains Tobramycin and Dexamethasone. Tobramycin is an aminoglycoside antibiotic which inhibits the growth of bacteria by interfering with protein synthesis and leads to cell death. Dexamethasone is a corticosteroid medicine that reduces swelling and redness by preventing infection-fighting white blood cells (WBCs). 

TOBAREN D DROPS 5ML is an external preparation and should be administered as advised by your doctor. TOBAREN D DROPS 5ML may cause certain common side effects, including (when used as eye drops) redness, itching, swelling, burning sensation, tearing, and temporary blurred vision (when used as ear drops), including ear pain and discomfort, discharge from ears, etc. Most of these side effects do not require medical attention and gradually subside over a time span. However, if the side effects persist for an extended period of time, consult your doctor. 

TOBAREN D DROPS 5ML should be avoided if you are allergic to it, other aminoglycoside antibiotics or any other ingredients present in it. Inform your doctor if you are on any topical nonsteroidal anti-inflammatory drugs (NSAIDs), as TOBAREN D DROPS 5ML combined with topical NSAIDs may cause your eye wound to heal more slowly. Avoid wearing contact lenses during the treatment of ocular infection or inflammation, as it can worsen the condition. Tell your doctor about all your current medications and medical history before using TOBAREN D DROPS 5ML. Inform your doctor if you have any vision or hearing problems after using this medication. Tell your doctor if you are pregnant or breastfeeding. TOBAREN D DROPS 5ML is not recommended for use in children below 2 years of age. 

Uses of TOBAREN D DROPS 5ML

Treatment of Bacterial eye infections and Bacterial ear infections

Medicinal Benefits

TOBAREN D DROPS 5ML is a combination medicine that contains Tobramycin (antibiotics) and Dexamethasone (corticosteroids). Tobramycin works by inhibiting the growth of bacteria. Dexamethasone blocks the chemical messenger in the brain responsible for causing inflammation (redness, itching, and swelling). As a result, it lowers inflammation, which could worsen the condition. TOBAREN D DROPS 5ML is used to prevent and treat inflammation and prevent possible bacterial infection of the eye after cataract surgery in adults and children above two years of age. 

Directions for Use

Eye drops: Wash your hands thoroughly with water before and after use. Tilt your head and pull down the lower eyelid to create a small sac. Squeeze the prescribed amount of dose into the sac using the dropper. Close your eyes for about 2 to 3 minutes. Wipe any excess liquid with a tissue. Do not wipe or rinse the dropper tip after use. Place the dropper back on the bottle and tighten the cap. Ear drops: Wash your hands thoroughly with water before and after use. Tilt your head towards the side, take the prescribed dose with the dropper, and squeeze the drops in the ear.

Storage

Store in a cool and dry place away from sunlight

Side Effects of TOBAREN D DROPS 5ML

  • Eye redness
  • Burning sensation
  • Ear discomfort
  • Discharge from the ear
  • Ear pain
  • Dry eyes
  • Ringing sound 

Drug Warnings

  • It is for external use only. If you are allergic to TOBAREN D DROPS 5ML or any other medicines, please tell your doctor. Consult your doctor before using TOBAREN D DROPS 5ML if you are pregnant or breastfeeding. 
  • TOBAREN D DROPS 5ML is not recommended for children below 2 years of age. 
  • You are advised to remove soft contact lenses before using TOBAREN D DROPS 5ML as it contains a preservative that may cause eye irritation and discolouration of soft contact lenses. You can reinsert contact lenses after 15 minutes of using TOBAREN D DROPS 5ML. 
  • Do not use the topical non-steroidal inflammatory drug while using TOBAREN D DROPS 5ML. TOBAREN D DROPS 5ML contains dexamethasone; if you use a topical non-steroidal inflammatory drug and dexamethasone together, it may delay the healing of your eye wound. 
  • If you have diabetes, please consult your doctor before using TOBAREN D DROPS 5ML. The risk of intraocular pressure (glaucoma) and cataract formation is increased in diabetic patients. 
  • TOBAREN D DROPS 5ML may cause temporary vision problems (blurred vision), so be cautious while driving and operating machinery. 

Drug Interactions

Drug-drug interactions: TOBAREN D DROPS 5ML may interact with other antibiotics (e.g., vancomycin, gentamicin, kanamycin, streptomycin, cephalothin), pain relievers (e.g., diclofenac, bromfenac) antiviral (e.g., ritonavir, cobicistat, boceprevir, amprenavir, atazanavir), antifungal (e.g., itraconazole, ketoconazole, miconazole, posaconazole, voriconazole), antidiabetics (e.g., metformin, canagliflozin, glimepiride, pioglitazone), smallpox vaccine.

Drug-food interactions: No food interactions found.

Drug-disease interactions: TOBAREN D DROPS 5ML should be used with caution in patients with a corneal transplant, diabetes, myasthenia gravis, and Parkinson's disease.

Drug-Drug Interactions Checker List

  • VANCOMYCIN
  • GENTAMICIN
  • STREPTOMYCIN
  • DICLOFENAC
  • RITONAVIR
  • ITRACONAZOLE
  • PIOGLITAZONE
  • VORICONAZOLE
  • METFORMIN
  • ATAZANAVIR
  • BOCEPREVIR

Habit Forming

No

Diet & Lifestyle Advise

  • Sleep for at least 6-8 hours to rejuvenate your eyes naturally.
  • Wash your eyes with clean water at least 2-3 times a day
  • Manage stress, eat healthily, drink plenty of water, exercise regularly, and get plenty of sleep.
  • Placing cooled tea bags on your eyes while they are closed can be a way to relax and unwind.
  • Avoid pricking your ears with cotton buds or fingers as it can scratch the skin and allows germs which result in infection.
  • The ear infection can also occur due to improper cleaning of ears after bathing or swimming. Hence, cleaning your ears thoroughly with a clean and dry cloth is advised.

Special Advise

  • Do not take TOBAREN D DROPS 5ML on your own, as self-medication may lead to antibiotic resistance in which antibiotics fail to act against specific bacterial infections.
  • Using TOBAREN D DROPS 5ML for prolonged may result in a new fungal eye infection (secondary infection). Do not use TOBAREN D DROPS 5ML for longer than prescribed.
  • TOBAREN D DROPS 5ML should not be administered directly into the eye's anterior chamber.

Disease/Condition Glossary

Bacterial eye infection: Bacterial eye infection occurs when pathogenic bacteria infiltrate any part of the eye, including the eyeball, conjunctiva, and cornea. Conjunctivitis, keratitis, and other bacterial eye infections are common. The inflammation or infection of the conjunctiva (white part of the eye) and the inner eyelid is known as conjunctivitis (pink eye). It is a highly contagious infection spread through eye secretions. Redness, itchiness, and discharge or crusting around the eye are all symptoms. Keratitis is an inflammation of the cornea caused by contact lens use, injury, diabetes, or surgery.

Bacterial ear infection: Bacterial ear infection occurs when pathogenic bacteria infiltrate any part of the ear, including the eardrum, middle ear, and ear canal. Acute otitis media and otitis externa are two common bacterial ear infections. Acute bacterial otitis media is a middle ear infection that occurs behind the eardrum. It is most prevalent in children. Otitis externa (Swimmer's ear) is an infection of the ear canal, which connects to the eardrum. It is primarily caused by frequent pricking of the ear with cotton buds or inserting fingers into the ear, which results in ear infections.

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Alcohol

Caution

The interaction of TOBAREN D DROPS 5ML with alcohol is unknown. Consult your doctor before consuming alcohol during the treatment with TOBAREN D DROPS 5ML.

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Pregnancy

Caution

If you are pregnant, consult your doctor before using TOBAREN D DROPS 5ML. It is given to pregnant women only if the doctor thinks the benefits outweigh the risks.

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Breast Feeding

Caution

Consult Your doctor before using TOBAREN D DROPS 5ML if you are breastfeeding. Your doctor will prescribe TOBAREN D DROPS 5ML only if the benefits outweigh the risks.

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Driving

Caution

TOBAREN D DROPS 5ML usually causes temporarily blurred vision and affects your driving ability when used in the eyes. Hence, avoid driving or operating machines until your vision is clear after using this medicine.

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Liver

Safe if prescribed

TOBAREN D DROPS 5ML can be used in patients with liver disease if prescribed by a doctor.

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Kidney

Safe if prescribed

TOBAREN D DROPS 5ML can be used in patients with kidney disease if prescribed by a doctor.

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Children

Caution

TOBAREN D DROPS 5ML should be used in children when prescribed by a child specialist. This medicine is not advised for use in children below two years of age.

Country of origin

India
Other Info - TOB0005

FAQs

TOBAREN D DROPS 5ML is used to treat Bacterial eye infections and Bacterial ear infections.
TOBAREN D DROPS 5ML contains tobramycin and dexamethasone. Tobramycin is an aminoglycoside antibiotic. It acts by inhibiting bacteria's growth. It binds to the proteins in the bacteria, disrupting the cell functions and eventually leading to bacterial death. Dexamethasone is a corticosteroid that blocks the production of certain chemical messengers (prostaglandins) that make the eye red, swollen, and itchy.
Do not take TOBAREN D DROPS 5ML on your own, as self-medication may lead to antibiotic resistance in which antibiotics fail to act against specific bacterial infections.
If you have diabetes, TOBAREN D DROPS 5ML can increase the risk of intraocular pressure (glaucoma) and cataract formation in diabetic patients. However, please consult your doctor before using TOBAREN D DROPS 5ML.
If you miss a dose of TOBAREN D DROPS 5ML, take the missed dose as soon as you remember it. However, if it's almost time for the next dose, do not take a double dose to make up for a missed one.
It is advised to use TOBAREN D DROPS 5ML only for the prescribed period as long-term usage of TOBAREN D DROPS 5ML may cause a new fungal eye infection (secondary infection). Prolonged use of corticosteroids may result in glaucoma, damage to the optic nerve, and defects in visual acuity and fields of vision. Intraocular pressure should be monitored if this product is used for ten days or longer.
TOBAREN D DROPS 5ML may cause common side effects, such as eye redness, itching, swelling, burning sensation, tearing, and dry eyes. Most of these side effects of TOBAREN D DROPS 5ML do not require medical attention and gradually resolve over time. However, if the side effects persist, please consult your doctor.
TOBAREN D DROPS 5ML does not cause blindness. However, it contains dexamethasone (a corticosteroid), when used for a long time may lead to vision loss or blindness in rare cases. If you notice any changes in your vision while using TOBAREN D DROPS 5ML, contact your doctor immediately for advice.
You are advised to remove contact lenses before using TOBAREN D DROPS 5ML, as it contains a preservative that may increase the risk of eye irritation and cause discolouration of the lenses. It is best to remove your lenses before applying TOBAREN D DROPS 5ML and wait at least 15 minutes before reinserting them. Always consult your doctor for personalized advice.
You can use TOBAREN D DROPS 5ML for a bacterial ear infection, but only if advised by your doctor. Always consult your doctor first to ensure it is the right treatment for your condition.
You can use multiple eye drops prescribed by your doctor, but it is important to space them out to prevent any interaction. It is recommended to wait at least 5 minutes between each drop to ensure the first one is absorbed properly. If you are unsure, please consult your doctor for specific guidance.

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