Tizafree 2 Tablet belongs to the class of drugs called skeletal muscle relaxants used to treat muscle spasticity (muscles become heavy, stiff, and difficult to move) and relieve discomfort due to acute, painful musculoskeletal conditions like stiffness, tension, rigidity, and muscle spasms. Muscle spasticity is a condition in which muscles become stiff, contract, or cause involuntary spasm, making it difficult to move, walk, or talk, which can sometimes be painful and uncomfortable.

Tizafree 2 Tablet contains Tizanidine that works on the centers of the spinal cord and brain. This helps relieve muscle stiffness and improves muscle movements, thereby relieves pain due to muscle spasms.

Take Tizafree 2 Tablet with or without food as advised by your doctor and swallow whole with a glass of water. Do not crush, chew or break it. Your doctor will advise you how often you take your tablets based on your medical condition. In some cases, you may experience drowsiness, dizziness, dry mouth, flu-like symptoms, vomiting, constipation, nervousness, sore throat, runny nose, blurred vision, or weakness. Most of these side effects of Tizafree 2 Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Tizafree 2 Tablet or any other medicines, please tell your doctor. Tizafree 2 Tablet is not recommended for children as the safety and effectiveness were not established. Please consult a doctor if you are pregnant or breastfeeding before taking Tizafree 2 Tablet . Do not consume alcohol with Tizafree 2 Tablet as it may increase the risk of adverse effects. Avoid taking Tizafree 2 Tablet with fluvoxamine and ciprofloxacin as it may cause adverse effects such as slurred speech, dizziness, weakness, confusion, low blood pressure, or drowsiness. You are advised not to take more than 3 doses of Tizafree 2 Tablet in a single day as too much of Tizafree 2 Tablet may cause liver damage. If you have low blood pressure, liver or kidney diseases, inform your doctor before taking Tizafree 2 Tablet .

Tizafree 2 Tablet contains Tizanidine used to treat muscle spasms. It works on the centers of the spinal cord and brain. This helps relieve muscle stiffness and improves muscle movements, thereby relieves pain due to muscle spasms.

• Drowsiness
• Dizziness
• Dry mouth
• Flu-like symptoms
• Vomiting
• Constipation
• Nervousness
• Sore throat
• Runny nose
• Blurred vision
• Weakness
• Tingling sensation in the arms, legs, hands, and feet

If you are allergic to Tizafree 2 Tablet or any other medicines, please tell your doctor. Take Tizafree 2 Tablet either with food or without food but in the same way, each time as switching between them may reduce the effectiveness of Tizafree 2 Tablet or increase adverse effects. Tizafree 2 Tablet is not recommended for children as safety and effectiveness were not established. Please consult a doctor if you are pregnant or breastfeeding before taking Tizafree 2 Tablet . Do not consume alcohol with Tizafree 2 Tablet as it may increase the risk of adverse effects. Avoid taking Tizafree 2 Tablet with fluvoxamine and ciprofloxacin as it may cause adverse effects such as slurred speech, dizziness, weakness, confusion, low blood pressure, or drowsiness. You are advised not to take more than 3 doses of Tizafree 2 Tablet in a single day as too much of Tizafree 2 Tablet may cause liver damage. If you have low blood pressure, liver or kidney diseases, inform your doctor before taking Tizafree 2 Tablet .

Drug-Drug Interactions: Tizafree 2 Tablet may have interaction with antidepressants (escitalopram, duloxetine, sertraline, fluvoxamine), anticonvulsants (pregabalin, topiramate), anti-allergic drugs (diphenhydramine, cetirizine), pain relievers (acetaminophen + hydrocodone), an anti-anxiety drug (alprazolam), sedative-hypnotic drug (zolpidem), bronchodilator (albuterol), antibiotic (ciprofloxacin).

Drug-Food Interactions: Tizafree 2 Tablet may interact with caffeine. Therefore, avoid intake of caffeine with Tizafree 2 Tablet as it may cause low blood pressure and dizziness. Also, avoid intake of alcohol with Tizafree 2 Tablet as it may increase the risk of adverse effects.

Drug-Disease Interactions: If you have low blood pressure, liver or kidney diseases, inform your doctor before taking Tizafree 2 Tablet .

• ESCITALOPRAM
• DULOXETINE
• SERTRALINE
• FLUVOXAMINE
• PREGABALIN
• TOPIRAMATE
• DIPHENHYDRAMINE
• CETIRIZINE
• ALPRAZOLAM
• ZOLPIDEM
• ALBUTEROL
• CIPROFLOXACIN
• ACETAMINOPHEN+HYDROCODONE

• Regular exercise helps in muscle stretching so that they are less likely to spasm, tear and sprain. Mild exercises such as jogging and walking are helpful for muscle stretching.

• Massages can also be helpful.

• Avoid freezing and hot temperatures.

• Avoid wearing tight-fitting clothes, instead, wear loose garments.

• Rest well, get plenty of sleep.

• To avoid developing pressure sores, change your position at least every two hours.

• Hot or cold therapy can help treat muscle spasms. Apply an ice-pack or hot-pack on the muscle for 15-20minutes.

• Stay hydrated, drink plenty of water.

Regular blood tests are recommended to monitor liver functioning while taking Tizafree 2 Tablet .

Muscle spasticity is a condition in which muscles become stiff, contract, or cause involuntary spasm making it difficult to move, walk or talk, which can be painful and uncomfortable sometimes. When the nerve impulses that control the muscle movements are damaged or interrupted, it could lead to muscle spasticity. Symptoms include muscle tightness, joint stiffness, unusual posture, difficulty in moving, pain in affected muscles and joints. Fatigue (weakness), stress, extreme heat or cold, infection, and tight clothing can trigger muscle spasms. Muscle relaxants and exercise can treat muscle spasticity. Muscle relaxants sedate the muscle and help in inhibiting painful contractions. Whereas, exercise helps in muscle stretching to be less likely to spasm, tear and sprain.