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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy

Tikleen-90 Tablet is taken to prevent heart attack or stroke in people at high risk of heart disease. It helps to prevent blood clots in people with acute coronary syndrome (heart doesn't receive enough oxygen) who have had stents placed in blood vessels in their heart. It contains Ticagrelor, which prevents blood clot formation in the blood vessels by making platelets less sticky. In some cases, you may experience dyspnea (shortness of breath), tightness in the chest, blurred vision, nosebleeds, dizziness, faintness, or lightheadedness. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Composition :

TICAGRELOR-90MG

Manufacturer/Marketer :

Ipca Laboratories Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Tikleen-90 Tablet

Tikleen-90 Tablet belongs to the antiplatelet drugs (blood thinners) primarily taken to prevent heart attack or stroke in people at high risk of heart disease. Tikleen-90 Tablet  helps to prevent blood clots in people with acute coronary syndrome (heart doesn't receive enough oxygen) who have had stents placed in blood vessels in their heart. A heart attack occurs when a blood clot blocks the blood flow to the heart. This blockage of arteries is often an accumulation of cholesterol, fat, and other substances, which form plaque in the arteries that feed the heart (coronary arteries). A heart attack signs include chest pain, upper body pain, sweating, nausea, fatigue, and trouble breathing.

Tikleen-90 Tablet contains Ticagrelor, which is a blood thinner that prevents clot formation in the blood vessels. Platelets are blood cells that stick together and block any cuts and breaks in blood vessels. But platelets can stick together inside already narrowed blood vessels to form a clot in people at risk of heart attack or stroke. The clot can stop blood from flowing to the heart or brain and cause a heart attack or stroke. Here, Tikleen-90 Tablet slows the blood's clotting action by making platelets less sticky.

Your doctor will advise you how often you take Tikleen-90 Tablet based on your medical condition. In some cases, you may experience dyspnea (shortness of breath), tightness in the chest, blurred vision, nosebleeds, dizziness, faintness, or lightheadedness. If side effects are persistent, talk to your doctor. Tikleen-90 Tablet may cause you to bleed more easily. You should not take Tikleen-90 Tablet if you have bleeding in your brain, a problem with blood flow, or any other bleeding risk factor.

Before taking the Tikleen-90 Tablet , let your doctor know about all your allergic or hypersensitivity reactions to medicines or food. Tikleen-90 Tablet should not be stopped even if you feel better without consulting your doctor, as stopping a sudden intake of Tikleen-90 Tablet may worsen your condition and increase the risk of a future heart attack. The patient should inform the doctor that they are taking Tikleen-90 Tablet before any surgery is scheduled or any new medicine is taken. Don't take Tikleen-90 Tablet before or after having heart bypass surgery. Before using Tikleen-90 Tablet , consult your doctor if you are pregnant, planning to become pregnant, or breastfeeding.

Uses of Tikleen-90 Tablet

Prevention of Heart attack, Stroke, Acute Coronary Syndrome.

Directions for Use

Tablet: Swallow it as a whole with water; do not crush, break or chew it.Orodispersible tablet/mouth-dissolving tablet: Keep the tablet in the mouth and allow it to disintegrate. Do not swallow as a whole. Avoid handling the strip with wet hands.

Medicinal Benefits

Tikleen-90 Tablet is an antiplatelet (blood thinner) and plays a vital role in preventing the formation of harmful blood clots in your blood vessels. Tikleen-90 Tablet work by preventing platelets from sticking together, thereby decreasing the formation of harmful blood clots. Thus, it reduces the risk of heart attack, stroke, and acute coronary syndrome (heart doesn't receive enough oxygen or blood) in heart disease patients and patients who have undergone recent heart surgery with a stent.

How Tikleen-90 Tablet Works

Tikleen-90 Tablet contains Ticagrelor, which is a blood thinner that prevents clot formation in the blood vessels. Platelets are blood cells that stick together and block any cuts and breaks in blood vessels. But platelets can stick together inside already narrowed blood vessels to form a clot in people at risk of heart attack or stroke. The clot can stop blood from flowing to the heart or brain and cause a heart attack or stroke. Here, Tikleen-90 Tablet slows the blood's clotting action by making platelets less sticky.

Storage

Store in a cool and dry place away from sunlight
Side effects of Tikleen-90 Tablet
Here are the seven steps to manage medication-triggered Dyspnea (Difficulty Breathing or Shortness of Breath):
  • Tell your doctor immediately if you experience shortness of breath after taking medication.
  • Your doctor may adjust the medication regimen or dosage or give alternative medical procedures to minimize the symptoms of shortness of breath.
  • Monitor your oxygen levels and breathing rate regularly to track changes and potential side effects.
  • For controlling stress and anxiety, try relaxation techniques like deep breathing exercises, meditation, or yoga.
  • Make lifestyle changes, such as quitting smoking, exercising regularly, and maintaining a healthy weight.
  • Seek emergency medical attention if you experience severe shortness of breath, chest pain, or difficulty speaking.
  • Follow up regularly with your doctor to monitor progress, adjust treatment plans, and address any concerns or questions.
Managing Medication-Triggered Epistaxis (Nosebleed): A Step-by-Step Guide:
  • If you experience nosebleeds or unusual bleeding after taking medication, seek medical attention right away and schedule an appointment to discuss your symptoms with your doctor.
  • Your doctor may adjust your treatment plan by changing the dosage, switching to a different medication, or stopping the medication.
  • If your doctor advises, take steps to manage bleeding and promote healing, such as applying pressure, using saline nasal sprays, or applying a cold compress, using humidifiers, avoiding blowing or picking your nose, and applying petroleum jelly to the nostrils.
  • Schedule follow-up appointments with your doctor to monitor progress, adjust treatment plans, and prevent future episodes.
  • Increased creatinine levels must be corrected immediately with the help of a doctor.
  • Reduce strenuous activities that can lead to muscle breakdown and production of creatinine.
  • Sleep for 7-8 hours per night to assist your body in repairing and rebuilding tissue.
  • Manage your blood pressure by implementing changes in lifestyle like losing weight, reducing stress and exercising regularly.
  • Avoid smoking and drinking alcohol.
Managing back pain as a side effect of medication requires a combination of self-care techniques, lifestyle modifications, and medical interventions. Here are the steps:
  • Talk to your doctor about your back pain and potential medication substitutes or dose changes.
  • Try yoga or Pilates and other mild stretching exercises to increase flexibility and strengthen your back muscles.
  • To lessen the tension on your back, sit and stand upright and maintain proper posture.
  • To alleviate discomfort and minimize inflammation, apply heat or cold packs to the afflicted area.
  • Under your doctor's supervision, think about taking over-the-counter painkillers like acetaminophen or ibuprofen.
  • Make ergonomic adjustments to your workspace and daily activities to reduce strain on your back.
  • To handle tension that could make back pain worse, try stress-reduction methods like deep breathing or meditation.
  • Use pillows and a supportive mattress to keep your spine in the right posture as you sleep.
  • Back discomfort can worsen by bending, twisting, and heavy lifting.
  • Speak with a physical therapist to create a customized training regimen to increase back strength and flexibility.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.

What if I have taken an overdose of Tikleen-90 Tablet

Do not take more than the prescribed dose of Tikleen-90 Tablet as it may cause overdose resulting in excessive bleeding. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

You should avoid taking Tikleen-90 Tablet if you are allergic to Tikleen-90 Tablet or any active and inactive ingredients present in it.  Let your doctor know if you have a medical condition that causes bleeding such as hemophilia, stomach ulcer, or bleeding in your head or bowel. Caution is required before giving Tikleen-90 Tablet to the kidney or liver problems patients. People affected with respiratory problems like asthma, nasal polyps, or rhinitis should consult a doctor before intake of Tikleen-90 Tablet . Tikleen-90 Tablet is not recommended for the breastfeeding mother as it passes into the breast milk. The safety and effectiveness in children less than 18 years of age have not been established, so Tikleen-90 Tablet should not be given to them.

Drug-Drug Interactions

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TicagrelorKetoconazole
Critical
TicagrelorIndinavir
Critical

Drug-Drug Interactions

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TicagrelorKetoconazole
Critical
How does the drug interact with Tikleen-90 Tablet:
Co-administration of Tikleen-90 Tablet with ketoconazole can cause severe bleeding.

How to manage the interaction:
Taking Tikleen-90 Tablet with Ketoconazole is not recommended as it can cause an interaction, it can be taken if prescribed by the doctor. However, if you experience any unusual bleeding or bruising, swelling, vomiting, blood in your urine or stools, headache, dizziness, or weakness, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
TicagrelorIndinavir
Critical
How does the drug interact with Tikleen-90 Tablet:
Using Tikleen-90 Tablet together with indinavir can cause risk of bleeding.

How to manage the interaction:
Taking Tikleen-90 Tablet with Indinavir is not recommended, but it can be taken together if prescribed by a doctor. However, consult a doctor if you experience any unusual bleeding or bruising, swelling, vomiting, blood in your urine or stools, headache, dizziness, or weakness. Do not discontinue any medications without consulting a doctor.
TicagrelorConivaptan
Critical
How does the drug interact with Tikleen-90 Tablet:
Co-administration of Tikleen-90 Tablet with Conivaptan can increase the risk of bleeding.

How to manage the interaction:
Taking Tikleen-90 Tablet with Conivaptan is not recommended, please consult your doctor before taking it. However, if you experience unusual bleeding or bruising, swelling, vomiting, blood in your urine or stools, headache, dizziness, or weakness contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
TicagrelorMifepristone
Critical
How does the drug interact with Tikleen-90 Tablet:
Co-administration of Mifepristone with Tikleen-90 Tablet can increase the risk of vaginal bleeding in women.

How to manage the interaction:
Taking Tikleen-90 Tablet with Mifepristone is not recommended, but can be taken together if prescribed by a doctor. However, consult your doctor if you experience any symptoms like heavy period bleed for more than 7 days, weakness, tiredness, shortness of breath or paleness. Do not discontinue any medications without consulting a doctor.
TicagrelorVoriconazole
Critical
How does the drug interact with Tikleen-90 Tablet:
Using Tikleen-90 Tablet together with Voriconazole can significantly increase the blood levels of Tikleen-90 Tablet.

How to manage the interaction:
Taking Tikleen-90 Tablet with Voriconazole is not recommended, but it can be taken together if prescribed by a doctor. However, consult a doctor if you experience vomiting, headache, dizziness, or weakness. Do not discontinue any medications without consulting a doctor.
TicagrelorRitonavir
Critical
How does the drug interact with Tikleen-90 Tablet:
Taking Tikleen-90 Tablet with Ritonavir may significantly increase the blood levels of Tikleen-90 Tablet.

How to manage the interaction:
Taking Tikleen-90 Tablet with Ritonavir is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience any unusual bleeding or bruising, swelling, vomiting, blood in your urine or stools, headache, dizziness, or weakness. Do not discontinue any medications without consulting a doctor.
TicagrelorTelithromycin
Critical
How does the drug interact with Tikleen-90 Tablet:
Using Tikleen-90 Tablet together with telithromycin cause increase the blood levels of Tikleen-90 Tablet.

How to manage the interaction:
Taking Tikleen-90 Tablet with Telithromycin is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience any unusual bleeding or bruising, swelling, vomiting, blood in your urine or stools, headache, dizziness, or weakness. Do not discontinue any medications without consulting a doctor.
TicagrelorPosaconazole
Critical
How does the drug interact with Tikleen-90 Tablet:
Co-administration of posaconazole with Tikleen-90 Tablet can increase the risk of bleeding.

How to manage the interaction:
Taking Tikleen-90 Tablet with Posaconazole is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience any unusual bleeding or bruising, swelling, vomiting, blood in your urine or stools, headache, dizziness, or weakness. Do not discontinue any medications without consulting a doctor.
TicagrelorItraconazole
Critical
How does the drug interact with Tikleen-90 Tablet:
The blood levels and effects of Tikleen-90 Tablet may be greatly increased when combined with itraconazole.

How to manage the interaction:
Itraconazole and Tikleen-90 Tablet may interact, however if prescribed by a physician, they can be used together. While receiving therapy, you should consult a doctor if you develop any unusual bleeding or bruising, swelling, vomiting, blood in your urine or stools, headache, dizziness, or weakness. Without consulting a doctor, never stop taking any medication.
TicagrelorRifampicin
Severe
How does the drug interact with Tikleen-90 Tablet:
Taking Tikleen-90 Tablet with Rifampicin may significantly reduce the blood levels of Tikleen-90 Tablet, which may make the medication less effective.

How to manage the interaction:
Taking Rifampicin with Tikleen-90 Tablet together can result in an interaction, but it can be taken if your doctor has advised it. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Reducing weight and having a healthy BMI is very important in enhancing cardiac health.

  • 30 minutes of daily physical exercise can go a long way in preventing heart disease.

  • Avoid smoking to improve cardiac health.

  • Invest in a healthy, balanced diet. Avoid fatty foods, keep your cholesterol in check and load up on the green leafy vegetables, fish, lean meats, nuts and dry fruits. 

  • Reducing stress is very important in keeping a healthy heart. Try yoga and meditation for a relaxed state of mind.

Habit Forming

No

Therapeutic Class

PLATELET AGGREGATION INHIBITOR

Tikleen-90 Tablet Substitute

Substitutes safety advice
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  • Brilinta 90 mg Tablet 14's

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    37.96per tablet
  • Brilinta 90 mg Tablet 180's

    by AYUR

    24.95per tablet
  • Torplat 90 Tablet 14's

    by AYUR

    25.30per tablet
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Alcohol

Unsafe

It is unsafe to consume alcohol since it may worsen the side effects like dizziness and increases blood pressure.

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Pregnancy

Caution

Please consult the doctor. There are no adequate and well-controlled studies on pregnant women. Your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Unsafe

Tikleen-90 Tablet may pass into breast milk and may cause side effects in a breastfed child. Please consult your doctor before starting Tikleen-90 Tablet .

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Driving

Caution

Do not drive or operate machinery if you experience dizziness or drowsiness while using Tikleen-90 Tablet .

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Liver

Caution

Let your doctor know if you had or have any history of liver disease or hepatic impairment. Your doctor will weigh the benefits and potential risks before prescribing Tikleen-90 Tablet . However, Tikleen-90 Tablet is not recommended in patients with severe liver problems.

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Kidney

Caution

Let your doctor know if you had or have any history of kidney diseases/conditions. Your doctor will weigh the benefits and potential risks before prescribing Tikleen-90 Tablet . However, Tikleen-90 Tablet is not recommended in patients with severe kidney problems.

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Children

Caution

Tikleen-90 Tablet is not recommended for children below the age of 18 years. The safety and effectiveness of Tikleen-90 Tablet have not been established in children.

FAQs

Tikleen-90 Tablet is primarily used to prevent heart attack or stroke in people at high risk of heart disease. It helps to prevent blood clots in people with acute coronary syndrome (the heart doesn't receive enough oxygen) who have had stents placed in blood vessels in their heart.

If the Tikleen-90 Tablet is taken every day, the Tikleen-90 Tablet stops platelets from clumping together to form unwanted blood clots and prevents heart attacks and strokes.

Yes, taking Tikleen-90 Tablet can increase the risk of bleeding. So, please be very cautious while cutting fingernails or toenails, shaving, or using sharp objects to avoid bleeding.

Please consult your doctor if Tikleen-90 Tablet needs to be stopped before undergoing surgery. The doctor might ask you to stop taking Tikleen-90 Tablet a few days before surgery since it can cause an increased risk of bleeding during surgery.

There might be a problem if you take herbal therapies with Tikleen-90 Tablet , especially those that affect blood like Ginkgo Biloba, Grapefruits, St John's wort plant extract used as an antidepressant. Taking together can increase your risk of bleeding. Tell your doctor if you are using any herbal supplements before taking Tikleen-90 Tablet .

No, Tikleen-90 Tablet may make it harder to breathe. Consult your doctor if the problem persists, he/she may adjust the dose or prescribe an alternative medicine.

Do not drink grapefruit juice while taking Tikleen-90 Tablet . Grapefruit juice may increase the blood-thinning effect of the medicine.

Tikleen-90 Tablet contains ticagrelor, which when taken with clopidogrel may increase the risk of bleeding. Consult the doctor before taking other medicines with Tikleen-90 Tablet .

Tikleen-90 Tablet should not be discontinued without a doctor's consultation. Stopping Tikleen-90 Tablet might increase the risk of a heart attack or stroke.

Tikleen-90 Tablet may cause blood in urine. Consult the doctor if you experience this.

Tikleen-90 Tablet might lower the blood pressure. Let the doctor know if you are taking anti-hypertensives (blood pressure-lowering medicines). Regular monitoring of blood pressure levels is advised.

Tikleen-90 Tablet can be taken with other medicines if prescribed by the doctor. Before starting Tikleen-90 Tablet inform the doctor if you are taking any other medicines to prevent interactions.

Tikleen-90 Tablet is an antiplatelet medicine which inhibits the aggregation of platelets that may cause a heart attack or stroke.

Limit alcohol consumption with Tikleen-90 Tablet as it might increase the risk of bleeding.

Tikleen-90 Tablet may cause significant, sometimes fatal bleeding. Inform the doctor if you have/had a condition that causes you to bleed more easily than normal; bleeding in your stomach, intestines, or brain; stomach ulcer; polyps (abnormal growths in the lining of the large intestine); a stroke or mini-stroke; or liver disease. Seek immediate medical attention if you experience unexplained, severe, long-lasting, or uncontrollable bleeding; red or black, tarry stools; pink or brown urine; vomit that is bloody or that looks like coffee grounds; or coughing up blood or blood clots.

Tikleen-90 Tablet works within 30 minutes of taking the first dose.

Country of origin

India

Manufacturer/Marketer address

142 AB, Kandivli Industrial Estate, Kandivli (West), Mumbai - 400 067, Maharashtra
Other Info - TIK0016

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