Thiobit Plus 325mg/4mg Tablet is a combination medication used to reduce and relieve orthopaedic, traumatic,  and rheumatologic disorders. It helps relieve muscle spasms (painful muscular contractions) associated with degenerative vertebral disorders, vertebral static problems, dorsal pain, low back pain, and torticollis (neck muscle contractions). 

Thiobit Plus 325mg/4mg Tablet is a combination of two drugs: Paracetamol (mild analgesic and antipyretic) and Thiocolchicoside (muscle relaxant). Paracetamol is an analgesic (relieves pain) and antipyretic (reduces fever) that works by inhibiting certain chemical messengers in the brain known as prostaglandins responsible for pain, inflammation and fever. Thiocolchicoside is a muscle relaxant that works on the centres of the spinal cord and brain. This helps relieve muscle stiffness and improves muscle movements, thereby relieves pain due to muscle spasms.

Take Thiobit Plus 325mg/4mg Tablet as prescribed. Your doctor will advise you on how often you take your tablets based on your medical condition. In some cases, you may experience diarrhoea, drowsiness or stomach pain. Most of these side effects of Thiobit Plus 325mg/4mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Thiobit Plus 325mg/4mg Tablet or any other medicines, please tell your doctor. Thiobit Plus 325mg/4mg Tablet is not recommended for children below 16 years of age. Avoid taking Thiobit Plus 325mg/4mg Tablet if you are pregnant as it may cause harm to the foetus. Thiobit Plus 325mg/4mg Tablet is excreted in breast milk. Therefore, Thiobit Plus 325mg/4mg Tablet is contraindicated in breastfeeding women as it may cause adverse effects on the baby. Inform your doctor if you experience abdominal pain or discomfort, dark urine, itching, fever, weakness, or yellowing of skin and eyes while taking Thiobit Plus 325mg/4mg Tablet as it indicates liver problems. Do not consume alcohol with Thiobit Plus 325mg/4mg Tablet as it may increase the risk of liver damage. If you have galactose intolerance, Lapp lactase deficiency, glucose-galactose malabsorption, G-6-PD deficiency (a hereditary condition resulting in low red blood cell counts), fits (epilepsy), muscular hypotonia (decreased muscle tone), flaccid paresis (loose and floppy limbs), kidney or liver diseases, inform your doctor before taking Thiobit Plus 325mg/4mg Tablet.

Thiobit Plus 325mg/4mg Tablet is a combination of two drugs, namely: Paracetamol and Thiocolchicoside used to treat pain due to muscle spasms. Paracetamol is an analgesic (relieves pain) and antipyretic (reduces fever) that works by inhibiting the production of certain chemical messengers in the brain known as prostaglandins responsible for pain and fever. Thiocolchicoside is a muscle relaxant that works on the centers of the spinal cord and brain. This helps relieve muscle stiffness and improves muscle movements, thereby relieves pain due to muscle spasms.

• Diarrhoea
• Drowsiness
• Stomach pain
• Fainting and drowsiness
• Nausea and Vomiting
• Dry mouth
• Headache
• Anemia

If you are allergic to Thiobit Plus 325mg/4mg Tablet or any other medicines, please tell your doctor. Thiobit Plus 325mg/4mg Tablet is not recommended for children below 16 years of age. Avoid taking Thiobit Plus 325mg/4mg Tablet if you are pregnant as it may cause harm to the fetus. Thiobit Plus 325mg/4mg Tablet is excreted in breast milk, so Thiobit Plus 325mg/4mg Tablet is contraindicated in breastfeeding women as it may cause adverse effects in the baby. Inform your doctor if you experience abdominal pain or discomfort, dark urine, itching, fever, weakness, yellowing of skin and eyes while taking Thiobit Plus 325mg/4mg Tablet as it indicates liver problems. Do not consume alcohol with Thiobit Plus 325mg/4mg Tablet as it may increase the risk of liver damage and gastrointestinal bleeding. If you have galactose intolerance, Lapp lactase deficiency, glucose-galactose malabsorption, G-6-PD deficiency (a hereditary condition resulting in low red blood cell counts), epilepsy (fits), muscular hypotonia (decreased muscle tone), flaccid paresis (loose and floppy limbs), kidney or liver diseases, inform your doctor before taking Thiobit Plus 325mg/4mg Tablet.

Drug-Drug Interaction: Thiobit Plus 325mg/4mg Tablet may have interaction with blood thinners (warfarin), anti-sickness drugs (domperidone, metoclopramide), lipid-lowering drugs (cholestyramine), antibiotics (chloramphenicol), antacid (ranitidine).

Drug- Food Interaction: Avoid foods rich in carbohydrates, pectin including jellies, cabbage, Brussels sprouts and broccoli as Thiobit Plus 325mg/4mg Tablet may interact with these foods. Also, avoid intake of alcohol with Thiobit Plus 325mg/4mg Tablet as it may increase the risk of liver damage.

Drug-Disease Interaction: If you have galactose intolerance, Lapp lactase deficiency, glucose-galactose malabsorption, G-6-PD deficiency (a hereditary condition resulting in low red blood cell counts), fits, muscular hypotonia (decreased muscle tone), flaccid paresis (loose and floppy limbs), kidney or liver diseases, inform your doctor before taking Thiobit Plus 325mg/4mg Tablet.

• WARFARIN
• DOMPERIDONE
• METOCLOPRAMIDE
• CHOLESTYRAMINE
• CHLORAMPHENICOL
• RANITIDINE

• Regular exercise helps in muscle stretching so that they are less likely to spasm, tear and sprain. Mild exercises such as jogging and walking are helpful for muscle stretching.
• Avoid wearing tight-fitting clothes, instead, wear loose garments.
• Rest well, and get plenty of sleep for at least 8 hours. 
• To avoid developing pressure sores, change your position at least every two hours.
• Hot or cold therapy can help treat muscle spasms. Apply an ice pack or hot-pack to the muscle for 15-20 minutes. 

Thiobit Plus 325mg/4mg Tablet may give false-positive results for urine glucose tests. Therefore, inform your doctor or lab technician that you are taking Thiobit Plus 325mg/4mg Tablet before undergoing any laboratory tests.

Pain is a symptom triggered by the nervous system, causing uncomfortable sensations in the body. Muscle spasm is the sudden involuntary contractions of the muscle, which can be painful and uncomfortable. When the nerve impulses that control the muscle movements are damaged or interrupted, it could lead to muscle spasms. Symptoms include muscle tightness, joint stiffness, unusual posture, difficulty in moving, pain in affected muscles and joints. Fatigue (weakness), stress, extreme heat or cold, infection, and tight clothing can trigger muscle spasms. Muscle relaxants and exercise can treat muscle spasms. Muscle relaxants sedate the muscle and help in inhibiting painful contractions. Whereas, exercise helps in muscle stretching to be less likely to spasm, tear and sprain.