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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 9, 2024 | 12:36 PM IST
Themiset Injection 5 ml is used to prevent nausea and vomiting during chemotherapy. It contains Palonosetron, which blocks the action of serotonin, a chemical that stimulates the vomiting centre (chemoreceptor trigger zone) located in the brain. Thus, it prevents nausea and vomiting. Common side effects of Themiset Injection 5 ml are diarrhoea, constipation, dizziness or headache.
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Prescription drug

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Manufacturer/Marketer

Themis Medicare Ltd

Consume Type

PARENTERAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Themiset Injection 5 ml

Themiset Injection 5 ml belongs to a class of drugs called antiemetics used to prevent nausea and vomiting during chemotherapy. Nausea is a feeling of uneasiness of the stomach that often comes before vomiting. On the other hand, vomiting is the forcible voluntary or involuntary emptying of stomach contents through the mouth.

Themiset Injection 5 ml contains Palonosetron which works by blocking the action of serotonin, a chemical that stimulates the vomiting centre (chemoreceptor trigger zone – CTZ) located in the brain. Thus, it prevents nausea and vomiting.

Themiset Injection 5 ml will be administered by a healthcare professional; do not self-administer. In some cases, you may experience diarrhoea, constipation, dizziness or headache. Most of these side effects of Themiset Injection 5 ml do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Themiset Injection 5 ml or any other medicines, please tell your doctor. Themiset Injection 5 ml may be given to children above 1 month in doses as advised by a doctor based on the child's body weight. If you are pregnant or breastfeeding, please inform your doctor before taking Themiset Injection 5 ml. Drive only if you are alert as Themiset Injection 5 ml may cause tiredness or dizziness. You are recommended to avoid heavy meals and take small nourishing snacks throughout the day. Drink plenty of water to avoid dehydration.

Uses of Themiset Injection 5 ml

Treatment of Nausea and vomiting

Medicinal Benefits

Themiset Injection 5 ml contains Palonosetron which blocks the action of serotonin, a chemical that stimulates the vomiting centre (chemoreceptor trigger zone – CTZ) located in the brain. Thus, it prevents nausea and vomiting during chemotherapy.

Directions for Use

Themiset Injection 5 ml will be administered by a healthcare professional; do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Themiset Injection 5 ml

  • Diarrhoea
  • Constipation
  • Dizziness
  • Headache

Drug Warnings

If you are allergic to Themiset Injection 5 ml or any other medicines, please tell your doctor. Themiset Injection 5 ml may be given to children above 1 month in doses as advised by a doctor based on the child's body weight. If you are pregnant or breastfeeding, please inform your doctor before taking Themiset Injection 5 ml. Drive only if you are alert as Themiset Injection 5 ml may cause tiredness or dizziness. You are recommended to avoid heavy meals and take small nourishing snacks throughout the day. Drink plenty of water to avoid dehydration.

Drug Interactions

Drug-Drug Interaction: Themiset Injection 5 ml may interact with antidepressants (citalopram, fluoxetine, fluvoxamine, paroxetine, sertraline, escitalopram, duloxetine, venlafaxine), heart-related drugs or high blood pressure (quinidine, amiodarone, nicardipine), antibiotics (moxifloxacin, erythromycin), antiemetic (domperidone), antipsychotic drugs (thioridazine, quetiapine, chlorpromazine, haloperidol).

Drug-Food Interaction: No interactions found.

Drug-Disease Interaction: If you have blocked bowel, repeated constipation, heart problems or imbalance of potassium and magnesium in the blood, inform your doctor before taking Themiset Injection 5 ml.

Drug-Drug Interactions Checker List

  • CITALOPRAM
  • FLUVOXAMINE
  • PAROXETINE
  • SERTRALINE
  • ESCITALOPRAM
  • DULOXETINE
  • VENLAFAXINE
  • QUINIDINE
  • AMIODARONE
  • NICARDIPINE
  • MOXIFLOXACIN
  • ERYTHROMYCIN
  • DOMPERIDONE
  • THIORIDAZINE
  • QUETIAPINE
  • CHLORPROMAZINE
  • HALOPERIDOL

Habit Forming

No

Diet & Lifestyle Advise

  • Eat a healthy diet and a low-fat diet, especially in small portions, as it will be easy for digestion. Avoid eating over-sweet food and include more salty food, especially if you have been vomiting.
  • Also, if you like to vomit at a specific time, avoid eating your favourite food at that particular time as your taste for that food may get turned off.
  • Drink any other liquid at least 30 minutes after eating food.
  • If the smell of food makes you feel sick (vomit), do not cook food as it may worsen your condition. Let someone else do the cooking or use prepared food from the freezer.

Disease/Condition Glossary

Nausea and vomiting: Nausea is a feeling of uneasiness of the stomach that often comes before vomiting. On the other hand, vomiting is the forcible voluntary or involuntary emptying of stomach contents through the mouth. In short, nausea and vomiting are not diseases but are symptoms of many conditions like infections, motion sickness, an early stage of pregnancy, and gastroparesis (slow stomach emptying). There is a receptor located in our brain known as the chemoreceptor zone (CTZ) that controls vomiting.

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Alcohol

Caution

The interaction of alcohol with Themiset Injection 5 ml is unknown. Please consult a doctor before consuming alcohol with Themiset Injection 5 ml.

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Pregnancy

Consult your doctor

Themiset Injection 5 ml is given to pregnant women only if the doctor thinks the benefits outweigh the risks. Please inform your doctor if you are pregnant.

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Breast Feeding

Consult your doctor

Please inform your doctor before taking Themiset Injection 5 ml if you are breastfeeding. Themiset Injection 5 ml is given to breastfeeding women only if the doctor thinks the benefits are greater than the risks.

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Driving

Caution

Themiset Injection 5 ml may cause tiredness or dizziness in some people. Therefore, avoid driving or operating heavy machinery if you feel tired or dizzy after taking Themiset Injection 5 ml.

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Liver

Safe if prescribed

Themiset Injection 5 ml may be safe to use in patients with liver problems if prescribed by a doctor. However, if you have any concerns regarding this, please discuss them with your doctor.

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Kidney

Safe if prescribed

Themiset Injection 5 ml may be safe to use in patients with kidney problems if prescribed by a doctor. However, if you have any concerns regarding this, please discuss them with your doctor.

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Children

Caution

Themiset Injection 5 ml may be given to children above 1 month in doses as advised by a doctor based on the child's body weight.

Country of origin

INDIA

Manufacturer/Marketer address

11/12, Udyog Nagar, S. V. Road, Goregaon (W), Mumbai- 400104.
Other Info - THE0180

Author Details

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FAQs

Themiset Injection 5 ml is used to treat nausea and vomiting.
Themiset Injection 5 ml contains Palonosetron which works by blocking the action of serotonin, a chemical that stimulates the vomiting centre (chemoreceptor trigger zone – CTZ) located in the brain. Thus, it prevents nausea and vomiting.
You are not recommended to take erythromycin with Themiset Injection 5 ml as it may increase the risk of severe irregular heart rhythm. However, please consult your doctor before taking other medicines with Themiset Injection 5 ml.
Themiset Injection 5 ml may cause constipation as a side effect. It is not necessary for everyone taking Themiset Injection 5 ml to experience this side effect. However, if the condition persists or worsens, please consult a doctor.
Themiset Injection 5 ml should be used with caution in patients suffering from heart problems as it may worsen the condition. Therefore, inform your doctor if you have any heart problems before taking have Themiset Injection 5 ml so that the dose may be adjusted appropriately.

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