Talmin D 250 mg/350 mg Tablet belongs to the group of medicines called 'muscle relaxants' used to reduce and relieve muscle spasms due to pain and injury. Besides this, it also treats tetanus conditions (lockjaw) which are characterized by painful tightening muscles. Muscle spasm is the sudden, painful, involuntary muscle contractions which occurs when the nerve impulses that control the muscle movements are damaged or interrupted. Tetanus is a nervous system disorder leading to painful muscle contraction, mainly affecting the jaw and neck muscles. 

Talmin D 250 mg/350 mg Tablet is a combination of two drugs: Paracetamol (mild analgesic and fever reducer) and Methocarbamol (muscle relaxant). Paracetamol acts as a mild analgesic and antipyretic, which inhibits the release of chemical mediators (prostaglandin) that cause pain, thereby lowering pain, inflammation and fever. On the other hand, Methocarbamol is a muscle relaxant that works by blocking pain sensation (nerve impulse) sent to the brain. Thus, Talmin D 250 mg/350 mg Tablet works on the central nervous system (spinal cord and brain), thereby maintaining muscle strength and relieving muscle spasms or stiffness. 

Take Talmin D 250 mg/350 mg Tablet as prescribed by your doctor. Take Talmin D 250 mg/350 mg Tablet for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side effects, such as sleepiness, drowsiness, nausea, headache, weakness, and diarrhoea. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are suggested to talk to your doctor if you experience these side effects persistently.

Continue taking Talmin D 250 mg/350 mg Tablet for as long as your doctor has prescribed it. Consult your doctor before taking Talmin D 250 mg/350 mg Tablet if you are pregnant or breastfeeding. Your doctor will prescribe Talmin D 250 mg/350 mg Tablet only if the benefits outweigh the risks. Talmin D 250 mg/350 mg Tablet is not recommended for children unless prescribed by a doctor. Inform your doctor about your current medicines and your health condition to rule out any unpleasant side effects. Do not take Talmin D 250 mg/350 mg Tablet with other drugs like antidepressants that make you sleepy or slow your breathing can cause dangerous side effects or death. Avoid intake of Talmin D 250 mg/350 mg Tablet in kidney disease conditions, seizures attack (fits/epilepsy) and muscle problems (myasthenia gravis). 

Talmin D 250 mg/350 mg Tablet consists of two medicines: Paracetamol (mild analgesic) and Methocarbamol (muscle relaxant). Paracetamol acts as a mild analgesic and fever reducer, which prevents the release of chemical mediators (prostaglandin) that cause pain, inflammation and fever. On the other hand, Methocarbamol is a muscle relaxant that stops sending a pain signal to the brain, relieving muscle stiffness or muscle spasm along with pain and injury. Together, Talmin D 250 mg/350 mg Tablet treats painful muscle spasms associated with short-term muscle disorders, like spasms in the lower back, injuries, sprains and strains. 

• Nausea
• Vomiting
• Heartburn
• Stomach pain
• Diarrhea
• Loss of appetite
• Sleepiness
• Drowsiness

Do not take Talmin D 250 mg/350 mg Tablet if you are allergic to paracetamol, methocarbamol or any of its contents. Talk to your doctor before taking Talmin D 250 mg/350 mg Tablet if you have kidney or liver problems, myasthenia gravis (muscle weakness) and seizures (fits). Consult your doctor before taking Talmin D 250 mg/350 mg Tablet if you are pregnant or breastfeeding. Your doctor will prescribe Talmin D 250 mg/350 mg Tablet only if the benefits outweigh the risks. Talmin D 250 mg/350 mg Tablet is not recommended for children. Inform your doctor about all the medicines you are taking and your health condition to rule out any unpleasant side effects. Inform your doctor that you are taking Talmin D 250 mg/350 mg Tablet if you are experiencing any operation which requires a general anaesthetic. Talmin D 250 mg/350 mg Tablet may cause drowsiness and sleepiness, so it is advised not to drive a car or operate machinery. Consumption of alcohol should be avoided as it may lead to excessive drowsiness and sleepiness.

Drug-Drug Interaction: Talmin D 250 mg/350 mg Tablet may interact with antiepileptics (carbamazepine, oxcarbazepine, lamotrigine, topiramate, zonisamide), appetite suppressants (orlistat), anticholinergic (benztropine, clidinium, cyclopentolate, dicyclomine), antianxiety (alprazolam, chlordiazepoxide, clonazepam, lorazepam, diazepam), antidepressants (amitriptyline, amoxapine, clomipramine, imipramine, nortriptyline).

Drug-Food Interaction: Avoid alcohol intake and tobacco consumption with Talmin D 250 mg/350 mg Tablet as it may cause increased drowsiness, dizziness and lack of concentration.

Drug-Disease Interaction: Talmin D 250 mg/350 mg Tablet may have interactions with liver disease, kidney dysfunction, seizures (fits), and autonomic dysreflexia (spinal cord injury).

• CARBAMAZEPINE
• OXCARBAZEPINE
• LAMOTRIGINE
• TOPIRAMATE
• ZONISAMIDE
• ORLISTAT
• BENZTROPINE MESYLATE
• CLIDINIUM+CHLORDIAZEPOXIDE
• CYCLOPENTOLATE
• DICYCLOMINE
• ALPRAZOLAM
• CLONAZEPAM
• LORAZEPAM
• DIAZEPAM
• AMITRIPTYLINE
• AMOXAPINE
• CLOMIPHENE
• IMIPRAMINE
• NORTRIPTYLINE

• Exercising regularly helps in muscle stretching so that they are less likely to spasm, tear and sprain. Mild exercises such as jogging and walking are helpful for muscle stretching.

• Deep tissue massages with the help of muscle massagers are considered helpful. 

• Avoid wearing tight-fitting clothes; instead, wear loose garments.

• Rest well, and get plenty of sleep (at least 8 hours for adults). 

• Hot or cold therapy can help treat muscle spasms. Apply an ice pack or hot pack on the muscle for 15-20 minutes. 

• Try to include glycine (protein) in your daily diet, which is good food for your muscle.

• Let your doctor and the laboratory staff know if you are using Talmin D 250 mg/350 mg Tablet since Methocarbamol may interfere with laboratory tests.

• You may need to reduce your dose after the first 2 or 3 days of treatment. Follow your doctor's instructions regarding the number of tablets you take each day.

Muscle spasm: The sudden involuntary contractions of the muscle can be painful and uncomfortable. When the nerve impulses that control the muscle movements are damaged or interrupted, it could lead to muscle spasms. Symptoms include muscle tightness, joint stiffness, unusual posture, difficulty moving, and pain in affected muscles and joints. Fatigue (weakness), stress, extreme heat or cold, infection, and tight clothing can trigger muscle spasms. Muscle relaxants and exercise can treat muscle spasms. Muscle relaxants sedate the muscle and help in inhibiting painful contractions. Exercise helps in muscle stretching, making them less likely to spasm, tear, and sprain.

Tetanus: Also known as Lockjaw, it is a bacterial infection caused by Clostridium tetani. After invading our bodies, these bacteria start to produce a poison (toxin) that causes painful muscle contractions. It causes a person’s neck or jaw muscles to lock, making it hard to open the mouth or swallow food/drinks.